메뉴 건너뛰기




Volumn 10, Issue 16, 1996, Pages 1979-1990

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

Author keywords

cdk; Cyclin; proteasome; ubiquitin

Indexed keywords

CYCLINE; PROTEASOME; UBIQUITIN;

EID: 0029957947     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.16.1979     Document Type: Article
Times cited : (423)

References (43)
  • 1
    • 0028986667 scopus 로고
    • 1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast
    • 1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast. Genes & Dev. 9: 399-409.
    • (1995) Genes & Dev. , vol.9 , pp. 399-409
    • Barral, Y.1    Jentsch, S.2    Mann, C.3
  • 2
    • 0029146930 scopus 로고
    • Signal-induced site-specific phosphorylation targets IκBα to the ubiquitm-proteasome pathway
    • Chen, Z., J. Hagler, V. Palombella, F. Melandri, D. Scherer, D. Ballard, and T. Maniatis. Signal-induced site-specific phosphorylation targets IκBα to the ubiquitm-proteasome pathway. 1995. Genes & Dev. 9: 1586-1597.
    • (1995) Genes & Dev. , vol.9 , pp. 1586-1597
    • Chen, Z.1    Hagler, J.2    Palombella, V.3    Melandri, F.4    Scherer, D.5    Ballard, D.6    Maniatis, T.7
  • 3
    • 0028018268 scopus 로고
    • The ubiquitin-proteasome proteolytic pathway
    • Ciechanover, A. 1994. The ubiquitin-proteasome proteolytic pathway. Cell 79: 13-21.
    • (1994) Cell , vol.79 , pp. 13-21
    • Ciechanover, A.1
  • 4
    • 0029664461 scopus 로고    scopus 로고
    • Requirement of p27kip1 for restriction point control of the fibroblast cell cycle
    • Coats, S., M. Flanagan, J. Nourse, and J. Roberts. 1996. Requirement of p27kip1 for restriction point control of the fibroblast cell cycle. Science 272: 877-880.
    • (1996) Science , vol.272 , pp. 877-880
    • Coats, S.1    Flanagan, M.2    Nourse, J.3    Roberts, J.4
  • 5
    • 0027240841 scopus 로고
    • The yeast cln3 protein is an unstable activator of cdc28
    • Cross, F. and C. Blake. 1993. The yeast cln3 protein is an unstable activator of cdc28. Mol. Cell. Biol.. 13: 3266-3271.
    • (1993) Mol. Cell. Biol.. , vol.13 , pp. 3266-3271
    • Cross, F.1    Blake, C.2
  • 6
    • 0029049577 scopus 로고
    • Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- And G1/S-regulatory genes
    • DeGregori, J., T. Kowalik, and J.R. Nevins. 1995. Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes. Mol. Cell. Biol.. 15: 4215-4224.
    • (1995) Mol. Cell. Biol.. , vol.15 , pp. 4215-4224
    • Degregori, J.1    Kowalik, T.2    Nevins, J.R.3
  • 7
    • 0028841492 scopus 로고
    • Make it or break it: The role of ubiquitin-dependent proteolyisis in cellular regulation
    • Deshaies, R. 1995. Make it or break it: The role of ubiquitin-dependent proteolyisis in cellular regulation. Trends Cell Biol.. 5: 428-434.
    • (1995) Trends Cell Biol.. , vol.5 , pp. 428-434
    • Deshaies, R.1
  • 8
    • 0028985013 scopus 로고
    • Ubiquitination of the G1 cyclin Cln2p by a cdc34p-dependent pathway
    • Deshaies, R., V. Chau, and M. Kirschner. 1995. Ubiquitination of the G1 cyclin Cln2p by a cdc34p-dependent pathway. EMBO J.. 14: 303-312.
    • (1995) EMBO J.. , vol.14 , pp. 303-312
    • Deshaies, R.1    Chau, V.2    Kirschner, M.3
  • 9
    • 0026698263 scopus 로고
    • Association of human cyclin E with a periodic G1-S phase protein kinase
    • Dulic, V., E. Lees, and S. Reed. 1992. Association of human cyclin E with a periodic G1-S phase protein kinase. Science 257: 1958-1961.
    • (1992) Science , vol.257 , pp. 1958-1961
    • Dulic, V.1    Lees, E.2    Reed, S.3
  • 10
    • 0028980858 scopus 로고
    • Developmental control of the G1 to S transition in Drosophila: Cyclin E is a limiting downstream target of E2F.. 1995
