An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery

Science

Volumn 281, Issue 5373, 1998, Pages 78-81

  Koltover, Ilya ^a   Salditt, Tim ^a,b   Rädler, Joachim O ^a,c   Safinya, Cyrus R ^a  

^a Santa Barbara   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATION; DNA; LIPOSOME;

ARTICLE; COMPLEX FORMATION; ENDOSOME; GENE TARGETING; GENETIC TRANSFECTION; LAMELLAR BODY; LIPID COMPOSITION; LIPID MONOLAYER; MAMMAL CELL; MICROSCOPY; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; RADIATION SCATTERING; X RAY DIFFRACTION;

BIREFRINGENCE; CATIONS; DNA; ENDOCYTOSIS; ENDOSOMES; FATTY ACIDS, MONOUNSATURATED; HEXANOLS; LIPID BILAYERS; LIPOSOMES; MEMBRANE FUSION; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; QUATERNARY AMMONIUM COMPOUNDS; TRANSFECTION; X-RAY DIFFRACTION;

MAMMALIA;

EID: 0032479572     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.281.5373.78     Document Type: Article

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32. We thank R. Bruinsma, A. Ben-Shaul, J. Israelachvili, P. Pincus, W. Gelbart, T. Lubensky, and N. Dan for discussions. Supported by grants from the UC-Biotechnology Research and Education Program (97-02), NSF (DMR-9624091), Petroleum Research Foundation (31352-AC7), and Los Alamos National Laboratory (STB/UC:96-108). T.S. and J.O.R. acknowledge a Nato postdoctoral scholarship distributed by the DAAD and a DFG (Ra 655/1-1). The Materials Research Laboratory at Santa Barbara is supported by NSF grant DMR-9632716. The Stanford Synchrotron Radiation Laboratory is supported by the U.S. Department of Energy.