Augmentation by eosinophils of gelatinase activity in the airway mucosa: Comparative effects as a putative mediator of epithelial injury

British Journal of Pharmacology

Volumn 117, Issue 4, 1996, Pages 667-674

  Herbert, Carolyn A ^a   Arthur, Michael J P ^b   Robinson, Clive ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Airway epithelium; Eosinophils; Gelatinase A; Gelatinase B; Matrix metalloproteinases; Tissue injury; Type IV collagenases

Indexed keywords

BATIMASTAT; CALCIMYCIN; CYSTEINE PROTEINASE INHIBITOR; GELATIN; GELATINASE; HYDROGEN PEROXIDE; MANNITOL; METALLOPROTEINASE INHIBITOR; PLASMIN; SERINE PROTEINASE INHIBITOR; SERUM ALBUMIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRONCHUS INJURY; BRONCHUS MUCOSA; CHELATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; EOSINOPHIL; EPITHELIUM CELL; GUINEA PIG; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT MUCOSA;

EID: 0030032722     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15242.x     Document Type: Article

References (46)

1. AGREN, M.S. (1994). Gelatinase activity during wound healing. Br. J. Dermatol., 131, 634-640.
2. BEASLEY, R., ROCHE, W.R., ROBERTS, A.J. & HOLGATE, S.T. (1989). Cellular events in the bronchi in mild asthma after bronchial provocation. Am. Rev. Respir. Dis., 139, 806-817.
3. BOUCHER, R.C. (1980). Chemical modulation of airway epithelial permeability. Env. Health Perspect., 35, 3-12.
4. CARROLL, N., ELLIOT, J., MORTON, A. & JAMES, A. (1993). The structure of large and small airways in nonfatal and fatal asthma. Am. Rev. Respir. Dis., 147, 405-410.
5. 14C] acetylated collagen. Anal. Biochem., 99, 340-345.
6. CRABBE, T., O'CONNELL, J.P., SMITH, B.J. & DOCHERTY, A.J. (1994a). Reciprocated matrix metalloproteinase activation: a process performed by interstitial collagenase and progelatinase A. Biochemistry, 33, 14419-14425.
7. CRABBE, T., SMITH, B., O'CONNELL, J. & DOCHERTY, A. (1994b). Human progelatinase A can be activated by matrilysin. FEBS Lett., 345, 14-16.
8. DJUKANOVIC, R., WILSON, J.W., BRITTEN, K.M., WILSON, S.J., WALLS, A.F., ROCHE, W.R., HOWARTH, P.H. & HOLGATE, S.T. (1990). Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry. Am. Rev. Respir. Dis., 142, 863-871.
9. DUNNILL, M.S., MASSARELLA, G.R. & ANDERSON, J.R. (1969). A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema. Thorax, 24, 176-179.
10. EMONARD, C. & GRIMAUD, J-A. (1990). Matrix metalloproteinases. A review. Cell. Mol. Biol., 36, 131-153.
11. FILLEY, W.V., HOLLEY, K.E., KEPHART, G.M. & GLEICH, G.J. (1982). Identification by immunofluorescence of eosinophil granule major basic protein in lung tissue of patients with bronchial asthma. Lancet, ii, 11-16.
12. HE, C., WILHELM, S.M., PENTLAND, A.P., MARMER B.L., GRANT, G.A., EISEN, A.Z. & GOLDBERG, G.I. (1989). Tissue co-operation in a proteolytic cascade activating human interstitial collagenase. Proc. Natl. Acad. Sci. U.S.A., 86, 2632-2636.
13. HERBERT, C.A., EDWARDS, D., BOOT, J.R. & ROBINSON, C. (1991). In vitro modulation of the eosinophil-dependent enhancement of the permeability of the bronchial mucosa. Br. J. Pharmacol., 104, 391-398.
