Physiological and pathophysiological roles of ATP-sensitive K+ channels

Progress in Biophysics and Molecular Biology

Volumn 81, Issue 2, 2003, Pages 133-176

  Seino, Susumu ^a   Miki, Takashi ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ABCC9 PROTEIN, MOUSE; ADENOSINE TRIPHOSPHATE; DRUG RECEPTOR; INWARDLY RECTIFYING POTASSIUM CHANNEL; MIXED FUNCTION OXIDASE; POTASSIUM CHANNEL; SULFONYLUREA RECEPTOR;

ANIMAL; BIOLOGICAL MODEL; DIABETES MELLITUS; DISEASE MODEL; ELECTROPHYSIOLOGY; HUMAN; HYPERINSULINISM; METABOLISM; MOUSE; MOUSE MUTANT; MUTATION; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; REVIEW; TRANSGENIC MOUSE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; ELECTROPHYSIOLOGY; HUMANS; HYPERINSULINISM; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MIXED FUNCTION OXYGENASES; MODELS, BIOLOGICAL; MUTATION; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, DRUG;

MUS MUSCULUS;

EID: 0037306308     PISSN: 00796107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0079-6107(02)00053-6     Document Type: Review

References (263)

1. Aguilar-Bryan L., Bryan J. Molecular biology of adenosine triphosphate-sensitive potassium channels. Endocrinol. Rev. 20(2):1999;101-135.
2. Aguilar-Bryan L., Nichols C.G., Wechsler S.W., Clement J.P.t., Boyd 3rd A.E., Gonzalez G., Herrera-Sosa H., Nguy K., Bryan J., Nelson D.A. Cloning of the beta cell high-affinity sulfonylurea receptor. a regulator of insulin secretion Science. 268(5209):1995;423-426.
3. ATP channels. Physiol. Rev. 78(1):1998;227-245.
4. Aizawa T., Komatsu M., Asanuma N., Sato Y., Sharp G.W. Glucose action 'beyond ionic events' in the pancreatic beta cell. Trends Pharmacol. Sci. 19(12):1998;496-499.
5. ATP channel gene expression in rat hearts. J. Clin. Invest. 100(12):1997;3053-3059.
6. Allard B., Lazdunski M. Nucleotide diphosphates activate the ATP-sensitive potassium channel in mouse skeletal muscle. Pflugers Arch. 422(2):1992;185-192.
7. + channels in mammalian skeletal muscle cells. Eur. J. Pharmacol. 236(3):1993;419-426.
8. + channels Science. 247(4944):1990;852-854.
9. Arena J.P., Kass R.S. Enhancement of potassium-sensitive current in heart cells by pinacidil. Evidence for modulation of the ATP-sensitive potassium channel. Circ. Res. 65(2):1989;436-445.
10. Ashcroft F.M. Adenosine 5′-triphosphate-sensitive potassium channels. Annu. Rev. Neurosci. 11:1988;97-118.
11. Ashcroft F.M., Rorsman P. Electrophysiology of the pancreatic beta-cell. Prog. Biophys. Mol. Biol. 54(2):1989;87-143.
12. + channels. Trends Neurosci. 21(7):1998;288-294.
13. ATP channels J Diabetes Complications. 14(4):2000;192-196.
14. ATP channel openers. Trends Pharmacol. Sci. 21(11):2000;439-445.
15. Ashcroft F.M., Harrison D.E., Ashcroft S.J. Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells. Nature. 312(5993):1984;446-448.
16. ATP channel. J. Membr. Biol. 176(3):2000;187-206.
17. Ashcroft S.J., Ashcroft F.M. Properties and functions of ATP-sensitive K-channels. Cell Signal. 2(3):1990;197-214.
18. ATP channel. Diabetes. 48(6):1999;1341-1347.
19. Ashford M.L., Sturgess N.C., Trout N.J., Gardner N.J., Hales C.N. Adenosine-5′-triphosphate-sensitive ion channels in neonatal rat cultured central neurones. Pflugers Arch. 412(3):1988;297-304.
20. + channels. Pflugers Arch. 415(4):1990;479-483.
21. + channels. Br. J. Pharmacol. 101(3):1990;531-540.
22. ATP channels. Annu. Rev. Physiol. 60:1998;667-687.
23. ATP channels. functional identity with the native channels from the sarcolemma of human ventricular cells Circ. Res. 83(11):1998;1132-1143.
24. ATP channel isoforms. J. Biol. Chem. 274(17):1999;11587-11592.
25. + channel openers. J. Biol. Chem. 275(2):2000;717-720.
26. Bagdade J.D., Bierman E.L., Porte D. Jr. The significance of basal insulin levels in the evaluation of the insulin response to glucose in diabetic and nondiabetic subjects. J. Clin. Invest. 46(10):1967;1549-1557.
27. ATP channels of mammalian skeletal muscle. J. Membr. Biol. 155(3):1997;257-262.
28. ATP channels. Science. 282(5391):1998;1141-1144.
29. Bear C.E., Li C., Galley K., Wang Y., Garami E., Ramjeesingh M. Coupling of ATP hydrolysis with channel gating by purified, reconstituted CFTR. J. Bioenerg. Biomembr. 29(5):1997;465-473.
30. Beech D.J., Zhang H., Nakao K., Bolton T.B. K channel activation by nucleotide diphosphates and its inhibition by glibenclamide in vascular smooth muscle cells. Br. J. Pharmacol. 110(2):1993;573-582.
31. ATP channel. separate roles of KIR6.2 and SUR1 subunit phosphorylation EMBO J. 18(17):1999;4722-4732.
32. Belardinelli L., Linden J., Berne R.M. The cardiac effects of adenosine. Prog. Cardiovasc. Dis. 32(1):1989;73-97.
33. Beltrame J.F., Sasayama S., Maseri A. Racial heterogeneity in coronary artery vasomotor reactivity. differences between Japanese and Caucasian patients J. Am. Coll. Cardiol. 33(6):1999;1442-1452.
