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Volumn 92, Issue 2, 2003, Pages 203-217

Barriers to nonviral gene delivery

Author keywords

Cationic lipid; Gene delivery; Mechanism; Nonviral; Polymer

Indexed keywords

LIPID; PLASMID DNA;

EID: 0037309716     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10286     Document Type: Short Survey
Times cited : (457)

References (154)
  • 1
    • 0015492624 scopus 로고
    • Gene therapy for human genetic disease?
    • Friedmann T, Roblin R. 1972. Gene therapy for human genetic disease? Science 175(25):949-955.
    • (1972) Science , vol.175 , Issue.25 , pp. 949-955
    • Friedmann, T.1    Roblin, R.2
  • 2
    • 85031258833 scopus 로고    scopus 로고
    • http://www.wiley.com/legacy/wileychi/genmed/clinical/.
  • 3
    • 0004042912 scopus 로고    scopus 로고
    • Cold Spring Harbor, NY: Cold Spring Harbor Laboratories Press
    • Friedmann T, editor. 1999. The development of human gene therapy. Cold Spring Harbor, NY: Cold Spring Harbor Laboratories Press. p 729.
    • (1999) The Development of Human Gene Therapy , pp. 729
    • Friedmann, T.1
  • 4
    • 0034841690 scopus 로고    scopus 로고
    • Efficient in-vitro transfer of a 60-Mb mammalian artificial chromosome into murine and hamster cells using cationic lipids and dendrimers
    • de Jong G, Telenius A, Vanderbyl S, Meitz A, Drayer J. 2001. Efficient in-vitro transfer of a 60-Mb mammalian artificial chromosome into murine and hamster cells using cationic lipids and dendrimers. Chromosome Res 9(6):475-485.
    • (2001) Chromosome Res , vol.9 , Issue.6 , pp. 475-485
    • De Jong, G.1    Telenius, A.2    Vanderbyl, S.3    Meitz, A.4    Drayer, J.5
  • 6
    • 0032732516 scopus 로고    scopus 로고
    • LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth
    • Whitmore M, Li S, Huang L. 1999. LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth. Gene Ther 6(11):1867-1875.
    • (1999) Gene Ther , vol.6 , Issue.11 , pp. 1867-1875
    • Whitmore, M.1    Li, S.2    Huang, L.3
  • 7
    • 0010276632 scopus 로고    scopus 로고
    • Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously
    • Dow SW, Fradkin LG, Liggitt DH, Willson AP, Heath TD, Potter TA. 1999. Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously. J Immunol 163(3):1552-1561.
    • (1999) J Immunol , vol.163 , Issue.3 , pp. 1552-1561
    • Dow, S.W.1    Fradkin, L.G.2    Liggitt, D.H.3    Willson, A.P.4    Heath, T.D.5    Potter, T.A.6
  • 9
    • 0035668040 scopus 로고    scopus 로고
    • Systemic administration of LPD prepared with CpG oligonucleotides inhibits the growth of established pulmonary metastases by stimulating innate and acquired antitumor immune responses
    • Whitmore MM, Li S, Falo L, Jr, Huang L. 2001. Systemic administration of LPD prepared with CpG oligonucleotides inhibits the growth of established pulmonary metastases by stimulating innate and acquired antitumor immune responses. Cancer Immunol Immunother 50(10):503-514.
    • (2001) Cancer Immunol Immunother , vol.50 , Issue.10 , pp. 503-514
    • Whitmore, M.M.1    Li, S.2    Falo L., Jr.3    Huang, L.4
  • 10
    • 0036110686 scopus 로고    scopus 로고
    • Quantitative analysis of correlation between number of nuclear plasmids and gene expression activity after transfection with cationic liposomes
    • Tachibana R, Harashima H, Ide N, Ukitsu S, Ohta Y, Suzuki N, Kikuchi H, Shinohara Y, Kiwada H. 2002. Quantitative analysis of correlation between number of nuclear plasmids and gene expression activity after transfection with cationic liposomes. Pharm Res 19(4):377-381.
    • (2002) Pharm Res , vol.19 , Issue.4 , pp. 377-381
    • Tachibana, R.1    Harashima, H.2    Ide, N.3    Ukitsu, S.4    Ohta, Y.5    Suzuki, N.6    Kikuchi, H.7    Shinohara, Y.8    Kiwada, H.9
  • 11
    • 0024978864 scopus 로고
    • Cationic liposome-mediated transfection
    • Felgner PL, Ringold GM. 1989. Cationic liposome-mediated transfection. Nature 337(6205):387-388.
    • (1989) Nature , vol.337 , Issue.6205 , pp. 387-388
    • Felgner, P.L.1    Ringold, G.M.2
  • 12
    • 0034167974 scopus 로고    scopus 로고
    • Nuclear-associated plasmid, but not cell-associated plasmid, is correlated with transgene expression in cultured mammalian cells
    • James MB, Giorgio TD. 2000. Nuclear-associated plasmid, but not cell-associated plasmid, is correlated with transgene expression in cultured mammalian cells. Mol Ther 1(4):339-346.
    • (2000) Mol Ther , vol.1 , Issue.4 , pp. 339-346
    • James, M.B.1    Giorgio, T.D.2
  • 13
    • 0034670157 scopus 로고    scopus 로고
    • The role of CpG motifs in immunostimulation and gene therapy
    • Scheule RK. 2000. The role of CpG motifs in immunostimulation and gene therapy. Adv Drug Deliv Rev 44(2-3):119-134.
    • (2000) Adv Drug Deliv Rev , vol.44 , Issue.2-3 , pp. 119-134
    • Scheule, R.K.1
  • 15
  • 16
    • 0034149827 scopus 로고    scopus 로고
    • Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs
    • Yew NS, Zhao H, Wu IH, Song A, Tousignant JD, Przybylska M, Cheng SH. 2000. Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs. Mol Ther 1(3):255-262.
    • (2000) Mol Ther , vol.1 , Issue.3 , pp. 255-262
    • Yew, N.S.1    Zhao, H.2    Wu, I.H.3    Song, A.4    Tousignant, J.D.5    Przybylska, M.6    Cheng, S.H.7
  • 18
    • 0031806722 scopus 로고    scopus 로고
    • A physicochemical approach for predicting the effectiveness of peptide-based gene delivery systems for use in plasmid-based gene therapy
    • Duguid JG, Li C, Shi M, Logan MJ, Alila H, Rolland A, Tomlinson E, Sparrow JT, Smith LC. 1998. A physicochemical approach for predicting the effectiveness of peptide-based gene delivery systems for use in plasmid-based gene therapy. Biophys J 74(6):2802-2814.
    • (1998) Biophys J , vol.74 , Issue.6 , pp. 2802-2814
    • Duguid, J.G.1    Li, C.2    Shi, M.3    Logan, M.J.4    Alila, H.5    Rolland, A.6    Tomlinson, E.7    Sparrow, J.T.8    Smith, L.C.9
  • 19
    • 0012918309 scopus 로고    scopus 로고
    • Light scattering techniques for characterization of synthetic gene therapy vectors
    • Wiethoff CM, Middaugh CR. 2001. Light scattering techniques for characterization of synthetic gene therapy vectors. Methods Mol Med 65:349-376.
    • (2001) Methods Mol Med , vol.65 , pp. 349-376
    • Wiethoff, C.M.1    Middaugh, C.R.2
  • 20
    • 0033031584 scopus 로고    scopus 로고
    • Lamellarity of cationic liposomes and mode of preparation of lipoplexes affect transfection efficiency
    • Zuidam NJ, Hirsch-Lerner D, Margulies S, Barenholz Y. 1999. Lamellarity of cationic liposomes and mode of preparation of lipoplexes affect transfection efficiency. Biochim Biophys Acta 1419(2):207-220.
