Targeted disruption of Skp2 results in accumulation of cyclin E and p27 (Kip1), polyploidy and centrosome overduplication

EMBO Journal

Volumn 19, Issue 9, 2000, Pages 2069-2081

  Nakayama, Keiko ^a,b   Nagahama, Hiroyasu ^a,b   Minamishima, Yohji A ^a,b   Matsumoto, Masaki ^a,b   Nakamichi, Ikuo ^a,b   Kitagawa, Kyoko ^a   Shirane, Michiko ^a,b   Tsunematsu, Ryosuke ^a,b   Tsukiyama, Tadasuke ^a,b   Ishida, Noriko ^a,b   Kitagawa, Masatoshi ^a,b   Nakayama, Kei Ichi ^a,b   Hatakeyama, Shigetsugu ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Cyclin E; F box protein; SCF complex; Skp2; Ubiquitin ligase

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN E; LIGASE; PROTEIN P27; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL GROWTH; CENTROSOME; CHROMOSOME DUPLICATION; CONTROLLED STUDY; GENE DISRUPTION; GENE TARGETING; MOUSE; MOUSE MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYPLOIDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION;

ANIMALIA;

EID: 0034595292     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.9.2069     Document Type: Article

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