    • Duronio, R. and P. O'Farrell. 1995. Developmental control of the G1 to S transition in Drosophila: Cyclin E is a limiting downstream target of E2F.. 1995. Genes & Dev.. 9: 1456-1468
    • (1995) Genes & Dev.. , vol.9 , pp. 1456-1468
    • Duronio, R.1    O'Farrell, P.2
  • 12
    • 0026089183 scopus 로고
    • Cyclin is degraded by the ubiquitin pathway
    • Glotzer, M., A. Murray, and M. Kirschner. 1991. Cyclin is degraded by the ubiquitin pathway. Nature 349: 132-138.
    • (1991) Nature , vol.349 , pp. 132-138
    • Glotzer, M.1    Murray, A.2    Kirschner, M.3
  • 13
    • 0028935165 scopus 로고
    • Ubiquitin, proteasomes, and the regulation of intracellular protein degradation
    • Hochstrasser, M. 1995. Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. Curr. Opin. Cell Biol.. 7: 215-223.
    • (1995) Curr. Opin. Cell Biol.. , vol.7 , pp. 215-223
    • Hochstrasser, M.1
  • 14
  • 15
    • 0029162583 scopus 로고
    • Selective protein degradation: A journey's end within the proteasome
    • Jentsch, S. and S. Schlenker. 1995. Selective protein degradation: A journey's end within the proteasome. Cell 82: 881-884.
    • (1995) Cell , vol.82 , pp. 881-884
    • Jentsch, S.1    Schlenker, S.2
  • 16
    • 0029004815 scopus 로고
    • A 20S complex containing cdc27 and cdc 16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
    • King, R., J. Peters, S. Tugendreich, M. Rolfe, P. Hieter, and M. Kirschener. 1995. A 20S complex containing cdc27 and cdc 16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81: 279-288.
    • (1995) Cell , vol.81 , pp. 279-288
    • King, R.1    Peters, J.2    Tugendreich, S.3    Rolfe, M.4    Hieter, P.5    Kirschener, M.6
  • 17
    • 0027097609 scopus 로고
    • Identification of the domains in cyclin A required for binding to, and activation of p34cdc2 and p32cdk2 protein kinase subunits
    • Kobayashi, H., E. Stewart, R. Poon, J. Adamczewski, J. Cannon, and T. Hunt. 1992. Identification of the domains in cyclin A required for binding to, and activation of p34cdc2 and p32cdk2 protein kinase subunits. Mol. Biol. Cell 3: 1279-1294.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 1279-1294
    • Kobayashi, H.1    Stewart, E.2    Poon, R.3    Adamczewski, J.4    Cannon, J.5    Hunt, T.6
  • 18
    • 0025734356 scopus 로고
    • Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family
    • Koff, A., F. Cross, A. Fisher, J. Schumacher, K. Leguellec, M. Philippe, and J.M. Roberts. 1991. Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family. Cell 66: 1217-1228.
    • (1991) Cell , vol.66 , pp. 1217-1228
    • Koff, A.1    Cross, F.2    Fisher, A.3    Schumacher, J.4    Leguellec, K.5    Philippe, M.6    Roberts, J.M.7
  • 20
    • 0023775756 scopus 로고
    • A Chinese hamster cell cycle mutant arrested at G2 phase has a temperature-sensitive ubiquitin-activating enzyme, E1
    • Kulka, R., B. Raboy, R. Schuster, H. Parag, G. Diamond, A. Ciechanover, and M. Marcus. 1988. A Chinese hamster cell cycle mutant arrested at G2 phase has a temperature-sensitive ubiquitin-activating enzyme, E1. J. Biol. Chem.. 263: 15726-15731.
    • (1988) J. Biol. Chem.. , vol.263 , pp. 15726-15731
    • Kulka, R.1    Raboy, B.2    Schuster, R.3    Parag, H.4    Diamond, G.5    Ciechanover, A.6    Marcus, M.7
  • 21
    • 0023613953 scopus 로고
    • Rapid and efficient site-specific mutagenesis without phenotypic selection
    • Kunkel, T. A., J. Roberts, and R. Zakour. 1987. Rapid and efficient site-specific mutagenesis without phenotypic selection. Meth. Enzymol.. 154: 367-382.
    • (1987) Meth. Enzymol.. , vol.154 , pp. 367-382
    • Kunkel, T.A.1    Roberts, J.2    Zakour, R.3
  • 22
    • 0029670193 scopus 로고    scopus 로고
