-
1
-
-
0025322132
-
Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease
-
(1990)
N. Engl. J. Med.
, vol.322
, pp. 1293-1298
-
-
Albin, R.L.1
Young, A.B.2
Penney, J.B.3
Handelin, B.4
Balfour, R.5
Anderson, K.D.6
Markel, D.S.7
Tourtellotte, W.W.8
Reiner, A.9
-
15
-
-
7144253143
-
Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 783-790
-
-
Cooper, J.K.1
Schilling, G.2
Peters, M.F.3
Herring, W.J.4
Sharp, A.H.5
Kaminsky, Z.6
Masone, J.7
Khan, F.A.8
Delanoy, M.9
Borchelt, D.R.10
Dawson, V.L.11
Dawson, T.M.12
Ross, C.A.13
-
17
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
DiFiglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
Wanker, E.E.8
Mangiarini, L.9
Bates, G.P.10
-
20
-
-
0028989602
-
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
-
(1995)
Neuron
, vol.14
, pp. 1075-1081
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.3
Schwarz, C.4
Meloni, A.5
Young, C.6
Martin, E.7
Vonsattel, J.P.8
Carraway, R.9
Reeves, S.A.10
Boyce, F.M.11
Aronin, N.12
-
25
-
-
0033557661
-
Cellular localization of hutingtin in striatal and cortical neurons in rats: Lack of correlation with neuronal vulnerability in Huntington's disease
-
(1999)
J. Neurosci.
, vol.19
, pp. 1189-1202
-
-
Fusco, F.R.1
Chen, Q.2
Lamoreaux, W.J.3
Figueredo-Cardenas, G.4
Jiao, Y.5
Coffman, J.A.6
Surmeier, D.J.7
Honig, M.G.8
Carlock, L.R.9
Reiner, A.10
-
27
-
-
9044229711
-
Absence of disease phenotype and intergenerational stability of the CAG repeat in transgenic mice expressing the human Huntington disease transcript
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 177-183
-
-
Goldberg, Y.P.1
Kalchman, M.A.2
Metzler, M.3
Nasir, J.4
Zeisler, J.5
Graham, R.6
Koide, H.B.7
O'Kusky, J.8
Sharp, A.H.9
Ross, C.A.10
Jirik, F.11
Hayden, M.R.12
-
28
-
-
0032903191
-
Calcium ionophores can induce either apoptosis or necrosis in cultured cortical neurons
-
(1999)
Neuroscience
, vol.90
, pp. 1339-1348
-
-
Gwag, B.J.1
Canzoniero, L.M.T.2
Sensi, S.L.3
Demaro, J.A.4
Koh, J.Y.5
Goldberg, M.P.6
Jacquin, M.7
Choi, D.W.8
-
29
-
-
0032101287
-
The influence of huntingtin protein size on nuclear localization and cellular toxicity
-
(1998)
J. Cell Biol.
, vol.141
, pp. 1097-1105
-
-
Hackam, A.S.1
Singaraja, R.2
Wellington, C.L.3
Metzler, M.4
McCutcheon, K.5
Zhang, T.6
Kalchman, M.7
Hayden, M.R.8
-
33
-
-
0033136692
-
A YAC transgenic mouse model for Huntington disease: Expression of full-length mutant huntingtin demonstrates initial cytoplasmic toxicity followed by a neurological phenotype and selective striatal neurodegeneration
-
(1999)
Neuron
, vol.23
, pp. 181-192
-
-
Hodgson, J.G.1
Agopyan, N.2
Gutekunst, C.-A.3
Smith, D.J.4
LePiane, F.5
Bissada, N.6
McCutcheon, K.7
Nasir, J.8
Singaraja, R.9
Jamot, L.10
Li, X.-J.11
Leavitt, B.R.12
Roder, J.C.13
Phillips, A.G.14
Rubin, E.M.15
Hersch, S.M.16
Hayden, M.R.17
-
35
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
36
-
-
0030986659
-
HIP1, an human homolog of S cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
-
(1997)
Nature Genet.
, vol.16
, pp. 44-53
-
-
Kalchman, M.A.1
Koide, H.B.2
McCutcheon, K.3
Graham, R.K.4
Nichol, K.5
Nishiyama, K.6
Kazemi-Esfarjani, P.7
Lynn, F.C.8
Wellington, C.L.9
Metzler, M.10
Goldberg, Y.P.11
Kanazawa, I.12
Gietz, R.D.13
Hayden, M.R.14
-
39
-
-
0023221068
-
Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay
-
(1987)
J. Neurosci. Methods
, vol.20
, pp. 83-90
-
-
Koh, J.Y.1
Choi, D.W.2
-
45
-
-
0033571743
-
Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease
-
(1999)