34. Bergen H.T., Monkman N., Mobbs C.V. Injection with gold thioglucose impairs sensitivity to glucose. evidence that glucose-responsive neurons are important for long-term regulation of body weight Brain Res. 734(1-2):1996;332-336.
35. + channels sensitive to antidiabetic sulfonylureas are present in adenohypophysis and are involved in growth hormone release. Proc. Natl. Acad. Sci. USA. 90(4):1993;1340-1344.
36. ATP channel complex Faseb J. 14(13):2000;1943-1952.
37. ATP channel openers, adenosine agonists and epileptic preconditioning are stress signals inducing hippocampal neuroprotection. Neuroscience. 100(3):2000;465-474.
38. Borg M.A., Borg W.P., Tamborlane W.V., Brines M.L., Shulman G.I., Sherwin R.S. Chronic hypoglycemia and diabetes impair counterregulation induced by localized 2-deoxy-glucose perfusion of the ventromedial hypothalamus in rats. Diabetes. 48(3):1999;584-587.
39. Borg W.P., Sherwin R.S., During M.J., Borg M.A., Shulman G.I. Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release. Diabetes. 44(2):1995;180-184.
40. Boyd 3rd A.E. Sulfonylurea receptors, ion channels, and fruit flies. Diabetes. 37(7):1988;847-850.
41. Bril A., Laville M.P., Gout B. Effects of glibenclamide on ventricular arrhythmias and cardiac function in ischaemia and reperfusion in isolated rat heart. Cardiovasc. Res. 26(11):1992;1069-1076.
42. Bruning J.C., Gautam D., Burks D.J., Gillette J., Schubert M., Orban P.C., Klein R., Krone W., Muller-Wieland D., Kahn C.R. Role of brain insulin receptor in control of body weight and reproduction. Science. 289(5487):2000;2122-2125.
43. 2+] in isolated rat skeletal muscle during fatigue and metabolic blockade. Exp. Physiol. 82(3):1997;469-483.
44. Campfield L.A., Smith F.J., Guisez Y., Devos R., Burn P. Recombinant mouse OB protein. evidence for a peripheral signal linking adiposity and central neural networks Science. 269(5223):1995;546-549.
45. ATP channels caused by a sulfonylurea receptor 1 mutation associated with persistent hyperinsulinemic hypoglycemia of infancy. Proc. Natl. Acad. Sci. USA. 98(5):2001;2882-2887.
46. Chen H., Charlat O., Tartaglia L.A., Woolf E.A., Weng X., Ellis S.J., Lakey N.D., Culpepper J., Moore K.J., Breitbart R.E., Duyk G.M., Tepper R.I., Morgenstern J.P. Evidence that the diabetes gene encodes the leptin receptor. identification of a mutation in the leptin receptor gene in db/db mice Cell. 84(3):1996;491-495.
47. ATP channels. Diabetes. 45(10):1996;1439-1445.
48. Chutkow W.A., Makielski J.C., Nelson D.J., Burant C.F., Fan Z. Alternative splicing of Sur2 Exon 17 regulates nucleotide sensitivity of the ATP-sensitive potassium channel. J. Biol. Chem. 274(19):1999;13656-13665.
49. ATP channels enhances insulin-stimulated glucose uptake in skeletal muscle. Proc. Natl. Acad. Sci. USA. 98(20):2001;11760-11764.
50. ATP channels. J. Clin. Invest. 110(2):2002;203-208.
51. ATP channel subunits. Neuron. 18(5):1997;827-838.
52. ATP channel Annu. Rev. Physiol. 62:2000;79-109.
53. Comtois A., Light P., Renaud J.M. Effect of tolbutamide on the rate of fatigue and recovery in frog sartorius muscle. J. Pharmacol. Exp. Ther. 274(3):1995;1061-1066.
54. Considine R.V., Sinha M.K., Heiman M.L., Kriauciunas A., Stephens T.W., Nyce M.R., Ohannesian J.P., Marco C.C., McKee L.J., Bauer T.L.et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N. Engl. J. Med. 334(5):1996;292-295.
55. Conti L.R., Radeke C.M., Shyng S.L., Vandenberg C.A. Transmembrane topology of the sulfonylurea receptor SUR1. J. Biol. Chem. 276(44):2001;41270-41278.
56. + channels in pancreatic B-cells. Nature. 311(5983):1984;271-273.
57. + channels in pancreatic beta-cells. Spare-channel hypothesis. Diabetes. 37(5):1988;495-498.
58. + channels by hypoxia in smooth muscle cells isolated from the pig coronary artery. J. Physiol. 483(Part 1):1995;29-39.
59. Daut J., Maier-Rudolph W., von Beckerath N., Mehrke G., Gunther K., Goedel-Meinen L. Hypoxic dilation of coronary arteries is mediated by ATP-sensitive potassium channels. Science. 247(4948):1990;1341-1344.
60. Davis N.W., Standen N.B., Stanfield P.R. ATP-dependent potassium channels of muscle cells. their properties, regulation, and possible functions J. Bioenerg. Biomembr. 23(4):1991;509-535.
61. De Sarro G., Meldrum B.S., Reavill C. Anticonvulsant action of 2-amino-7-phosphonoheptanoic acid in the substantia nigra. Eur. J. Pharmacol. 106(1):1984;175-179.
62. Depaulis A., Vergnes M., Marescaux C. Endogenous control of epilepsy. the nigral inhibitory system Prog. Neurobiol. 42(1):1994;33-52.
63. + channel openers. Mol. Pharmacol. 56(2):1999;308-315.
