ATP-sensitive potassium channels: A model of heteromultimeric potassium channel/receptor assemblies

Annual Review of Physiology

Volumn 61, Issue , 1999, Pages 337-362

  Seino, Susumu ^a  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

ADP; ATP binding cassette protein superfamily; Glibenclamide; Inward rectifiers; Sulfonylurea receptors

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; GUANINE NUCLEOTIDE BINDING PROTEIN; POTASSIUM CHANNEL; PROTEIN SUBUNIT; RECEPTOR SUBTYPE; SULFONYLUREA RECEPTOR;

GENE MUTATION; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE; REGULATORY MECHANISM; REVIEW; SITE DIRECTED MUTAGENESIS; STOICHIOMETRY; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; ELECTRIC CONDUCTIVITY; HUMANS; MUTATION; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, DRUG;

EID: 0033037098     PISSN: 00664278     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.physiol.61.1.337     Document Type: Review

References (137)

1. 1. Aguilar-Bryan L, Bryan J. 1997. ATP-sensitive potassium channels, sulfonylurea receptors, and persistent hyperinsulinemic hypoglycemia of infancy. Diabetes Rev. 4:336-46
2. ATP channels. Physiol. Rev. 78:227-45
3. 3. Aguilar-Bryan L, Nelson DA, Vu QA, Humphrey MB, Boyd AE III. 1990. Photoaffinity labeling and partial purification of the β cell sulfonylurea receptor using a novel, biologically active glyburide analog. J. Biol. Chem. 265:8218-24
4. 4. Aguilar-Bryan L, Nichols CG, Wechsler SW, Clement JP IV, Boyd AE III, et al. 1995. Cloning of the β cell high-affinity sulfonylurea receptor: a regulator of insulin secretion. Science 268:423-26
5. ATP channel gene expression in rat hearts. J. Clin. Invest. 100:3053-59
6. + channel. J. Membr. Biol. 159: 161-68
7. 2+ and pH. J. Physiol. 485:282-96
8. + channel Kir6.1 expressed in human embryonic kidney cells. J. Physiol. 494:709-14
9. 9. Ämmälä C, Moorhouse A, Gribble F, Ashfield R, Procks P, et al. 1996. Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels. Nature 379:545-48
10. 10. Ashcroft FM. 1988. Adenosine 5′-triphosphate-sensitive potassium channels. Annu. Rev. Neurosci. 11:97-118
11. 11. Ashcroft FM, Gribble FM. 1998. Correlating structure and function in ATP-sensitive potassium channels. Trends Neurosci. 21:288-94
12. 12. Ashcroft FM, Harrison DE, Ashcroft SJH. 1984. Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells. Nature 312:446-48
13. 13. Ashcroft SJH, Ashcroft FM. 1992. The sulfonylurea receptor. Biochim. Biophys. Acta 1175:45-59
14. 14. Ashford MLJ, Sturgess NC, Trout NJ, Gardner NJ, Hales CN. 1988. Adenosine-5′-triphosphate-sensitive ion channels in neonatal rat cultured central neurones. Pflügers Arch. 412:297-304
15. ATP channels. Annu. Rev. Physiol. 60:667-87
16. 15. Barry DM, Nerbonne JM. 1996. Myocardial potassium channels: electrophysiological and molecular diversity. Annu. Rev. Physiol. 58:363-94
17. 16. Beech DJ, Zhang H, Nakao K, Bolton TB. 1993. K channel activation by nucleotide diphosphates and its inhibition by glibenclamide in vascular smooth muscle cells. Br. J. Pharmacol. 110:573-82
18. 17. Bell GI, Kayano T, Buse JB, Burant CF, Takeda J, et al. 1990. Molecular biology of mammalian glucose transporters. Diabetes Care 13:198-208
19. + channels sensitive to antidiabetic sulfonylureas are present in adenohypophysis and are involved in growth hormone release. Proc. Natl. Acad. Sci. USA 90:1340-44
20. + channel. Proc. Natl. Acad. Sci. USA 85:9816-20