    • Rapid degradation of the G1 cyclin cln2 induced by CDK-dependent phosphorylation.. 1996
    • Lanker, S., M. Valdivieso, and C. Wittenberg. 1996. Rapid degradation of the G1 cyclin cln2 induced by CDK-dependent phosphorylation.. 1996. Science 271: 1597-1601.
    • (1996) Science , vol.271 , pp. 1597-1601
    • Lanker, S.1    Valdivieso, M.2    Wittenberg, C.3
  • 23
    • 0025850767 scopus 로고
    • Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast
    • Lew, D.J., V. Dulic, and S.I. Reed. 1991. Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast. Cell 66: 1197-1206.
    • (1991) Cell , vol.66 , pp. 1197-1206
    • Lew, D.J.1    Dulic, V.2    Reed, S.I.3
  • 24
    • 0025944525 scopus 로고
    • The role of SW14 and SW16 in the activity of G1 cyclins in yeast
    • Nasmyth, K. and L. Dirick. 1991. The role of SW14 and SW16 in the activity of G1 cyclins in yeast. Cell 66: 995-1013.
    • (1991) Cell , vol.66 , pp. 995-1013
    • Nasmyth, K.1    Dirick, L.2
  • 25
    • 0026049598 scopus 로고
    • Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin by SWI4, a positive regulator of G1-specific transcription
    • Ogas, J., B.J. Andrews, and I. Herskowitz. 1991. Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin by SWI4, a positive regulator of G1-specific transcription. Cell 66: 1015-1026.
    • (1991) Cell , vol.66 , pp. 1015-1026
    • Ogas, J.1    Andrews, B.J.2    Herskowitz, I.3
  • 26
    • 0027193034 scopus 로고
    • Cyclin-dependent regulation of G1 in mammalian fibroblasts
    • Ohtsubo, M. and J. Roberts. 1993. Cyclin-dependent regulation of G1 in mammalian fibroblasts. Science 259: 1908-1912.
    • (1993) Science , vol.259 , pp. 1908-1912
    • Ohtsubo, M.1    Roberts, J.2
  • 27
    • 0028909645 scopus 로고
    • Human cyclin E, a nuclear protein essential for the G1 to S phase transition
    • Ohtsubo, M., A.M. Theodoras, J. Schumacher, J.M. Roberts, and M. Pagano. 1995. Human cyclin E, a nuclear protein essential for the G1 to S phase transition. Mol. Cell. Biol.. 15(5): 2612-2524.
    • (1995) Mol. Cell. Biol.. , vol.15 , Issue.5 , pp. 2612-12524
    • Ohtsubo, M.1    Theodoras, A.M.2    Schumacher, J.3    Roberts, J.M.4    Pagano, M.5
  • 28
    • 0028176483 scopus 로고
    • Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
    • Polyak, K., M. Lee, H. Erdjument-Bromage, A. Koff, J. Roberts, P. Tempst, and J. Massague. 1994. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78: 59-66.
    • (1994) Cell , vol.78 , pp. 59-66
    • Polyak, K.1    Lee, M.2    Erdjument-Bromage, H.3    Koff, A.4    Roberts, J.5    Tempst, P.6    Massague, J.7
  • 29
    • 0028173667 scopus 로고
    • Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system
    • Resnitzky, D., M. Gossen, H. Bujard, and S. Reed. 1994. Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol. Cell. Biol.. 14: 1669-1679.
    • (1994) Mol. Cell. Biol.. , vol.14 , pp. 1669-1679
    • Resnitzky, D.1    Gossen, M.2    Bujard, H.3    Reed, S.4
  • 30
    • 0027980319 scopus 로고
    • Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
    • Rock, K., C. Gram, L. Rothstein, K. Clark, R. Stein, L. Dick, D. Hwang, and A. Goldberg. 1994. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78: 761-771.
    • (1994) Cell , vol.78 , pp. 761-771
    • Rock, K.1    Gram, C.2    Rothstein, L.3    Clark, K.4    Stein, R.5    Dick, L.6    Hwang, D.7    Goldberg, A.8
  • 31
    • 0022971952 scopus 로고
    • Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis
    • Rogers, S., R. Wells, and M. Rechsreiner. 1986. Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis. Science 234: 364-368.
    • (1986) Science , vol.234 , pp. 364-368
    • Rogers, S.1    Wells, R.2    Rechsreiner, M.3
  • 32
    • 0002496513 scopus 로고