14. HERBERT, C.A., EDWARDS, D., BOOT, J.R. & ROBINSON, C. (1993). Stimulated eosinophils and proteinases augment the transepithelial flux of albumin in bovine bronchial mucosa. Br. J. Pharmacol., 110, 840-846.
15. HERBERT, C.A., KING, C.M., RING, P.C., HOLGATE, ST., STEWART, G.A., THOMPSON, P.J. & ROBINSON, C. (1995). Augmentation of permeability in the bronchial epithelium by the house dust mite allergen Der p 1. Am. J. Respir. Cell Mol. Biol., 12, 369-378.
16. HERBERT, C.A., OMARI, T.I., SPARROW, M.P. & ROBINSON, C. (1994). Human eosinophils and recombinant matrix metalloproteinase-2 increase permeability of the bovine and porcine bronchial mucosa. Br. J. Pharmacol., 112, 461P.
17. HERBERT, C.A. & ROBINSON, C. (1995). Do gelatinases contribute to loss of epithelial cohesion in eosinophil-mediated injury of the bronchial mucosa? Br. J. Pharmacol., 115, 13P.
18. HIPPS, D.S., HEMBRY, R.H., DOCHERTY, A.J.P., REYNOLDS, J.J. & MURPHY, G. (1991), Purification and characterization of human 72kDa gelatinase (type IV collagenase). Use of immunolocalization to demonstrate the non-co-ordinate regulation of the 72kDa and 95kDa gelatinases by human fibroblasts. Biol. Chem. Hoppe Seyler, 372, 287-296.
19. HOWARTH, D., PRITZKER, K.P.H., CRUZ, T.F. & KANDEL, R.A. (1993). Calcium ionophore A23187 stimulates production of a 144kDa gelatinase. J. Rheumatol., 20, 97-101.
20. JEFFERY, P.K., WARDLAW, A.J., NELSON, F.C., COLLINS, J.V. & KAY, A.B. (1989). Bronchial biopsies in asthma. An ultrastructural, quantitative study and correlation with hyperreactivity. Am. Rev. Respir. Dis., 140, 1745-1753.
21. KOLKENBROCK, H., ORGEL, D., HECKER-KIA, A., NOACK, W. & ULBRICH, N. (1991). The complex between a tissue inhibitor of metalloproteinases (TIMP-2) and 72kDa progelatinase is a metalloproteinase inhibitor. Eur. J. Biochem., 198, 775-781.
22. r 95,000 type IV collagenase/gelatinase and interstitial fibroblast-type collagenase by rat mucosal keratinocytes. J. Biol. Chem., 268, 19143-19151.
23. MONTEFORT, S., HERBERT, C.A., ROBINSON, C. & HOLGATE, S.T. (1992). The bronchial epithelium as a target for inflammatory attack in asthma. Clin. Exp. Allergy, 22, 511-520.
24. MOTOJIMA, S., FRIGAS, E., LOEGERING, D.A. & GLEICH, G.J. (1989). Toxicity of eosinophil cationic proteins for guinea pig tracheal epithelium in vitro. Am. Rev. Respir. Dis., 139, 801-805.
25. MULLIGAN, M.S., DESROCHES, P.E., CHINNAIYAN, A.M., GIBBS, D.F., VARANI, J., JOHNSON, K.J. & WEISS, S.J. (1993). In vivo suppression of immune complex-induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinases 2. Proc. Natl. Acad. Sci. U.S.A., 90, 11523-11527.
26. r forms. J. Cell Sci., 92, 487-495.
27. MURPHY, G., REYNOLDS, J.J., BRETZ, U. & BAGGIOLINI, M. (1982). Partial purification of collagenase and gelatinase from human polymorphonuclear leucocytes. Analyses of their actions on soluble and insoluble collagens. Biochem. J., 203, 209-221.
28. OMARI, T.I., SPARROW, M.P., CHURCH, M.K., HOLGATE, S.T. & ROBINSON, C. (1993). A comparison of the effects of polyarginine and stimulated eosinophils on the responsiveness of the bovine isovolumic bronchial segment preparation. Br. J. Pharmacol., 109, 553-561.
