CASK: A novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins

Journal of Neuroscience

Volumn 16, Issue 8, 1996, Pages 2488-2494

  Hata, Yutaka ^a,b   Butz, Stefan ^a   Südhof, Thomas C ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

CaM kinase; disks large; intercellular junctions; neurexins; synapse; yeast two hybrid

Indexed keywords

CELL SURFACE PROTEIN; COMPLEMENTARY DNA; PROTEIN KINASE (CALCIUM,CALMODULIN);

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SYNAPSE; YEAST;

EID: 0029914941     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-08-02488.1996     Document Type: Article

References (42)

1. Alloisio N, Venezia ND, Rana A, Andrabi K, Texier P, Gilsanz F, Cartro J-P, Delaunay J, Chisti AH (1993) Evidence that red blood cell protein p55 may participate in the skeleton-membrane linkage that involves protein 4.1 and glycophorin C. Blood 82:1323-1327.
2. 2+/calmodulin-dependent protein kinase determined by molecular cloning. Proc Natl Acad Sci USA 84:1794-1798.
3. 2-domain proteins. J Biol Chem 270:25273-25280.
4. Cho K-O, Hunt CA, Kennedy MB (1992) The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron 9:929-942.
5. Davletov BA, Krasnoperov V, Hata Y, Petrenko AG, Südhof TC (1995) High affinity binding of α-latrotoxin to recombinant neurexin Iα. J Biol Chem 270:23903-23905.
6. Fields S, Song O (1989) A novel genetic system to detect protein-protein interaction. Nature 340:245-246.
7. 2+ sensor for transmitter release at a central synapse. Cell 79:717-727.
8. Guan KL, Dixon JE (1991) Eukaryotic proteins expressed in Escherischia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal Biochem 192:262-267.
9. Hanley RM, Means AR, Kemp BE, Burgin KE, Waxham N, Kelly PT (1987) Functional analysis of a complementary DNA for the 50-kilodalton subunit of calmodulin kinase II. Science 237:293-297.
10. 2+/calmodulin-dependent protein kinases. Annu Rev Biochem 61:559-601.
11. Haribabu B, Hook SS, Selbert MA, Goldstein EG Tomhave ED, Edelman AM, Snyderman R, Means AR (1995) Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase. EMBO J 14:3679-3686.
12. Hata Y, Südhof TC (1995) A novel ubiquitous form of munc18 interacts with multiple syntaxins. J Biol Chem 270:13022-13028.
13. Hata Y, Davletov B, Petrenko AG, Jahn R, Südhof TC (1993) Interaction of synaptotagmin with the cytoplasmic domains of neurexins. Neuron 10:307-315.
14. Ichtchenko K, Hata Y, Nguyen T, Ullrich B, Missler M, Moomaw C, Südhof TC (1995) Neuroligin 1: a splice-site specific ligand for β-neurexins. Cell 81:435-443.
15. Ichtchenko K, Nguyen T, Südhof TC (1996) Structures, alternative splicing, and neurexin binding of multiple neurligins J Biol Chem 271:2676-2682.
16. Itoh MS, Nagafuchi S, Yonemura R, Kitani-Yasuda T, Tsukita S, Tsukita S (1993) The 220 kDa protein colocalizaing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J Cell Biol 121:491-502.
17. Jesaitis LA, Goodenough DA (1994) Molecular characterizaiton and tissue distribution of ZO-2, a tight junction protein homologuos to ZO-1 and the Drosophila discs-large tumor supressor protein. J Cell Biol 124:949-961.
18. Johnston PA, Jahn R, Südhof TC (1989) Transmembrane topography and evolutionary conservation of synaptophysin. J Biol Chem 264:1268-1273.
19. Jones DH, Matus I (1974) Isolation of synaptic plasma membrane from brain by combined flotation-sedimentation density gradient centrifugation. Biochim Biophys Acta 356:276-287.
20. Kistner U, Wenzel BM, Veh RW, Cases-Langhoff C, Garner C (1993) SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A. J Biol Chem 268:4580-4583.
21. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
22. Lin CR, Kaplioff MS, Durgerian S, Takemoto K, Russo AF, Hanson P, Schulman H, Rosenfeld MG (1987) Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase. Proc Natl Acad Sci USA 84:5962-5966.
23. Lue RA, Marfatia SM, Branton D, Chishti AH (1994) Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1. Proc Natl Acad Sci USA 91:9818-9822.
24. Marfatia SM, Lue RA, Branton D, Chishti AH (1994) In vitro binding studies suggest a membrane-associated complex between erythroid p55, protein 4.1, and glycophorin C. J Biol Chem 269:8631-8634.
25. Mazoyer S, Gayther SA, Nagai MA, Smith SA, Dunning A, van Rensburg EJ, Albertsen H, White R, Ponder BAJ (1995) A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dlg-A. Genomics 28:25-31.
26. Müller BM, Kistner U, Veh RW, Cases-Langhoff C, Becker B, Gundelfinger ED, Garner CC (1995) Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor supressor protein. J Neurosci 15:2354-2366.
27. Petrenko AG, Perin MS, Davletov BA, Ushkaryov YA, Geppert M, Südhof TC (1991) Binding of synaptotagmin to the α-latrotoxin receptor implicates both in synaptic vesicle exocytosis. Nature 353:65-68.
28. Rose MD, Winston F, Hieter P (1990) Methods in yeast genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
29. Ruff P, Speicher DW, Husain-Chishti A (1991) Molecular identification of a major palmitoylated erythocyte membrane protein containing a src homology 3 motif. Proc Natl Acad Sci USA 88:6595-6599.
30. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning, a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
31. Schiestl RH, Gietz RD (1989) High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr Genet 16:339-346.
32. Sontag JM, Fykse EM, Ushkaryov YA, Liu JP, Robinson PJ, Südhof TC (1994) Differential expression and regulation of multiple dynamins. J Biol Chem 269:4547-4554.
33. 2+/calmodulin-dependent protein kinase cascade. J Biol Chem 270:19320-19324.
34. Tsukita S, Itoh M, Nagafuchi A, Yonemura S, Tsukita S (1993) Submembranous junctional plaques proteins include potential tumor suppressor molecules. J Cell Biol 123:1049-1053.
35. Ullrich B, Ushkaryov YA, Südhof TC (1995) Cartography of neurexins: more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons. Neuron 14:497-507.
36. Ushkaryov YA, Südhof TC (1993) Neurexin IIIα: extensive alternative splicing generates membrane-bound and soluble forms in a novel neurexin. Proc Natl Acad Sci USA 90:6410-6414.
37. Ushkaryov YA, Petrenko AG, Geppert M, Südhof TC (1992) Neurexins: synaptic cell surface proteins related to the α-latrotoxin receptor and laminin. Science 257:50-56.
38. Ushkaryov YA, Hata Y, Ichtchenko K, Moomaw C, Afendis S, Slaughter CA, Südhof TC (1994) Conserved domain structure of β-neurexins. J Biol Chem 269:11987-11992.
39. Vojtek AB, Hollenberg SM, Cooper JA (1993) Mammalian ras interacts directly with the serin/threonine kinase raf. Cell 74:205-214.
40. Ward AC (1990) Single-step purification of shuttle vectors from yeast for high frequency back-transformation into E. coli. Nucleic Acids Res 18:5319.
41. Willott E, Balda MS, Fanning AS, Jameson B, Van Itallie C, Anderson JM (1993) The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions. Proc Natl Acad Sci 90:7834-7838.
42. Woods DF, Bryant PJ (1991) The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions. Cell 66:451-464.