64. D'Hahan N., Moreau C., Prost A.L., Jacquet H., Alekseev A.E., Terzic A., Vivaudou M. Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP. Proc. Natl. Acad. Sci. USA. 96(21):1999;12162-12167.
65. Drain P., Li L., Wang J. KATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit. Proc. Natl. Acad. Sci. USA. 95(23):1998;13953-13958.
66. Dunn-Meynell A.A., Routh V.H., McArdle J.J., Levin B.E. Low-affinity sulfonylurea binding sites reside on neuronal cell bodies in the brain. Brain Res. 745(1-2):1997;1-9.
67. + channels in an insulin-secreting cell line. J. Membr. Biol. 99(3):1987;215-224.
68. Duty S., Allen D.G. The effects of glibenclamide on tetanic force and intracellular calcium in normal and fatigued mouse skeletal muscle. Exp. Physiol. 80(4):1995;529-541.
69. Edwards G., Weston A.H. The pharmacology of ATP-sensitive potassium channels. Annu. Rev. Pharmacol. Toxicol. 33:1993;597-637.
70. + channels in guinea-pig cardiac myocytes. Pflugers Arch. 414(6):1989;669-675.
71. Faivre J.F., Findlay I. Effects of tolbutamide, glibenclamide and diazoxide upon action potentials recorded from rat ventricular muscle. Biochim. Biophys. Acta. 984(1):1989;1-5.
72. Faivre J.F., Findlay I. Action potential duration and activation of ATP-sensitive potassium current in isolated guinea-pig ventricular myocytes. Biochim. Biophys. Acta. 1029(1):1990;167-172.
73. Fan Z., Makielski J.C. Anionic phospholipids activate ATP-sensitive potassium channels. J. Biol. Chem. 272(9):1997;5388-5395.
74. Feliciano L., Henning R.J. Coronary artery blood flow. physiologic and pathophysiologic regulation Clin. Cardiol. 22(12):1999;775-786.
75. + channels in cardiac muscle by the sulphonylurea drug glibenclamide. J. Pharmacol. Exp. Ther. 261(2):1992;540-545.
76. Findlay I. The ATP sensitive potassium channel of cardiac muscle and action potential shortening during metabolic stress. Cardiovasc. Res. 28(6):1994;760-761.
77. Foster C.D., Fujii K., Kingdon J., Brading A.F. The effect of cromakalim on the smooth muscle of the guinea-pig urinary bladder. Br. J. Pharmacol. 97(1):1989;281-291.
78. Fujimura N., Tanaka E., Yamamoto S., Shigemori M., Higashi H. Contribution of ATP-sensitive potassium channels to hypoxic hyperpolarization in rat hippocampal CA1 neurons in vitro. J. Neurophysiol. 77(1):1997;378-385.
79. + channel openers. Pharmacol. Ther. 85(1):2000;39-53.
80. Garlid K.D., Paucek P., Yarov-Yarovoy V., Sun X., Schindler P.A. The mitochondrial KATP channel as a receptor for potassium channel openers. J. Biol. Chem. 271(15):1996;8796-8799.
81. + channels. Possible mechanism of cardioprotection. Circ. Res. 81(6):1997;1072-1082.
82. Gasser R.N., Vaughan-Jones R.D. Mechanism of potassium efflux and action potential shortening during ischaemia in isolated mammalian cardiac muscle. J. Physiol. 431:1990;713-741.
83. ATP channels as effectors of human myocardial preconditioning. Cardiovasc. Res. 45(4):2000;934-940.
84. Glaser B., Chiu K.C., Anker R., Nestorowicz A., Landau H., Ben-Bassat H., Shlomai Z., Kaiser N., Thornton P.S., Stanley C.A.et al. Familial hyperinsulinism maps to chromosome 11p14-15.1, 30 cM centromeric to the insulin gene. Nat. Genet. 7(2):1994;185-188.
85. Glaser B., Kesavan P., Heyman M., Davis E., Cuesta A., Buchs A., Stanley C.A., Thornton P.S., Permutt M.A., Matschinsky F.M., Herold K.C. Familial hyperinsulinism caused by an activating glucokinase mutation. N. Engl. J. Med. 338(4):1998;226-230.
86. ATP channel deficiency affects resting tension, not contractile force, during fatigue in skeletal muscle. Am. J. Physiol. Cell Physiol. 279(5):2000;C1351-1358.
87. + channel during metabolic inhibition impairs muscle contractility. Am. J. Physiol. 272(6 Part 1):1997;C1936-1946.
88. ATP channels to gliclazide. Diabetologia. 42(7):1999;845-848.
89. ATP channel activation by Mg-ADP and diazoxide. EMBO J. 16(6):1997;1145-1152.
90. ATP channels Diabetes. 47(9):1998;1412-1418.
91. Gross G.J., Auchampach J.A. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs. Circ. Res. 70(2):1992;223-233.
92. Grover G.J., Sleph P.G., Dzwonczyk S. Role of myocardial ATP-sensitive potassium channels in mediating preconditioning in the dog heart and their possible interaction with adenosine A1-receptors. Circulation. 86(4):1992;1310-1316.
93. + channel current in atrial myocytes of guinea pig heart. Jpn. J. Pharmacol. 54(4):1990;473-477.
94. + channel gene (KIR6.2/BIR). a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians Diabetologia. 41(12):1998;1511-1515.
95. Hart L.M., de Knijff P., Dekker J.M., Stolk R.P., Nijpels G., van der Does F.E., Ruige J.B., Grobbee D.E., Heine R.J., Maassen J.A. Variants in the sulphonylurea receptor gene. association of the exon 16-3t variant with Type II diabetes mellitus in Dutch Caucasians Diabetologia. 42(5):1999;617-620.
96. + channels. Science. 258(5085):1992;1152-1155.
