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Volumn 1, Issue 3, 2001, Pages 211-230

Modification of alternative splicing by antisense oligonucleotides as a potential chemotherapy for cancer and other diseases

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA;

EID: 0035502474     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568009013334124     Document Type: Article
Times cited : (41)

References (183)
  • 3
    • 0035252410 scopus 로고    scopus 로고
    • Alternative Splicing: Increasing Diversity in the Proteomic World
    • Graveley, B. R. Alternative Splicing: Increasing Diversity in the Proteomic World. Trends Genet. 2001, 17, 100-107.
    • (2001) Trends Genet. , vol.17 , pp. 100-107
    • Graveley, B.R.1
  • 4
    • 0034256020 scopus 로고    scopus 로고
    • Alternative Pre-mRNA Splicing: The Logic of Combinatorial Control
    • Smith, C. W.; Valcarcel, J. Alternative Pre-mRNA Splicing: The Logic of Combinatorial Control. Trends Biochem. Sei. 2000, 25, 381-388.
    • (2000) Trends Biochem. Sei. , vol.25 , pp. 381-388
    • Smith, C.W.1    Valcarcel, J.2
  • 5
    • 33747011774 scopus 로고    scopus 로고
    • Eukaryptic mRNA Processing
    • Harnes, B. D.; Glover, D. M., Eds.; Oxford University Press: New York
    • Krainer, A. R. Eukaryptic mRNA Processing. In Frontiers in Molecular Biology; Harnes, B. D.; Glover, D. M., Eds.; Oxford University Press: New York, 1997.
    • (1997) Frontiers in Molecular Biology
    • Krainer, A.R.1
  • 6
    • 0033578006 scopus 로고    scopus 로고
    • Stage-Specific Changes in Sr Splicing Factors and Alternative Splicing in Mammary Tumorigenesis
    • Stickeier, E.; Kittrell, F.; Medina, D.; Berget, S. M. Stage-Specific Changes in Sr Splicing Factors and Alternative Splicing in Mammary Tumorigenesis. Oncogene 1999, 18, 3574-3582.
    • (1999) Oncogene , vol.18 , pp. 3574-3582
    • Stickeier, E.1    Kittrell, F.2    Medina, D.3    Berget, S.M.4
  • 7
    • 0034163539 scopus 로고    scopus 로고
    • Fibroblast Growth Factor Receptor-1 Alpha-Exon Exclusion and Polypyrimidine Tract-Binding Protein in Glioblastoma Multiforme Tumors
    • Jin, W.; McCutcheon, I. E.; Fuller, G. N.; Huang, E. S.; Cote, G. J. Fibroblast Growth Factor Receptor-1 Alpha-Exon Exclusion and Polypyrimidine Tract-Binding Protein in Glioblastoma Multiforme Tumors. Cancer Res. 2000,60, 1221-1224.
    • (2000) Cancer Res. , vol.60 , pp. 1221-1224
    • Jin, W.1    McCutcheon, I.E.2    Fuller, G.N.3    Huang, E.S.4    Cote, G.J.5
  • 8
    • 0032739144 scopus 로고    scopus 로고
    • The Interaction and Colocalization of Sam68 with the Splicing-Associated Factor YT521-B in Nuclear Dots is Regulated by the Src Family Kinase p59(fyn)
    • Hartmann, A. M.; Nayler, O.; Schwaiger, F. W.; Obermeier, A.; Stamm, S. The Interaction and Colocalization of Sam68 with the Splicing-Associated Factor YT521-B in Nuclear Dots is Regulated by the Src Family Kinase p59(fyn). Mol. Biol. Cell 1999, 10, 3909-3926.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 3909-3926
    • Hartmann, A.M.1    Nayler, O.2    Schwaiger, F.W.3    Obermeier, A.4    Stamm, S.5
  • 9
    • 0035912224 scopus 로고    scopus 로고
    • A CaMK. IV Responsive RNA Element Mediates Depolarization-Induced Alternative Splicing of Ion Channels
    • Xie, J.; Black, D. L. A CaMK. IV Responsive RNA Element Mediates Depolarization-Induced Alternative Splicing of Ion Channels. Nature 2001, 410, 936-939.
    • (2001) Nature , vol.410 , pp. 936-939
    • Xie, J.1    Black, D.L.2
  • 10
    • 0033576674 scopus 로고    scopus 로고
    • Stress-Induced Aberrant Splicing of TSG101: Association to High Tumor Grade and p53 Status in Breast Cancers
    • Turpin, E.; Dalle, B.; de Roquancourt, A.; Plassa, L. F.; Marty, M.; Janin, A.; Beuzard, Y.; de The, H. Stress-Induced Aberrant Splicing of TSG101: Association to High Tumor Grade and p53 Status in Breast Cancers. Oncogene 1999, 18, 7834-7837.
    • (1999) Oncogene , vol.18 , pp. 7834-7837
    • Turpin, E.1    Dalle, B.2    De Roquancourt, A.3    Plassa, L.F.4    Marty, M.5    Janin, A.6    Beuzard, Y.7    De The, H.8
  • 11
    • 0030854026 scopus 로고    scopus 로고
    • Aberrant Splicing but not Mutations of TSG101 in Human Breast Cancer
    • Lee, M. P.; Feinberg, A. P. Aberrant Splicing but not Mutations of TSG101 in Human Breast Cancer. Cancer Res. 1997, 57, 3131-3134.
    • (1997) Cancer Res. , vol.57 , pp. 3131-3134
    • Lee, M.P.1    Feinberg, A.P.2
  • 12
    • 0031600117 scopus 로고    scopus 로고
    • The Heparan Sulfate-Fibroblast Growth Factor Family: Diversity of Structure and Function
    • McKeehan, W. L.; Wang, F.; Kan, M. The Heparan Sulfate-Fibroblast Growth Factor Family: Diversity of Structure and Function. Prog. Nucleic Acid Res. Mol. Biol. 1998, 59, 135-376.
    • (1998) Prog. Nucleic Acid Res. Mol. Biol. , vol.59 , pp. 135-376
    • McKeehan, W.L.1    Wang, F.2    Kan, M.3
  • 14
    • 0027344852 scopus 로고
    • Structural and Functional Diversity in the FGF Receptor Multigene Family
    • Johnson, D. E.; Williams, L. T. Structural and Functional Diversity in the FGF Receptor Multigene Family. Adv. Cancer Res. 1993, 60, 1-41.