21. 20. Boyd AE III. 1988. Sulfonylurea receptors, ion channels, and fruit flies. Diabetes 37:847-50
22. 21. Bradbury NA, Jilling T, Berta G, Sorscher EJ, Bridges RJ, et al. 1992. Regulation of plasma membrane recycling by CFTR. Science 256:530-32
23. 22. Christie MJ, North RA, Osborne PB, Douglass J, Adelman JP. 1990. Heteropolymeric potassium channels expressed in Xenopus oocytes from cloned subunits. Neuron 2:405-11
24. ATP channels. Diabetes 45:1439-45
25. ATP channel subunits. Neuron 18:827-38
26. + channel that is sensitive to ATP. J. Neurosci. 16:1-9
27. + channels in pancreatic β-cells. Nature 311:271-73
28. + channels in pancreatic β-cells. Diabetes 37:495-98
29. 28. Dascal N, Lim NF, Schriebmayer W, Wang W, Davidson N, Lester HA. 1993. Expression of an atrial G-protein-activated potassium channel in Xenopus oocytes. Proc. Natl. Acad. Sci. USA 90: 6596-600
30. 29. Doupnik CA, Davidson N, Lester HA. 1995. The inward rectifier potassium channel family. Curr. Opin. Neurobiol. 5:268-77
31. ATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit. Proc. Natl. Acad. Sci. USA. 95:13953-58
32. 30. Dunne MJ, Kane C, Shepherd RM, Sanchez JA, James RFL, et al. 1997. Familial persistent hyperinsulinemic hypoglycemia of infancy and mutations in the sulfonylurea receptor. N. Engl. J. Med. 336:703-6
33. + channels in cultured pancreatic islet cells. J. Membr. Biol. 88:165-72
34. 32. Gaines KL, Hamilton S, Boyd AE III. 1988. Characterization of the sulfonylurea receptor on beta cell membranes. J. Biol. Chem. 263:2589-92
35. 33. Garlid KD. 1996. Cation transport in mitochondria - the potassium cycle. Biochem. Biophys. Acta 1275:123-26
36. 34. Glaser B, Chiu KC, Anker R, Nestorowiz A, Landau H, et al. 1994. Familial hyperinsulinism maps to chromosome 11p14-15. 1, 30 cM centromeric to the insulin gene. Nat. Genet. 7:185-88
37. + currents expressed in Xenopus oocytes. J. Physiol. 498:87-98
38. 36. Gribble FM, Tucker SJ, Asbcroft FM. 1997. The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide. J. 16:1145-52
39. 36a. Gribble FM, Tucker SJ, Seino S, Ashcroft FM. 1998. Tissue specificity of sulfonylureas. Studies on cloned cardiac and β-cell KATP channels. Diabetes 47: 1412-18
40. 37. Hansen L, Echwald SM, Hansen T, Urhammer SA, Clausen JO, et al. 1997. Amino acid polymorphisms in the ATP-regulatable inward rectifier Kir6.2 and their relationships to glucose-and tolbutamide-induced insulin secretion, the insulin sensitivity index, and NIDDM. Diabetes 46:508-12
41. 38. Hansen T, Echwald SM, Hansen L, Moller AM, Almind K, et al. 1998. Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene. Diabetes 47:598-605
42. 39. Hardy SP, Goodfellow HR, Valverde AM, Gill DR, Sepulveda FV, et al. 1995. Protein kinase C-mediated phosphorylation of the human multidrug resistance P-glycoprotein regulates cell volume-activated chloride channels. EMBO J. 14: 68-75
43. + channels. Science 258:1152-55
44. 41. Henquin JC. 1980. Tolbutamide stimulation and inhibition of insulin release: studies of the underlying ionic mechanisms in isolated rat islets. Diabetologia 18:151-60
45. 42. Hernandez-Sanchez C, Wood TL, Leroith D. 1997. Developmental and tissue-specific sulfonylurea receptor gene expression. Endocrinology 138:705-11
46. ATP channel: molecular cloning, expression, and biological properties. Proc. Natl. Acad. Sci. USA 95:8387-91
47. 43. Higgins CF. 1992. ABC transporters: from microorganisms to man. Annu. Rev. Cell Biol. 8:67-113