    • Assay for β-galactosidase in extracts of mammalian cells. In
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • Sambrook, J., E. Fritsch, and T. Maniatis. 1989. Assay for β-galactosidase in extracts of mammalian cells. In Molecular Cloning, pp.. 16.66-16.67. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (1989) Molecular Cloning , pp. 1666-1667
    • Sambrook, J.1    Fritsch, E.2    Maniatis, T.3
  • 33
    • 0029923035 scopus 로고    scopus 로고
    • Linkage of replication to start by the CDK inhibitor sicl
    • Schneider, B., Y. Yang, and B. Futcher. 1996. Linkage of replication to start by the CDK inhibitor sicl. Science 272: 560-562.
    • (1996) Science , vol.272 , pp. 560-562
    • Schneider, B.1    Yang, Y.2    Futcher, B.3
  • 34
    • 0028171292 scopus 로고
    • G1 phase progression: Cycling on cue
    • Sherr, C. 1994. G1 phase progression: Cycling on cue. Cell 79: 551-555.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.1
  • 36
    • 0028006070 scopus 로고
    • Destruction of Xenopus cyclins A and B2, but not B1, requires binding to p34cdc2
    • Stewart, E., H. Kobayashi, D. Harrison, and T. Hunt. 1994. Destruction of Xenopus cyclins A and B2, but not B1, requires binding to p34cdc2. EMBO J.. 13: 584-594.
    • (1994) EMBO J.. , vol.13 , pp. 584-594
    • Stewart, E.1    Kobayashi, H.2    Harrison, D.3    Hunt, T.4
  • 37
    • 0029025606 scopus 로고
    • The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis
    • Sudakin, V., D. Ganoth, A. Dahan, H. Heller, J. Hershko F. Luca, J. Ruderman, and A. Hershko. 1995. The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol. Biol. Cell 6: 185-197.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 185-197
    • Sudakin, V.1    Ganoth, D.2    Dahan, A.3    Heller, H.4    Hershko, J.5    Luca, F.6    Ruderman, J.7    Hershko, A.8
  • 38
    • 0028027308 scopus 로고
    • Ubiquitin-dependent c-un degradation in vivo is mediated by the γ domain
    • Treier, M., L. Staszewski, and D. Bohmann. 1994. Ubiquitin-dependent c-[un degradation in vivo is mediated by the γ domain. Cell 78: 787-798.
    • (1994) Cell , vol.78 , pp. 787-798
    • Treier, M.1    Staszewski, L.2    Bohmann, D.3
  • 39
    • 0026509543 scopus 로고
    • The cln2-cdc28 kinase complex of S. cerevisiae is regulated by prote- Olysis and phosphorylation
    • Tyers, M., G. Tokiwa, R. Nash, and B. Futcher. 1992. The cln2-cdc28 kinase complex of S. cerevisiae is regulated by prote- olysis and phosphorylation. EMBO J.. 11: 1773-1784.
    • (1992) EMBO J.. , vol.11 , pp. 1773-1784
    • Tyers, M.1    Tokiwa, G.2    Nash, R.3    Futcher, B.4
  • 40
    • 0027742184 scopus 로고
    • Distinct roles for cyclin-dependent kinases in cell cycle control
    • van den Heuval, S. and E. Harlow. 1993. Distinct roles for cyclin-dependent kinases in cell cycle control. Science 262: 2050-2054.
    • (1993) Science , vol.262 , pp. 2050-2054
    • Van den Heuval, S.1    Harlow, E.2
  • 41
    • 0028086017 scopus 로고
    • Cell cycle-regulated degradation of xenopus cyclin B2 requires binding to p34cdc2
    • van der Velden, H. and V. Lohka. 1994. Cell cycle-regulated degradation of xenopus cyclin B2 requires binding to p34cdc2. Mol. Cell. Biol.. 5: 713-724.
    • (1994) Mol. Cell. Biol.. , vol.5 , pp. 713-724
    • Van der Velden, H.1    Lohka, V.2
  • 42
    • 0029737650 scopus 로고    scopus 로고
    • Activation of cyclin E/cdk2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E
    • in press
    • Won, K. and S. Reed. 1996. Activation of cyclin E/cdk2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E. EMBO J.. 15 (in press).
    • (1996) EMBO J.. , vol.15
    • Won, K.1    Reed, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.