    • (1993) Adv. Cancer Res. , vol.60 , pp. 1-41
    • Johnson, D.E.1    Williams, L.T.2
  • 15
    • 0031577732 scopus 로고    scopus 로고
    • Alternative Splicing of Fibroblast Growth Factor Receptor 2 (FGF-R2) in Human Prostate Cancer
    • Carstens, R. P.; Eaton, J. V.; Krigman, H. R.; Walther, P. J.; Garcia-Blanco, M. A. Alternative Splicing of Fibroblast Growth Factor Receptor 2 (FGF-R2) in Human Prostate Cancer. Oncogene 1997,15, 3059-3065.
    • (1997) Oncogene , vol.15 , pp. 3059-3065
    • Carstens, R.P.1    Eaton, J.V.2    Krigman, H.R.3    Walther, P.J.4    Garcia-Blanco, M.A.5
  • 16
    • 0035253320 scopus 로고    scopus 로고
    • Alternative Splicing of Fibroblast Growth Factor Receptors in Human Prostate Cancer
    • Kwabi-Addo, B.; Ropiquet, F.; Giri, D.; Ittmann, M. Alternative Splicing of Fibroblast Growth Factor Receptors in Human Prostate Cancer. Prostate 2001, 46, 163-172.
    • (2001) Prostate , vol.46 , pp. 163-172
    • Kwabi-Addo, B.1    Ropiquet, F.2    Giri, D.3    Ittmann, M.4
  • 17
    • 0033835133 scopus 로고    scopus 로고
    • An Intronic Splicing Silencer Causes Skipping of the Illb Exon of Fibroblast Growth Factor Receptor 2 through Involvement of Polypyrimidine Tract Binding Protein
    • Carstens, R. P.; Wagner, E.J.; Garcia-Blanco, M.A. An Intronic Splicing Silencer Causes Skipping of the Illb Exon of Fibroblast Growth Factor Receptor 2 through Involvement of Polypyrimidine Tract Binding Protein. Mol. Cell Biol. 2000, 20, 7388-7400.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 7388-7400
    • Carstens, R.P.1    Wagner, E.J.2    Garcia-Blanco, M.A.3
  • 18
    • 0029917507 scopus 로고    scopus 로고
    • Fibroblast Growth Factor Receptor 3 is a Negative Regulator of Bone Growth
    • Deng, C.; Wynshaw-Boris, A.; Zhou, F.; Kuo, A.; Leder, P. Fibroblast Growth Factor Receptor 3 is a Negative Regulator of Bone Growth. Cell 1996, 84, 911-921.
    • (1996) Cell , vol.84 , pp. 911-921
    • Deng, C.1    Wynshaw-Boris, A.2    Zhou, F.3    Kuo, A.4    Leder, P.5
  • 19
    • 0033900046 scopus 로고    scopus 로고
    • Novel Transcripts of Fibroblast Growth Factor Receptor 3 Reveal Aberrant Splicing and Activation of Cryptic Splice Sequences in Colorectal Cancer
    • Jang, J. H.; Shin, K. H.; Park, Y. J.; Lee, R. J.; McKeehan, W. L.; Park, J. G. Novel Transcripts of Fibroblast Growth Factor Receptor 3 Reveal Aberrant Splicing and Activation of Cryptic Splice Sequences in Colorectal Cancer. Cancer Res. 2000, 60, 4049-4052.
    • (2000) Cancer Res. , vol.60 , pp. 4049-4052
    • Jang, J.H.1    Shin, K.H.2    Park, Y.J.3    Lee, R.J.4    McKeehan, W.L.5    Park, J.G.6
  • 20
    • 0034685038 scopus 로고    scopus 로고
    • Identification of a Novel Alternative Splicing of Human FGF Receptor 4: SolubleForm Splice Variant Expressed in Human Gastrointestinal Epithelial Cells
    • Takaishi, S.; Sawada, M.; Morita, Y.; Seno, H.; Fukuzawa, H.; Chiba, T. Identification of a Novel Alternative Splicing of Human FGF Receptor 4: SolubleForm Splice Variant Expressed in Human Gastrointestinal Epithelial Cells. Biochem. Biophys. Res. Commun. 2000, 267, 658-662.
    • (2000) Biochem. Biophys. Res. Commun. , vol.267 , pp. 658-662
    • Takaishi, S.1    Sawada, M.2    Morita, Y.3    Seno, H.4    Fukuzawa, H.5    Chiba, T.6
  • 21
    • 0035835816 scopus 로고    scopus 로고
    • Wilms Tumor and the WT1 Gene
    • Lee, S. B.; Haber, D. A. Wilms Tumor and the WT1 Gene. Exp. Cell Res. 2001, 264, 74-99.
    • (2001) Exp. Cell Res. , vol.264 , pp. 74-99
    • Lee, S.B.1    Haber, D.A.2
  • 24
    • 0033561499 scopus 로고    scopus 로고
    • Analysis of Native WTI Protein from Frozen Human Kidney and Wilms1 Tumors
    • Iben, S.; Royer-Pokora, B. Analysis of Native WTI Protein from Frozen Human Kidney and Wilms1 Tumors. Oncogene 1999, 18, 2533-2536.
    • (1999) Oncogene , vol.18 , pp. 2533-2536
    • Iben, S.1    Royer-Pokora, B.2
  • 25
    • 0035252110 scopus 로고    scopus 로고
    • Par4 is a Coactivator for a Splice IsoformSpecific Transcriptional Activation Domain in WTI
    • Richard, D.J.; Schumacher, V.; Royer-Pokora, B.; Roberts, S. G. Par4 is a Coactivator for a Splice IsoformSpecific Transcriptional Activation Domain in WTI. Genes Dey. 2001, 15, 328-339.
    • (2001) Genes Dey. , vol.15 , pp. 328-339
    • Richard, D.J.1    Schumacher, V.2    Royer-Pokora, B.3    Roberts, S.G.4
  • 26
    • 0032548827 scopus 로고    scopus 로고
    • BRCA1, BRCA2, and DNA Damage Response: Collision or Collusion?
    • Zhang, H.; Tombline, G.; Weber, B.L. BRCA1, BRCA2, and DNA Damage Response: Collision or Collusion? Cell 1998, 92, 433-436.
    • (1998) Cell , vol.92 , pp. 433-436
    • Zhang, H.1    Tombline, G.2    Weber, B.L.3
  • 27
    • 0029795422 scopus 로고    scopus 로고
    • Characterization of Functional Messenger RNA Splice Variants of BRCA1 Expressed in Nonmalignant and Tumor-Derived Breast Cells
    • Lu, M.; Conzen, S. D.; Cole, C. N.; Arrick, B. A. Characterization of Functional Messenger RNA Splice Variants of BRCA1 Expressed in Nonmalignant and Tumor-Derived Breast Cells. Cancer Res. 1996, 56, 4578-4581.
