Metalloproteinase and growth factor interactions: Do they play a role in pulmonary fibrosis?

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 283, Issue 1 27-1, 2002, Pages

  Winkler, Margaret K ^a,c   Fowlkes, John L ^a,b  

^a University of Alabama at Birmingham   (United States)

^b ARKANSAS CHILDREN S HOSPITAL   (United States)

^c ACC #504 ^*  (United States)

Author keywords

Acute respiratory distress syndrome; Bronchopulmonary dysplasia; Cytokines; Emphysema; Lung fibrosis

Indexed keywords

GROWTH FACTOR; MATRIX METALLOPROTEINASE; METALLOPROTEINASE; SOMATOMEDIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

CELL DIFFERENTIATION; CELL GROWTH; CHRONIC OBSTRUCTIVE LUNG DISEASE; CYTOKINE RELEASE; DISEASE COURSE; INFLAMMATION; LUNG ALVEOLUS CELL; LUNG EMPHYSEMA; LUNG FIBROSIS; LUNG INJURY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RESPIRATORY DISTRESS; REVIEW;

EID: 0036310631     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00489.2001     Document Type: Review

References (119)

1. Expression of insulin-like growth factor binding proteins in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis
2. Growth factors in idiopathic pulmonary fibrosis: Relative roles
3. TNF-α converting enzyme (TACE) is inhibited by TIMP-3
4. Bronchopulmonary dysplasia: A correlative study by light, scanning, and transmission electron microscopy
5. Changes in collagen turnover in early acute respiratory distress syndrome
6. Enhanced insulin-like growth factor molecules in idiopathic pulmonary fibrosis
7. Structural alterations of lung parenchyma in the adult respiratory distress syndrome
8. 1-proteinase inhibitor is a neutrophil chemoattractant after proteolytic inactivation by macrophage elastase
9. Chronic obstructive pulmonary disease
10. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
11. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination
12. Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin
13. ADAMs: Focus on the protease domain
14. Remarkable roles of proteolysis on and beyond the cell surface
15. Tissue inhibitors of metalloproteinases: Evolution, structure and function
16. Insulin-like growth factor I is a major fibroblast mitogen produced by primary cultures of human airway epithelial cells
17. Localization of the 92 kd gelatinase mRNA in squamous cell and adenocarcinomas of the lung using in situ hybridization
18. Matrix metalloproteinase inhibitor prevents acute lung injury after cardiopulmonary bypass
19. Metalloproteinase inhibition prevents acute respiratory distress syndrome
20. Matrix metalloproteinases and TIMPs: Properties and implications for the treatment of chronic obstructive pulmonary disease
21. Matrix metalloproteinases-2, -8, and-9 and TIMP-2 in tracheal aspirates from preterm infants with respiratory distress
22. Expression of insulin-like growth factors and their binding proteins by bronchoalveolar cells from children with and without interstitial lung disease
23. Role of insulin-like growth factor binding proteins in controlling IGF actions
24. Transforming growth factor-β1,-β2, and -β3 stimulate fibroblast procollagen production in vitro but are differentially expressed during bleomycin-induced lung fibrosis
25. Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury
26. Inhibition of bleomycin-induced pulmonary fibrosis in mice by the matrix metalloproteinase inhibitor batimastat
27. Comparative effects of betamethasone, cyclosporin and nedocromil sodium in acute pulmonary inflammation and metalloproteinase activities in bronchoalveolar lavage fluid from mice exposed to lipopolysaccharide
28. Modulation of airway remodeling-associated mediators by the antifibrotic compound, pirfenidone, and the matrix metalloproteinase inhibitor, batimastat, during acute lung injury in mice
29. Models for gain-of-function and loss-of-function of MMPS
30. Thrombospondin-1 is a major activator of TGF-β 1 in vivo
31. Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema
32. Localization and potential role of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 and -2 in different phases of bronchopulmonary dysplasia
33. Matrix metalloproteinase and elastase activities in LPS-induced acute lung injury in guinea pigs
34. Activation of MMP- 9 by neutrophil elastase in an in vivo model of acute lung injury
35. Elevated levels of matrix metalloproteinases in bronchoalveolar lavage fluid of emphysematous patients
36. Ventilator-induced lung injury upregulates and activates gelatinases and EMMPRIN. Attenuation by the synthetic matrix metalloproteinase inhibitor, prinomastat (ag3340)
37. Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures
38. MMPs are IGFBP-degrading proteinases: Implications for cell proliferation and tissue growth
39. Proteolysis of insulin-like growth factor binding protein-3 during rat pregnancy: A role for matrix metalloproteinases
40. Matrix metalloproteinases as insulin-like growth factor binding protein-degrading proteinases
41. Exploring the interface between metalloproteinase activity and growth factor and cytokine bioavailability
42. Localization of matrix metalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases
43. The role of intraalveolar fibrosis in the process of pulmonary structural remodeling in patients with diffuse alveolar damage
44. Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5
45. Role of matrix metalloproteinases in models of macrophage-dependent acute lung injury. Evidence for alveolar macrophage as source of proteinases
46. Matrix metalloproteinase-7-dependent release of tumor necrosis factor-α in a model of herniated disc resorption
47. Macrophage elastase is required for cigarette smoke-induced emphysema in mice
48. Immunohistochemical study of metalloproteinases and their tissue inhibitors in the lungs of patients with diffuse alveolar damage and idiopathic pulmonary fibrosis
49. Infections and the inflammatory response in acute respiratory distress syndrome
50. Prospective validation of an acute respiratory distress syndrome predictive score
