메뉴 건너뛰기




Volumn 8, Issue 1, 2001, Pages 71-74

Efficient in vivo gene transfer by PCR amplified fragment with reduced inflammatory activity

Author keywords

Cytokine; Gene therapy; Inflammation; PCR

Indexed keywords

DNA FRAGMENT; INTERLEUKIN 12; LIPID; LUCIFERASE; PLASMID DNA; SYNTHETIC DNA; TUMOR NECROSIS FACTOR ALPHA; VIRUS VECTOR;

EID: 0035132414     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301373     Document Type: Article
Times cited : (62)

References (35)
  • 6
    • 0032599950 scopus 로고    scopus 로고
    • Direct immunologic activities of CpG DNA and implications for gene therapy
    • (1999) J Gene Med , vol.1 , pp. 56-63
    • Krieg, A.M.1
  • 7
    • 0033065988 scopus 로고    scopus 로고
    • The influence of base sequence on the immunostimulatory properties of DNA
    • (1999) Immunol Res , vol.19 , pp. 35-46
    • Pisetsky, D.S.1
  • 8
    • 0030205135 scopus 로고    scopus 로고
    • An innate immune defence mechanism based on the recognition of CpG motifs in microbial DNA
    • (1996) J Lab Clin Med , vol.128 , pp. 128-133
    • Krieg, A.M.1
  • 9
    • 0022540321 scopus 로고
    • CpG rich islands and the function of DNA methylation
    • (London)
    • (1986) Nature , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 10
    • 0028931102 scopus 로고
    • CpG motifs in bacterial DNA trigger direct B cell activation
    • (1995) Nature , vol.374 , pp. 546-549
    • Krieg, A.M.1
  • 12
    • 0029984358 scopus 로고    scopus 로고
    • CpG motifs present in bacterial DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon-γ
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2879-2883
    • Klinman, D.M.1
  • 13
    • 0030816325 scopus 로고    scopus 로고
    • Macrophage sense pathogens via DNA motifs: Induction of tumor necrosis factor-α mediated shock
    • (1997) Eur J Immunol , vol.27 , pp. 1671-1679
    • Sparwasser, T.1
  • 16
    • 0023009932 scopus 로고
    • In vivo anti-tumour activity recombinant human and murine TNF, alone and in combination with murine IFN-gamma, on a syngeneic murine melanoma
    • (1986) Int J Cancer , vol.38 , pp. 763-769
    • Brouckaert, P.G.1
  • 17
    • 0031581174 scopus 로고    scopus 로고
    • Promoter attenuation in gene therapy: Interferongamma and tumor necrosis factor-alpha inhibit transgene expression
    • (1997) Hum Gene Ther , vol.8 , pp. 2019-2029
    • Qin, L.1
  • 19
    • 0030866645 scopus 로고    scopus 로고
    • In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes
    • (1997) Gene Therapy , vol.4 , pp. 891-900
    • Li, S.1    Huang, L.2
  • 20
    • 0034149827 scopus 로고    scopus 로고
    • Reduced inflammatory response to plamid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs
    • (2000) Mol Ther , vol.1 , pp. 1-8
    • Yew, N.S.1
  • 21
    • 0033005285 scopus 로고    scopus 로고
    • Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors
    • (1999) Am J Physiol , vol.276 , pp. L796-L804
    • Li, S.1
  • 24
    • 0025231388 scopus 로고
    • Direct gene transfer into mouse muscle in vivo
    • (1990) Science , vol.247 , pp. 1465-1468
    • Wolff, J.A.1
  • 26
    • 0030709447 scopus 로고    scopus 로고
    • Expression of naked plasmid DNA injected into the afferent and efferent vessels of rodent and dog livers
    • (1997) Hum Gene Ther , vol.8 , pp. 1763-1772
    • Zhang, G.E.1
  • 28
    • 0029078539 scopus 로고
    • Intratracheal gene delivery to the mouse airway: Characterization of plasmid DNA expression and pharmacokinetics
    • (1995) Gene Therapy , vol.2 , pp. 450-460
    • Meyer, K.B.1
  • 34
    • 0020062818 scopus 로고
    • Transformation of hamster kidney cells by fragments of BK virus DNA
    • (1982) J Virol , vol.41 , pp. 319-325
    • Grossi, M.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.