    • (1999) Biochim Biophys Acta , vol.1419 , Issue.2 , pp. 207-220
    • Zuidam, N.J.1    Hirsch-Lerner, D.2    Margulies, S.3    Barenholz, Y.4
  • 21
    • 0028072689 scopus 로고
    • New structures in complex formation between DNA and cationic liposomes visualized by freeze-fracture electron microscopy
    • Sternberg B, Sorgi FL, Huang L. 1994. New structures in complex formation between DNA and cationic liposomes visualized by freeze-fracture electron microscopy. FEBS Lett 356(2-3):361-366.
    • (1994) FEBS Lett , vol.356 , Issue.2-3 , pp. 361-366
    • Sternberg, B.1    Sorgi, F.L.2    Huang, L.3
  • 22
    • 0033050727 scopus 로고    scopus 로고
    • Physicochemical characterization and purification of cationic lipoplexes
    • Xu Y, Hui SW, Frederik P, Szoka FC, Jr. 1999. Physicochemical characterization and purification of cationic lipoplexes. Biophys J 77(1):341-353.
    • (1999) Biophys J , vol.77 , Issue.1 , pp. 341-353
    • Xu, Y.1    Hui, S.W.2    Frederik, P.3    Szoka F.C., Jr.4
  • 23
    • 0030757526 scopus 로고    scopus 로고
    • Nanoscopic structure of DNA condensed for gene delivery
    • Dunlap DD, Maggi A, Soria MR, Monaco L. 1997. Nanoscopic structure of DNA condensed for gene delivery. Nucleic Acids Res 25(15):3095-3101.
    • (1997) Nucleic Acids Res , vol.25 , Issue.15 , pp. 3095-3101
    • Dunlap, D.D.1    Maggi, A.2    Soria, M.R.3    Monaco, L.4
  • 25
    • 0034657622 scopus 로고    scopus 로고
    • Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression
    • Sakurai F, Inoue R, Nishino Y, Okuda A, Matsumoto O, Taga T, Yamashita F, Takakura Y, Hashida M. 2000. Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression. J Controlled Release 66(2-3):255-269.
    • (2000) J Controlled Release , vol.66 , Issue.2-3 , pp. 255-269
    • Sakurai, F.1    Inoue, R.2    Nishino, Y.3    Okuda, A.4    Matsumoto, O.5    Taga, T.6    Yamashita, F.7    Takakura, Y.8    Hashida, M.9
  • 27
    • 0032479572 scopus 로고    scopus 로고
    • An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery
    • Koltover I, Salditt T, Radler JO, Safinya CR. 1998. An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery. Science 281(5373):78-81.
    • (1998) Science , vol.281 , Issue.5373 , pp. 78-81
    • Koltover, I.1    Salditt, T.2    Radler, J.O.3    Safinya, C.R.4
  • 28
    • 0031036238 scopus 로고    scopus 로고
    • Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes
    • Radler JO, Koltover I, Salditt T, Safinya CR. 1997. Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes. Science 275(5301):810-814.
    • (1997) Science , vol.275 , Issue.5301 , pp. 810-814
    • Radler, J.O.1    Koltover, I.2    Salditt, T.3    Safinya, C.R.4
  • 29
    • 0035861658 scopus 로고    scopus 로고
    • Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine-DNA complexes and the efficiency of gene delivery
    • Smisterova J, Wagenaar A, Stuart MC, Polushkin E, ten Brinke G, Hulst R, Engberts JB, Hoekstra D. 2001. Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine-DNA complexes and the efficiency of gene delivery. J Biol Chem 276(50):47615-47622.
    • (2001) J Biol Chem , vol.276 , Issue.50 , pp. 47615-47622
    • Smisterova, J.1    Wagenaar, A.2    Stuart, M.C.3    Polushkin, E.4    Ten Brinke, G.5    Hulst, R.6    Engberts, J.B.7    Hoekstra, D.8
  • 30
    • 0031655828 scopus 로고    scopus 로고
    • Evidence for three-dimensional interlayer correlations in cationic lipid-DNA complexes as observed by cryo-electron microscopy
    • Battersby BJ, Grimm R, Huebner S, Cevc G. 1998. Evidence for three-dimensional interlayer correlations in cationic lipid-DNA complexes as observed by cryo-electron microscopy. Biochim Biophys Acta 1372(2):379-383.
    • (1998) Biochim Biophys Acta , vol.1372 , Issue.2 , pp. 379-383
    • Battersby, B.J.1    Grimm, R.2    Huebner, S.3    Cevc, G.4
  • 31
    • 0033607252 scopus 로고    scopus 로고
    • DNA packing in stable lipid complexes designed for gene transfer imitates DNA compaction in bacteriophage
    • Schmutz M, Durand D, Debin A, Palvadeau Y, Etienne A, Thierry AR. 1999. DNA packing in stable lipid complexes designed for gene transfer imitates DNA compaction in bacteriophage. Proc Natl Acad Sci USA 96(22):12293-12298.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.22 , pp. 12293-12298
    • Schmutz, M.1    Durand, D.2    Debin, A.3    Palvadeau, Y.4    Etienne, A.5    Thierry, A.R.6
  • 32
    • 0033064122 scopus 로고    scopus 로고
    • Lipid-DNA complex formation: Reorganization and rupture of lipid vesicles in the presence of DNA as observed by cryoelectron microscopy
    • Huebner S, Battersby BJ, Grimm R, Cevc G. 1999. Lipid-DNA complex formation: Reorganization and rupture of lipid vesicles in the presence of DNA as observed by cryoelectron microscopy. Biophys J 76(6):3158-3166.
    • (1999) Biophys J , vol.76 , Issue.6 , pp. 3158-3166
    • Huebner, S.1    Battersby, B.J.2    Grimm, R.3    Cevc, G.4
  • 33
    • 0035861585 scopus 로고    scopus 로고
    • Phase behavior, DNA ordering, and size instability of cationic lipoplexes. Relevance to optimal transfection activity
    • Simberg D, Danino D, Talmon Y, Minsky A, Ferrari ME, Wheeler CJ, Barenholz Y. 2001. Phase behavior, DNA ordering, and size instability of cationic lipoplexes. Relevance to optimal transfection activity. J Biol Chem 276(50):47453-47459.
    • (2001) J Biol Chem , vol.276 , Issue.50 , pp. 47453-47459
    • Simberg, D.1    Danino, D.2    Talmon, Y.3    Minsky, A.4    Ferrari, M.E.5    Wheeler, C.J.6    Barenholz, Y.7
  • 34
    • 0029039731 scopus 로고
    • Complexes between cationic liposomes and DNA visualized by cryo-TEM
    • Gustafsson J, Arvidson G, Karlsson G, Almgren M. 1995. Complexes between cationic liposomes and DNA visualized by cryo-TEM. Biochim Biophys Acta 1235(2):305-312.
    • (1995) Biochim Biophys Acta , vol.1235 , Issue.2 , pp. 305-312
    • Gustafsson, J.1    Arvidson, G.2    Karlsson, G.3    Almgren, M.4
  • 35
    • 0036174061 scopus 로고    scopus 로고
    • Differential scanning calorimetric studies of the thermal stability of plasmid DNA complexed with cationic lipids and polymers
    • Lobo BA, Rogers SA, Choosakoonkriang S, Smith JG, Koe G, Middaugh CR. 2002. Differential scanning calorimetric studies of the thermal stability of plasmid DNA complexed with cationic lipids and polymers. J Pharm Sci 91(2):454-466.
    • (2002) J Pharm Sci , vol.91 , Issue.2 , pp. 454-466
    • Lobo, B.A.1    Rogers, S.A.2    Choosakoonkriang, S.3    Smith, J.G.4    Koe, G.5    Middaugh, C.R.6
  • 36
    • 0030570806 scopus 로고    scopus 로고
    • Conformational change in DNA induced by cationic bilayer membranes
    • Akao T, Fukumoto T, Ihara H, Ito A. 1996. Conformational change in DNA induced by cationic bilayer membranes. FEBS Lett 391(1-2):215-218.