97. Henquin J.C. Triggering and amplifying pathways of regulation of insulin secretion by glucose. Diabetes. 49(11):2000;1751-1760.
98. Hernandez-Sanchez C., Basile A.S., Fedorova I., Arima H., Stannard B., Fernandez A.M., Ito Y., LeRoith D. Mice transgenically overexpressing sulfonylurea receptor 1 in forebrain resist seizure induction and excitotoxic neuron death. Proc. Natl. Acad. Sci. USA. 98(6):2001;3549-3554.
99. Hess E.J. Identification of the weaver mouse mutation. the end of the beginning Neuron. 16(6):1996;1073-1076.
100. + channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid beta-protein precursor genes and neuronal death in rat hippocampus. Proc. Natl. Acad. Sci. USA. 90(20):1993;9431-9435.
101. + channels in cerebral ischemic preconditioning. Proc. Natl. Acad. Sci. USA. 92(10):1995;4666-4670.
102. Hicks G.A., Hudson A.L., Henderson G. Localization of high affinity [3H]glibenclamide binding sites within the substantia nigra zona reticulata of the rat brain. Neuroscience. 61(2):1994;285-292.
103. Higgins C.F. ABC transporters. from microorganisms to man Annu. Rev. Cell Biol. 8:1992;67-113.
104. ATP potassium channels by PIP2. Science. 273(5277):1996;956-959.
105. Hunter M., Giebisch G. Calcium-activated K-channels of Amphiuma early distal tubule. inhibition by ATP Pflugers Arch. 412(3):1988;331-333.
106. Huopio H., Reimann F., Ashfield R., Komulainen J., Lenko H.L., Rahier J., Vauhkonen I., Kere J., Laakso M., Ashcroft F., Otonkoski T. Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1. J. Clin. Invest. 106(7):2000;897-906.
107. Iadarola M.J., Gale K. Substantia nigra. site of anticonvulsant activity mediated by gamma-aminobutyric acid Science. 218(4578):1982;1237-1240.
108. Inagaki N., Tsuura Y., Namba N., Masuda K., Gonoi T., Horie M., Seino Y., Mizuta M., Seino S. Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart. J. Biol. Chem. 270(11):1995;5691-5694.
109. ATP-1, gene (KCNJ8). Genomics. 30(1):1995;102-104.
110. KATP. an inward rectifier subunit plus the sulfonylurea receptor Science. 270(5239):1995;1166-1170.
111. + channels. Neuron. 16(5):1996;1011-1017.
112. + channel. FEBS Lett. 409(2):1997;232-236.
113. + channel in the mitochondrial inner membrane. Nature. 352(6332):1991;244-247.
114. Inoue H., Ferrer J., Welling C.M., Elbein S.C., Hoffman M., Mayorga R., Warren-Perry M., Zhang Y., Millns H., Turner R., Province M., Bryan J., Permutt M.A., Aguilar-Bryan L. Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians. Diabetes. 45(6):1996;825-831.
115. + channels, adenosine, and nitric oxide-mediated mechanisms account for coronary vasodilation during exercise. Circ. Res. 82(3):1998;346-359.
116. + channel. J. Biol. Chem. 271(40):1996;24321-24324.
117. + channel and linkage studies with NIDDM in Japanese. Diabetes. 45(2):1996;267-269.
118. Jahangir A., Terzic A., Shen W. Potassium channel openers. therapeutic potential in cardiology and medicine Expert Opin. Pharmacother. 2(12):2001;1995-2010.
119. Jan L.Y., Jan Y.N. Potassium channels and their evolving gates. Nature. 371(6493):1994;119-122.
120. + channels linked to the green fluorescent protein in human embryonic kidney cells (HEK 293). J. Physiol. 510(Part 2):1998;333-345.
121. + channel in the rabbit portal vein. J. Physiol. 444:1991;397-418.
122. ATP channels in pancreatic beta-cells causes persistent hyperinsulinemic hypoglycemia of infancy. Nat. Med. 2(12):1996;1344-1347.
123. Kassem S.A., Ariel I., Thornton P.S., Scheimberg I., Glaser B. Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy. Diabetes. 49(8):2000;1325-1333.
124. Kerr I.D., Sansom M.S. Cation selectivity in ion channels. Nature. 373(6510):1995;112.
125. Kinlay S., Libby P., Ganz P. Endothelial function and coronary artery disease. Curr. Opin. Lipidol. 12(4):2001;383-389.
126. Kleber A.G. ST-segment elevation in the electrocardiogram. a sign of myocardial ischemia Cardiovasc. Res. 45(1):2000;111-118.
127. Ko Y.H., Pedersen P.L. The first nucleotide binding fold of the cystic fibrosis transmembrane conductance regulator can function as an active ATPase. J. Biol. Chem. 270(38):1995;22093-22096.
128. + channel and rescue of weaver granule cells. Neuron. 16(5):1996;941-952.
129. Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. 402(6762):1999;656-660.
130. Kono Y., Horie M., Takano M., Otani H., Xie L.H., Akao M., Tsuji K., Sasayama S. The properties of the KIR6.1-6.2 tandem channel co-expressed with SUR2A. Pflugers Arch. 440(5):2000;692-698.
131. ATP channels. Functional coupling of KIR6.2 and SUR1 subunits. J. Gen. Physiol. 114(2):1999;203-213.
132. ATP channels induces profound neonatal diabetes. Cell. 100(6):2000;645-654.
133. ATP channels in transgenic mice. Circ. Res. 89(11):2001;1022-1029.
134. ATP channel opener diazoxide protects cardiac myocytes during metabolic inhibition without causing mitochondrial depolarization or flavoprotein oxidation. Br. J. Pharmacol. 134(3):2001;535-542.
135. Li C., Ramjeesingh M., Wang W., Garami E., Hewryk M., Lee D., Rommens J.M., Galley K., Bear C.E. ATPase activity of the cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 271(45):1996;28463-28468.