    • (1996) Cancer Res. , vol.56 , pp. 4578-4581
    • Lu, M.1    Conzen, S.D.2    Cole, C.N.3    Arrick, B.A.4
  • 30
    • 0034816781 scopus 로고    scopus 로고
    • Expression Profiles of BRCA1 Splice Variants in Asynchronous and in Gl/S Synchronized Tumor Cell Lines
    • Orban, T. I.; Olah, E. Expression Profiles of BRCA1 Splice Variants in Asynchronous and in Gl/S Synchronized Tumor Cell Lines. Biochem. Biophys. Res. Commun. 2001, 250, 32-38.
    • (2001) Biochem. Biophys. Res. Commun. , vol.250 , pp. 32-38
    • Orban, T.I.1    Olah, E.2
  • 31
    • 0033152121 scopus 로고    scopus 로고
    • Increased Level of Exon 12 Alternatively Spliced BRCA2 Transcripts in Tumor Breast Tissue Compared with Normal Tissue
    • Bieche, I.; Lidereau, R. Increased Level of Exon 12 Alternatively Spliced BRCA2 Transcripts in Tumor Breast Tissue Compared with Normal Tissue. Cancer Res. 1999, 59, 2546-2550.
    • (1999) Cancer Res. , vol.59 , pp. 2546-2550
    • Bieche, I.1    Lidereau, R.2
  • 32
    • 0001873478 scopus 로고    scopus 로고
    • Molecular Studies into the Role of CD44 Variants in Metastasis in Gastric Cancer
    • Hsieh, H. F.; Yu, J. C.; Ho, L. I.; Chiu, S. C.; Harn, H. J. Molecular Studies into the Role of CD44 Variants in Metastasis in Gastric Cancer. Mol. Pathol. 1999, 52, 2528.
    • (1999) Mol. Pathol. , vol.52 , pp. 2528
    • Hsieh, H.F.1    Yu, J.C.2    Ho, L.I.3    Chiu, S.C.4    Harn, H.J.5
  • 33
    • 0031874645 scopus 로고    scopus 로고
    • The Normal Structure and Function of CD44 and its Role in Neoplasia
    • Sneath, R. J.; Mangham, D. C. The Normal Structure And Function Of CD44 and its Role in Neoplasia. Mol. Pathol. 1998, 51, 191-200.
    • (1998) Mol. Pathol. , vol.51 , pp. 191-200
    • Sneath, R.J.1    Mangham, D.C.2
  • 34
    • 0034013966 scopus 로고    scopus 로고
    • The CD44 Receptor of the Mouse LB T-Cell Lymphoma: Analysis of the Isoform Repertoire and Ligand Binding Properties by Reverse-Transcriptase Polymerase Chain Reaction and Antisense Oligonucleotides
    • Wallach, S. B.; Friedmann, A.; Naor, D. The CD44 Receptor of the Mouse LB T-Cell Lymphoma: Analysis of the Isoform Repertoire and Ligand Binding Properties by Reverse-Transcriptase Polymerase Chain Reaction and Antisense Oligonucleotides. Cancer Detect. Prev. 2000. 24, 33-45.
    • (2000) Cancer Detect. Prev. , vol.24 , pp. 33-45
    • Wallach, S.B.1    Friedmann, A.2    Naor, D.3
  • 35
    • 0032791736 scopus 로고    scopus 로고
    • Adhesion Proteins in the Biology of Breast Cancer: Contribution of CD44
    • Herrera-Gayol, A.; Jothy, S. Adhesion Proteins in the Biology of Breast Cancer: Contribution of CD44. Exp. Mol. Pathol. 1999, 66, 149-156.
    • (1999) Exp. Mol. Pathol. , vol.66 , pp. 149-156
    • Herrera-Gayol, A.1    Jothy, S.2
  • 37
    • 0035312291 scopus 로고    scopus 로고
    • The Human XPG Gene: Gene Architecture, Alternative Splicing and Single Nucleotide Polymorphisms
    • Emmert, S.; Schneider, T. D.; Khan, S. G.; Kraemer, K. H. The Human XPG Gene: Gene Architecture, Alternative Splicing and Single Nucleotide Polymorphisms. Nucleic Acids Res. 2001, 29, 1443-1452.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 1443-1452
    • Emmert, S.1    Schneider, T.D.2    Khan, S.G.3    Kraemer, K.H.4
  • 38
    • 0033854786 scopus 로고    scopus 로고
    • Reduced Expression Levels of Nucleotide Excision Repair Genes in Lung Cancer: A Case-Control Analysis
    • Cheng, L.; Spitz, M. R.; Hong, W. K.; Wei, Q. Reduced Expression Levels of Nucleotide Excision Repair Genes in Lung Cancer: A Case-Control Analysis. Carcinogenesis 2000, 21, 1527-1530.
    • (2000) Carcinogenesis , vol.21 , pp. 1527-1530
    • Cheng, L.1    Spitz, M.R.2    Hong, W.K.3    Wei, Q.4
  • 39
    • 0029832418 scopus 로고    scopus 로고
    • Reduced DNA Repair Capacity in Lung Cancer Patients
    • Wei, Q.; Cheng, L.; Hong, W. K.; Spitz, M. R. Reduced DNA Repair Capacity in Lung Cancer Patients. Cancer Res. 1996, 56, 4103-4107.
    • (1996) Cancer Res. , vol.56 , pp. 4103-4107
    • Wei, Q.1    Cheng, L.2    Hong, W.K.3    Spitz, M.R.4
  • 41
    • 0033522881 scopus 로고    scopus 로고
    • BrainDerived Neurotrophic Factor Promotes Survival and Chemoprotection of Human Neuroblastoma Cells
    • .Middlemas, D. S.; Kihl, B. K.; Zhou, J.; Zhu, X. BrainDerived Neurotrophic Factor Promotes Survival and Chemoprotection of Human Neuroblastoma Cells. J. Biol. Chem. 1999, 274, 16451-16460.
    • (1999) J. Biol. Chem. , vol.274 , pp. 16451-16460
    • Middlemas, D.S.1    Kihl, B.K.2    Zhou, J.3    Zhu, X.4
  • 42
    • 0035836071 scopus 로고    scopus 로고
    • Human Neuroblastomas with Unfavorable Biologies Express High Levels of BrainDerived Neurotrophic Factor mRNA and a Variety of its Variants
    • Aoyama, M.; Asai, K.; Shishikura, T.; Kawamoto, T.; Miyachi, T.; Yokoi, T.; Togari, H.; Wada, Y.; Kato, T.; Nakagawara, A. Human Neuroblastomas with Unfavorable Biologies Express High Levels of BrainDerived Neurotrophic Factor mRNA and a Variety of its Variants. Cancer Lett. 2001,164, 51-60. .