    • (1996) FEBS Lett , vol.391 , Issue.1-2 , pp. 215-218
    • Akao, T.1    Fukumoto, T.2    Ihara, H.3    Ito, A.4
  • 38
    • 0035980089 scopus 로고    scopus 로고
    • The potential role of proteoglycans in cationic lipid-mediated gene delivery. Studies of the interaction of cationic lipid-DNA complexes with model glycosaminoglycans
    • Wiethoff CM, Smith JG, Koe GS, Middaugh CR. 2001. The potential role of proteoglycans in cationic lipid-mediated gene delivery. Studies of the interaction of cationic lipid-DNA complexes with model glycosaminoglycans. J Biol Chem 276(35):32806-32813.
    • (2001) J Biol Chem , vol.276 , Issue.35 , pp. 32806-32813
    • Wiethoff, C.M.1    Smith, J.G.2    Koe, G.S.3    Middaugh, C.R.4
  • 39
    • 0033384343 scopus 로고    scopus 로고
    • Hydration of lipoplexes commonly used in gene delivery: Follow-up by laurdan fluorescence changes and quantification by differential scanning calorimetry
    • Hirsch-Lerner D, Barenholz Y. 1999. Hydration of lipoplexes commonly used in gene delivery: Follow-up by laurdan fluorescence changes and quantification by differential scanning calorimetry. Biochim Biophys Acta 1461(1):47-57.
    • (1999) Biochim Biophys Acta , vol.1461 , Issue.1 , pp. 47-57
    • Hirsch-Lerner, D.1    Barenholz, Y.2
  • 40
    • 0030716259 scopus 로고    scopus 로고
    • Electrostatic parameters of cationic liposomes commonly used for gene delivery as determined by 4-heptadecyl-7-hydroxycoumarin
    • Zuidam NJ, Barenholz Y. 1997. Electrostatic parameters of cationic liposomes commonly used for gene delivery as determined by 4-heptadecyl-7-hydroxycoumarin. Biochim Biophys Acta 1329 (2):211-222.
    • (1997) Biochim Biophys Acta , vol.1329 , Issue.2 , pp. 211-222
    • Zuidam, N.J.1    Barenholz, Y.2
  • 41
    • 0029049810 scopus 로고
    • The fate of plasmid DNA after intravenous injection in mice: Involvement of scavenger receptors in its hepatic uptake
    • Kawabata K, Takakura Y, Hashida M. 1995. The fate of plasmid DNA after intravenous injection in mice: Involvement of scavenger receptors in its hepatic uptake. Pharm Res 12(6):825-830.
    • (1995) Pharm Res , vol.12 , Issue.6 , pp. 825-830
    • Kawabata, K.1    Takakura, Y.2    Hashida, M.3
  • 42
    • 0029891916 scopus 로고    scopus 로고
    • Polyvinyl derivatives as novel interactive polymers for controlled gene delivery to muscle
    • Mumper RJ, Duguid JG, Anwer K, Barron MK, Nitta H, Rolland AP. 1996. Polyvinyl derivatives as novel interactive polymers for controlled gene delivery to muscle. Pharm Res 13(5):701-709.
    • (1996) Pharm Res , vol.13 , Issue.5 , pp. 701-709
    • Mumper, R.J.1    Duguid, J.G.2    Anwer, K.3    Barron, M.K.4    Nitta, H.5    Rolland, A.P.6
  • 43
    • 0032962978 scopus 로고    scopus 로고
    • Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: Implications for intravenous lipofection
    • Li S, Tseng WC, Stolz DB, Wu SP, Watkins SC, Huang L. 1999. Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: Implications for intravenous lipofection. Gene Ther 6(4):585-594.
    • (1999) Gene Ther , vol.6 , Issue.4 , pp. 585-594
    • Li, S.1    Tseng, W.C.2    Stolz, D.B.3    Wu, S.P.4    Watkins, S.C.5    Huang, L.6
  • 44
    • 0035206125 scopus 로고    scopus 로고
    • Cross-linked low molecular weight glycopeptide-mediated gene delivery: Relationship between DNA metabolic stability and the level of transient gene expression in vivo
    • Yang Y, Park Y, Man S, Liu Y, Rice KG. 2001. Cross-linked low molecular weight glycopeptide-mediated gene delivery: Relationship between DNA metabolic stability and the level of transient gene expression in vivo. J Pharm Sci 90(12):2010-2022.
    • (2001) J Pharm Sci , vol.90 , Issue.12 , pp. 2010-2022
    • Yang, Y.1    Park, Y.2    Man, S.3    Liu, Y.4    Rice, K.G.5
  • 45
    • 0032783825 scopus 로고    scopus 로고
    • Metabolic stability of glutaraldehyde cross-linked peptide DNA condensates
    • Adami RC, Rice KG. 1999. Metabolic stability of glutaraldehyde cross-linked peptide DNA condensates. J Pharm Sci 88(8):739-746.
    • (1999) J Pharm Sci , vol.88 , Issue.8 , pp. 739-746
    • Adami, R.C.1    Rice, K.G.2
  • 46
    • 0032473394 scopus 로고    scopus 로고
    • Protective interactive noncondensing (PINC) polymers for enhanced plasmid distribution and expression in rat skeletal muscle
    • Mumper RJ, Wang J, Klakamp SL, Nitta H, Anwer K, Tagliaferri F, Rolland AP. 1998. Protective interactive noncondensing (PINC) polymers for enhanced plasmid distribution and expression in rat skeletal muscle. J Controlled Release 52(1-2):191-203.
    • (1998) J Controlled Release , vol.52 , Issue.1-2 , pp. 191-203
    • Mumper, R.J.1    Wang, J.2    Klakamp, S.L.3    Nitta, H.4    Anwer, K.5    Tagliaferri, F.6    Rolland, A.P.7
  • 47
    • 0032473414 scopus 로고    scopus 로고
    • Plasmid delivery to muscle: Recent advances in polymer delivery systems
    • Rolland AP, Mumper RJ. Plasmid delivery to muscle: Recent advances in polymer delivery systems. Adv Drug Deliv Rev 30(1-3):151-172.
    • Adv Drug Deliv Rev , vol.30 , Issue.1-3 , pp. 151-172
    • Rolland, A.P.1    Mumper, R.J.2
  • 48
    • 0031023264 scopus 로고    scopus 로고
    • Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery
    • Hong K, Zheng W, Baker A, Papahadjopoulos D. 1997. Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery. FEBS Lett 400(2):233-237.
    • (1997) FEBS Lett , vol.400 , Issue.2 , pp. 233-237
    • Hong, K.1    Zheng, W.2    Baker, A.3    Papahadjopoulos, D.4
  • 49
    • 0033036668 scopus 로고    scopus 로고
    • Stabilized plasmid-lipid particles: Factors influencing plasmid entrapment and transfection properties
    • Mok KW, Lam AM, Cullis PR. Stabilized plasmid-lipid particles: Factors influencing plasmid entrapment and transfection properties. Biochim Biophys Acta 1419(2):137-150.
    • Biochim Biophys Acta , vol.1419 , Issue.2 , pp. 137-150
    • Mok, K.W.1    Lam, A.M.2    Cullis, P.R.3
  • 52
    • 85047697141 scopus 로고    scopus 로고
    • Pegylated GL67 lipoplexes retain their gene transfection activity after exposure to components of CF mucus
    • Sanders NN, De Smedt SC, Cheng SH, Demeester J. 2002. Pegylated GL67 lipoplexes retain their gene transfection activity after exposure to components of CF mucus. Gene Ther 9(6):363-371.
    • (2002) Gene Ther , vol.9 , Issue.6 , pp. 363-371
    • Sanders, N.N.1    De Smedt, S.C.2    Cheng, S.H.3    Demeester, J.4
  • 54
    • 0343938838 scopus 로고    scopus 로고
    • DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers
    • Oupicky D, Konak C, Ulbrich K, Wolfert MA, Seymour LW. 2000. DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers. J Controlled Release 65(1-2):149-171.
