Differential scanning calorimetric studies of the thermal stability of plasmid DNA complexed with cationic lipids and polymers

Journal of Pharmaceutical Sciences

Volumn 91, Issue 2, 2002, Pages 454-466

  Lobo, Brian A ^a   Rogers, Sheila A ^a   Choosakoonkriang, Sirirat ^a   Smith, Janet G ^b   Koe, Gary ^b   Middaugh, C Russell ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b Urigen Pharmaceuticals Inc   (United States)

Author keywords

Cationic lipid; Cationic polymer; Differential scanning calorimetry; DNA; Nonviral gene delivery; Supercoiling

Indexed keywords

1,2 DIOLEOYLTRIMETHYLAMMONIUM PROPANE CHLORIDE; 1,2 DISTEARYLTRIMETHYLAMMONIUM PROPANE CHLORIDE; AMMONIUM DERIVATIVE; CATION; CIRCULAR DNA; DIMETHYLDIOCTADECYLAMMONIUM BROMIDE; LIPID; PLASMID DNA; POLYARGININE; POLYETHYLENEIMINE; POLYLYSINE; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DIFFERENTIAL SCANNING CALORIMETRY; DNA BINDING; DNA STRUCTURE; DNA SUPERCOILING; GENETIC TRANSFECTION; MOLECULAR STABILITY; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; THERMODYNAMICS; THERMOSTABILITY;

EID: 0036174061     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10025     Document Type: Article

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