Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1

Journal of Cell Science

Volumn 114, Issue 1, 2001, Pages 111-118

  Noë, Veerle ^a   Fingleton, Barbara ^b   Jacobs, Kathleen ^a   Crawford, Howard C ^b   Vermeulen, Stefan ^a   Steelant, Wim ^a   Bruyneel, Erik ^a   Matrisian, Lynn M ^b   Mareel, Marc ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

E cadherin catenin complex; Ectodomain shedding; Invasion; Matrix metalloproteinase; Proteolysis

Indexed keywords

COLLAGEN TYPE 1; MATRILYSIN; METALLOPROTEINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN TYROSINE KINASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UVOMORULIN;

ANIMAL CELL; ARTICLE; CANCER INVASION; CELL AGGREGATION; CELL CULTURE; CELL STRAIN MCF 7; CELL SURFACE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; KIDNEY CELL; NONHUMAN; ONCOGENE SRC; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; SOLUBILITY;

ANIMALS; CADHERINS; CELL LINE; CELL MEMBRANE; DOGS; HUMANS; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 7; TUMOR CELLS, CULTURED;

ANIMALIA; MINK CELL FOCUS-FORMING VIRUS;

EID: 0035147313     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Arribas, J., Coodly, L., Vollmer, P., Kishimoto, T. K., Rose-John, S. and Massagué, J. (1996). Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors. J. Biol. Chem. 271, 11376-11382.
2. Banks, R. E., Porter, W. H., Whelan, P., Smith, P. H. and Selby, P. J. (1995). Soluble forms of the adhesion molecule E-cadherin in urine. J. Clin. Pathol. 48, 179-180.
3. Behrens, J., Vakaet, L., Friis, R., Winterhager, E., Van Roy F., Marcel, M. M. and Birchmeier, W. (1993). Loss of epithelial morphotype and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/β-catenin complex in cells transformed with a temperature-sensitive v-src gene. J. Cell Biol. 120, 757-766.
4. Berx, G., Cleton-Jansen, A.-M., Strumane, K., de Leeuw, W. J. F., Nollet, F., Van Roy, F. and Cornelisse, C. (1996). E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. Oncogene 13, 1919-1925.
5. Borchers, A. H., Sanders, L. A. and Bowden, G. T. (1997). Regulation of matrilysin expression in cells of squamous cell carcinoma by E-cadherin-mediated cell-cell contact. J. Cancer Res. Clin. Oncol. 123, 13-20.
6. Bracke, M. E., Vyncke, B. M., Bruyneel, E. A., Vermeulen, S. J., De Bruyne, G. K., Van Larebeke, N. A., Vleminckx, K., Van Roy, F. M. and Marcel, M. M. (1993). Insulin-like growth factor I activates the invasion suppressor function of E-cadherin in MCF-7 human mammary carcinoma cells in vitro. Br. J. Cancer 68, 282-289.
7. Bracke, M. E., Van Roy, F. M. and Marcel, M. M. (1996). The E-cadherin/catenin complex in invasion and metastasis. In Attempts to Understand Metastasis Formation (ed. I. U. Günthert and W. Birchmeier), pp. 123-161. Berlin: Springer.
8. Cabrera, N., Díaz-Rodríguez, E., Becker, E., Martín-Zanca, D. and Pandiella, A. (1996). TrkA receptor ectodomain cleavage generates a tyrosine-phosphorylated cell-associated fragment. J. Cell Biol. 132, 427-436.
9. Chambers, A. F. and Matrisian, L. M. (1997). Changing views of the role of matrix metalloproteinases in metastasis. J. Natl. Cancer Inst. 89, 1260-1270.
10. Crawford, H. C., Fingleton, B. M., Rudolph-Owen, L. A., Heppner Goss, K. J., Rubinfeld, B., Polakis, P. and Matrisian, L. M. (1999). The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors. Oncogene 18, 2883-2891.
11. Fujimori, T. and Takeichi, M. (1993). Disruption of epithelial cell-cell adhesion by exogenous expression of a mutated nonfunctional N-cadherin. Mol. Biol. Cell 4, 37-47.
12. Gofuku, J., Shiozaki, H., Doki, Y., Inoue, M., Hirao, M., Fukuchi, N. and Monden, M. (1998). Characterization of soluble E-cadherin as a disease marker in gastric cancer patients. Br. J. Cancer 78, 1095-1101.
13. Griffiths, T. R. L., Brotherick, I., Bishop, R. I., White, M. D., McKenna, D. M., Home, C. H. W., Shenton, B. K., Neal, D. E. and Mellon J. K. (1996). Cell adhesion molecules in bladder cancer: soluble serum E-cadherin correlates with predictors of recurrence. Br. J. Cancer 74, 579-584.
14. Hermiston, M. L. and Gordon, J. I. (1995a). In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death. J. Cell Biol. 129, 489-506.
15. Hermiston, M. L. and Gordon, J. I. (1995b). Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science 270, 1203-1207.
16. Herren, B., Levkau, B., Raines, E. W. and Ross, R. (1998). Cleavage of β-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases. Mol. Biol. Cell 9, 1589-1601.
17. Katayama, M., Hirai, S., Kamihagi, K., Nakagawa, K., Yasumoto, M. and Kato, I. (1994). Soluble E-cadherin fragments increased in circulation of cancer patients. Br. J. Cancer 69, 580-585.
18. Takahashi, K., Suzuki, K. and Tsukatani, Y. (1997). Induction of tyrosine phosphorylation and association of β-catenin with EGF receptor upon tryptic digestion of quiescent cells at confluence. Oncogene 15, 71-78.
19. Takeichi, M. (1991). Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251, 1451-1455.
20. Vakaet, L. Jr, Vleminckx, K., Van Roy, F. and Marcel, M. (1991). Numerical evaluation of the invasion of closely related cell lines into collagen type I gels. Invasion Metastasis 11, 249-260.
21. Vermeulen, S. J., Bruyneel, E. A., Bracke, M. E., De Bruyne, G. K., Vennekens, K. M., Vleminckx, K. L., Berx, G. J., Van Roy, F. M. and Marcel, M. M. (1995). Transition from the noninvasive to the invasive phenotype and loss of α-catenin in human colon cancer cells. Cancer Res. 55, 4722-4728.
22. Werb, Z. and Van, Y. (1998). A cellular striptease act. Science 282, 1279-1280.
23. Wheelock, M. J., Buck, C. A., Bechtol, K. B. and Damsky, C. H. (1987). Soluble 80-kDa fragment of cell-CAM 120/80 disrupts cell-cell adhesion. J. Cell. Biochem. 3-4, 187-202.
24. Willems, J., Bruyneel, E., Noë, V., Slegers, H., Zwijsen, A., Mège, R.-M. and Marcel, M. (1995). Cadherin-dependent cell aggregation is affected by decapeptide derived from rat extracellular super-oxide dismutase. FEBS Lett. 363, 289-292.
25. Wilson, C. L. and Matrisian, L. M. (1996). Matrilysin: an epithelial matrix metalloproteinase with potentially novel functions. Int. J. Cell Biol. 28, 123-136.