Ischemic preconditioning: From adenosine receptor to K(ATP) channel

Annual Review of Physiology

Volumn 62, Issue , 2000, Pages 79-109

  Cohen, M V ^a   Baines, C P ^a   Downey, J M ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

MAPKAPK 2; P38 mitogen activated protein kinase; Protein kinase C; Tyrosine kinase

Indexed keywords

ADENOSINE 5' O (3 THIOTRIPHOSPHATE); ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATE; BRADYKININ; GUANINE NUCLEOTIDE BINDING PROTEIN; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE; OPIATE DERIVATIVE; OXYGEN RADICAL; POTASSIUM CHANNEL; PROTEIN KINASE; PROTEIN KINASE C;

ACTIN POLYMERIZATION; CHANNEL GATING; CYTOSKELETON; ENZYME PHOSPHORYLATION; GENE ACTIVATION; HEART INFARCTION; HEART INFARCTION PREVENTION; HEART MUSCLE REPERFUSION; NONHUMAN; PRIORITY JOURNAL; RABBIT; REVIEW; TISSUE NECROSIS;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; HUMANS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MYOCARDIUM; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RABBITS; RECEPTORS, PURINERGIC P1;

EID: 0033861720     PISSN: 00664278     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.physiol.62.1.79     Document Type: Review

References (147)

