Altered interaction between PSD-95 and the NMDA receptor following transient global ischemia

Journal of Neurochemistry

Volumn 74, Issue 1, 2000, Pages 169-178

  Takagi, Norio ^a,b   Logan, Richard ^a   Teves, Lucy ^a   Wallace, M Christopher ^a   Gurd, James W ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Ischemia; Kainate receptor; Neuronal nitric oxide synthase; NMDA receptor; Postsynaptic density; PSD 95

Indexed keywords

BINDING PROTEIN; KAINIC ACID RECEPTOR; MEMBRANE PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTRANSMITTER RECEPTOR; NITRIC OXIDE SYNTHASE; RECEPTOR SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; CYTOSKELETON; HIPPOCAMPUS; MALE; MOLECULAR INTERACTION; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; REPERFUSION; SOLUBILITY;

ANIMALS; DENTATE GYRUS; DEOXYCHOLIC ACID; DETERGENTS; GTPASE-ACTIVATING PROTEINS; HIPPOCAMPUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISCHEMIC ATTACK, TRANSIENT; MALE; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; NEUROPEPTIDES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; RATS; RATS, WISTAR; RECEPTORS, KAINIC ACID; RECEPTORS, N-METHYL-D-ASPARTATE; SOLUBILITY; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0033981952     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0740169.x     Document Type: Article

References (54)