    • (2001) Cancer Lett. , vol.164 , pp. 51-60
    • Aoyama, M.1    Asai, K.2    Shishikura, T.3    Kawamoto, T.4    Miyachi, T.5    Yokoi, T.6    Togari, H.7    Wada, Y.8    Kato, T.9    Nakagawara, A.10
  • 43
    • 0032914182 scopus 로고    scopus 로고
    • Alternative Splicing and Programmed Cell Death
    • Jiang, Z. H.; Wu, J. Y. Alternative Splicing and Programmed Cell Death. Proc. Soc. Exp. Biol. Med. 1999, 220, 64-72.
    • (1999) Proc. Soc. Exp. Biol. Med. , vol.220 , pp. 64-72
    • Jiang, Z.H.1    Wu, J.Y.2
  • 44
    • 0028168593 scopus 로고
    • Ich1, an Ice/ced-3-Related Gene, Encodes both Positive and Negative Regulators of Programmed Cell Death
    • Wang, L.; Miura, M.; Bergeron, L.; Zhu, H.; Yuan, J. Ich1, an Ice/ced-3-Related Gene, Encodes both Positive and Negative Regulators of Programmed Cell Death. Cell 1994, 78, 739-750.
    • (1994) Cell , vol.78 , pp. 739-750
    • Wang, L.1    Miura, M.2    Bergeron, L.3    Zhu, H.4    Yuan, J.5
  • 45
    • 0033024272 scopus 로고    scopus 로고
    • Up-regulation of ICH1L Protein by Thromboxane A2 Antagonists Enhances Cisplatin-Induced Apoptosis in Non-Small-Cell LungCancer Cell Lines
    • Fujimura, M.; Kasahara, K.; Shirasaki, H.; Heki, U.; Iwasa, K.; Ueda, A.; Matsuda, T. Up-regulation of ICH1L Protein by Thromboxane A2 Antagonists Enhances Cisplatin-Induced Apoptosis in Non-Small-Cell LungCancer Cell Lines. J. Cancer Res. Clin. Oncol. 1999, 725, 389-394.
    • (1999) J. Cancer Res. Clin. Oncol. , vol.725 , pp. 389-394
    • Fujimura, M.1    Kasahara, K.2    Shirasaki, H.3    Heki, U.4    Iwasa, K.5    Ueda, A.6    Matsuda, T.7
  • 46
    • 0035843138 scopus 로고    scopus 로고
    • Modulation of Apoptosis by Procaspase-2 Short Isoform: Selective Inhibition of Chromatin Condensation, Apoptotic Body Formation and Phosphatidylserine Externalization
    • Droin, N.; Rebe, C.; Bichat, F.; Hammann, A.; Bertrand, R.; Solary, E. Modulation of Apoptosis By Procaspase-2 Short Isoform: Selective Inhibition of Chromatin Condensation, Apoptotic Body Formation and Phosphatidylserine Externalization. Oncogens 2001, 20, 260-269.
    • (2001) Oncogens , vol.20 , pp. 260-269
    • Droin, N.1    Rebe, C.2    Bichat, F.3    Hammann, A.4    Bertrand, R.5    Solary, E.6
  • 47
    • 0023786047 scopus 로고
    • Bcl-2 Gene Promotes Haemopoietic Cell Survival and Cooperates with C-Myc to Immortalize Pre-B Cells
    • Vaux, D. L.; Cory, S.; Adams, J. M. Bcl-2 Gene Promotes Haemopoietic Cell Survival and Cooperates With C-Myc to Immortalize Pre-B Cells. Nature 1988, 335, 440-442.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 48
    • 0032998309 scopus 로고    scopus 로고
    • Overcoming Bcl-2- And p53-Mediated Resistance in Prostate Cancer
    • DiPaola, R. S.; Aisner, J. Overcoming Bcl-2- and p53-Mediated Resistance in Prostate Cancer. Semin. Oncol. 1999,26, 112-116.
    • (1999) Semin. Oncol. , vol.26 , pp. 112-116
    • Dipaola, R.S.1    Aisner, J.2
  • 49
    • 0033913693 scopus 로고    scopus 로고
    • Shanahan, F. Altered Mechanisms of Apoptosis in Colon Cancer: Fas Resistance and Counterattack in the Tumor-Immune Conflict
    • discussion 193-195
    • O'Connell, J.; Bennett, M. W.; Nally, K.; Houston, A.; O'Sullivan, G. C.; Shanahan, F. Altered Mechanisms of Apoptosis in Colon Cancer: Fas Resistance and Counterattack in the Tumor-Immune Conflict. Ann. N. Y. Acad. Sei. 2000, 910, 178-192; discussion 193-195.
    • (2000) Ann. N. Y. Acad. Sei. , vol.910 , pp. 178-192
    • O'Connell, J.1    Bennett, M.W.2    Nally, K.3    Houston, A.4    O'Sullivan, G.C.5
  • 50
    • 0022546957 scopus 로고
    • Analysis of the Structure, Transcripts, and Protein Products of Bcl-2, the Gene Involved in Human Follicular Lymphoma
    • Tsujimoto, Y.; Croce, C. M. Analysis of the Structure, Transcripts, and Protein Products of Bcl-2, The Gene Involved in Human Follicular Lymphoma. Proc. Natl. Acad. Sei. U. S. A. 1986, 83, 5214-5218.
    • (1986) Proc. Natl. Acad. Sei. U. S. A. , vol.83 , pp. 5214-5218
    • Tsujimoto, Y.1    Croce, C.M.2
  • 51
    • 0032719052 scopus 로고    scopus 로고
    • Tamoxifen-Induced Apoptosis in Breast Cancer Cells Relates to Down- Regulation of Bcl-2, but not Bax and Bcl-x(L), without Alteration of p53 Protein Levels
    • Zhang, G. J.; Kimijima, I.; Onda, M.; Kanno, M.; Sato, H.; Watanabe, T.; Tsuchiya, A.; Abe, R.; Takenoshita, S. Tamoxifen-Induced Apoptosis in Breast Cancer Cells Relates to Down- Regulation of Bcl-2, but not Bax and Bcl-x(L), without Alteration of p53 Protein Levels. Clin. Cancer Res. 1999,5, 2971-2977.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2971-2977
    • Zhang, G.J.1    Kimijima, I.2    Onda, M.3    Kanno, M.4    Sato, H.5    Watanabe, T.6    Tsuchiya, A.7    Abe, R.8    Takenoshita, S.9
  • 56
    • 0030795866 scopus 로고    scopus 로고
    • Bcl-2 and BclxL can Differentially Block Chemotherapy-Induced Cell Death
    • Simonian, P. L.; Grillot, D. A.; Nunez, G. Bcl-2 and BclxL can Differentially Block Chemotherapy-Induced Cell Death. Blood 1997, 90, 1208-1216.