48. 44. Higgins CF. 1995. The ABC of channel regulation. Cell 82:693-96
49. 45. Ho K, Nichols CG, Lederer WJ, Lytton J, Vasselev PM, et al. 1993. Cloning and expression of an inwardly rectifying ATP-regulated potassium channel. Nature 362:31-38
50. 46. Hoshi T, Zagotta WN, Aldrich RW. 1990. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science 250:533-38
51. 47. Hunter M, Giebisch G. 1988. Calcium-activated K-channels of Amphiuma early distal tubule: inhibition by ATP. Pflügers Arch. 412:331-33
52. 48. Inagaki N, Gonoi T, Clement JP IV, Namba N, Inazawa J, et al. 1995. Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor. Science 270:1166-70
53. + channels. Neuron 16:1011-17
54. + channel. FEBS Lett. 409:232-36
55. ATP-1, gene (KCNJ8). Genomics 30:102-4
56. 52. Inagaki N, Tsuura Y, Namba N, Masuda K, Gonoi T, et al. 1995. Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart. J. Biol. Chem. 270:5691-94
57. + channel Kir6.2 (Bir) gene: identification and lack of role in Caucasian patients with NIDDM. Diabetes 46:502-7
58. + channel in the mitochondrial inner membrane. Nature 352:244-47
59. 55. Isocoff EY, Jan YN, Jan LY. 1990. Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes. Nature 345:530-34
60. + channel. J. Biol. Chem. 271:24321-24
61. + channel and linkage studies with NIDDM in Japanese. Diabetes 45: 267-69
62. 58. Jan LY, Jan Y. 1994. Potassium channels and their evolving gates. Nature 371:119-22
63. 59. Jan LY, Jan Y. 1997. Cloned potassium channels from eukaryotes and prokaryotes. Annu. Rev. Neurosci. 20:91-123
64. ATP channels in pancreatic β-cells causes persistent hyperinsulinemic hypoglycemia of infancy. Nat. Med. 2:1344-47
65. ATP channel-forming Kir6.2 subunit and the sulfonylurea receptor SUR1 in rodent brain. FEBS Lett. 401:59-64
66. 62. Kerr ID, Sansom MSP. 1995. Cation selectivity in ion channels. Nature 373:112
67. + channels are activated by Gβγ subunits and function as heteromultimers. Proc. Natl. Acad. Sci. USA 92:6542-46
68. +-channels. Diabetes Res. Clin. Pract. 28:67-80
69. 3H]glibenclamide. FEBS Lett. 229:355-59
70. + channel proteins. Nature 374:135-41
71. + channel with unique pore properties. Neuron 20:995-1005
72. 68. Kubo Y, Baldwin T, Jan YN, Jan LY. 1993. Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature 362:127-133
73. 69. Kubo Y, Reuveny E, Slesinger PA, Jan YN, Jan LY. 1993. Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel. Nature 364:802-6
74. 70. Kurachi Y. 1995. G protein regulation of cardiac muscarinic potassium channel. Am. J. Physiol. 269:C821-30
75. 71. Leonhardt N, Martin E, Vavasseur A, Forestier C. 1997. Evidence for the existence of a sulfonylurea-receptor-like protein in plants: modulation of stomatal movements and guard cell potassium channels by sulfonylureas and potassium channel openers. Proc. Natl. Acad. Sci. USA 94:14156-61
76. ATP channel requires two distinct segments of the cytoplasmic C-terminal domain of the pore-forming subunit. Biophys. J. 74:A241
77. + channel determined by construction of multimeric cDNAs. Neuron 9:861-71
78. + channel. Mol. Cell. Biol. 18:1652-59
79. 75. Lu C, Halvorsen SW. 1997. Channel activators regulate ATP-sensitive potassium channel (Kir6.1) expression in chick cardiomyocytes. FEBS Lett. 412:121-25
80. - currents in NIH/3T3 cells. Am. J. Physiol. 267:C650-58
81. ATP channel subunits to the plasma membrane. J. Biol. Chem. 273:3369-75
82. + channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator. Proc. Natl. Acad. Sci. USA 93:8083-88