    • (2000) J Controlled Release , vol.65 , Issue.1-2 , pp. 149-171
    • Oupicky, D.1    Konak, C.2    Ulbrich, K.3    Wolfert, M.A.4    Seymour, L.W.5
  • 55
    • 0032836717 scopus 로고    scopus 로고
    • Formulation of highly soluble poly(ethylene glycol)-peptide DNA condensates
    • Kwok KY, McKenzie DL, Evers DL, Rice KG. 1999. Formulation of highly soluble poly(ethylene glycol)-peptide DNA condensates. J Pharm Sci 88(10):996-1003.
    • (1999) J Pharm Sci , vol.88 , Issue.10 , pp. 996-1003
    • Kwok, K.Y.1    McKenzie, D.L.2    Evers, D.L.3    Rice, K.G.4
  • 56
    • 0033811108 scopus 로고    scopus 로고
    • Biodistribution, metabolism, and in vivo gene expression of low molecular weight glycopeptide polyethylene glycol peptide DNA co-condensates
    • Collard WT, Yang Y, Kwok KY, Park Y, Rice KG. 2000. Biodistribution, metabolism, and in vivo gene expression of low molecular weight glycopeptide polyethylene glycol peptide DNA co-condensates. J Pharm Sci 89(4):499-512.
    • (2000) J Pharm Sci , vol.89 , Issue.4 , pp. 499-512
    • Collard, W.T.1    Yang, Y.2    Kwok, K.Y.3    Park, Y.4    Rice, K.G.5
  • 57
    • 0036009634 scopus 로고    scopus 로고
    • Synthesis of sulfhydryl cross-linking poly(ethylene, glycol)-peptides and glycopeptides as carriers for gene delivery
    • Park Y, Kwok KY, Boukarim C, Rice KG. 2002. Synthesis of sulfhydryl cross-linking poly(ethylene, glycol)-peptides and glycopeptides as carriers for gene delivery. Bioconjug Chem 13(2):232-239.
    • (2002) Bioconjug Chem , vol.13 , Issue.2 , pp. 232-239
    • Park, Y.1    Kwok, K.Y.2    Boukarim, C.3    Rice, K.G.4
  • 59
    • 0034616214 scopus 로고    scopus 로고
    • A potent new class of reductively activated peptide gene delivery agents
    • McKenzie DL, Kwok KY, Rice KG. 2000. A potent new class of reductively activated peptide gene delivery agents. J Biol Chem 275(14):9970-9977.
    • (2000) J Biol Chem , vol.275 , Issue.14 , pp. 9970-9977
    • McKenzie, D.L.1    Kwok, K.Y.2    Rice, K.G.3
  • 60
    • 0032805569 scopus 로고    scopus 로고
    • Phase diagram, stability, and overcharging of lamellar cationic lipid-DNA self-assembled complexes
    • Koltover I, Salditt T, Safinya CR. 1999. Phase diagram, stability, and overcharging of lamellar cationic lipid-DNA self-assembled complexes. Biophys J 77(2):915-924.
    • (1999) Biophys J , vol.77 , Issue.2 , pp. 915-924
    • Koltover, I.1    Salditt, T.2    Safinya, C.R.3
  • 61
    • 0344378203 scopus 로고    scopus 로고
    • Effect of albumin and polyanion on the structure of DNA complexes with polycation containing hydrophilic nonionic block
    • Oupicky D, Konak C, Dash PR, Seymour LW, Ulbrich K. 1999. Effect of albumin and polyanion on the structure of DNA complexes with polycation containing hydrophilic nonionic block. Bioconjug Chem 10(5):764-772.
    • (1999) Bioconjug Chem , vol.10 , Issue.5 , pp. 764-772
    • Oupicky, D.1    Konak, C.2    Dash, P.R.3    Seymour, L.W.4    Ulbrich, K.5
  • 62
    • 0344389048 scopus 로고    scopus 로고
    • Interactions of polymeric and liposomal gene delivery systems with extracellular glycosamino-glycans: Physicochemical and transfection studies
    • Ruponen M, Yla-Herttuala S, Urtti A. 1999. Interactions of polymeric and liposomal gene delivery systems with extracellular glycosamino-glycans: physicochemical and transfection studies. Biochim Biophys Acta 1415(2):331-341.
    • (1999) Biochim Biophys Acta , vol.1415 , Issue.2 , pp. 331-341
    • Ruponen, M.1    Yla-Herttuala, S.2    Urtti, A.3
  • 63
    • 0031983912 scopus 로고    scopus 로고
    • Inclusion of cholesterol in DOTAP transfection complexes increases the delivery of DNA to cells in vitro in the presence of serum
    • Crook K, Stevenson BJ, Dubouchet M, Porteous DJ. 1998. Inclusion of cholesterol in DOTAP transfection complexes increases the delivery of DNA to cells in vitro in the presence of serum. Gene Ther 5(1):137-143.
    • (1998) Gene Ther , vol.5 , Issue.1 , pp. 137-143
    • Crook, K.1    Stevenson, B.J.2    Dubouchet, M.3    Porteous, D.J.4
  • 64
    • 0034891884 scopus 로고    scopus 로고
    • Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes Containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system
    • Sakurai F, Nishioka T, Yamashita F, Takakura Y, Hashida M. 2001. Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes Containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system. Eur J Pharm Biopharm 52(2):165-172.
    • (2001) Eur J Pharm Biopharm , vol.52 , Issue.2 , pp. 165-172
    • Sakurai, F.1    Nishioka, T.2    Yamashita, F.3    Takakura, Y.4    Hashida, M.5
  • 66
    • 0032931623 scopus 로고    scopus 로고
    • Lipoplex size is a major determinant of in vitro lipofection efficiency
    • Ross PC, Hui SW. 1999. Lipoplex size is a major determinant of in vitro lipofection efficiency. Gene Ther 6(4):651-659.
    • (1999) Gene Ther , vol.6 , Issue.4 , pp. 651-659
    • Ross, P.C.1    Hui, S.W.2
  • 68
    • 0026744148 scopus 로고
    • Cell surface heparan sulfate proteoglycans
    • Yanagishita M, Hascall VC. 1992. Cell surface heparan sulfate proteoglycans. J Biol Chem 267(14):9451-9454.
    • (1992) J Biol Chem , vol.267 , Issue.14 , pp. 9451-9454
    • Yanagishita, M.1    Hascall, V.C.2
  • 70
    • 0026026623 scopus 로고
    • Glycoprotein C of herpes simplex virus type 1 plays a principal role in the adsorption of virus to cells and in infectivity
    • Herold BC, WuDunn D, Soltys N, Spear PG. 1991. Glycoprotein C of herpes simplex virus type 1 plays a principal role in the adsorption of virus to cells and in infectivity. J Virol 65(3):1090-1098.
    • (1991) J Virol , vol.65 , Issue.3 , pp. 1090-1098
    • Herold, B.C.1    WuDunn, D.2    Soltys, N.3    Spear, P.G.4
  • 71
    • 0031906147 scopus 로고    scopus 로고
    • Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions
    • Summerford C, Samulski RJ. 1998. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J Virol 72(2):1438-1445.
    • (1998) J Virol , vol.72 , Issue.2 , pp. 1438-1445
    • Summerford, C.1    Samulski, R.J.2
  • 72
    • 0034654569 scopus 로고    scopus 로고
    • Heparan sulfate glycosaminoglycans are involved in adenovirus type 5 and 2-host cell interactions
    • Dechecchi MC, Tamanini A, Bonizzato A, Cabrini G. 2000. Heparan sulfate glycosaminoglycans are involved in adenovirus type 5 and 2-host cell interactions. Virology 268(2):382-390.