136. Li R.A., Leppo M., Miki T., Seino S., Marban E. Molecular basis of electrocardiographic ST-segment elevation. Circ. Res. 87(10):2000;837-839.
137. ATP channel activation during fatigue J. Physiol. 475(3):1994;495-507.
138. Lin Y.F., Jan Y.N., Jan L.Y. Regulation of ATP-sensitive potassium channel function by protein kinase A-mediated phosphorylation in transfected HEK293 cells. EMBO J. 19(5):2000;942-955.
139. Lindner T., Gragnoli C., Schulze J., Rietzsch H., Petzold C., Schroder H.E., Cox N.J., Bell G.I. The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 non-Hispanic white affected sibships. Diabetes. 46(7):1997;1227-1229.
140. ATP channels in dopaminergic midbrain neurons. EMBO J. 18(4):1999;833-846.
141. Liu Y., Sato T., O'Rourke B., Marban E. Mitochondrial ATP-dependent potassium channels. novel effectors of cardioprotection? Circulation. 97(24):1998;2463-2469.
142. Longmore J., Bray K.M., Weston A.H. The contribution of Rb-permeable potassium channels to the relaxant and membrane hyperpolarizing actions of cromakalim, RP49356 and diazoxide in bovine tracheal smooth muscle. Br. J. Pharmacol. 102(4):1991;979-985.
143. Markworth E., Schwanstecher C., Schwanstecher M. ATP4-mediates closure of pancreatic beta-cell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites. Diabetes. 49(9):2000;1413-1418.
144. Maseri A. Louis F. Bishop lecture. Role of coronary artery spasm in symptomatic and silent myocardial ischemia. J. Am. Coll. Cardiol. 9(2):1987;249-262.
145. Matar W., Nosek T.M., Wong D., Renaud J. Pinacidil suppresses contractility and preserves energy but glibenclamide has no effect during muscle fatigue. Am. J. Physiol. Cell Physiol. 278(2):2000;C404-416.
146. Matsuo M., Kioka N., Amachi T., Ueda K. ATP binding properties of the nucleotide-binding folds of SUR1. J. Biol. Chem. 274(52):1999;37479-37482.
147. Matsuo M., Trapp S., Tanizawa Y., Kioka N., Amachi T., Oka Y., Ashcroft F.M., Ueda K. Functional analysis of a mutant sulfonylurea receptor, SUR1-R1420C, that is responsible for persistent hyperinsulinemic hypoglycemia of infancy. J. Biol. Chem. 275(52):2000;41184-41191.
148. McPherson G.A., Angus J.A. Characterization of responses to cromakalim and pinacidil in smooth and cardiac muscle by use of selective antagonists. Br. J. Pharmacol. 100(2):1990;201-206.
149. Mikhailov M.V., Proks P., Ashcroft F.M., Ashcroft S.J. Expression of functionally active ATP-sensitive K-channels in insect cells using baculovirus. FEBS Lett. 429(3):1998;390-394.
150. ATP channel. Proc. Natl. Acad. Sci. USA. 94(22):1997;11969-11973.
151. ATP channel-deficient mice. Proc. Natl. Acad. Sci. USA. 95(18):1998;10402-10406.
152. + channels in the hypothalamus are essential for the maintenance of glucose homeostasis. Nat. Neurosci. 4(5):2001;507-512.
153. Miki T., Suzuki M., Shibasaki T., Uemura H., Sato T., Yamaguchi K., Koseki H., Iwanaga T., Nakaya H., Seino S. Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1. Nat. Med. 8(5):2002;466-472.
154. Miki T., Minami K., Zhang L., Morita M., Gonoi T., Shiuchi T., Minokoshi Y., Renaud J.M., Seino S. ATP-sensitive potassium channels participate in glucose uptake in skeletal muscle and adipose tissue. Am. J. Physiol. Endocrinol. Metab. 283(6):2002;E1178-E1184.
155. Minami T., Oomura Y., Sugimori M. Electrophysiological properties and glucose responsiveness of guinea-pig ventromedial hypothalamic neurones in vitro. J. Physiol. 380:1986;127-143.
156. Mizumura T., Nithipatikom K., Gross G.J. Bimakalim, an ATP-sensitive potassium channel opener, mimics the effects of ischemic preconditioning to reduce infarct size, adenosine release, and neutrophil function in dogs. Circulation. 92(5):1995;1236-1245.
157. Mombouli J.V., Vanhoutte P.M. Endothelial dysfunction. from physiology to therapy J. Mol. Cell. Cardiol. 31(1):1999;61-74.
158. ATP channel openers. EMBO J. 19(24):2000;6644-6651.
159. Mourre C., Ben Ari Y., Bernardi H., Fosset M., Lazdunski M. Antidiabetic sulfonylureas. localization of binding sites in the brain and effects on the hyperpolarization induced by anoxia in hippocampal slices Brain Res. 486(1):1989;159-164.
160. Muller E.E., Cocchi D., Forni A. A central site for the hyperglycemic action of 2-deoxy-D-glucose in mouse and rat. Life Sci. I. 10(18):1971;1057-1067.
161. + channel blockers on the action potential shortening in hypoxic and ischaemic myocardium. Br. J. Pharmacol. 103(1):1991;1019-1026.
162. Nakazato M., Murakami N., Date Y., Kojima M., Matsuo H., Kangawa K., Matsukura S. A role for ghrelin in the central regulation of feeding. Nature. 409(6817):2001;194-198.
163. + channels. Science. 272(5270):1996;1950-1953.
164. Nelson M.T., Quayle J.M. Physiological roles and properties of potassium channels in arterial smooth muscle. Am. J. Physiol. 268(4 Part 1):1995;C799-822.
