Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 KATP channels

Journal of Clinical Investigation

Volumn 110, Issue 2, 2002, Pages 203-208

  Chutkow, William A ^a   Pu, Jielin ^b   Wheeler, Matthew T ^a   Wada, Tomoyuki ^b   Makielski, Jonathan C ^b   Burant, Charles F ^c   McNally, Elizabeth M ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL; RECEPTOR SUBUNIT; SULFONYLUREA RECEPTOR; SULFONYLUREA RECEPTOR REGULATORY SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE MONITORING; CHANNEL GATING; CONTROLLED STUDY; CORONARY ARTERY CONSTRICTION; GENE TARGETING; HYPERTENSION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRINZMETAL ANGINA PECTORIS; PRIORITY JOURNAL; VASOMOTOR REFLEX; VASOSPASM;

EID: 0036071021     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI0215672     Document Type: Article

References (32)

1. ATP-regulated K+ channels in cardiac muscle
2. Properties and functions of ATP-sensitive K-channels
3. Reconstitution of 1KATP: An inward rectifier sub-unit plus the sulfonylurea receptor
4. Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart
5. Cloning of the beta cell high-affinity sulfonylurea receptor: A regulator of insulin secretion
6. Cloning, tissue expression, and chromosomal localization of SUR2, the putative drug-binding subunit of cardiac, skeletal muscle, and vascular KATP channels
7. A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels
8. A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel
9. Association and stoichiometry of K(ATP) channel subunits
10. Altered functional properties of KATP channel conferred by a novel splice variant of SUR1
11. Alternative splicing of sur2 exon 17 regulates nucleotide sensitivity of the ATP-sensitive potassium channel
12. ATP-sensitive potassium channel is essential to maintain basal coronary vascular tone in vivo
13. Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone
14. Hypoxic dilation of coronary arteries is mediated by ATP-sensitive potassium channels
15. ATP-sensitive and inwardly rectifying potassium channels in smooth muscle
16. Disruption of Sur2-containing KATP channels enhances insulin-stimulated glucose uptake in skeletal muscle
17. Sarcoplasmic reticulum buffering of myoplasmic calcium in bovine coronary artery smooth muscle
18. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
19. Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel
20. Disruption of the sarcoglycan-sarcospan complex in vascular smooth muscle: A novel mechanism for cardiomyopathy and muscular dystrophy
21. Nifedipine suppresses neointimal thickening by its inhibitory effect on vascular smooth muscle cell growth via a MEK-ERK pathway coupling with Pyk2
22. Artificial induction of melatonin rhythms by programmed microinfusion
23. Prinzmetal's variant angina
24. Efficacy of slow-release nifedipine on myocardial ischemic episodes in variant angina pectoris
25. Arterial dilations in response to calcitonin gene-related peptide involve activation of K+ channels
26. KATP channels in vascular smooth muscle
27. Coronary vasoconstrictive effects of neuropeptide Y and their modulation by the ATP-sensitive potassium channel in anesthetized dogs
28. Glibenclamide, a putative ATP-sensitive K+ channel blocker, inhibits coronary autoregulation in anesthetized dogs
29. Endothelium-derived vasoactive factors. 1. Endothelium-dependent relaxation
30. Molecular basis of electrocardiographic ST-segment elevation
31. Ischemic preconditioning: From adenosine receptor of KATP channel
32. The sulfonylurea controversy: More questions from the heart