    • (2000) Virology , vol.268 , Issue.2 , pp. 382-390
    • Dechecchi, M.C.1    Tamanini, A.2    Bonizzato, A.3    Cabrini, G.4
  • 73
    • 0029981092 scopus 로고    scopus 로고
    • Evidence for the role of proteoglycans in cation-mediated gene transfer
    • Mislick KA, Baldeschwieler JD. 1996. Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc Natl Acad Sci USA 93(22):12349-12354.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.22 , pp. 12349-12354
    • Mislick, K.A.1    Baldeschwieler, J.D.2
  • 74
    • 0033198859 scopus 로고    scopus 로고
    • Protective role for proteoglycans against cationic lipid cytotoxicity allowing optimal transfection efficiency in vitro
    • Belting M, Petersson P. 1999. Protective role for proteoglycans against cationic lipid cytotoxicity allowing optimal transfection efficiency in vitro. Biochem J 342(Pt 2):281-286.
    • (1999) Biochem J , vol.342 , Issue.PART 2 , pp. 281-286
    • Belting, M.1    Petersson, P.2
  • 75
    • 0028430957 scopus 로고
    • Folate receptor mediated DNA delivery into tumor cells: Potosomal disruption results in enhanced gene expression
    • Gottschalk S, Cristiano RJ, Smith LC, Woo SL. 1994. Folate receptor mediated DNA delivery into tumor cells: potosomal disruption results in enhanced gene expression. Gene Ther 1(3):185-191.
    • (1994) Gene Ther , vol.1 , Issue.3 , pp. 185-191
    • Gottschalk, S.1    Cristiano, R.J.2    Smith, L.C.3    Woo, S.L.4
  • 76
    • 0033804202 scopus 로고    scopus 로고
    • Poly (DMAEMA-NVP)-b-PEG-galactose as gene delivery vector for hepatocytes
    • Lim DW, Yeom YI, Park TG. 2000. Poly (DMAEMA-NVP)-b-PEG-galactose as gene delivery vector for hepatocytes. Bioconjug Chem 11(5):688-695.
    • (2000) Bioconjug Chem , vol.11 , Issue.5 , pp. 688-695
    • Lim, D.W.1    Yeom, Y.I.2    Park, T.G.3
  • 78
    • 0032472885 scopus 로고    scopus 로고
    • Receptor-mediated delivery of foreign genes to hepatocytes
    • Wu CH, Wu GY. 1998. Receptor-mediated delivery of foreign genes to hepatocytes. Adv Drug Deliv Rev 29(3):243-248.
    • (1998) Adv Drug Deliv Rev , vol.29 , Issue.3 , pp. 243-248
    • Wu, C.H.1    Wu, G.Y.2
  • 79
    • 0027233696 scopus 로고
    • Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. Prolonged persistence in cytoplasmic vesicles after partial hepatectomy
    • Chowdhury NR, Wu CH, Wu GY, Yerneni PC, Bommineni VR, Chowdhury JR. 1993. Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. Prolonged persistence in cytoplasmic vesicles after partial hepatectomy. J Biol Chem 268(15):11265-11271.
    • (1993) J Biol Chem , vol.268 , Issue.15 , pp. 11265-11271
    • Chowdhury, N.R.1    Wu, C.H.2    Wu, G.Y.3    Yerneni, P.C.4    Bommineni, V.R.5    Chowdhury, J.R.6
  • 80
    • 0026315433 scopus 로고
    • Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats
    • Wu GY, Wilson JM, Shalaby F, Grossman M, Shafritz DA, Wu CH. 1991. Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats. J Biol Chem 266(22):14338-14342.
    • (1991) J Biol Chem , vol.266 , Issue.22 , pp. 14338-14342
    • Wu, G.Y.1    Wilson, J.M.2    Shalaby, F.3    Grossman, M.4    Shafritz, D.A.5    Wu, C.H.6
  • 82
    • 0032806151 scopus 로고    scopus 로고
    • Coupling of a targeting peptide to plasmid DNA by covalent triple helix formation
    • Neves C, Byk G, Scherman D, Wils P. 1999. Coupling of a targeting peptide to plasmid DNA by covalent triple helix formation. FEBS Lett 453(1-2):41-45.
    • (1999) FEBS Lett , vol.453 , Issue.1-2 , pp. 41-45
    • Neves, C.1    Byk, G.2    Scherman, D.3    Wils, P.4
  • 83
    • 0032841708 scopus 로고    scopus 로고
    • Polyethylene glycolenhances lipoplex-cell association and lipofection
    • Ross PC, Hui SW. 1999. Polyethylene glycolenhances lipoplex-cell association and lipofection. Biochim Biophys Acta 1421(2):273-283.
    • (1999) Biochim Biophys Acta , vol.1421 , Issue.2 , pp. 273-283
    • Ross, P.C.1    Hui, S.W.2
  • 84
    • 0033898807 scopus 로고    scopus 로고
    • Enhancement of transfection by physical concentration of DNA at the cell surface
    • Luo D, Saltzman WM. 2000. Enhancement of transfection by physical concentration of DNA at the cell surface. Nat Biotechnol 18(8):893-895.
    • (2000) Nat Biotechnol , vol.18 , Issue.8 , pp. 893-895
    • Luo, D.1    Saltzman, W.M.2
  • 85
    • 0030462391 scopus 로고    scopus 로고
    • Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold
    • Boussif O, Zanta MA, Behr JP. 1996. Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold. Gene Ther 3(12):1074-1080.
    • (1996) Gene Ther , vol.3 , Issue.12 , pp. 1074-1080
    • Boussif, O.1    Zanta, M.A.2    Behr, J.P.3
  • 86
    • 0034611710 scopus 로고    scopus 로고
    • Transfection using synthetic peptides: Comparison of three DNA-compacting peptides and effect of centrifugation
    • Vaysse L, Arveiler B. 2000. Transfection using synthetic peptides: comparison of three DNA-compacting peptides and effect of centrifugation. Biochim Biophys Acta 1474(2):244-250.
    • (2000) Biochim Biophys Acta , vol.1474 , Issue.2 , pp. 244-250
    • Vaysse, L.1    Arveiler, B.2
  • 88
    • 0020352106 scopus 로고
    • Adsorptive pinocytosis of polycationic copolymers of vinylpyrrolidone with vinylamine by rat yolk sac and rat peritoneal macrophage
    • Pratten MK, Cable HC, Ringsdorf H, Lloyd JB. 1982. Adsorptive pinocytosis of polycationic copolymers of vinylpyrrolidone with vinylamine by rat yolk sac and rat peritoneal macrophage. Biochim Biophys Acta 719(3):424-430.
    • (1982) Biochim Biophys Acta , vol.719 , Issue.3 , pp. 424-430
    • Pratten, M.K.1    Cable, H.C.2    Ringsdorf, H.3    Lloyd, J.B.4
  • 89
    • 0022803431 scopus 로고
    • Charge effect on binding, uptake and transport of ferritin through fenestrated endothelium
    • Ghinea N, Hasu M. 1986. Charge effect on binding, uptake and transport of ferritin through fenestrated endothelium. J Submicrosc Cytol 18(4):647-659.
    • (1986) J Submicrosc Cytol , vol.18 , Issue.4 , pp. 647-659
    • Ghinea, N.1    Hasu, M.2
  • 90
    • 0020794744 scopus 로고
    • Endocytosis, intracellular transport, and turnover of anionic and cationic proteins in cultured mouse peritoneal macrophages
    • Stenseth K, Hedin U, Thyberg J. 1983. Endocytosis, intracellular transport, and turnover of anionic and cationic proteins in cultured mouse peritoneal macrophages. Eur J Cell Biol 31(1):15-25.
    • (1983) Eur J Cell Biol , vol.31 , Issue.1 , pp. 15-25
    • Stenseth, K.1    Hedin, U.2    Thyberg, J.3
  • 91
    • 0037124051 scopus 로고    scopus 로고
    • Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis
    • Zuhorn IS, Kalicharan R, Hoekstra D. 2002. Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis. J Biol Chem 277(20):18021-18028.
    • (2002) J Biol Chem , vol.277 , Issue.20 , pp. 18021-18028
    • Zuhorn, I.S.1    Kalicharan, R.2    Hoekstra, D.3
  • 92
    • 0030071910 scopus 로고    scopus 로고
    • Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes
    • Friend DS, Papahadjopoulos D, Debs RJ. 1996. Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes. Biochim Biophys Acta 1278(1):41-50.