1. Signal transduction in ischemic preconditioning
2. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
3. Ischemic preconditioning protects against infarction in rat heart
4. 1 adenosine receptors in rabbit heart
5. No prevention of ischemic preconditioning by the protein kinase C inhibitor staurosporine in swine
6. + channel? Studies of contractile function after simulated ischemia in an atrial in vitro model
7. Preconditioning cultured human pediatric myocytes requires adenosine and protein kinase C
8. Preconditioning of ischemic myocardium: Reperfusion-induced arrhythmias
9. Preconditioning of the ischaemic myocardium; involvement of the L- arginine nitric oxide pathway
10. The local intracoronary administration of methylene blue prevents the pronounced antiarrhythmic effect of ischaemic preconditioning
11. Ischemic preconditioning attenuates acidosis and postischemic dysfunction in isolated rat heart
12. Reduction in infarct size after preconditioning does not predict the extent of early functional improvement of reperfused myocardium
13. The natural history of preconditioning: Cardioprotection depends on duration of transient ischemia and time to subsequent ischemia
14. Acadesine extends the window of protection afforded by ischaemic preconditioning in conscious rabbits
15. Infarct size limitation by preconditioning occurs in the absence of myocardial stunning
16. Nucleoside transport inhibitors enhance the infarct size-limiting effect of ischemic preconditioning
17. 2 receptor activation
18. Infarct limitation of the second window of protection in a conscious rabbit model
19. 1-selective adenosine analogues protects the heart against infarction
20. 3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart
21. 6-(3- iodobenzyl) adenosine-5'-N-methyluronamide protects against myocardial stunning and infarction without hemodynamic changes in conscious rabbits
22. 1 receptors, K(ATP) channels, and ischemic preconditioning in dogs
23. Involvement of endogenous adenosine in ischaemic preconditioning in swine
24. Cardioprotection provided by adenosine receptor activation is abolished by blockade of the K(ATP) channel
25. Preconditioning in isolated superfused human muscle
26. Ischemic preconditioning: Bioenergetic and metabolic changes and the role of endogenous adenosine
27. Protection of the heart by ischaemic preconditioning: Mechanisms and possibilities for pharmacological exploitation
28. Role of bradykinin in protection of ischemic preconditioning in rabbit hearts
29. Morphine mimics the cardioprotective effect of ischemic preconditioning via a glibenclamide-sensitive mechanism in the rat heart
30. Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits
31. Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardium
32. 1 receptor activation is abolished by protein kinase C inhibitors in the rabbit
33. 1-Adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase C
34. Pretreatment with endothelin-1 mimics ischemic preconditioning against infarction in isolated rabbit heart
35. Pretreatment with angiotensin II activates protein kinase C and limits myocardial infarction in isolated rabbit hearts
36. Effect of adenosine receptor blockade: Preventing protective preconditioning depends on time of initiation
37. Ischemic preconditioning induces selective translocation of protein kinase C isoforms ε and η in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity
38. Anchoring proteins for protein kinase C: A means for isozyme selectivity
39. Protein kinase C isozymes and substrates
40. Preconditioning protects ischemic rabbit heart by protein kinase C activation
41. Preconditioning of isolated rat heart is mediated by protein kinase C
42. Chelerythrine, a highly selective protein kinase C inhibitor, blocks the antiinfarct effect of ischemic preconditioning in rabbit hearts
43. Protein kinase C: Its role in ischemic preconditioning in the rat
44. Does ischemic preconditioning trigger translocation of protein kinase C in the canine model?
45. Role of activation of protein kinase C in the infarct size-limiting effect of ischemic preconditioning through activation of ecto-5'-nucleotidase
46. Prevention of ischemic preconditioning only by combined inhibition of protein kinase C and protein tyrosine kinase in pigs
47. A selective ε-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death
48. Implication of protein kinase C-α, δ, and ε isoforms in ischemic preconditioning in perfused rat hearts
49. Ischemic preconditioning translocates PKC-δ and -ε, which mediate functional protection in isolated rat heart
50. 2+ as a mediator of ischemic preconditioning
51. Hypoxia alters the subcellular distribution of protein kinase C isoforms in neonatal rat ventricular myocytes
52. Translocation of PKC, protein phosphatase inhibition and preconditioning of rabbit cardiomyocytes
53. Protection of ischemic preconditioning is dependent upon a critical timing sequence of protein kinase C activation
54. Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium
55. Delayed cardioprotection is associated with the sub-cellular relocalisation of ventricular protein kinase C ε, but not p42/44MAPK
56. A protein kinase C translocation inhibitor as an isozyme-selective antagonist of cardiac function
57. Peptide modulators of protein-protein interactions in intracellular signaling
58. The third helix of the Antennapedia homeodomain translocates through biological membranes
59. Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse
60. 3 receptor involvement
61. Preconditioning of isolated rabbit cardiomyocytes: Induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor
62. Potassium channels and preconditioning of isolated rabbit cardiomyocytes: Effects of glyburide and pinacidil
63. Protein kinase C-ε is responsible for the protection of preconditioning in rabbit cardiomyocytes
64. Oncogenes and signal transduction
65. Reduction in myocardial infarct size by basic fibroblast growth factor after temporary coronary occlusion in a canine model
66. aFGF induced cardioprotection in ischemic myocardium can be antagonized by Suramin
67. Insulin-like growth factor-II delays myocardial infarction in experimental coronary artery occlusion
68. Cardioprotective effect of insulin-like growth factor I in myocardial ischemia followed by reperfusion
69. Myocardial protection by insulin is dependent on phosphatidylinositol 3-kinase but not protein kinase C or K(ATP) channels in the isolated rabbit heart
70. The heterotrimeric G(q) protein-coupled angiotensin II receptor activates p21(ras) via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes
71. Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts
72. She adaptor proteins are key transducers of mitogenic signaling mediated by the G protein-coupled thrombin receptor
73. 2+- dependent signaling
74. Protein kinase C and protein tyrosine kinase activity contribute to mitogenic signaling by endothelin-1: Cross-talk between G protein-coupled receptors and pp60(c-src)
75. 2+ entry by tyrosine kinase inhibitors
76. Preconditioning triggers tyrosine kinase-phospholipase D signaling leading to activation of multiple protein kinases in heart