29. D'ORTHO, M.P., JARREAU, P.H., DELACOURT, C., MACQUINMAVIER, I., LEVAME, M., PEZET, S., HARF, A. & LAFUMA, C. (1994). Matrix metalloproteinase and elastase activities in LPS-induced acute lung injury in guinea pigs. Am. J. Physiol., 266, L209-216.
30. PINCUS, S.H. (1978). Production of eosinophil-rich guinea pig peritoneal exudates. Blood, 52, 127-135.
31. RENNARD, S.I., BECKMANN, J.D. & ROBBINS, R.A. (1991). Biology of airway epithelial cells. In The Lung: Scientific Foundations, ed. Crystal, R.G., West, J.B., Barnes, P.J., Cherniak, N.S. & Weibel, E.R. pp. 157-167. New York: Raven Press.
32. ROBINSON, C. (1995). The airway epithelium as a target for inflammatory attack in asthma. In Immunopharmacology of the Respiratory Tract. ed. Holgate, S.T. London: Academic Press, (in press).
33. SALO, T., MAKELA, M., KYLMANIEMI, M., AUTIO-HARMAINEN, H. & LARJAVA, H. (1994). Expression of matrix metalloproteinase-2 and -9 during early human wound healing. Lab. Invest., 70, 176-182.
34. SATO, H., TAKINO, T., OKADA, Y., CAO, J., SHINAGAWA, A., YAMAMOTO, E. & SEIKI, M. (1994). A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature, 370, 61-65.
35. SEPPER, R., KONTTINEN, Y.T., SORSA, T. & KOSKI, H. (1994). Gelatinolytic and type IV collagenolytic activity in bronchiectasis. Chest, 106, 1129-1133.
36. SHAPIRO, S.D. (1994). Elastolytic metalloproteinases produced by human mononuclear phagocytes. Potential roles in destructive lung disease. Am. J. Resp. Crit. Care Med., 150, S160-164.
37. STEPHENS, R.J., FREEMAN, G. & EVANS, M.J. (1972). Early response of lungs to low levels of nitrogen dioxide. Arch. Environ. Health, 24, 160-179.
38. TAO, Y., BAZAN, H.E. & BAZAN, N.G. (1995). Platelet activating factor induces the expression of metalloproteinases-1 and -9, but not -2 or -3, in the corneal epithelium. Invest. Opthalmol. Vis. Sci., 36, 345-354.
39. TETLEY, T.D. (1993). Proteinase imbalance: its role in lung disease. Thorax, 48, 560-565.
40. TRIEBEL, S., BLASER, J., REINKE, H. & TSCHESCHE, H. (1992). A 25 kDa α2-microglobulin-related protein is a component of the 125 kDa form of human gelatinase. FEBS Lett., 314, 386-388.
41. TSUDA, T., KODAMA, A., YAMAMURA, M., MATSUZAKI, S. & TSUDA, M. (1993). Isolation and characterization of a high molecular weight type IV collagenase isolated from human carcinoma tissue. FEBS Lett., 319, 35-39.
42. 2-induced bronchopathy in the rat: Abnormal permeability of the bronchial epithelium in vivo and in vitro after anatomic recovery. Am. Rev. Respir. Dis., 121, 851-858.
43. VAN WART, H.E. & BIRKEDAL-HANSEN, H. (1990). The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family. Proc. Natl. Acad. Sci. U.S.A., 87, 5578-5582.
44. WARDLAW, A.J., DUNETTE, S., GLEICH, G.J., COLLINS, J.V. & KAY, A.B. (1988). Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Am. Rev. Respir. Dis., 137, 62-69.
45. WELSH, M.J., SHASBY, M. & HUSTED, R.M. (1985). Oxidants increase paracellular permeability in a cultured epithelial cell line. J. Clin. Invest., 76, 1155-1167.
46. WONG, A.P., CORTEZ, S.L. & BARICOS, W.H. (1992). Role of plasmin and gelatinase in extracellular matrix degradation by cultured rat mesangial cells. Am. J. Physiol., 263, F1112-1118.