Role of insulin-like growth factor binding proteins in controlling IGF actions

Molecular and Cellular Endocrinology

Volumn 140, Issue 1-2, 1998, Pages 19-24

  Clemmons, David R ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Extracellular matrix; Insulin like growth factor I; Serine protease; Somatomedin

Indexed keywords

CELL SURFACE RECEPTOR; GROWTH FACTOR RECEPTOR; GROWTH HORMONE; SERINE PROTEINASE; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN BINDING PROTEIN 4; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C;

BINDING AFFINITY; CONFERENCE PAPER; CONNECTIVE TISSUE CELL; EXTRACELLULAR MATRIX; FIBROBLAST; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS REGULATION; RECEPTOR BINDING; SMOOTH MUSCLE;

ANIMALS; CONNECTIVE TISSUE CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; SERINE ENDOPEPTIDASES; SOMATOMEDINS;

EID: 0032565746     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(98)00024-0     Document Type: Conference Paper

References (32)

1. Adamo M.L., Shao Z.M., Lanau F., Chen J.C., Clemmons D.R., Roberts C.T., LeRoith D., Fontana J.A. Insulin like growth factor I (IGF-I) and retinoic acid modulation of IGF binding proteins (IGFBPs). IGFBP-2, 3 and 4 gene expression and protein secretion in a breast cancer cell line. Endocrinology. 131:1992;1858-1866.
2. Arai T., Parker A.J., Busby W.H., Clemmons D.R. Heparin, heparan sulfate, and dermatan sulfate regulate formation of the insulin-like growth factor-I and insulin-like growth factor-binding protein complexes. J. Biol. Chem. 269:1994a;20388-20393.
3. Arai T., Arai A., Busby W.H., Clemmons D.R. Glycosaminoglycans inhibit degradation of insulin-like growth factor binding protein-5. Endocrinology. 135:1994b;2358-2363.
4. Camacho-Hubner C., Busby W.H., McCusker R.H., Wright G., Clemmons D.R. Identification of the forms of insulin-like growth factor binding proteins produced by human fibroblasts and the mechanisms that regulate their secretion. J. Biol. Chem. 267:1992;11949-11956.
5. Cercek B., Fishbein M.C., Forrester J.S., Helfant R.H., Fagin J.A. Induction of insulin-like growth factor I messenger RNA in rat aorta after balloon denudation. Circ. Res. 66:1990;1755-1760.
6. Chernausek S.D., Smith C.E., Duffin K.L., Busby W.H., Wright G., Clemmons D.R. Proteolytic cleavage of insulin like growth factor binding protein-4 (IGFBP-4). J. Biol. Chem. 270:1995;11377-11382.
7. Cohick W.S., Gockerman A., Clemmons D.R. Vascular smooth muscle cells synthesize two forms of insulin-like growth factor binding proteins which are regulated differently by the insulin like growth factors. J. Cell. Physiol. 157:1993;52-60.
8. Cohick W.S., Gockerman A., Clemmons D.R. Regulation of insulin like growth factor (IGF) binding protein-2 synthesis and degradation by platelet derived growth factor and IGFs is enhanced by serum deprivation in vascular growth muscle cells. J. Cell. Physiol. 164:1995;187-196.
9. Conover C.A., Kiefer M.C. Regulation of biological effect of endogenous insulin like growth factor binding protein 5 in human osteoblast cells. J. Clin. Endocrinol. Metab. 76:1993a;1153-1159.
10. Conover C.A., Bale L.K., Clarkson J.T., Torrig O. Regulation of insulin-like growth factor binding protein-5 messenger ribonucleic acid expression and protein availability in rat osteoblasts. Endocrinology. 132:1993b;2525-2530.
11. Conover C.A., Kiefer M.C., Zapf J. Post translational regulation of insulin like growth factor binding protein 4 in normal and transformed human fibroblasts. J. Clin. Invest. 91:1993c;1129-1137.
12. Conover C.A., Durham S.K., Zapf J., Masiarz F.R., Kiefer M.C. Cleavage analysis of insulin-like growth factor (IGF)-dependent IGF-binding protein-4 proteolysis and expression of protease-resistant IGF-binding protein-4 mutants. J. Biol. Chem. 270:1995;4395-4400.