    • (1996) Biochim Biophys Acta , vol.1278 , Issue.1 , pp. 41-50
    • Friend, D.S.1    Papahadjopoulos, D.2    Debs, R.J.3
  • 93
    • 0031013538 scopus 로고    scopus 로고
    • Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells
    • Matsui H, Johnson LG, Randell SH, Boucher RC. 1997. Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells. J Biol Chem 272(2):1117-1126.
    • (1997) J Biol Chem , vol.272 , Issue.2 , pp. 1117-1126
    • Matsui, H.1    Johnson, L.G.2    Randell, S.H.3    Boucher, R.C.4
  • 96
    • 0037050752 scopus 로고    scopus 로고
    • Characterization of a novel pH-sensitive peptide that enhances drug release from folate-targeted liposomes at endosomal pHs
    • Turk MJ, Reddy JA, Chmielewski JA, Low PS. 2002. Characterization of a novel pH-sensitive peptide that enhances drug release from folate-targeted liposomes at endosomal pHs. Biochim Biophys Acta 1559(1):56-68.
    • (2002) Biochim Biophys Acta , vol.1559 , Issue.1 , pp. 56-68
    • Turk, M.J.1    Reddy, J.A.2    Chmielewski, J.A.3    Low, P.S.4
  • 97
    • 0027218124 scopus 로고
    • Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria
    • Francis CL, Ryan TA, Jones BD, Smith SJ, Falkow S. 1993. Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria. Nature 364(6438):639-642.
    • (1993) Nature , vol.364 , Issue.6438 , pp. 639-642
    • Francis, C.L.1    Ryan, T.A.2    Jones, B.D.3    Smith, S.J.4    Falkow, S.5
  • 98
    • 0034794184 scopus 로고    scopus 로고
    • The interface of receptor trafficking and signalling
    • Clague MJ, Urbe S. 2001. The interface of receptor trafficking and signalling. J Cell Sci 114(Pt 17):3075-3081.
    • (2001) J Cell Sci , vol.114 , Issue.PART 17 , pp. 3075-3081
    • Clague, M.J.1    Urbe, S.2
  • 99
    • 0029983628 scopus 로고    scopus 로고
    • The role of the adenovirus protease on virus entry into cells
    • Greber UF, Webster P, Weber J, Helenius A. 1996. The role of the adenovirus protease on virus entry into cells. EMBO J 15(8):1766-1777.
    • (1996) EMBO J , vol.15 , Issue.8 , pp. 1766-1777
    • Greber, U.F.1    Webster, P.2    Weber, J.3    Helenius, A.4
  • 100
    • 0029949266 scopus 로고    scopus 로고
    • Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
    • Xu Y, Szoka FC, Jr. 1996. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 35(18):5616-5623.
    • (1996) Biochemistry , vol.35 , Issue.18 , pp. 5616-5623
    • Xu, Y.1    Szoka F.C., Jr.2
  • 101
    • 0344707080 scopus 로고    scopus 로고
    • The role of helper lipids in cationic liposome-mediated gene transfer
    • Hui SW, Langner M, Zhao YL, Ross P, Hurley E, Chan K. 1996. The role of helper lipids in cationic liposome-mediated gene transfer. Biophys J 71(2):590-599.
    • (1996) Biophys J , vol.71 , Issue.2 , pp. 590-599
    • Hui, S.W.1    Langner, M.2    Zhao, Y.L.3    Ross, P.4    Hurley, E.5    Chan, K.6
  • 102
    • 0029067792 scopus 로고
    • The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer
    • Farhood H, Serbina N, Huang L. 1995. The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta 1235(2):289-295.
    • (1995) Biochim Biophys Acta , vol.1235 , Issue.2 , pp. 289-295
    • Farhood, H.1    Serbina, N.2    Huang, L.3
  • 103
    • 0034882516 scopus 로고    scopus 로고
    • On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids
    • Hafez IM, Maurer N, Cullis PR. 2001. On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids. Gene Ther 8(15):1188-1196.
    • (2001) Gene Ther , vol.8 , Issue.15 , pp. 1188-1196
    • Hafez, I.M.1    Maurer, N.2    Cullis, P.R.3
  • 105
    • 0033856291 scopus 로고    scopus 로고
    • Surface charge markedly attenuates the nonlamellar phase-forming propensities of lipid bilayer membranes: Calorimetric and (31)P-nuclear magnetic resonance studies of mixtures of cationic, anionic, and zwitterionic lipids
    • Lewis RN, McElhaney RN. 2000. Surface charge markedly attenuates the nonlamellar phase-forming propensities of lipid bilayer membranes: Calorimetric and (31)P-nuclear magnetic resonance studies of mixtures of cationic, anionic, and zwitterionic lipids. Biophys J 79(3):1455-1464.
    • (2000) Biophys J , vol.79 , Issue.3 , pp. 1455-1464
    • Lewis, R.N.1    McElhaney, R.N.2
  • 107
    • 0031551011 scopus 로고    scopus 로고
    • Gene transfer mediated by cationic lipids: Lack of a correlation between lipid mixing and transfection
    • Stegmann T, Legendre JY. 1997. Gene transfer mediated by cationic lipids: Lack of a correlation between lipid mixing and transfection. Biochim Biophys Acta 1325(1):71-79.
    • (1997) Biochim Biophys Acta , vol.1325 , Issue.1 , pp. 71-79
    • Stegmann, T.1    Legendre, J.Y.2
  • 108
    • 0035286969 scopus 로고    scopus 로고
    • Polyethylenimine-mediated gene delivery: A mechanistic study
    • Kichler A, Leborgne C, Coeytaux E, Danos O. 2001. Polyethylenimine-mediated gene delivery: A mechanistic study. J Gene Med 3(2):135-144.
    • (2001) J Gene Med , vol.3 , Issue.2 , pp. 135-144
    • Kichler, A.1    Leborgne, C.2    Coeytaux, E.3    Danos, O.4
  • 109
    • 0024269716 scopus 로고
    • Endosomes differ from plasma membranes in the phospholipid molecular species composition
    • Urade R, Hayashi Y, Kito M. 1988. Endosomes differ from plasma membranes in the phospholipid molecular species composition. Biochim Biophys Acta 946(1):151-163.
    • (1988) Biochim Biophys Acta , vol.946 , Issue.1 , pp. 151-163
    • Urade, R.1    Hayashi, Y.2    Kito, M.3
  • 110
    • 0031026824 scopus 로고    scopus 로고
    • Membrane fusion with cationic liposomes: Effects of target membrane lipid composition
    • Bailey AL, Cullis PR. 1997. Membrane fusion with cationic liposomes: Effects of target membrane lipid composition. Biochemistry 36(7):1628-1634.
    • (1997) Biochemistry , vol.36 , Issue.7 , pp. 1628-1634
    • Bailey, A.L.1    Cullis, P.R.2
  • 111
    • 0033651746 scopus 로고    scopus 로고
    • High-generation polycationic dendrimers are unusually effective at disrupting anionic vesicles: Membrane bending model
    • Zhang ZY, Smith BD. 2000. High-generation polycationic dendrimers are unusually effective at disrupting anionic vesicles: Membrane bending model. Bioconjug Chem 11(6):805-814.
    • (2000) Bioconjug Chem , vol.11 , Issue.6 , pp. 805-814
    • Zhang, Z.Y.1    Smith, B.D.2
  • 112
    • 0031782223 scopus 로고    scopus 로고
    • Effects of polyethyleneimine on endocytosis and lysosome stability
    • Klemm AR, Young D, Lloyd JB. 1998. Effects of polyethyleneimine on endocytosis and lysosome stability. Biochem Pharmacol 56(1):41-46.
    • (1998) Biochem Pharmacol , vol.56 , Issue.1 , pp. 41-46
    • Klemm, A.R.1    Young, D.2    Lloyd, J.B.3
  • 113
    • 0030817274 scopus 로고    scopus 로고
    • Polyethyleneimine is an effective permeabilizer of gram-negative bacteria
    • Helander IM, Alakomi HL, Latva-Kala K, Koski P. 1997. Polyethyleneimine is an effective permeabilizer of gram-negative bacteria. Microbiology 143(Pt 10):3193-3199.