51. Augmentation by eosinophils of gelatinase activity in the airway mucosa: Comparative effects as a putative mediator of epithelial injury
52. The bronchial epithelium as a key regulator of airway inflammation and remodeling in asthma
53. Localization of platelet-derived growth factor and insulin-like growth factor I in the fibrotic lung
54. Bronchial subepithelial fibrosis and expression of matrix metalloproteinase-9 in asthmatic airway inflammation
55. Cell-matrix interactions in gland development in the lung
56. Remodeling in asthma and chronic obstructive lung disease
57. Differences in interleukins-8 and tumor necrosis factor-α in induced sputum from patients with chronic obstructive pulmonary disease or asthma
58. Increased matrix metalloproteinase- 9 in the airway after allergen challenge
59. Adamalysins. A family of metzincins including TNF-α converting enzyme (TACE)
60. Role of MMP-2 in alveolar epithelial cell repair after bleomycin administration in rabbits
61. Interstitial fibrosis and growth factors
62. Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)
63. Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor β1
64. Overexpression of alveolar macrophage gelatinase B (MMP-9) in patients with idiopathic pulmonary fibrosis: Effects of steroid and immunosuppressive treatment
65. The T.N.F. TNF receptor superfamilies: Integrating mammalian biology
66. Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin
67. Pulmonary fibrosis correlates with outcome in adult respiratory distress syndrome: A study in mechanically ventilated patients
68. Insulin-like growth factor II signaling in neoplastic proliferation is blocked by transgenic expression of the metalloproteinase inhibitor TIMP-1
69. Cytokines in human lung fibrosis
70. Growth factor activity in the lung during compensatory growth after pneumonectomy evidence of a role for IGF-1
71. Matrix metalloproteinases: They're not just for matrix anymore!
72. Clinical significance of respiratory bronchiolitis on open lung biopsy and its relationship to smoking related interstitial lung disease
73. The integrin alpha v beta 6 binds and activates latent TGF beta 1: A mechanism for regulating pulmonary inflammation and fibrosis
74. Matrix metalloproteinases
75. Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1
76. Gelatinase B functions as regulator and effector in leukocyte biology
77. Lung alveolar epithelial cells synthesize interstitial collagenase and gelatinases A and B in vitro
78. Matrilysin in epithelial repair and defense
79. Matrix metalloproteinases in lung biology
80. Collagenase-1 and collagen in epidermal repair
81. Role of collagenase in mediating in vitro alveolar epithelial wound repair
82. N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) inhibits transforming growth factor-beta release and reduces migration and invasiveness of human malignant glioma cells
83. Pulmonary morphology in a multihospital collaborative extracorporeal membrane oxygenation project. I. Light microscopy
84. The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis
85. Involvement of the epidermal growth factor receptor in epithelial repair in asthma
86. Heparin-binding EGF-like growth factor
87. Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: Results of a prospective, open-label phase II study
88. Elevated levels of the IGF-binding protein protease MMP-1 in asthmatic airway smooth muscle
89. 4 induces MMP-1, which functions as an IGFBP protease in human airway smooth muscle cells
90. Fibroblasts from idiopathic pulmonary fibrosis and normal lungs differ in growth rate, apoptosis and tissue inhibitor of metalloproteinases expression
91. + T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease
92. TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes
93. Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD
94. Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
95. TIMP 1, 2, 3 and 4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment?
96. Diverse roles of macrophage matrix metalloproteinases in tissue destruction and tumor growth
97. Evolving concepts in the pathogenesis of chronic obstructive pulmonary disease
98. Dexamethasone selectively modulates basal and lipopolysaccharide-induced metalloproteinase and tissue inhibitor of metalloproteinase production by human alveolar macrophages
99. Matrix metalloproteinases: Matrix degradation and more
100. Adenovector-mediated gene transfer of active transforming growth factor-beta 1 induces prolonged severe fibrosis in rat lung
101. Matrix metalloproteinases in tumor invasion and metastasis
102. How matrix metalloproteinases regulate cell behavior
103. Proteases and antiproteases
104. Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias
105. Matrix metalloproteinase-3 releases active heparin-binding EGF-like growth factor by cleavage at a specific juxtamembrane site
106. Type I collagenases in bronchoalveolar lavage fluid from preterm babies at risk of developing chronic lung disease
107. Growth factors in the extracellular matrix
108. Increased expression of inflammatory mediators in small-airway epithelium from tobacco smokers
109. Sputum matrix metalloproteinase-9: Tissue inhibitor of metalloproteinase- 1 ratio in acute asthma
110. Characterization of insulin-like growth factor-binding protein 5-degrading proteases produced throughout murine osteoblast differentiation
111. Intratracheal aerosolization of endotoxin (LPS) in the rat: A comprehensive animal model to study adult (acute) respiratory syndrome
112. Matrix metalloproteinases: Effectors of development and normal physiology
113. Lung inflammation and fibrosis
114. Medical progress: The acute respiratory distress syndrome
115. Role of stromelysin 1 and gelatinase B in experimental acute lung injury
116. ECM cell surface proteolysis: Regulating cellular ecology
117. Expression of matrix metalloproteinase gelatinases A and B by cultured epithelial cells from human bronchial explants
118. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis
119. Measurements of matrix metalloproteinases and tissue inhibitors of metalloproteinases in blood and tissues