J. Neurosci. Res.
, vol.58
, pp. 515-532
-
-
Levine, M.S.1
Klapstein, G.J.2
Koppel, A.3
Gruen, E.4
Cepeda, C.5
Vargas, M.E.6
Jokel, E.S.7
Carpenter, E.M.8
Zanjani, H.9
Hurst, R.S.10
Efstratiadis, A.11
Zeitlin, S.12
Chesselet, M.-F.13
-
46
-
-
0027484673
-
Huntington's disease gene (IT15) is widely expressed in human rat tissues
-
(1993)
Neuron
, vol.11
, pp. 985-993
-
-
Li, S.-H.1
Schilling, G.2
Young III, W.S.3
Li, X.-J.4
Margolis, R.L.5
Stine, O.C.6
Wagster, M.V.7
Abbott, M.H.8
Franz, M.L.9
Ranin, N.G.10
Folstein, S.E.11
Hedreen, J.C.12
Ross, C.A.13
-
47
-
-
0028803757
-
A huntingtin-associated protein enriched in brain with implications for pathology
-
(1995)
Nature
, vol.378
, pp. 398-402
-
-
Li, X.-J.1
Li, S.-H.2
Sharp, A.H.3
Nucifora F.C., Jr.4
Schilling, G.5
Lanahan, A.6
Worley, P.7
Snyder, S.H.8
Ross, C.A.9
-
50
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lahrach, H.9
Davies, S.W.10
Bates, G.P.11
-
51
-
-
0032168178
-
Role of the carboxy-terminal region of the GluRε2 subunit in synaptic localization of the NMDA receptor channel
-
(1998)
Neuron
, vol.21
, pp. 571-580
-
-
Mori, H.1
Manabe, T.2
Watanabe, M.3
Satoh, Y.4
Suzuki, N.5
Toki, S.6
Nakamura, K.7
Yagi, T.8
Kushiya, E.9
Takahashi, T.10
Inoue, Y.11
Sakimura, K.12
Mishina, M.13
-
52
-
-
0039793622
-
SAP102, a novel postsynaptic protein that interacts with NMDA receptor complexes in vivo
-
(1996)
Neuron
, vol.17
, pp. 255-265
-
-
Muller, B.M.1
Kistner, U.2
Kindler, S.3
Chung, W.J.4
Kuhlendahl, S.5
Fenster, S.D.6
Lau, L.-F.7
Veh, R.W.8
Huganir, R.L.9
Gundelfinger, E.D.10
Garner, C.C.11
-
58
-
-
17344367977
-
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA
-
(1998)
Nature Genet.
, vol.20
, pp. 198-202
-
-
Reddy, P.H.1
Williams, M.2
Charles, V.3
Garrett, L.4
Pike-Buchanan, L.5
Whetsell W.O., Jr.6
Miller, G.7
Tagle, D.A.8
-
59
-
-
20244375528
-
The messenger RNAs for the N-methyl-D-aspartate receptor subunits show region-specific expression of different subunit composition in the human brain
-
(1996)
Neuroscience
, vol.73
, pp. 429-497
-
-
Rigby, M.1
Le Bourdelles, B.2
Heavens, R.P.3
Kelly, S.4
Smith, D.5
Butler, A.6
Hammans, R.7
Hills, R.8
Xuereb, J.H.9
Hill, R.G.10
Whiting, P.J.11
Sirinathsinghji, D.J.S.12
-
61
-
-
0029089172
-
When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases
-
(1995)
Neuron
, vol.15
, pp. 493-496
-
-
Ross, C.A.1
-
65
-
-
0030771894
-
Huntingtin localization in brain of normal and Huntington's-disease patients
-
(1997)
Annal. Neurol.
, vol.42
, pp. 604-612
-
-
Sapp, E.1
Schwarz, C.2
Chase, K.3
Bhide, P.G.4
Young, A.B.5
Penney, J.6
Vonsattel, J.P.7
Aronin, N.8
DiFiglia, M.9
-
67
-
-
0032559283
-
Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo
-
(1998)
Cell
, vol.92
, pp. 279-289
-
-
Sprengel, R.1
Suchanek, B.2
Amico, C.3
Brusa, R.4
Burnahev, N.5
Rozov, A.6
Hvalby, O.7
Jensen, V.8
Paulsen, O.9
Anderson, P.10
Kim, J.J.11
Thompson, R.F.12
Sun, W.13
Webster, L.C.14
Grant, S.G.N.15
Eilers, J.16
Konnerth, A.17
Li, J.18
McNamara, J.O.19
Seeburg, P.H.20
more..
-
68
-
-
0031056478
-
HIP-1: A huntingtin interacting protein isolated by the yeast two-hybrid system
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 487-495
-
-
Wanker, E.E.1
Rovira, C.2
Scherzinger, E.3
Hasenbank, R.4
Walter, S.5
Tait, D.6
Colicelli, J.7
Lehrach, H.8
|