    • (1997) Microbiology , vol.143 , Issue.PART 10 , pp. 3193-3199
    • Helander, I.M.1    Alakomi, H.L.2    Latva-Kala, K.3    Koski, P.4
  • 115
    • 0035024033 scopus 로고    scopus 로고
    • Regulation of organelle acidity
    • Grabe M, Oster G. 2001. Regulation of organelle acidity. J Gen Physiol 117(4):329-344.
    • (2001) J Gen Physiol , vol.117 , Issue.4 , pp. 329-344
    • Grabe, M.1    Oster, G.2
  • 117
    • 0002355789 scopus 로고
    • Acidification of endocytic vesicles and lysosomes
    • Pastan I, Willingham MC, editors. New York: Plenum Press
    • Maxfield FR. 1985. Acidification of endocytic vesicles and lysosomes. In: Pastan I, Willingham MC, editors. Endocytosis. New York: Plenum Press. pp 235-257.
    • (1985) Endocytosis , pp. 235-257
    • Maxfield, F.R.1
  • 118
    • 0028132679 scopus 로고
    • Ionization of poly(ethylenimine) and poly(allylamine) at various pH's
    • Suh J, Paik H-j, Hwang BK. 1994. Ionization of poly(ethylenimine) and poly(allylamine) at various pH's. Bioorg Chem 22:318-327.
    • (1994) Bioorg Chem , vol.22 , pp. 318-327
    • Suh, J.1    Paik, H.-J.2    Hwang, B.K.3
  • 119
    • 0034609633 scopus 로고    scopus 로고
    • Poly(ethylenimine)-mediated transfection: A new paradigm for gene delivery
    • Godbey WT, Barry MA, Saggau P, Wu KK, Mikos AG. 2000. Poly(ethylenimine)-mediated transfection: A new paradigm for gene delivery. J Biomed Mater Res 51(3):321-328.
    • (2000) J Biomed Mater Res , vol.51 , Issue.3 , pp. 321-328
    • Godbey, W.T.1    Barry, M.A.2    Saggau, P.3    Wu, K.K.4    Mikos, A.G.5
  • 120
    • 0035821383 scopus 로고    scopus 로고
    • Enhanced plasmid DNA transfection with lysosomotropic agents in cultured fibroblasts
    • Ciftci K, Levy RJ. 2001. Enhanced plasmid DNA transfection with lysosomotropic agents in cultured fibroblasts. Int J Pharm 218(1-2):81-92.
    • (2001) Int J Pharm , vol.218 , Issue.1-2 , pp. 81-92
    • Ciftci, K.1    Levy, R.J.2
  • 121
    • 0029984095 scopus 로고    scopus 로고
    • Glycerol enhancement of ligand-polylysine/DNA transfection
    • Zauner W, Kichler A, Schmidt W, Sinski A, Wagner E. 1996. Glycerol enhancement of ligand-polylysine/DNA transfection. Biotechniques 20(5):905-913.
    • (1996) Biotechniques , vol.20 , Issue.5 , pp. 905-913
    • Zauner, W.1    Kichler, A.2    Schmidt, W.3    Sinski, A.4    Wagner, E.5
  • 122
    • 0031562675 scopus 로고    scopus 로고
    • Glycerol and polylysine synergize in their ability to rupture vesicular membranes: A mechanism for increased transferrin-polylysine-mediated gene transfer
    • Zauner W, Kichler A, Schmidt W, Mechtler K, Wagner E. 1997. Glycerol and polylysine synergize in their ability to rupture vesicular membranes: A mechanism for increased transferrin-polylysine-mediated gene transfer. Exp Cell Res 232(1):137-145.
    • (1997) Exp Cell Res , vol.232 , Issue.1 , pp. 137-145
    • Zauner, W.1    Kichler, A.2    Schmidt, W.3    Mechtler, K.4    Wagner, E.5
  • 123
    • 0032580528 scopus 로고    scopus 로고
    • Effects of membrane-active agents in gene delivery
    • Wagner E. 1998. Effects of membrane-active agents in gene delivery. J Controlled Release 53(1-3):155-158.
    • (1998) J Controlled Release , vol.53 , Issue.1-3 , pp. 155-158
    • Wagner, E.1
  • 124
    • 0036230134 scopus 로고    scopus 로고
    • Role of intracellular cationic liposome-DNA complex dissociation in transfection mediated by cationic lipids
    • Cornelis S, Vandenbranden M, Ruysschaert JM, Elouahabi A. 2002. Role of intracellular cationic liposome-DNA complex dissociation in transfection mediated by cationic lipids. DNA Cell Biol 21(2):91-97.
    • (2002) DNA Cell Biol , vol.21 , Issue.2 , pp. 91-97
    • Cornelis, S.1    Vandenbranden, M.2    Ruysschaert, J.M.3    Elouahabi, A.4
  • 125
  • 129
    • 0032571392 scopus 로고    scopus 로고
    • Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells
    • Pollard H, Remy JS, Loussouarn G, Demolombe S, Behr JP, Escande D. 1998. Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J Biol Chem 273(13):7507-7511.
    • (1998) J Biol Chem , vol.273 , Issue.13 , pp. 7507-7511
    • Pollard, H.1    Remy, J.S.2    Loussouarn, G.3    Demolombe, S.4    Behr, J.P.5    Escande, D.6
  • 130
    • 0031079644 scopus 로고    scopus 로고
    • Import of plasmid DNA into the nucleus is sequence specific
    • Dean DA. 1997. Import of plasmid DNA into the nucleus is sequence specific. Exp Cell Res 230(2):293-302.
    • (1997) Exp Cell Res , vol.230 , Issue.2 , pp. 293-302
    • Dean, D.A.1
  • 131
    • 12244271784 scopus 로고    scopus 로고
    • The transport of molecules into and out of the nucleus
    • Alberts B, Bray D, Lewis J, Raff M, Roberts K, Watson JD, editors. New York: Garland Publishing
    • Walter P. 1999. The transport of molecules into and out of the nucleus. In: Alberts B, Bray D, Lewis J, Raff M, Roberts K, Watson JD, editors. Molecular biology of the cell New York: Garland Publishing. pp 561-568.
    • (1999) Molecular Biology of the Cell , pp. 561-568
    • Walter, P.1
  • 132
    • 0034022647 scopus 로고    scopus 로고
    • The nuclear pore complex: A protein machine bridging the nucleus and cytoplasm
    • Ryan KJ, Wente SR. 2000. The nuclear pore complex: A protein machine bridging the nucleus and cytoplasm. Curr Opin Cell Biol 12(3):361-371.
    • (2000) Curr Opin Cell Biol , vol.12 , Issue.3 , pp. 361-371
    • Ryan, K.J.1    Wente, S.R.2
  • 133
    • 0031707505 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: The soluble phase
    • Mattaj IW, Englmeier L. 1998. Nucleocytoplasmic transport: The soluble phase. Annu Rev Biochem 67:265-306.
    • (1998) Annu Rev Biochem , vol.67 , pp. 265-306
    • Mattaj, I.W.1    Englmeier, L.2
  • 135
    • 0028223310 scopus 로고
    • Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake
    • Perales JC, Ferkol T, Beegen H, Ratnoff OD, Hanson RW. 1994. Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake. Proc Natl Acad Sci USA 91(9):4086-4090.
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.9 , pp. 4086-4090
    • Perales, J.C.1    Ferkol, T.2    Beegen, H.3    Ratnoff, O.D.4    Hanson, R.W.5
  • 136
    • 0033047861 scopus 로고    scopus 로고
    • Cell-specific nuclear import of plasmid DNA
    • Vacik J, Dean BS, Zimmer WE, Dean DA. 1999. Cell-specific nuclear import of plasmid DNA. Gene Ther 6(6):1006-1014.