77. Phospholipase D plays a role in ischemic preconditioning in rabbit heart
78. Differential activation of mitogen-activated protein kinase and S6 kinase signaling pathways by 12-O-tetradecanoylphorbol-13-acetate (TPA) and insulin: Evidence for involvement of a TPA-stimulated protein-tyrosine kinase
79. Activation of protein kinase C stimulates the tyrosine phosphorylation and guanosine triphosphatase-activating protein association of p60 in rat hepatoma cells
80. Stimulation of tyrosine phosphorylation and mitogen-activated-protein (MAP) kinase activity in human SHSY5Y neuroblastoma cells by carbachol
81. Phosphotyrosine dependent targeting of mitogen-activated protein kinase in differentiated contractile vascular cells
82. Ischemic preconditioning triggers the activation of MAP kinases and MAPKAP kinase 2 in rat hearts
83. Protein tyrosine kinase is downstream of protein kinase C for ischemic preconditioning's anti-infarct effect in the rabbit heart
84. Tyrosine kinase is not involved in the infarct size-limiting effect of ischemic preconditioning in the canine heart
85. Ischemic preconditioning: Differences in protection and susceptibility to blockade with single-cycle versus multicycle transient ischemia
86. Effect of protein kinase C inhibitors on cardioprotection by ischemic preconditioning depends on the number of preconditioning episodes
87. Both protein kinase C (PKC) and tyrosine kinase contribute to cardioprotection by repetitive preconditioning in rats
88. Mitogen-activated protein kinase pathways
89. Intracellular signalling through protein kinases in the heart
90. p38 MAP kinase and not MEK 1 kinase is involved in ischemic preconditioning
91. Pro-inflammatory cytokines and environmental stress cause p38 mitogen- activated protein kinase activation by dual phosphorylation on tyrosine and threonine
92. 'Stress-responsive' mitogen-activated protein kinases (c-Jun N- terminal kinases and p38 mitogen-activated protein kinases) in the myocardium
93. Stimulation of 'stress-regulated' mitogen-activated protein kinases (stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen- activated protein kinases) in perfused rat hearts by oxidative and other stresses
94. 2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3: MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo
95. Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli
96. Activation of the p38 MAPK and the p46/p54 JNKs after brief episodes of ischemia/reperfusion in the heart of conscious rabbits
97. Involvement of protein kinase C and Src family tyrosine kinase in Gα(q/11-) induced activation of c-Jun N-terminal kinase and p38 mitogen- activated protein kinase
98. PKC ε isoform induces activation of the p42/p44 MAPKs and the p46/p54 JNKs in adult rabbit cardiac myocytes
99. Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
100. Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes
101. Interlekin-1 activates a novel protein kinase cascade that results in the phosphorylation of hsp27
102. Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27
103. HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress
104. Small heat shock proteins and protection against ischemic injury in cardiac myocytes
105. Ischaemia and the myocyte cytoskeleton: Review and speculation
106. Activation of MAPKAP kinase-2 by adenosine in rat heart
107. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by adenosine in the perfused rat heart
108. Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: A role in cardiac myocyte hypertrophy?
109. Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart
110. Ischemic preconditioning depends on interaction between mitochondrial K(ATP) channels and actin cytoskeleton
111. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
112. Phosphorylation state of hsp27 and p38 MAPK during preconditioning and protein phosphatase inhibitor protection of rabbit cardiomyocytes
113. Role of p38 MAP kinase in myocardial stress
114. An inhibitor of p38-mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia
115. The p38-MAPK inhibitor, SB203580, inhibits cardiac stress-activated protein kinases/ c-Jun N-terminal kinases (SAPKs/ JNKs)
116. Differential regulation of distinct protein kinase cascades by ischemia and ischemia/reperfusion in porcine myocardium
117. Stimulation of stress activated protein kinases by anisomycin protects ischemic myocardium
118. Activation of MAPKAPK2 is involved in preconditioned rabbit heart
119. +-channel
120. Toward understanding the assembly and structure of K(ATP) channels
121. Pharmacology of ATP-sensitive potassium channel (K(ATP)) openers in models of myocardial ischemia and reperfusion
122. Blockade of ATP-sensitive potassium channels increases infarct size but does not prevent preconditioning in rabbit hearts
123. Ketamine-xylazine anaesthesia permits a K(ATP) channel antagonist to attenuate preconditioning in rabbit myocardium
124. Limitation of myocardial infarct size in the rabbit by ischaemic preconditioning is abolished by sodium 5-hydroxydecanoate
125. Infarct limitation by protein kinase C (PKC) is attenuated by blockade of ATP-sensitive potassium (K(ATP)) channels
126. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs
127. Blockade of ischaemic preconditioning in dogs by the novel ATP dependent potassium channel antagonist sodium 5-hydroxydecanoate
128. Involvement of activation of ATP-dependent potassium channels in ischemic preconditioning in swine
129. The ischemia-selective K(ATP) channel antagonist, 5-hydroxydecanoate, blocks ischemic preconditioning in the rat heart
130. Effects of the K(ATP) channel opener bimakalim on coronary blood flow, monophasic action potential duration, and infarct size in dogs
131. Cardioprotection with the K(ATP) opener cromakalim is not correlated with ischemic myocardial action potential duration
132. Glyburide-reversible cardioprotective effect of BMS-180448 is independent of action potential shortening
133. Specific block of the antiischemic actions of cromakalim by sodium 5- hydroxydecanoate
134. + channels: Possible mechanism of cardioprotection
135. Mitochondrial ATP-dependent potassium channels: Novel effectors of cardioprotection?
136. Cloning and functional expression of a rat heart K(ATP) channel
137. + channels in insulinoma cells: Activation by somatostatin and protein kinase C and the role of cAMP
138. Polymyxin B has multiple blocking actions on the ATP-sensitive potassium channel in insulin-secreting cells
139. Regulation of adenosine triphosphate-sensitive potassium channels from rabbit ventricular myocytes by protein kinase C and type 2A protein phosphatase
140. + currents by protein kinase C and adenosine: Implications for ischemic preconditioning
141. 1 receptors by G proteins in rat ventricular myocytes
142. + channel is mediated by arachidonic acid metabolites
143. Direct activation of mammalian atrial muscarinic potassium channels by GTP regulatory protein G(k)
144. + channel
145. Cation transport in mitochondriathe potassium cycle
146. 2+ overload
147. Chloride channel inhibition blocks the protection of ischemic preconditioning and hypoosmotic stress in rabbit ventricular myocardium