83. + channel (ROMK2). Am. J. Physiol. 271:F275-85
84. ATP channel-deficient mice. Proc. Natl. Acad. Sci. USA 95:10402-6
85. ATP channel. Proc. Natl. Acad. Sci. USA 94:11969-73
86. 82. Misler S, Giebisch G. 1992. ATP-sensitive potassium channels in physiology, pathophysiology, and pharmacology. Curr. Opin. Nephrol. Hypertens. 1:21-33
87. 125I-labeled glyburide analog. J. Biol. Chem. 267:14928-33
88. 84. Nestorowicz A, Inagaki N, Gonoi T, Schoor KP, Wilson BA, et al. 1997. A nonsense mutation in the inward rectifier potassium channel gene, Kir6.2, is associated with familial hyperinsulinism. Diabetes 46:1743-48
89. 85. Nestorowicz A, Wilson BA, Schoor KP, Inoue H, Glaser B, et al. 1996. Mutations in the sulfonylurea receptor gene are associated with familial hyperinsulinism in Ashkenazi Jews. Hum. Mol. Genet. 5:1813-22
90. 86. Nichols CG, Lopatin AN. 1997. Inward rectifier potassium channels. Annu. Rev. Physiol. 59:171-91
91. 87. Nichols CG, Shyng S-L, Nestorowicz A, Glaser B, Clement CG IV, et al. 1996. Adenosine diphosphate as an intracellular regulator of insulin secretion. Science 272:1785-87
92. + channels in cardiac muscle. Nature 305:147-48
93. 89. North RA. 1995. Handbook of Receptors and Channels Series. Ligand-and Voltage-Gated Ion Channels. Boca Raton, FL: CRC Press
94. + channel expressed in a mammalian cell line, HEK239T cells. Pflügers Arch. 435:595-603
95. 91. Ozanne SE, Guest PC, Hutton JC, Hales CN. 1995. Intracellular localization and molecular heterogeneity of the sulphonylurea receptor in insulin-secreting cells. Diabetologia 38:277-82
96. 92. Permutt MA, Nestorowicz A, Glaser B. 1997. Familial hyperinsulinism: an inherited disorder of spontaneous hypoglycemia in neonates and infants. Diabetes Rev. 4:347-55
97. ATP channels is mediated by Kir6.2. Proc. Natl. Acad. Sci. USA 94:11716-2091
98. 94. Quayle JM, Nelson MT, Standen NB. 1997. ATP-sensitive and inwardly rectifying potassium channels in smooth muscle. Physiol. Rev. 77:1166-1215
99. 95. Ribalet B, Ciani S. 1987. Regulation by cell metabolism and adenine nucleotides of a K channel in insulin-secreting β cell (RINm5F). Proc. Natl. Acad. Sci. USA 84:1721-25
100. +-channels in pancreatic β-cells are regulated by intracellular ATP. Pflügers Arch. 405:305-9
101. 97. Ruppersberg JP, Schorter KH, Sakmann B, Stocker M, Sewing S, et al. 1990. Heteromultimeric channels formed by rat brain potassium-channel proteins. Nature 345:535-37
102. 98. Sakura H, Ämmälä C, Smith PA, Gribble FM, Ashcroft FM. 1995. Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic β-cells, brain, heart and skeletal muscle. FEBS Lett. 377:338-44
103. + channel: no association with NIDDM in white Caucasian subjects or evidence of abnormal function when expressed in vitro. Diabetologia 39:1233-36
104. + channels by GTP-binding proteins. J. Physiol. 507:315-24
105. + channel in insulin-secreting cells. J. Biol. Chem. 262:15840-44
106. 102. Schwanstecher M, Loser S, Chudziak F, Panten U. 1994. Identification of a 38-kDa high affinity sulfonylurea-binding peptide in insulin-secreting cells and cerebral cortex. J. Biol. Chem. 269:17768-71
107. + channel. Diabetes Rev. 4:177-90
108. ATP channels by the Kir6.2 subunit. J. Gen. Physiol. 110:141-53
109. ATP channel activity by diazoxide and MgADP distinct functions of the two nucleotide binding folds of the sulfonylurea receptor. J. Gen. Physiol. 110:643-54
110. ATP channel complex. J. Gen. Physiol. 110:655-64
