Intratracheal aerosolization of endotoxin (LPS) in the rat: A comprehensive animal model to study adult (acute) respiratory distress syndrome

Experimental Lung Research

Volumn 23, Issue 4, 1997, Pages 297-316

  Van Helden, H P M ^a   Kuijpers, W C ^a   Steenvoorden, D ^a   Go, C ^a   Bruijnzeel, P L B ^a   Van Eijk, M ^b   Haagsman, H P ^b  

^a TNO   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Animal model; ARDS; Hydroxyl radical; Intratracheal LPS aerosolization; Lung injury score; Respiratory failure; Surfactant protein A; TNF

Indexed keywords

ENDOTOXIN; SURFACTANT ASSOCIATED PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT RESPIRATORY DISTRESS SYNDROME; AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; HUMORAL IMMUNITY; HYPOXEMIA; INTRATRACHEAL DRUG ADMINISTRATION; LUNG COMPLIANCE; LUNG VOLUME; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RAT; RESPIRATORY FUNCTION;

EID: 0030916383     PISSN: 01902148     EISSN: None     Source Type: Journal    
DOI: 10.3109/01902149709039228     Document Type: Article

References (60)

1. Newman JH. Sepsis and pulmonary oedema. Clin Chest Med. 1985;6:371-891.
2. Montgomery AB, Stager MA, Carrico CJ, Hudson LD. Causes of mortality in patients with the adult respiratory distress syndrome. Am Rev Respir Dis. 1985;132:485-489.
3. Goris RJA. The adult respiratory distress syndrome and multiple-organ failure. Int Care News. 1987;1:1-7.
4. Murrau JF. Mechanism of acute respiratory failure. Am Rev Respir Dis. 1977;115:1071-1078.
5. Repine JF. Scientific perspectives on adult respiratory distress syndrome. Lancet. 1992;339:466-469.
6. Neuhof H. Actions and interactions of mediator systems and mediators in the pathogenesis of ARDS and multiorgan failure. Acta Anaesthesiol Scand. 1991;35:7-14.
7. Tracy KJ, Fong Y, Hesse DG. Anti-cachectin TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature (London) 1987;330:662-664.
8. Miller AB, Singer M, Meager A, Foley NM, Rook GAW. Tumor necrosis factor in bronchopulmonary secretions of patients with adult respiratory distress syndrome. Lancet. 1989;2:712-714.
9. Roberts DJ, Davies JM, Evans CC, Bell M, Mostafa LM. Tumor necrosis factor and adult respiratory distress syndrome. Am Rev Respir Dis. 1989;135:651-658.
10. Halliwell B, Gutteridge JNC. Free Radicals in Biology and Medicine, 2d ed. Oxford, UK: Clarendon; 1989.
11. Halliwell B, Gutteridge JNC. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol. 1990;186:1-85.
12. Ferrari-Baliviera E, Mealy K, Smith RJ, Wilmore DW. Tumor necrosis factor induces respiratory distress syndrome in rats. Arch Surg. 1989;124:1400-1405.
13. Klebanoff SJ. Stimulation of neutrophils by tumor necrosis factor. J Immunol. 1986;136:4220-4225.
14. Figari S, Mori NA, Palladino MA. Regulation of neutrophil migration and superoxide production by rerombinant tumor necrosis factor-α and -β: comparison to a recombinant interferon-γ and interleukin-1α. Blood. 1987;70:979-984.
15. Berkow RL, Wang D, Larrick JW, Dodson RW, Howard TH. Enhancement of the neutrophil superoxide production by preincubation with recombinant tumor necrosis factor. J Immunol. 1987;139: 3783-3791.
16. Ferrante A, Nandoskar M, Waltz A, Goh DHB, Kowanko IC. Effects of tumor necrosis factor alpha and interleukin-1 alpha and beta on human nentrophil migration, respiratory burst and degranulation. Int Arch Allergy Appl Immunol. 1988;86:82-91.
17. Atkinson YH, Marasco WA, Lopez AF, Vadas MA. Recombinant human necrosis factor-α. Regulation of N-formylmethionylleucylphenylalanine receptor affinity and function on human neutrophils. J Clin Invest. 1988;81:759-765.