    • (1999) Gene Ther , vol.6 , Issue.6 , pp. 1006-1014
    • Vacik, J.1    Dean, B.S.2    Zimmer, W.E.3    Dean, D.A.4
  • 137
    • 0033524453 scopus 로고    scopus 로고
    • Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus
    • Zanta MA, Belguise-Valladier P, Behr JP. 1999. Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci USA 96(1):91-96.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.1 , pp. 91-96
    • Zanta, M.A.1    Belguise-Valladier, P.2    Behr, J.P.3
  • 138
    • 0032859928 scopus 로고    scopus 로고
    • A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA
    • Branden LJ, Mohamed AJ, Smith CI. 1999. A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA. Nat Biotechnol 17(8):784-787.
    • (1999) Nat Biotechnol , vol.17 , Issue.8 , pp. 784-787
    • Branden, L.J.1    Mohamed, A.J.2    Smith, C.I.3
  • 139
    • 0030458784 scopus 로고    scopus 로고
    • Efficacy of a peptide-based gene delivery system depends on mitotic activity
    • Wilke M, Fortunati E, van den Broek M, Hoogeveen AT, Scholte BJ. 1996. Efficacy of a peptide-based gene delivery system depends on mitotic activity. Gene Ther 3(12):1133-1142.
    • (1996) Gene Ther , vol.3 , Issue.12 , pp. 1133-1142
    • Wilke, M.1    Fortunati, E.2    Van den Broek, M.3    Hoogeveen, A.T.4    Scholte, B.J.5
  • 140
    • 0033553126 scopus 로고    scopus 로고
    • Mitosis enhances transgene expression of plasmid delivered by cationic liposomes
    • Tseng WC, Haselton FR, Giorgio TD. 1999. Mitosis enhances transgene expression of plasmid delivered by cationic liposomes. Biochim Biophys Acta 1445(1):53-64.
    • (1999) Biochim Biophys Acta , vol.1445 , Issue.1 , pp. 53-64
    • Tseng, W.C.1    Haselton, F.R.2    Giorgio, T.D.3
  • 141
    • 0033038501 scopus 로고    scopus 로고
    • Cationic lipid-mediated transfection of cells in culture requires mitotic activity
    • Mortimer I, Tam P, MacLachlan I, Graham RW, Saravolac EG, Joshi PB. 1999. Cationic lipid-mediated transfection of cells in culture requires mitotic activity. Gene Ther 6(3):403-411.
    • (1999) Gene Ther , vol.6 , Issue.3 , pp. 403-411
    • Mortimer, I.1    Tam, P.2    MacLachlan, I.3    Graham, R.W.4    Saravolac, E.G.5    Joshi, P.B.6
  • 142
    • 0030864266 scopus 로고    scopus 로고
    • A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia
    • Fasbender A, Zabner J, Zeiher BG, Welsh MJ. 1997. A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia. Gene Ther 4(11):1173-1180.
    • (1997) Gene Ther , vol.4 , Issue.11 , pp. 1173-1180
    • Fasbender, A.1    Zabner, J.2    Zeiher, B.G.3    Welsh, M.J.4
  • 143
    • 0034059514 scopus 로고    scopus 로고
    • Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus
    • Brunner S, Sauer T, Carotta S, Cotten M, Saltik M, Wagner E. 2000. Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus. Gene Ther 7(5):401-407.
    • (2000) Gene Ther , vol.7 , Issue.5 , pp. 401-407
    • Brunner, S.1    Sauer, T.2    Carotta, S.3    Cotten, M.4    Saltik, M.5    Wagner, E.6
  • 144
    • 0033230452 scopus 로고    scopus 로고
    • Subcellular trafficking of the cytoplasmic expression system
    • Brisson M, Tseng WC, Almonte C, Watkins S, Huang L. 1999. Subcellular trafficking of the cytoplasmic expression system. Hum Gene Ther 10(16):2601-2613.
    • (1999) Hum Gene Ther , vol.10 , Issue.16 , pp. 2601-2613
    • Brisson, M.1    Tseng, W.C.2    Almonte, C.3    Watkins, S.4    Huang, L.5
  • 148
    • 0031750860 scopus 로고    scopus 로고
    • In vitro myotoxicity of selected cationic macromolecules used in non-viral gene delivery
    • Brazeau GA, Attia S, Poxon S, Hughes JA. 1998. In vitro myotoxicity of selected cationic macromolecules used in non-viral gene delivery. Pharm Res 15(5):680-684.
    • (1998) Pharm Res , vol.15 , Issue.5 , pp. 680-684
    • Brazeau, G.A.1    Attia, S.2    Poxon, S.3    Hughes, J.A.4
  • 149
    • 0031739312 scopus 로고    scopus 로고
    • Enhanced gene expression in mouse lung by prolonging the retention time of intravenously injected plasmid DNA
    • Song YK, Liu F, Liu D. 1998. Enhanced gene expression in mouse lung by prolonging the retention time of intravenously injected plasmid DNA. Gene Ther 5(11):1531-1537.
    • (1998) Gene Ther , vol.5 , Issue.11 , pp. 1531-1537
    • Song, Y.K.1    Liu, F.2    Liu, D.3
  • 150
    • 0034991899 scopus 로고    scopus 로고
    • Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity
    • Tan Y, Liu F, Li Z, Li S, Huang L. 2001. Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity. Mol Ther 3(5 Pt 1): 673-682.
    • (2001) Mol Ther , vol.3 , Issue.5 PART 1 , pp. 673-682
    • Tan, Y.1    Liu, F.2    Li, Z.3    Li, S.4    Huang, L.5
  • 151
    • 0036207501 scopus 로고    scopus 로고
    • Overcoming the inflammatory toxicity of cationic gene vectors
    • Tan Y, Huang L. 2002. Overcoming the inflammatory toxicity of cationic gene vectors. J Drug Target 10(2):153-160.
    • (2002) J Drug Target , vol.10 , Issue.2 , pp. 153-160
    • Tan, Y.1    Huang, L.2
  • 152
    • 0031436820 scopus 로고    scopus 로고
    • A new DNA vehicle for nonviral gene delivery: Supercoiled minicircle
    • Darquet AM, Cameron B, Wils P, Scherman D, Crouzet J. 1997. A new DNA vehicle for nonviral gene delivery: Supercoiled minicircle. Gene Ther 4(12):1341-1349.
    • (1997) Gene Ther , vol.4 , Issue.12 , pp. 1341-1349
    • Darquet, A.M.1    Cameron, B.2    Wils, P.3    Scherman, D.4    Crouzet, J.5
  • 153
    • 0035132414 scopus 로고    scopus 로고
    • Efficient in vivo gene transfer by PCR amplified fragment with reduced inflammatory activity
    • Hofman CR, Dileo JP, Li Z, Li S, Huang L. 2001. Efficient in vivo gene transfer by PCR amplified fragment with reduced inflammatory activity. Gene Ther 8(1):71-74.
    • (2001) Gene Ther , vol.8 , Issue.1 , pp. 71-74
    • Hofman, C.R.1    Dileo, J.P.2    Li, Z.3    Li, S.4    Huang, L.5
  • 154
    • 0037005729 scopus 로고    scopus 로고
    • Characterization of the inhibitory effect of PEG-lipid conjugates on the intracellular delivery of plasmid and antisense DNA mediated by cationic lipid liposomes
    • Song LY, Ahkong QF, Rong Q, Wang Z, Ansell S, Hope MJ, Mui B. 2002. Characterization of the inhibitory effect of PEG-lipid conjugates on the intracellular delivery of plasmid and antisense DNA mediated by cationic lipid liposomes. Biochim Biophys Acta 1558(1):1-13.
    • (2002) Biochim Biophys Acta , vol.1558 , Issue.1 , pp. 1-13
    • Song, L.Y.1    Ahkong, Q.F.2    Rong, Q.3    Wang, Z.4    Ansell, S.5    Hope, M.J.6    Mui, B.7


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