165. Nestorowicz A., Inagaki N., Gonoi T., Schoor K.P., Wilson B.A., Glaser B., Landau H., Stanley C.A., Thornton P.S., Seino S., Permutt M.A. A nonsense mutation in the inward rectifier potassium channel gene, Kir6.2, is associated with familial hyperinsulinism. Diabetes. 46(11):1997;1743-1748.
166. Nichols C.G., Lederer W.J. Adenosine triphosphate-sensitive potassium channels in the cardiovascular system. Am. J. Physiol. 261(6 Part 2):1991;H1675-1686.
167. Nichols C.G., Ripoll C., Lederer W.J. ATP-sensitive potassium channel modulation of the guinea pig ventricular action potential and contraction. Circ. Res. 68(1):1991;280-287.
168. Nichols C.G., Shyng S.L., Nestorowicz A., Glaser B., Clement J.P.t., Gonzalez G., Aguilar-Bryan L., Permutt M.A., Bryan J. Adenosine diphosphate as an intracellular regulator of insulin secretion. Science. 272(5269):1996;1785-1787.
169. Nielsen-Kudsk J.E., Bang L., Bronsgaard A.M. Glibenclamide blocks the relaxant action of pinacidil and cromakalim in airway smooth muscle. Eur. J. Pharmacol. 180(2-3):1990;291-296.
170. + channels in cardiac muscle. Nature. 305(5930):1983;147-148.
171. + channel in rat cultured cortical neurons. Pflugers Arch. 422(3):1992;260-266.
172. + channel expressed in a mammalian cell line, HEK293T cells. Pflugers Arch. 435(5):1998;595-603.
173. Oomura Y., Ono T., Ooyama H., Wayner M.J. Glucose and osmosensitive neurones of the rat hypothalamus. Nature. 222(190):1969;282-284.
174. Partridge C.J., Beech D.J., Sivaprasadarao A. Identification and pharmacological correction of a membrane trafficking defect associated with a mutation in the sulfonylurea receptor causing familial hyperinsulinism. J. Biol. Chem. 276(38):2001;35947-35952.
175. Patil N., Cox D.R., Bhat D., Faham M., Myers R.M., Peterson A.S. A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation. Nat. Genet. 11(2):1995;126-129.
176. + channel from rat liver and beef heart mitochondria. J. Biol. Chem. 267(36):1992;26062-26069.
177. ATP channels more complex than originally thought? J. Mol. Cell. Cardiol. 33(8):2001;1541-1546.
178. Prinzmetal M.et al. Angina pectoris. 1. A variant form of angina pectoris. preliminary report Am. J. Med. 27:1959;375-378.
179. Pristipino C., Beltrame J.F., Finocchiaro M.L., Hattori R., Fujita M., Mongiardo R., Cianflone D., Sanna T., Sasayama S., Maseri A. Major racial differences in coronary constrictor response between Japanese and Caucasians with recent myocardial infarction. Circulation. 101(10):2000;1102-1108.
180. + channel dependent mechanism. Diabetologia. 39(1):1996;22-27.
181. + currents in rabbit arterial smooth muscle via protein kinase a. J. Physiol. 475(1):1994;9-13.
182. + currents in smooth muscle cells from rabbit mesenteric artery. Am. J. Physiol. 269(5 Part 1):1995;C1112-1118.
183. Quayle J.M., Nelson M.T., Standen N.B. ATP-sensitive and inwardly rectifying potassium channels in smooth muscle. Physiol. Rev. 77(4):1997;1165-1232.
184. Reimann F., Ryder T.J., Tucker S.J., Ashcroft F.M. The role of lysine 185 in the Kir6.2 subunit of the ATP-sensitive channel in channel inhibition by ATP. J. Physiol. 520(Part 3):1999;661-669.
185. ATP channel activity via cAMP-dependent protein kinase in insulin-secreting cell lines. J. Gen. Physiol. 94(4):1989;693-717.
186. Rissanen J., Markkanen A., Karkkainen P., Pihlajamaki J., Kekalainen P., Mykkanen L., Kuusisto J., Karhapaa P., Niskanen L., Laakso M. Sulfonylurea receptor 1 gene variants are associated with gestational diabetes and type 2 diabetes but not with altered secretion of insulin. Diabetes Care. 23(1):2000;70-73.
187. ATP channels in rat dopaminergic substantia nigra neurones. Pflugers Arch. 430(1):1995;44-54.
188. +-channels in pancreatic beta-cells are regulated by intracellular ATP. Pflugers Arch. 405(4):1985;305-309.
189. Sakura H., Ammala C., Smith P.A., Gribble F.M., Ashcroft F.M. Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle. FEBS Lett. 377(3):1995;338-344.
190. Sakura H., Wat N., Horton V., Millns H., Turner R.C., Ashcroft F.M. Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel. no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro Diabetologia. 39(10):1996;1233-1236.
191. ATP channel conferred by a novel splice variant of SUR1. J. Physiol. 521(Part 2):1999;337-350.
192. +-channels by GTP-binding proteins in a mammalian cell line. J. Physiol. 507(Part 2):1998;315-324.
193. + current in cardiac muscle. Proc. Natl. Acad. Sci. USA. 85(21):1988;8360-8364.
194. Schiffrin E.L., Intengan H.D., Thibault G., Touyz R.M. Clinical significance of endothelin in cardiovascular disease. Curr. Opin. Cardiol. 12(4):1997;354-367.
195. Schwartz M.W., Woods S.C., Porte D. Jr., Seeley R.J., Baskin D.G. Central nervous system control of food intake. Nature. 404(6778):2000;661-671.
196. ATP channel-independent regulation of insulin secretion. J. Biol. Chem. 275(13):2000;9270-9277.
197. ATP channel subunits Kir6.1 and Kir6.2. J. Biol. Chem. 275(23):2000;17561-17565.
198. Seino S. ATP-sensitive potassium channels. a model of heteromultimeric potassium channel/receptor assemblies Annu. Rev. Physiol. 61:1999;337-362.