1. Allison D. W., Gelfand I. V., Spector I., and Craig A. M. (1998) Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: differential attachment of NMDA versus AMPA receptors. J. Neurosci. 18, 2423-2436.
2. Blahos J. II and Wenthold R. J. (1996) Relationship between N-methyl-D-aspartate receptor NR1 splice variants and NR2 subunits. J. Biol. Chem. 271, 15669-15674.
3. Brenman J. E., Christopherson K. S., Craven S. E., McGee A. V., and Bredt D. S. (1996a) Cloning and characterization of postsynaptic density 93, a nitric oxide synthase interacting protein. J. Neurosci. 16, 7407-7415.
4. Brenman J. E., Chao D. S., Gee S. H., McGee A. W., Craven S. E., Santillano D. R., Wu Z., Huang F., Xia H., Peters M. F., Froehner S. C., and Bredt D. S. (1996b) Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and 1-syntrophin mediated by PDZ domains. Cell 84, 757-767.
5. Chen H.-J., Rojas-Soto M., Oguni A., and Kennedy M. B. (1998) A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II. Neuron 20, 895-904.
6. Cho K.-O., Hunt C. A., and Kennedy M. B. (1992) The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron 9, 929-942.
7. + channel Kir 2.3 to PSD-95 is regulated by protein kinase A phosphorylation. Neuron 17, 759-767.
8. Craven S. E. and Bredt D. S. (1998) PDZ proteins organize synaptic signaling pathways. Cell 93, 495-498.
9. Deguchi M., Hata Y., Takeuchi M., Ide N., Hirao K., Yao I., Irie M., Toyoda A., and Takai Y. (1998) BEGAIN (brain-enriched guanylate kinase-associated protein), a novel neuronal PSD-95/SAP90-binding protein. J. Biol. Chem. 273, 26269-26272.
10. Ehlers M. D., Zhang S., Bernhadt J. P., and Huganir R. L. (1996) Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit. Cell 84, 745-755.
11. Garcia E. P., Mehta S., Blair L. A. C., Wells D. G., Shang J., Fukushima T., Fallon J. R., Garner C. C., and Marshall J. (1998) SAP90 binds and clusters kainate receptors causing incomplete desensitization. Neuron 21, 727-739.
12. Gurd J. W., Bissoon N., and Soulliere J. (1992) Procedures for analyzing the tyrosine phosphorylation of synaptic proteins. Neuroprotocols 1, 207-214.
13. + exchange. Nature 392, 626-630.
14. Hirao K., Hata Y., Ide N., Takeuchi M., Irie M., Yao I., Deguchi M., Toyoda A., Sudhof T. C., and Takai Y. (1998) A novel multiple PDZ domain-containing molecule interacting with N-methyl-D-aspartate receptors and neuronal cell adhesion proteins. J. Biol. Chem. 273, 21105-21110.
15. Hock B., Böhme B., Karn T., Yamamoto T., Kaibuchi K., Holtrich U., Holland S., Pawson T., Rübsamen-Waigmann H., and Strebhardt K. (1998) PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor. Proc. Natl. Acad. Sci. USA 95, 9779-9784.
16. Hsueh Y.-P. and Sheng M. (1999) Requirement of N-terminal cysteines of PSD-95 for PSD-95 multimerization and ternary complex formation, but not for binding to potassium channel Kv1.4. J. Biol. Chem. 274, 532-536.
17. Hsueh Y.-P., Kim E., and Sheng M. (1997) Disulfide-linked head-to-head multimerization in the mechanism of ion channel clustering by PSD-95. Neuron 18, 803-814.
18. Hu B.-R., Park M., Martone M. E., Fischer W. H., Ellisman M. H., and Zivin J. A. (1998) Assembly of proteins to the postsynaptic density after transient cerebral ischemia. J. Neurosci. 18, 625-633.
19. Hunt C. A., Schenker L. J., and Kennedy M. B. (1996) PSD-95 is associated with the postsynaptic density and not with the presynaptic membrane at forebrain synapses. J. Neurosci. 16, 1380-1388.
20. Irie M., Hata Y., Takeuchi M., Ichtchenko K., Toyoda A., Hirao K., Takai Y., Rosahl T. W., and Sudhof T. C. (1997) Binding of neuroligans to PSD-95. Science 277, 1511-1515.
21. Jo K., Derin R., Li M., and Bredt D. S. (1999) Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex. J. Neurosci. 19, 4189-4199.
22. Kennedy M. B. (1997) The postsynaptic density at glutamatergic synapses. Trends Neurosci. 20, 264-268.
23. Kim E., Cho K.-O., Rothschild A., and Sheng M. (1996) Heteromultimerization and NMDA receptor-clustering activity of chapsyn-110, a member of the PSD-95 family of proteins. Neuron 17, 103-113.
24. Kim J. H. and Huganir R. L. (1999) Organization and regulation of proteins at the synapse. Curr. Opin. Cell Biol. 11, 248-254.
25. Kim J. H., Liao D., Lau L.-F., and Huganir R. L. (1998) SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family. Neuron 20, 683-691.
26. Kirino T. (1982) Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 239, 57-69.
27. Klauck T. M. and Scott J. D. (1995) The postsynaptic density: a subcellular anchor for signal transduction enzymes. Cell. Signal. 7, 747-757.
28. Kornau H.-C., Schenker L. T., Kennedy M. B., and Seeburg P. H. (1995) Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 269, 1737-1740.
