Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously

Journal of Immunology

Volumn 163, Issue 3, 1999, Pages 1552-1561

  Dow, Steven W ^a,b   Fradkin, Lee G ^d   Liggitt, Denny H ^c,d   Willson, Andy P ^a   Heath, Timothy D ^e   Potter, Terry A ^a,b  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d Megabios Corporation   (United States)

^e UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATIONIC LIPID DNA COMPLEX; CHOLESTEROL; CYTOKINE; DNA; LIPID; TRIMETHYLAMMONIUM SALT DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; FEMALE; GENE TRANSFER; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CYTOTOXICITY, IMMUNOLOGIC; DNA, BACTERIAL; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; DRUG COMBINATIONS; FEMALE; IMMUNITY, NATURAL; INJECTIONS, INTRAVENOUS; INTERFERON TYPE II; KILLER CELLS, NATURAL; LIPOSOMES; LUNG NEOPLASMS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED ICR; MICE, KNOCKOUT; TUMOR CELLS, CULTURED;

EID: 0010276632     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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