18. Rabinovici R, Feuerstein G, Neville LF. Cytokine gene and peptide regulation in lung microvascular injury: new insights on the development of adult respiratory distress syndrome. Ann NY Acad Sci. 1994;725:346-353.
19. Gregory TJ, Longmore WJ, Moxley MA. Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome. J Clin Invest. 1991;88:1976-1981.
20. Lewis JF, Jobe AH. Surfactant and the adult respiraloiy distress syndrome. Am Rev Respir Dis. 1993;147:218-233.
21. Petty TL, Silvers GW, Paul GW, Standford RE. Abnormalities in lung elastic properties and surfactant function in adult respiratory distress syndrome. Chest. 1979;75:571-574.
22. Oldham KT, Guice KS, Stetson PS, Wolfe RR. Bacteremia-induced suppression of alveolar surfactant production. J Surg Res. 1989;47:397-402.
23. Rinaldo JE, Dauber JH, Christman J, Rogers RM. Neutrophil alveolitis following endotoxemia: enhancement by previous exposure to hyperoxia. Am Rev Respir Dis. 1984;130:1065-1071.
24. Mustard RA. Cardiopulmonary responses to Pseudomonas septicmia in swine: an improved model of adult respiratory distress syndrome. Lab Anim Sci. 1989;39:37-43.
25. Hanly P, Light RB. Lung mechanics in a canine model of acute Pseudomonas pneumonia. Lung. 1987;165:305-322.
26. Wheeldon EB, Walker ME, Murphy DJ, Turner CR. Intratracheal aerosolization of endotoxin in the rat: a model of the adult respiratory distress syndrome (ARDS). Lab Anim. 1992;26:29-37.
27. Morrison DC, Ryan JL. Bacterial endotoxins and host immune responses. Adv Immunol. 1979;28: 293-450.
28. Martich CD, Boujoukos AJ, Suffredini AF. Response of man to endotoxin. Immunology. 1993;187: 403-416.
29. Bergmeyer HU, Grassl M, Walter HE. Biochemical reagents for general use. In: Bergmeyer HU, ed. Methods of Enzymatic Analysis, Vol 2, 3d ed. New York: Academic; 1983: 232-233.
30. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
31. Morgan CD, Mills KC, Lefkowitz DL, Lefkowitz SS. An improved colorimetric assay for tumor necrosis factor using WEHI-164 cells cultured on novel microtiter plates. J Immunol Methods. 1991;145:259-262.
32. Sloot WN, Gramsbergen JBP. Detection of salicylate and its hydroxylated adducts 2,3- and 2,5-dihydroxybenzoic acids as possible indices for in vivo hydroxyl radical formation in combination with catechol- and indoleamines and their metabolites in cerbrospinal fluid and brain tissue. J Neurosci Methods. 1995;60:141-149.
33. Schapira RM, Ghio AJ, Effros RM, Morrisey J, Dawson CA, Hacker AD. Hydroxyl radicals are formed in the rat lung after asbestos instillation in vivo. Am J Respir Cell Mol Biol. 1994;10:573-579.
34. Schapira RM, Ghio AJ, Effros RM, et al. Hydroxyl radical production and lung injury in the rat following silica or titanium dioxide instillition in vivo. Am J Respir Cell Mol Biol. 1995;12:220-226.
35. Haagsman HP, Hawgood S, Sargeant T, et al. The major lung surfactant protein, SP 28-36, is a calcium-dependent carbohydrate binding protein. J Biol Chem. 1987;262:13877-13880.
36. Oosterlaken-Dijksterhuis MA, Van Eijk M, Van Buel BML, Van Golde LMG, Haagsman HP. Surfactant protein composition of lamellar bodies isolated from rat lung. Biochem J. 1991;274:115-119.
37. Lendrum AC, Fraser DS, Slidders W, Henderson R. Studies on the character and staining of fibrin. J Clin Pathol. 1962;15:401-405.
38. Snapper JR, Hutchinson AA, Olgetree ML, Brigham KL. Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanaesthetized sheep. J Clin Invest. 1983;72:63-76.
39. Wiener-Kronish JP, Gates L, Albertine KH, Matthay MA. The effects of alveolar E cli endotoxin on lung endothelial permeability in anesthetized sheep. Am Rev Respir Dis. 1988;137:225(A).
