Regulation of K(ATP) channel activity by diazoxide and MgADP: Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor

Journal of General Physiology

Volumn 110, Issue 6, 1997, Pages 643-654

  Shyng, S L ^a   Ferrigni, T ^a   Nichols, C G ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine diphosphate; Adenosine triphosphate; Diazoxide; Kir6.2; Sulfonylurea receptor

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; DIAZOXIDE; DRUG RECEPTOR; NUCLEOTIDE; POTASSIUM CHANNEL; POTASSIUM ION; RECEPTOR PROTEIN; SULFONYLUREA; ABC TRANSPORTER; ANTIHYPERTENSIVE AGENT; INWARDLY RECTIFYING POTASSIUM CHANNEL; MAGNESIUM; SULFONYLUREA DERIVATIVE; SULFONYLUREA RECEPTOR;

ANIMAL CELL; ARTICLE; CELL METABOLISM; CHANNEL GATING; CONTROLLED STUDY; HYDROLYSIS; MONKEY; NONHUMAN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS; ANIMAL; CELL STRAIN COS1; CHEMISTRY; DRUG EFFECT; GENETICS; KINETICS; METABOLISM; PATCH CLAMP; PHYSIOLOGY;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIHYPERTENSIVE AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; COS CELLS; DIAZOXIDE; HYDROLYSIS; ION CHANNEL GATING; KINETICS; MAGNESIUM; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN FOLDING; RECEPTORS, DRUG; SULFONYLUREA COMPOUNDS;

EID: 0030609142     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.110.6.643     Document Type: Article

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