Paternal mutation of the sulfonylurea receptor (SUR1) gene and maternal loss of 11p15 imprinted genes lead to persistent hyperinsulinism in focal adenomatous hyperplasia

Journal of Clinical Investigation

Volumn 102, Issue 7, 1998, Pages 1286-1291

  Verkarre, Virginie ^a,b   Fournet, Jean Christophe ^a,b   De Lonlay, Pascale ^a,b   Gross Morand, Marie Sylvie ^a   Devillers, Martine ^a   Rahier, Jacques ^c   Brunelle, Francis ^b   Robert, Jean Jacques ^b   Nihoul Fékété, Claire ^b   Saudubray, Jean Marie ^b   Junien, Claudine ^a,b  

^a INSERM   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

Author keywords

Beckwith Wiedemann syndrome; K+(ATP) channel; Loss of alleles; Neonatal hypoglycemia; Persistent hyperinsulinism

Indexed keywords

DNA; POTASSIUM ION; SULFONYLUREA;

ALLELE; ARTICLE; BECKWITH WIEDEMANN SYNDROME; CHROMOSOME 11P; CLINICAL ARTICLE; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; HYPERINSULINEMIA; HYPOGLYCEMIA; NEWBORN DISEASE; NUCLEOTIDE SEQUENCE; PANCREAS ISLET CELL HYPERPLASIA; PRIORITY JOURNAL;

EID: 0032190017     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI4495     Document Type: Article

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