    • (1997) Blood , vol.90 , pp. 1208-1216
    • Simonian, P.L.1    Grillot, D.A.2    Nunez, G.3
  • 58
    • 0033526938 scopus 로고    scopus 로고
    • Inhibition of Bcl-xL Expression Sensitizes Normal Human Keratinocytes and Epithelial Cells to Apoptotic Stimuli
    • Taylor, J. K.; Zhang, Q. Q.; Monia, B. P.; Marcusson, E. G.; Dean, N. M. Inhibition of Bcl-xL Expression Sensitizes Normal Human Keratinocytes and Epithelial Cells to Apoptotic Stimuli. Oncogene 1999,18, 4495-4504.
    • (1999) Oncogene , vol.18 , pp. 4495-4504
    • Taylor, J.K.1    Zhang, Q.Q.2    Monia, B.P.3    Marcusson, E.G.4    Dean, N.M.5
  • 59
    • 0028979438 scopus 로고
    • Overexpression of Bcl-XS Sensitizes MCF-7 Cells to Chemotherapy-Induced Apoptosis
    • Sumantran, V. N.; Ealovega, M. W.; Nunez, G.; Clarke, M. F.; Wicha, M. S. Overexpression of Bcl-XS Sensitizes MCF-7 Cells to Chemotherapy-Induced Apoptosis. Cancer Res. 1995,55, 2507-2510.
    • (1995) Cancer Res. , vol.55 , pp. 2507-2510
    • Sumantran, V.N.1    Ealovega, M.W.2    Nunez, G.3    Clarke, M.F.4    Wicha, M.S.5
  • 60
    • 0029852727 scopus 로고    scopus 로고
    • Enforced Expression of Bcl-XS Induces Differentiation and Sensitizes Chronic Myelogenous Leukemia-Blast Crisis K562 Cells to 1-Beta-D-Arabinofuranosylcytosine-Mediated Differentiation and Apoptosis
    • Ray, S.; Bullock, G.; Nunez, G.; Tang, C.; Ibrado, A. M.; Huang, Y.; Bhalla, K. Enforced Expression of Bcl-XS Induces Differentiation and Sensitizes Chronic Myelogenous Leukemia-Blast Crisis K562 Cells to 1-Beta-D-Arabinofuranosylcytosine-Mediated Differentiation and Apoptosis. Cell Growth Differ. 1996, 7, 1617-1623.
    • (1996) Cell Growth Differ. , vol.7 , pp. 1617-1623
    • Ray, S.1    Bullock, G.2    Nunez, G.3    Tang, C.4    Ibrado, A.M.5    Huang, Y.6    Bhalla, K.7
  • 62
    • 0027166048 scopus 로고
    • Bcl-2 Heterodimerizes in Vivo with A Conserved Homolog, Bax, that Accelerates Programmed Cell Death
    • Oltvai, Z. N.; Milliman, C. L.; Korsmeyer, S. J. Bcl-2 Heterodimerizes In Vivo With A Conserved Homolog, Bax, that Accelerates Programmed Cell Death. Cell 1993, 74, 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 63
    • 0034074374 scopus 로고    scopus 로고
    • Significance of Apoptosis and Apoptotic-Related Proteins, Bcl-2, and Bax in Primary Breast Cancer
    • VVu, J.; Shao, Z. M.; Shen, Z. Z.; Lu, J.S.; Han, Q. X.; Fontana, J. A.; Barsky, S. H. Significance of Apoptosis and Apoptotic-Related Proteins, Bcl-2, and Bax in Primary Breast Cancer. Breast J. 2000, 6, 44-52.
    • (2000) Breast J. , vol.6 , pp. 44-52
    • Vvu, J.1    Shao, Z.M.2    Shen, Z.Z.3    Lu, J.S.4    Han, Q.X.5    Fontana, J.A.6    Barsky, S.H.7
  • 64
    • 0032496238 scopus 로고    scopus 로고
    • A Novel Splice Variant of the Cell Death-Promoting Protein BAX
    • Zhou, M.; Demo, S. D.; McClure, T. N.; Crea, R.; Bitler, C. M. A Novel Splice Variant of the Cell Death-Promoting Protein BAX. J. Biol. Chem. 1998,273, 11930-11936.
    • (1998) J. Biol. Chem. , vol.273 , pp. 11930-11936
    • Zhou, M.1    Demo, S.D.2    McClure, T.N.3    Crea, R.4    Bitler, C.M.5
  • 65
    • 0029024368 scopus 로고
    • Mapping of the Human BAX Gene to Chromosome 19q13.3-Q13.4 and Isolation of a Novel Alternatively Spliced Transcript, BAX Delta
    • Apte, S. S.; Mattel, M. G.; Olsen, B. R. Mapping of the Human BAX Gene to Chromosome 19q13.3-Q13.4 and Isolation of a Novel Alternatively Spliced Transcript, BAX Delta Genomics 1995, 26, 592-594.
    • (1995) Genomics , vol.26 , pp. 592-594
    • Apte, S.S.1    Mattel, M.G.2    Olsen, B.R.3
  • 66
    • 0034574642 scopus 로고    scopus 로고
    • Induction of Apoptosis in Head-and-Neck Squamous Carcinoma Cells by Gamma-Irradiation and Bleomycin is p53-Independent
    • Patel, V.; Ensley, J. F.; Gutkind, J. S.; Yeudall, W. A. Induction of Apoptosis in Head-and-Neck Squamous Carcinoma Cells by Gamma-Irradiation and Bleomycin is p53-Independent. Int. J. Cancer 2000, 88, 737-743.
    • (2000) Int. J. Cancer , vol.88 , pp. 737-743
    • Patel, V.1    Ensley, J.F.2    Gutkind, J.S.3    Yeudall, W.A.4
  • 67
    • 0032055536 scopus 로고    scopus 로고
    • Gene Expression by Single Reed-Sternberg Cells: Pathways of Apoptosis and Activation
    • Messineo, C.; Jamerson, M. H.; Hunter, E.; Braziel, R.; Bagg, A.; Irving, S. G.; Cossman, J. Gene Expression by Single Reed-Sternberg Cells: Pathways of Apoptosis and Activation. Blood 1998, 91, 2443-2451.
