MMPs are IGFBP-degrading proteinases: Implications for cell proliferation and tissue growth

Annals of the New York Academy of Sciences

Volumn 878, Issue , 1999, Pages 696-699

  Fowlkes, John L ^a,d   Serra, Delila M ^b   Nagase, Hideaki ^c   Thrailkill, Kathryn M ^a  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; GELATINASE A; PROTEINASE; SOMATOMEDIN BINDING PROTEIN; STROMELYSIN;

CELL PROLIFERATION; CONFERENCE PAPER; HUMAN; HUMAN CELL;

EID: 0032837945     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07765.x     Document Type: Conference Paper

References (4)

1. 1. Fowlkes, J.L. 1994. Degradation of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) by a metal-dependent protease produced by human fibroblasts. Endocrine 2: 63-68.
2. 2. Fowlkes, J.L., J.J. Enghild, K. Suzuki & H. Nagase. 1994. Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures. J. Biol. Chem. 269: 25742-25746.
3. 3. Fowlkes, J.L., K.M. Thrailkill, D.M. Serra & H. Nagase. 1997. Insulin-like growth factor binding protein (IGFBP) substrate zymography: a new tool to identify and characterize IGFBP-degrading proteinases. Endocrine 7: 33-36.
4. 4. Thrailkill, K.M., L.D. Quarles, H. Nagase, K. Suzuki, D.M. Serra & J.L. Fowlkes. 1995. Characterization of insulin-like growth factor-binding protein-5-degrading proteases produced throughout murine osteoblast differentiation. Endocrinology 136: 3527-3533.