Systemic administration of LPD prepared with CpG oligonucleotides inhibits the growth of established pulmonary metastases by stimulating innate and acquired antitumor immune responses

Cancer Immunology, Immunotherapy

Volumn 50, Issue 10, 2001, Pages 503-514

  Whitmore, Mark M ^a,b,c   Li, Song ^a,b,c   Falo, Louis ^b,c   Huang, Leaf ^a,b,c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Antitumor; Cationic liposome; CpG DNA; Cytokine; Lipopolyplex; LPD; Oligodeoxynucleotide; Pulmonary metastasis

Indexed keywords

CD8 ANTIGEN; CHOLESTEROL; CYTOKINE; GAMMA INTERFERON; GLUCOSE; INTERLEUKIN 12; LIPOPOLYPLEX; LIPOSOME; OLIGODEOXYNUCLEOTIDE; PLASMID DNA; PROTAMINE SULFATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL DESTRUCTION; CANCER GROWTH; CANCER INHIBITION; CELLULAR IMMUNITY; CONTROLLED STUDY; CPG ISLAND; CYTOKINE PRODUCTION; DRUG EFFECT; GENE TARGETING; HUMAN; HUMAN CELL; INOCULATION; LUNG METASTASIS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TH1 CELL; TUMOR CELL LINE;

ANIMALS; CHOLESTEROL; CPG ISLANDS; CYTOTOXICITY, IMMUNOLOGIC; FATTY ACIDS, MONOUNSATURATED; LIPOSOMES; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; PLASMIDS; QUATERNARY AMMONIUM COMPOUNDS; TH1 CELLS;

EID: 0035668040     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620100227     Document Type: Article

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