    • (1998) Blood , vol.91 , pp. 2443-2451
    • Messineo, C.1    Jamerson, M.H.2    Hunter, E.3    Braziel, R.4    Bagg, A.5    Irving, S.G.6    Cossman, J.7
  • 72
    • 0033159536 scopus 로고    scopus 로고
    • Alternative Splicing, but not Allelic Loss, of the FHIT Gene Increases with Development of Lung Cancer
    • Sato, H.; Hiyama, K.; Ishioka, S.; Maeda, H.; Yamakido, M. Alternative Splicing, but not Allelic Loss, of the FHIT Gene Increases with Development of Lung Cancer. Int. J. Oncol. 1999, 15, 81-88.
    • (1999) Int. J. Oncol. , vol.15 , pp. 81-88
    • Sato, H.1    Hiyama, K.2    Ishioka, S.3    Maeda, H.4    Yamakido, M.5
  • 73
    • 0033552641 scopus 로고    scopus 로고
    • The p53 Gene Family
    • Kaelin, W. G., Jr. The p53 Gene Family. Oncogene 1999, 18, 7701-7705.
    • (1999) Oncogene , vol.18 , pp. 7701-7705
    • Kaelin Jr., W.G.1
  • 76
    • 0033381054 scopus 로고    scopus 로고
    • Regulation and Activation of p53 and its Family Members
    • Lohrum, M. A.; Vousden, K. H. Regulation and Activation of p53 and its Family Members. Cell Death Differ. 1999, 6, 1162-1168.
    • (1999) Cell Death Differ. , vol.6 , pp. 1162-1168
    • Lohrum, M.A.1    Vousden, K.H.2
  • 77
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 Promotes the Rapid Degradation of p53
    • Haupt, Y.; Maya, R.; Kazaz, A.; Oren, M. Mdm2 Promotes the Rapid Degradation of p53. Nature 1997, 387, 296-299.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 78
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 Stability by MDM2
    • Kubbutat, M. H.; Jones, S. N.; Vousden, K. H. Regulation of p53 Stability by MDM2. Nature 1997, 387, 299-303.
    • (1997) Nature , vol.387 , pp. 299-303
    • Kubbutat, M.H.1    Jones, S.N.2    Vousden, K.H.3
  • 80
    • 0032520061 scopus 로고    scopus 로고
    • Short Alternative Splice Transcripts of the MDM2 Oncogene Correlate to Malignancy in Human Astrocytic Neoplasms
    • Matsumoto, R.; Tada, M.; Nozaki, M.; Zhang, C. L.; Sawamura, Y.; Abe, H. Short Alternative Splice Transcripts of the MDM2 Oncogene Correlate To Malignancy in Human Astrocytic Neoplasms. Cancer Res. 1998, 58, 609-613.
    • (1998) Cancer Res. , vol.58 , pp. 609-613
    • Matsumoto, R.1    Tada, M.2    Nozaki, M.3    Zhang, C.L.4    Sawamura, Y.5    Abe, H.6
  • 81
    • 0029824669 scopus 로고    scopus 로고
    • Alternatively Spliced mdm2 Transcripts with Loss of p53 Binding Domain Sequences: Transforming Ability and Frequent Detection in Human Cancer
    • Sigalas, I.; Calvert, A. H.; Anderson, J. J.; Neal, D. E. Lunée, J. Alternatively Spliced mdm2 Transcripts with Loss of p53 Binding Domain Sequences: Transforming Ability and Frequent Detection in Human Cancer. Nat. Med.1996,2, 912-917.
    • (1996) Nat. Med. , vol.2 , pp. 912-917
    • Sigalas, I.1    Calvert, A.H.2    Anderson, J.J.3    Neal, D.E.4    Lunée, J.5
  • 82
    • 0035300512 scopus 로고    scopus 로고
    • Alternative and Aberrant Messenger RNA Splicing of the mdm2 Oncogene in Invasive Breast Cancer
    • Lukas, J.; Gao, D. Q.; Keshmeshian, M.; Wen; W. H.; Tsao-Wei, D.; Rosenberg, S.; Press, M. F. Alternative and Aberrant Messenger RNA Splicing of the mdm2 Oncogene in Invasive Breast Cancer. Cancer Res. 2001, 61, 3212-3219.
    • (2001) Cancer Res. , vol.61 , pp. 3212-3219
    • Lukas, J.1    Gao, D.Q.2    Keshmeshian, M.3    Wen, W.H.4    Tsao-Wei, D.5    Rosenberg, S.6    Press, M.F.7
  • 83
    • 1042274013 scopus 로고    scopus 로고
    • Amplification of the MDM2 gene, but not Expression of Splice Variants of MDM2 MRNA, is Associated with Prognosis in Soft Tissue Sarcoma
    • Barte!, F.; Meye, A.; Wuri, P.; Kappler, M.; Bache, M.; Lautenschlager; C.; Grunbaum, U.; Schmidt, H.; Taubert, H. Amplification of the MDM2 gene, but not Expression of Splice Variants of MDM2 MRNA, is Associated with Prognosis in Soft Tissue Sarcoma./J. J. Cancer2001, 95, 168-175.
    • (2001) /J. J. Cancer , vol.95 , pp. 168-175
    • Barte, F.1    Meye, A.2    Wuri, P.3    Kappler, M.4    Bache, M.5    Lautenschlager, C.6    Grunbaum, U.7    Schmidt, H.8    Taubert, H.9
  • 84
    • 0029953670 scopus 로고    scopus 로고
    • Multiple Enzyme Forms from a Single Gene and their Relation to Cancer
    • Keppler, D.; Sloane, B. F. Cathepsin B: Multiple Enzyme Forms from a Single Gene and their Relation to Cancer. Enzyme Protein 1996, 49, 94-105.
    • (1996) Enzyme Protein , vol.49 , pp. 94-105
    • Keppler, D.1    Sloane, B.F.2    Cathepsin, B.3
  • 86
    • 0035897568 scopus 로고    scopus 로고
    • Activity, Function, and Gene Regulation of the Catalytic Subunit ofTelomerase(hTERT)
    • Poole, J. C.; Andrews, L. G.; Tollefsbol, T. O. Activity, Function, and Gene Regulation of the Catalytic Subunit ofTelomerase(hTERT). Gene 2001, 269, 1-12.
    • (2001) Gene , vol.269 , pp. 1-12
    • Poole, J.C.1    Andrews, L.G.2    Tollefsbol, T.O.3
  • 87
    • 0034048726 scopus 로고    scopus 로고
    • Adenoviral Expression of p53 Represses Telomerase Activity through Down-Regulation of Human Telomerase Reverse Transcriptase Transcription
    • Kanaya, T.; Kyo, S.; Hamada, K.; Takakura, M.; Kitagawa, Y.; Harada, H.; Inoue, M. Adenoviral Expression of p53 Represses Telomerase Activity through Down-Regulation Of Human Telomerase Reverse Transcriptase Transcription. Clin. Cancer Res. 2000,0, 1239-1247.
