The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2

Genes and Development

Volumn 16, Issue 22, 2002, Pages 2946-2957

  Tedesco, Donato ^a   Lukas, Jiri ^b   Reed, Steven I ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

Author keywords

Cdk4; Cks1; P130; Proteasome; Skp2; Ubiquitin

Indexed keywords

CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR; PROTEASOME; PROTEIN P130; RECOMBINANT PROTEIN; RETINOBLASTOMA PROTEIN; S PHASE KINASE ASSOCIATED PROTEIN 2; SERINE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DEPHOSPHORYLATION; DOWN REGULATION; ENZYME ACTIVITY; GENE CONTROL; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION;

CDC2-CDC28 KINASES; CELL CYCLE; CELL CYCLE PROTEINS; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASES; CYSTEINE ENDOPEPTIDASES; FUNGAL PROTEINS; HUMANS; LIGASES; MULTIENZYME COMPLEXES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; RETINOBLASTOMA-LIKE PROTEIN P130; SACCHAROMYCES CEREVISIAE PROTEINS; SERINE; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 0037112174     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1011202     Document Type: Article

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