199. ATP channels learned from Kir6.2 genetically engineered mice. Diabetes. 49(3):2000;311-318.
200. Sgard F., Faure C., Drieu la Rochelle C., Graham D., O'Connor S.E., Janiak P., Besnard F. Regulation of ATP-sensitive potassium channel mRNA expression in rat kidney following ischemic injury. Biochem. Biophys. Res. Commun. 269(2):2000;618-622.
201. ATP channels. J. Biol. Chem. 274(29):1999;20628-20632.
202. ATP channel complex. J. Gen. Physiol. 110(6):1997;655-664.
203. ATP channels. Science. 282(5391):1998;1138-1141.
204. ATP channels by the Kir6.2 subunit. J. Gen. Physiol. 110(2):1997;141-153.
205. ATP channel activity by diazoxide and MgADP. Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor. J. Gen. Physiol. 110(6):1997;643-654.
206. ATP channels. J. Gen. Physiol. 116(5):2000;599-608.
207. + channels. Neuron. 16(2):1996;321-331.
208. Spanswick D., Smith M.A., Groppi V.E., Logan S.D., Ashford M.L. Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels. Nature. 390(6659):1997;521-525.
209. + channels in hypothalamic neurons of lean, but not obese rats. Nat. Neurosci. 3(8):2000;757-758.
210. Spruce A.E., Standen N.B., Stanfield P.R. Voltage-dependent ATP-sensitive potassium channels of skeletal muscle membrane. Nature. 316(6030):1985;736-738.
211. + channels in arterial smooth muscle. Science. 245(4914):1989;177-180.
212. Stanford I.M., Lacey M.G. Electrophysiological investigation of adenosine triphosphate-sensitive potassium channels in the rat substantia nigra pars reticulata. Neuroscience. 74(2):1996;499-509.
213. Stanley C.A., Lieu Y.K., Hsu B.Y., Burlina A.B., Greenberg C.R., Hopwood N.J., Perlman K., Rich B.H., Zammarchi E., Poncz M. Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene. N. Engl. J. Med. 338(19):1998;1352-1357.
214. Stirling B., Cox N.J., Bell G.I., Hanis C.L., Spielman R.S., Concannon P. Linkage studies in NIDDM with markers near the sulphonylurea receptor gene. Diabetologia. 38(12):1995;1479-1481.
215. Sturgess N.C., Ashford M.L., Cook D.L., Hales C.N. The sulphonylurea receptor may be an ATP-sensitive potassium channel. Lancet. 2(8453):1985;474-475.
216. Sturgess N.C., Kozlowski R.Z., Carrington C.A., Hales C.N., Ashford M.L. Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell line. Br. J. Pharmacol. 95(1):1988;83-94.
217. + channel subunit Kir6.2 in mouse pancreas. Diabetes. 46(9):1997;1440-1444.
218. Suzuki M., Fujikura K., Kotake K., Inagaki N., Seino S., Takata K. Immuno-localization of sulphonylurea receptor 1 in rat pancreas. Diabetologia. 42(10):1999;1204-1211.
219. Suzuki M., Li R.A., Miki T., Uemura H., Sakamoto N., Ohmoto-Sekine Y., Tamagawa M., Ogura T., Seino S., Marban E., Nakaya H. Functional roles of cardiac and vascular ATP-sensitive potassium channels clarified by Kir6.2-knockout mice. Circ. Res. 88(6):2001;570-577.
220. ATP channels in cardioprotection against ischemia/reperfusion injury in mice. J. Clin. Invest. 109(4):2002;509-516.
221. + channel in mitochondria. pharmacology and function J. Bioenerg. Biomembr. 28(2):1996;147-152.
222. Taborsky G.J. Jr., Ahren B., Havel P.J. Autonomic mediation of glucagon secretion during hypoglycemia. implications for impaired alpha-cell responses in type 1 diabetes Diabetes. 47(7):1998;995-1005.
223. Tanabe K., Tucker S.J., Ashcroft F.M., Proks P., Kioka N., Amachi T., Ueda K. Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide. Biochem. Biophys. Res. Commun. 272(2):2000;316-319.
224. Tanizawa Y., Matsuda K., Matsuo M., Ohta Y., Ochi N., Adachi M., Koga M., Mizuno S., Kajita M., Tanaka Y., Tachibana K., Inoue H., Furukawa S., Amachi T., Ueda K., Oka Y. Genetic analysis of Japanese patients with persistent hyperinsulinemic hypoglycemia of infancy. nucleotide-binding fold-2 mutation impairs cooperative binding of adenine nucleotides to sulfonylurea receptor 1 Diabetes. 49(1):2000;114-120.
225. ATP channels. J. Biol. Chem. 277(19):2002;17139-17146.
226. Thomas P., Ye Y., Lightner E. Mutation of the pancreatic islet inward rectifier Kir6.2 also leads to familial persistent hyperinsulinemic hypoglycemia of infancy. Hum. Mol. Genet. 5(11):1996;1809-1812.
227. Thomas P.M., Cote G.J., Wohllk N., Haddad B., Mathew P.M., Rabl W., Aguilar-Bryan L., Gagel R.F., Bryan J. Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science. 268(5209):1995;426-429.
228. + channels of cardiac myocytes. Mol. Pharmacol. 36(6):1989;897-902.
229. Tosaki A., Szerdahelyi P., Engelman R.M., Das D.K. Potassium channel openers and blockers. do they possess proarrhythmic or antiarrhythmic activity in ischemic and reperfused rat hearts? J. Pharmacol. Exp. Ther. 267(3):1993;1355-1362.
