Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 52, Issue 2, 2001, Pages 165-172

  Sakurai, Fuminori ^a   Nishioka, Tsuyoshi ^a   Yamashita, Fumiyoshi ^a   Takakura, Yoshinobu ^a   Hashida, Mitsuru ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Cationic liposome; Electrostatic interaction; Erythrocyte; Lipoplex; Lung perfusion; Serum

Indexed keywords

CATION; CHOLESTEROL; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; LIPOPLEX; LIPOSOME; N (1,2,3 DIOLEOYLOXYPROPYL) N,N,N TRIMETHYLAMMONIUM; PHOSPHORUS 32; PLASMA PROTEIN; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD; CAPILLARY ENDOTHELIUM; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BINDING; DRUG FORMULATION; ELECTRICITY; ERYTHROCYTE; LUNG CAPILLARY; LUNG PERFUSION; MALE; NONHUMAN; RAT; SERUM;

ANIMALS; BLOOD PROTEINS; CHOLESTEROL; ERYTHROCYTES; GLYCEROPHOSPHOLIPIDS; LIPOSOMES; LUNG; MALE; PERFUSION; PHOSPHATIDYLETHANOLAMINES; QUATERNARY AMMONIUM COMPOUNDS; RATS;

EID: 0034891884     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(01)00165-5     Document Type: Article

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