13. 2 regulates insulin-like growth factor binding protein-3 expression and synthesis in human articular chondrocytes by a cAMP dependent pathway: role of calcium and protein kinase A and C. J. Cell. Biochem. 3:1996;320-333.
14. Duan C., Hawes S., Prevette T., Clemmons D.R. Insulin like growth factor-I (IGF-I) stimulates IGF binding protein-5 synthesis through transcriptional activation of the gene in aortic smooth muscle cells. J. Biol. Chem. 271:1996;4280-4288.
15. Ernst M., Rodan G.A. Increased activity of IGF-I in osteoblastic cells in the presence of GH: positive correlation with the presence of GH induced IGFBP-3. Endocrinology. 127:1990;807-814.
16. Fowlkes J., Enghild J.J., Suzukik N., Nagase H. Matrix metalloproteases degrade insulin like growth factor binding protein-3 in dermal fibroblast cultures. J. Biol. Chem. 269:1994;25742-25746.
17. Goldstein S., Moerman E.J., Jones R.A., Baxter R.C. Insulin-like growth factor binding protein 3 accumulates to high levels in culture medium of senescent and quiescent human fibroblasts. Proc. Natl. Acad. Sci. USA. 88:1991;9680-9684.
18. Hansson H.A., Dahlin L.B., Danielsen N., Fryklund L., Nachemson A.K., Polleryd P., Rovell B., Skottner A., Lundborg G. Evidence indicating trophic importance of IGF-I in regenerating peripheral nerves. Acta Physiol. Scand. 126:1986;609-613.
19. Hansson H.A., Jennische E., Skottner A. Regenerating endothelial cells express insulin-like growth factor-I immunoreactivity after arterial injury. Cell. Tissue Res. 250:1987;499-505.
20. Imai, Y., Busby, W.H., Smith, C.E., Clark, J.B., Horvitz, G.D., Rees, C., Clemmons, D.R. Protease resistant form of insulin-like growth factor binding protein-5 is an inhibitor of insulin-like growth factor-I actions in porcine smooth muscle cells in culture. J. Clin. Invest. (in press).
21. Jennische E., Hannson H.A. Regenerating skeletal muscle cells express insulin-like growth factor I. Acta Physiol. Scand. 130:1987;327-332.
22. Jennische E., Skottner A., Hansson H.A. Dynamic changes in insulin-like growth factor I immunoreactivity correlate with repair events in rat ear after freeze-thaw injury. Exp. Mol. Pathol. 47:1987a;193-201.
23. Jennische E., Skottner A., Hansson H.A. Satellite cells express the trophic factor IGF-I in regenerating skeletal muscle. Acta Physiol. Scand. 129:1987b;9-15.
24. Jones J.I., Clemmons D.R. Insulin like growth factor and their binding proteins: biologic actions. Endocr. Rev. 16:1995;3-34.
25. Lalou C., Silve C., Rosato R., Segovia B., Binoux M. Interactions between insulin-like growth factor-I (IGF-I) and the receptor of plasminogen activators and their inhibitors in the control of IGF binding protein-3 production and proteolysis in human osteosarcoma cells. Endocrinology. 135:1994;2318-2326.
26. LeRoith D., Baserga R., Helman L., Roberts C.T. Insulin like growth factors and cancer. Ann. Intern. Med. 122:1995;54-59.
27. Mohan S., Bautista C.M., Wergedal J., Baylink D.J. Isolation of inhibitory insulin-like growth factor (IGF) binding protein from bone cell conditioned medium: A potential local regulator of IGF action. Proc. Natl. Acad. Sci. USA. 86:1989;8338-8342.
28. Nam T.J., Busby W.H., Clemmons D.R. Human fibroblasts secrete a serine protease that cleaves insulin like growth factor binding protein-5. Endocrinology. 135:1994;1385-1391.
29. Nam, T.J. Busby, W.H., Clemmons, D.R., 1996. Characterization and determination of the relative abundance of two types of IGFBP-5 proteases that are secreted by human fibroblasts. Endocrinology (in press).
30. Nam T.J., Busby W.H., Clemmons D.R. Insulin-like growth factor binding protein-5 binds to plasminogen activator inhibitor-I. Endocrinology. 138:1997;2972-2998.
31. Parker A., Gockerman A., Busby W.H., Clemmons D.R. Properties of an insulin like growth factor binding protein 4 protease that is secreted by smooth muscle cells. Endocrinology. 135:1995;2470-2476.
32. Rechler M.M. Insulin like growth factor binding proteins. Vitam. Horm. 47:1993;1-114.