40. Parsons PE, Worthen GS, Moore EE, Tate RM, Henson PM. The association of circulating endotoxin with development of the adult respiratory syndrome. Am Rev Respir Dis. 1989;40:294-301.
41. Ryan LK, Karol MH. Release of tumor necrosis factor in guinea pigs upon acute inhalation of cotton dust. Am J Respir Cell MolBiol. 1991;5:93-98.
42. Sandstrom TL, Bjermer L, Rylander R. Lipopolysaccharide (LPS) inhalation and fibronectin levels in bronchoalveolar lavage fluid. Eur Respir J. 1992;5:992-996.
43. Murray JF, Matthay MA, Luce JM, Flick MR. Pulmonary perspectives: an expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis. 1998;138:720-723.
44. Wiener-Kronish JP, Gropper MA, Matthay MA. The adult respiratory distress syndrome: definition and prognosis, pathogenesis and treatment. Br J Anaesth. 1990;65:107-129.
45. Fein A, Grossman RF, Jones JG, et al. The value of edema fluid protein measurements in patients with pulmonary edema. Am J Med. 1979;67:32-39.
46. Bachofen M, Weibel ER. Alterations of the gas exchange apparatus in adult respiratory insufficiency associated with septicemia. Am Rev Respir Dis. 1977;116:589-615.
47. White CW, Jackson JH, McMurtry IF, Repine JE. Hypoxia increases glutathione redox cycle and protects rat lungs against oxidants. J Appl Physiol. 1988;65:2607-2616.
48. Hyers TM, Tricomi SM, Dettenmeier PA, Fowler AA. Tumor necrosis factor levels in serum and bronchoalveolar lavage fluid of patients with the adult respiratory distress syndrome. Am Rev Respir Dis. 1991;144:268-271.
49. Van Nhieu JT, Misset H, Lebargy F, Carlet J, Bernaudin J. Expression of tumor necrosis factor-α gene in alveolar macrophages from patients with adult respiratory distress syndrome. Am Rev Respir Dis. 1993;147:1586-1589.
50. Mulligan MS, Varani J, Dame MK, et al. Role of endothelial-leukocyte adhesion molecule 1 (FLAM-1) in neutrophil-mediated lung injury in rats. J Clin Invest. 1991;88:1396-1406.
51. Swank DS, Moore SB. Roles of the neutrophil and other mediators in adult respiratory distress syndrome. Mayo Clin Prec. 1989;64:1118-1132.
52. Sibille Y, Reynolds HY. Macrophages and polymorphonuclear neutrophils in Lung defense and injury. Am Rev Respir Dis. 1990;141:471-501.
53. Fowler AA. The adult respiratory distress syndrome: cell populations and soluble mediators in the air spaces of patients at high risk. Am Rev Respir Dis. 1987;136:1225-1231.
54. Ghofrani HA, Rosseau S, Walmrath D, Kaddus W, Kramer A, Grimminger F. Compartmentalized lung cytokine release in response to intravascular and alveolar endotoxin challenge. Am J Physiol. 1996;270:L62-L68.
55. Boujoukos AJ, Martich GD, Supinski K, Suffredini AF. Compartmentalization of the acute cytokine response after intravenous endotoxin administration. J Appl Physiol. 1993;74:3027-3033.
56. Cockshutt AM, Weitz J, Possmayer F. Pulmonary surfactant-associated protein A enhances the surface activity of lipid extract surfactant and reverses inhibition by blood proteins in vitro. Biochemistry. 1990;29:8424-8429.
57. Yukitake K, Brown CL, Schlueter MA, Clements JA, Hawgood S. Surfactant apoprotein A modifies the inhibitory effect of plasma proteins on surfactant activity in vivo. Pediatr Res. 1995;37:21-25.
58. Clements JA. Function of the alveolar lining. Am Rev Respir Dis. 1977;115:67-71.
59. McIntosh JC, Wright JR. SP-A decreases TNFα production by LPS-activated macrophages. Appl Cardiopuhn Pathophysiol 1995;5:80-81.
60. Whitsett JA, Clark JC, Wisp JR, Pryhuber GS. Effects of TNF-α and phorbol ester on human surfactant protein and MnSOD gene transcription in vitro. Am J Physiol. 1992;262:L688-L693.