230. ATP channel mediation of anoxia-induced outward current in rat dorsal vagal neurons in vitro. J. Physiol. 487(Part 1):1995;37-50.
231. + channel in mouse pancreatic beta-cells. Pflugers Arch. 407(5):1986;493-499.
232. + channels in the absence of the sulphonylurea receptor. Nature. 387(6629):1997;179-183.
233. ATP channel inhibition by ATP. EMBO J. 17(12):1998;3290-3296.
234. Tusnady G.E., Bakos E., Varadi A., Sarkadi B. Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters. FEBS Lett. 402(1):1997;1-3.
235. 2+-independent ATP binding of the sulfonylurea receptor SUR1. J. Biol. Chem. 272(37):1997;22983-22986.
236. Ueda K., Komine J., Matsuo M., Seino S., Amachi T. Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide. Proc. Natl. Acad. Sci. USA. 96(4):1999;1268-1272.
237. Ueda K., Matsuo M., Tanabe K., Morita K., Kioka N., Amachi T. Comparative aspects of the function and mechanism of SUR1 and MDR1 proteins. Biochim. Biophys. Acta. 1461(2):1999;305-313.
238. Uhde I., Toman A., Gross I., Schwanstecher C., Schwanstecher M. Identification of the potassium channel opener site on sulfonylurea receptors. J. Biol. Chem. 274(40):1999;28079-28082.
239. + channel blocker glibenclamide and diaphragm fatigue during normoxia and hypoxia. J Appl Physiol. 85(2):1998;601-608.
240. Verkarre V., Fournet J.C., de Lonlay P., Gross-Morand M.S., Devillers M., Rahier J., Brunelle F., Robert J.J., Nihoul-Fekete C., Saudubray J.M., Junien C. Paternal mutation of the sulfonylurea receptor (SUR1) gene and maternal loss of 11p15 imprinted genes lead to persistent hyperinsulinism in focal adenomatous hyperplasia. J. Clin. Invest. 102(7):1998;1286-1291.
241. + channels recorded from sarcolemmal blebs of split fibers. ATP inhibition is reduced by magnesium and ADP J. Membr. Biol. 122(2):1991;165-175.
242. + channels by G-protein betagamma-subunits. EMBO J. 19(18):2000;4915-4925.
243. Walker J.E., Saraste M., Runswick M.J., Gay N.J. Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1(8):1982;945-951.
244. Wang P.H., Moller D., Flier J.S., Nayak R.C., Smith R.J. Coordinate regulation of glucose transporter function, number, and gene expression by insulin and sulfonylureas in L6 rat skeletal muscle cells. J. Clin. Invest. 84(1):1989;62-67.
245. Weik R., Neumcke B. ATP-sensitive potassium channels in adult mouse skeletal muscle. characterization of the ATP-binding site J. Membr. Biol. 110(3):1989;217-226.
246. + channel activation by calcitonin gene-related peptide and protein kinase A in pig coronary arterial smooth muscle. J. Physiol. 507(Part 1):1998;117-129.
247. Weston A.H., Edwards G. Recent progress in potassium channel opener pharmacology. Biochem. Pharmacol. 43(1):1992;47-54.
248. Wilde A.A. ATP-sensitive potassium channels, transmural ischemia and the ECG implications for the non-insulin dependent diabetic patient? Cardiovasc. Res. 31(5):1996;688-690.
249. Wilde A.A., Janse M.J. Electrophysiological effects of ATP sensitive potassium channel modulation. implications for arrhythmogenesis Cardiovasc. Res. 28(1):1994;16-24.
250. Woods S.C., Lotter E.C., McKay L.D., Porte D. Jr. Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons. Nature. 282(5738):1979;503-505.
251. Woods S.C., Seeley R.J., Porte D. Jr., Schwartz M.W. Signals that regulate food intake and energy homeostasis. Science. 280(5368):1998;1378-1383.
252. Xie L.H., Takano M., Kakei M., Okamura M., Noma A. Wortmannin, an inhibitor of phosphatidylinositol kinases, blocks the MgATP-dependent recovery of Kir6.2/SUR2A channels. J. Physiol. 514(Part 3):1999;655-665.
253. + channel. J. Physiol. 499(Part 3):1997;715-720.
254. Yamada K., Ji J.J., Yuan H., Miki T., Sato S., Horimoto N., Shimizu T., Seino S., Inagaki N. Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science. 292(5521):2001;1543-1546.
255. ATP channels. an endogenous protective mechanism during repetitive ischemia Am. J. Physiol. 264(2 Part 2):1993;H495-504.
256. Yasue H., Kugiyama K. Coronary spasm. clinical features and pathogenesis Int. Med. 36(11):1997;760-765.
257. + channels in pancreatic, cardiac, and vascular smooth muscle cells. Am. J. Physiol. 274(1 Part 1):1998;C25-37.
258. Zawar C., Plant T.D., Schirra C., Konnerth A., Neumcke B. Cell-type specific expression of ATP-sensitive potassium channels in the rat hippocampus. J. Physiol. 514(Part 2):1999;327-341.
259. ATP channels. Neuron. 22(3):1999;537-548.
260. Zhang H., Bolton T.B. Activation by intracellular GDP, metabolic inhibition and pinacidil of a glibenclamide-sensitive K-channel in smooth muscle cells of rat mesenteric artery. Br. J. Pharmacol. 114(3):1995;662-672.
261. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature. 372(6505):1994;425-432.
262. + conductance Neuron. 31(2):2001;233-245.
263. Zingman L.V., Hodgson D.M., Bast P.H., Kane G.C., Perez-Terzic C., Gumina R.J., Pucar D., Bienengraeber M., Dzeja P.P., Miki T., Seino S., Alekseev A.E., Terzic A. Kir6.2 is required for adaptation to stress. Proc. Natl. Acad. Sci. USA. 99(20):2002;13278-13283.