    • (2000) Clin. Cancer Res. , vol.0 , pp. 1239-1247
    • Kanaya, T.1    Kyo, S.2    Hamada, K.3    Takakura, M.4    Kitagawa, Y.5    Harada, H.6    Inoue, M.7
  • 91
    • 0033559588 scopus 로고    scopus 로고
    • Expression of Human Telomerase Subunits in Ovarian Malignant, Borderline and Benign Tumors
    • Kyo, S.; Kanaya, T.; Takakura, M.; Tanaka, M.; Yamashita, A.; Inoue, H.; Inoue, M. Expression of Human Telomerase Subunits in Ovarian Malignant, Borderline and Benign Tumors. Int. J. Cancer 1999, 80, 804-809.
    • (1999) Int. J. Cancer , vol.80 , pp. 804-809
    • Kyo, S.1    Kanaya, T.2    Takakura, M.3    Tanaka, M.4    Yamashita, A.5    Inoue, H.6    Inoue, M.7
  • 92
    • 0033524343 scopus 로고    scopus 로고
    • Human Telomerase Reverse Transcriptase as a Critical Determinant of Telomerase Activity in Normal and Malignant Endometrial Tissues
    • Kyo, S.; Kanaya, T.; Takakura, M.; Tanaka, M.; Inoue, M. Human Telomerase Reverse Transcriptase as a Critical Determinant of Telomerase Activity in Normal and Malignant Endometrial Tissues. Int. J. Cancer 1999, 80, 60-63.
    • (1999) Int. J. Cancer , vol.80 , pp. 60-63
    • Kyo, S.1    Kanaya, T.2    Takakura, M.3    Tanaka, M.4    Inoue, M.5
  • 93
    • 17144471436 scopus 로고    scopus 로고
    • Proliferation-Associated Regulation of Telomerase Activity in Human Endometrium and its Potential Implication in Early Cancer Diagnosis
    • Saito, T.; Schneider, A.; Martel, N.; Mizumoto, H.; Bulgay-Moerschel, M.; Kudo, R.; Nakazawa, H. Proliferation-Associated Regulation of Telomerase Activity in Human Endometrium and its Potential Implication in Early Cancer Diagnosis. Biochem. Biophys. Res. Commun. 1997,231, 610-614.
    • (1997) Biochem. Biophys. Res. Commun. , vol.231 , pp. 610-614
    • Saito, T.1    Schneider, A.2    Martel, N.3    Mizumoto, H.4    Bulgay-Moerschel, M.5    Kudo, R.6    Nakazawa, H.7
  • 94
    • 0033988011 scopus 로고    scopus 로고
    • Regulation of Telomerase by Alternate Splicing of Human Telomerase Reverse Transcriptase (hTERT) in Normal and Neoplastic Ovary, Endometrium and Myometrium
    • Ulaner, G. A.; Hu, J. F.; Vu, T. H.; Oruganti, H.; Giudice, L.C.; Hoffman, A. R. Regulation of Telomerase by Alternate Splicing of Human Telomerase Reverse Transcriptase (hTERT) in Normal and Neoplastic Ovary, Endometrium and Myometrium. Int. J. Cancer 2000, 85, 330-335.
    • (2000) Int. J. Cancer , vol.85 , pp. 330-335
    • Ulaner, G.A.1    Hu, J.F.2    Vu, T.H.3    Oruganti, H.4    Giudice, L.C.5    Hoffman, A.R.6
  • 95
    • 0031150017 scopus 로고    scopus 로고
    • The Role of Phosphotyrosine Phosphatases in Haematopoietic Cell Signal Transduction
    • Frearson, J. A.; Alexander, D. R. The Role of Phosphotyrosine Phosphatases in Haematopoietic Cell Signal Transduction. Bioessays 1997, 19, 417-427.
    • (1997) Bioessays , vol.19 , pp. 417-427
    • Frearson, J.A.1    Alexander, D.R.2
  • 96
    • 0026547356 scopus 로고
    • Protein Tyrosine Phosphatase Containing SH2 Domains: Characterization, Preferential Expression in Hematopoietic Cells, and Localization to Human Chromosome 12pl2-pl3
    • Yi, T. L.; Cleveland, J. L.; Ihle, J. N. Protein Tyrosine Phosphatase Containing SH2 Domains: Characterization, Preferential Expression in Hematopoietic Cells, and Localization to Human Chromosome 12pl2-pl3. Mol. Cell Biol. 1992, 12, 836-846.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 836-846
    • Yi, T.L.1    Cleveland, J.L.2    Ihle, J.N.3
  • 97
    • 0034703285 scopus 로고    scopus 로고
    • RNA Hyperediting and Alternative Splicing of Hematopoietic Cell Phosphatase (PTPN6) Gene in Acute Myeloid Leukemia
    • Beghini, A.; Ripamonti, C. B.; Peterlongo, P.; Roversi, G.; Cairoli, R.; Morra, E.; Larizza, L. RNA Hyperediting and Alternative Splicing of Hematopoietic Cell Phosphatase (PTPN6) Gene in Acute Myeloid Leukemia. Hum. Mol. Genet. 2000, 9, 2297-2304.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2297-2304
    • Beghini, A.1    Ripamonti, C.B.2    Peterlongo, P.3    Roversi, G.4    Cairoli, R.5    Morra, E.6    Larizza, L.7
  • 98
    • 0008290616 scopus 로고    scopus 로고
    • Diverse Functions of JNK Signaling and c-Jun in Stress Response and Apoptosis
    • Leppa, S.; Bohmann, D. Diverse Functions of JNK Signaling and c-Jun in Stress Response and Apoptosis. Oncogene 1999, 18, 6158-6162.