29. Lau L.-F., Mammen A., Ehlers M. D., Kindler S., Chung W. J., Garner C. C., and Huganir R. L. (1996) Interaction of the N-methyl-D-aspartate receptor complex with a novel synapse-associated protein. SAP102. J. Biol. Chem. 271, 21622-21628.
30. Lin J. W., Wyszynski M., Madhavan R., Sealock R., Kim J. U., and Sheng M. (1998) Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1. J. Neurosci. 18, 2017-2027.
31. Lowry O. H., Rosebrough N. J., Farr A. L., and Randall R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
32. Martone M. E., Jones Y. Z., Young S. J., Ellisman M. H., Zivin J. A., and Hu B.-R. (1999) Modification of postsynaptic densities after transient cerebral ischemia: a quantitative and three-dimensional ultrastructural study. J. Neurosci. 19, 1988-1997.
33. Migaud M., Charlesworth P., Dempster M., Webster L. C., Watabe A. M., Makhinson M., He Y., Ramsay M. F., Morris R. G., Morrison J. H., O'Dell T. J., and Grant S. G. (1998) Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein. Nature 396, 433-439.
34. Müller B. M., Kistner U., Veh R. W., Cases-Langhoff C., Becker B., Gundelfinger E. D., and Garner C. C. (1995) Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein. J. Neurosci. 15, 2354-2366.
35. Müller B. M., Kistner U., Kindler S., Chung W. J., Kuhlendahl S., Fenster S. D., Lau L.-F., Veh R. W., Huganir R. L., Gundelfinger E. D., and Garner C. C. (1996) SAP102, a novel postsynaptic protein that interacts with NMDA receptor complexes in vivo. Neuron 17, 255-265.
36. Nagano T., Jourdi H., and Nawa H. (1998) Emerging roles of Dlg-like PDZ proteins in the organization of the NMDA-type glutamatergic synapse. J. Biochem. (Tokyo) 124, 869-875.
37. Neithammer M., Kim E., and Sheng M. (1996) Interaction between the C-terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases. J. Neurosci. 16, 2157-2163.
38. Ostwald K., Hagberg H., Andine P., and Karlsson J. O. (1993) Up-regulation of calpain activity in neonatal rat brain after hypoxic-ischemia. Brain Res. 630, 289-294.
39. Petito C. K., Feldmann E., Pulsinelli W. A., and Plum F. (1987) Delayed hippocampal damage in humans following cardiorespiratory arrest. Neurology 37, 1281-1286.
40. Pulsinelli W. A. and Brierley J. B. (1979) A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10, 267-272.
41. Pulsinelli W. A., Brierley J. B., and Plum F. (1982) Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann. Neurol. 11, 491-498.
42. Roche K. W., Ly C. D., Petralia R. S., Wang Y.-X., McGee A. W., Bredt D. S., and Wenthold R. J. (1999) Postsynaptic density-93 interacts with the δ2 glutamate receptor subunit at parallel fiber synapses. J. Neurosci. 19, 3926-3934.
43. Sattler R., Xiong Z., Lu W.-Y., Hafner M., MacDonald J. F., and Tymianski M. (1999) Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science 284, 1845-1848.
44. Songyang Z., Fanning A. S., Fu C., Xu J., Marfatia S. M., Chishti A. H., Crompton A., Chan A. C., Anderson J. M., and Cantley L. C. (1997) Recognition of unique carboxyl-terminal motifs by distinct PDZ domains. Science 275, 73-77.
45. Takeuchi M., Hata Y., Hirao K., Toyoda A., Irie M., and Takai Y. (1997) SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. J. Biol. Chem. 272, 11943-11951.
46. Tezuka T., Umemori H., Akiyama T., Nakanishi S., and Yamamoto T. (1999) PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A. Biochemistry 96, 435-440.
47. + channel Kv1.4. Neuron 20, 125-134.
48. Wechsler A. and Teichberg V. I. (1998) Brain spectrin binding to the NMDA receptor is regulated by phosphorylation, calcium and calmodulin. EMBO J. 17, 3931-3939.
49. Wyszynski M., Lin J., Rao A., Nigh E., Beggs A. H., Craig A. M., and Sheng M. (1997) Competitive binding of α-actinin and calmodulin to the NMDA receptor. Nature 385, 439-442.
50. Xiaoning B., Yongqi R., Jing C., Dang S., Zhuo W., and Baudry M. (1998) Calpain-mediated regulation of NMDA receptor structure and function. Brain Res. 790, 245-253.
51. Yamada Y., Chochi Y., Takamiya K., Sobue K., and Inui M. (1999) Modulation of the channel activity of the ε2/ 1-subtype N-methyl D-aspartate receptor by PSD-95. J. Biol. Chem. 274, 6647-6652.
52. Yao I., Hata Y., Ide N., Hirao K., Deguchi M., Nishioka H., Mizoguchi A., and Takai Y. (1999) MAGUIN, a novel membrane-associated guanylate kinase-interacting protein. J. Biol. Chem. 274, 11889-11896.
53. Zhang L., Hsu J. C., Takagi N., Gurd J. W. Wallace M. C., and Eubanks J. H. (1997) Transient global ischemia alters NMDA receptor expression in rat hippocampus: correlation with decreased immunoreactive protein levels of the NR2A/2B subunits, and an altered NMDA receptor functionality. J. Neurochem. 69, 1983-1994.
54. Ziff E. B. (1997) Enlightening the postsynaptic density. Neuron 19, 1163-1174.