111. 107. Spruce AE, Standen NB, Stanfield PR. 1985. Voltage-dependent ATP-sensitive potassium channels of skeletal muscle membrane. Nature 316:736-38
112. + channels in arterial smooth muscle. Science 245:177-80
113. 109. Sturgess NC, Ashford NLJ, Cook DL, Hales CN. 1985. The sulphonylurea receptor may be an ATP-sensitive potassium channel. Lancet 8453:474-75
114. 110. Stutts MJ, Canessa CM, Olsen JC, Hamrick M, Cohn JA, et al. 1995. CFTR as a cAMP-dependenl regulator of sodium channels. Science 269:847-50
115. + channel subunit Kir6.2 in mouse pancreas. Diabetes 46:1440-44
116. + channels in mitochondria. Biochem. Biophys. Res. Commun. 241:693-97
117. 113. Szewezyk A, Wojcik G, Lobanov NA, Nalecz MJ. 1997. The mitochondrial sulfonylurea receptor: identification and characterization. Biochem. Biophys. Res. Commun. 230:611-15
118. + channel-opening drugs. Am. J. Physiol. 269:C525-45
119. 115. Thomas PM, Cote GJ, Wohllk N, Haddad B, Mathew PM, et al. 1995. Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science 268:426-29
120. 116. Thomas PM, Wohllk N, Huang E, Kuhnle U, Rabl W, et al. 1996. Inactivation of the first nucleotide-binding fold of the sulfonylurea receptor, and familial persistent hyperinsulinemic hypoglycemia of infancy. Am. J. Hum. Genet. 59:510-18
121. 117. Trapp S, Tucker SJ, Ashcroft FM. 1997. Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits. Proc. Natl. Acad. Sci. USA 94:8872-77
122. 118. Trube G, Hescheler J. 1984. Inward-rectifying channels in isolated patches of the heart cell membrane: ATP-dependence and comparison with cell-attached patches. Pflügers Arch. 401:178-84
123. + channel in mouse pancreatic β-cells. Pflügers Arch. 407:493-99
124. + channel. Curr. Opin. Neurobiol. 8:316-320
125. ATP channel inhibition by ATP. EMBO J. 17:3290-96
126. + channels in the absence of the sulphonylurea receptor. Nature 387:179-83
127. 123. Tusnády GE, Bakos E, Varadi A, Sarkadi B. 1997. Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters. FEBS Lett. 402:1-3
128. 2+-independent ATP binding of the sulfonylurea receptor SUR1. J. Biol. Chem. 272:22983-86
129. 125. Virsolvy-Vergine A, Leray H, Kuroki S, Lupo B, Dufour M, et al. 1992. Endosulfine, an endogenous peptidic ligand for the sulfonylurea receptor: purification and partial characterization from ovine brain. Proc. Natl. Acad. Sci. USA 89: 6629-33
130. + channels recorded from sarcolemmal blebs of split fibers: ATP inhibition is reduced by magnesium and ADP. J. Membr. Biol. 122:165-75
131. 127. Walker JE, Saraste M, Runswick MJ, Gay N. 1982. Distantly related sequences in the α-and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1:945-51
132. 128. Weik R, Neumcke B. 1990. Effects of potassium channel openers on single potassium channels in mouse skeletal muscle. Naunyn-Schmied Arch. Pharmacol. 342:258-63
133. 129. Wickman K, Clapham DE. 1995. Ion channel regulation by G proteins. Physiol Rev. 75:865-85
134. 130. Woll KH, Lönnendonker U, Neumcke B. 1989. ATP-sensitive potassium channels in adult mouse skeletal muscle: different modes of blockage by internal cations, ATP and tolbutamide. Pflügers Arch. 414:622-28
135. + channel. J. Physiol. 499:715-20
136. 132. Yang J, Jan YN, Jan LY. 1995. Determination of the subunit stoichiometry of an inwardly rectifying potassium channel. Neuron 15:1441-47
137. 133. Zhang H-L, Bolton TB. 1996. Two types of ATP-sensitive potassium channels in rat portal vein smooth muscle cells. Br. J. Pharmacol. 118:105-14