    • (1999) Oncogene , vol.18 , pp. 6158-6162
    • Leppa, S.1    Bohmann, D.2
  • 99
    • 0032980723 scopus 로고    scopus 로고
    • The Jun Kinase 2 Isoform is Preferentially Required for Epidermal Growth FactorInduced Transformation of Human A549 Lung Carcinoma Cells
    • Best, F.; McKay, R.; Bost, M.; Potapova, O.; Dean, N. M.; Mercola, D. The Jun Kinase 2 Isoform is Preferentially Required for Epidermal Growth FactorInduced Transformation of Human A549 Lung Carcinoma Cells. Mol. Cell Biol. 1999,19, 1938-1949.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 1938-1949
    • Best, F.1    McKay, R.2    Bost, M.3    Potapova, O.4    Dean, N.M.5    Mercola, D.6
  • 100
    • 0030611189 scopus 로고    scopus 로고
    • C-Jun NH2-Terminal Kinase Regulation of the Apoptotic Response of Small Cell Lung Cancer Cells to Ultraviolet Radiation
    • Butterfield, L.; Storey, B.; Maas, L.; Heasley, L. E. c-Jun NH2-Terminal Kinase Regulation of the Apoptotic Response of Small Cell Lung Cancer Cells to Ultraviolet Radiation. J. Biol. Chem. 1997,272, 10110-10116.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10110-10116
    • Butterfield, L.1    Storey, B.2    Maas, L.3    Heasley, L.E.4
  • 102
    • 0030955765 scopus 로고    scopus 로고
    • Regulation of Apoptosis and Cell Cycle Arrest by Zacl, a Novel Zinc Finger Protein Expressed in the Pituitary Gland and the Brain
    • Spengler, D.; Villalba, M.; Hoffmann, A.; Pantaloni, C.; Houssami, S.; Bockaert, J.; Journot, L. Regulation of Apoptosis and Cell Cycle Arrest by Zacl, a Novel Zinc Finger Protein Expressed in the Pituitary Gland and the Brain. EMBO J. 1997,16, 2814-2825.
    • (1997) EMBO J. , vol.16 , pp. 2814-2825
    • Spengler, D.1    Villalba, M.2    Hoffmann, A.3    Pantaloni, C.4    Houssami, S.5    Bockaert, J.6    Journot, L.7
  • 104
    • 0035826177 scopus 로고    scopus 로고
    • Alternative Splicing of the Imprinted Candidate Tumor Suppressor Gene ZAC Regulates its Antiproliferative and DNA Binding Activities
    • Bilanges, B.; Varrault, A.; Mazumdar, A.; Pantaloni, C.; Hoffmann, A.; Bockaert, J.; Spengler, D.; Journot, L. Alternative Splicing of the Imprinted Candidate Tumor Suppressor Gene ZAC Regulates its Antiproliferative and DNA Binding Activities. Oncogene 2001, 20, 1246-1253.
    • (2001) Oncogene , vol.20 , pp. 1246-1253
    • Bilanges, B.1    Varrault, A.2    Mazumdar, A.3    Pantaloni, C.4    Hoffmann, A.5    Bockaert, J.6    Spengler, D.7    Journot, L.8
  • 108
    • 0035912086 scopus 로고    scopus 로고
    • Expression of a Truncated 100 kDa HER2 Splice Variant Acts as an Endogenous Inhibitor of Tumour Cell Proliferation
    • Aigner, A.; Juhl, H.; Malerczyk, C.; Tkybusch, A.; Benz, C. C.; Czubayko, F. Expression of a Truncated 100 kDa HER2 Splice Variant Acts as an Endogenous Inhibitor of Tumour Cell Proliferation. Oncogene 2001, 20, 2101-2111.
    • (2001) Oncogene , vol.20 , pp. 2101-2111
    • Aigner, A.1    Juhl, H.2    Malerczyk, C.3    Tkybusch, A.4    Benz, C.C.5    Czubayko, F.6
  • 109
    • 0034638923 scopus 로고    scopus 로고
    • Mechanisms of Angiogenesis aand their Use in the Inhibition of Tumor Growth and Metastasis
    • Saaristo, A.; Karpanen, T.; Alitalo, K. Mechanisms of Angiogenesis aand their Use in the Inhibition of Tumor Growth and Metastasis. Oncogene 2000, 19, 6122-6129.
    • (2000) Oncogene , vol.19 , pp. 6122-6129
    • Saaristo, A.1    Karpanen, T.2    Alitalo, K.3
  • 111
    • 0031668734 scopus 로고    scopus 로고
    • Tissue-Specific Expression Pattern of Vascular Endothelial Growth Factor Isoforms in the Malignant Transformation of Lung and Colon
    • [Ill] . Cheung, N.; Wong, M. P.; Yuen, S. T.; Leung, S. Y.; Chung, L. P. Tissue-Specific Expression Pattern of Vascular Endothelial Growth Factor Isoforms in the Malignant Transformation of Lung and Colon. Hum. Pathol. 1998, 29, 910-914.
    • (1998) Hum. Pathol. , vol.29 , pp. 910-914
    • Cheung, N.1    Wong, M.P.2    Yuen, S.T.3    Leung, S.Y.4    Chung, L.P.5
  • 112
    • 0035060097 scopus 로고    scopus 로고
    • Specific Reverse Transcription-PCR Quantification of Vascular Endothelial Growth Factor (VEGF) Splice Variants by LightCycler Technology
    • Wellmann, S.; Taube, T.; Paal, K.; Graf, V. E. H.; Geilen, W.; Seifert, G.; Eckert, C.; Henze, G.; Seeger, K. Specific Reverse Transcription-PCR Quantification of Vascular Endothelial Growth Factor (VEGF) Splice Variants by LightCycler Technology. Clin. Chem. 2001, 47, 654-660.
    • (2001) Clin. Chem. , vol.47 , pp. 654-660
    • Wellmann, S.1    Taube, T.2    Paal, K.3    Graf, V.E.H.4    Geilen, W.5    Seifert, G.6    Eckert, C.7    Henze, G.8    Seeger, K.9
  • 114
    • 0033604614 scopus 로고    scopus 로고
    • Signaling via Vascular Endothelial Growth Factor Receptors
    • Petrova, T. V.; Makinen, T.; Alitalo, K. Signaling via Vascular Endothelial Growth Factor Receptors. Exp Cell Res. 1999, 253, 117-130.
    • (1999) Exp Cell Res. , vol.253 , pp. 117-130
    • Petrova, T.V.1    Makinen, T.2    Alitalo, K.3
  • 115
    • 0033730360 scopus 로고    scopus 로고
    • The Short Form of the Alternatively Spliced flt-4 but not its Ligand Vascular Endothelial Growth Factor C is Related to Lymph Node Metastasis in Human Breast Cancers
    • Gunningham, S. P.; Currie, M. J.; Han, C.; Robinson, B. A.; Scott, P. A.; Harris, A. L.; Fox, S. B. The Short Form of the Alternatively Spliced flt-4 but not its Ligand Vascular Endothelial Growth Factor C is Related to Lymph Node Metastasis in Human Breast Cancers. Clin. Cancer Res. 2000, 6, 4278-4286.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 4278-4286
    • Gunningham, S.P.1    Currie, M.J.2    Han, C.3    Robinson, B.A.4    Scott, P.A.5    Harris, A.L.6    Fox, S.B.7
  • 116
    • 0027991841 scopus 로고
    • The Predicted Amino Acid Sequence of Human Thioredoxin is Identical to that of the Autocrine Growth Factor Human Adult T-Cell Derived Factor (ADF): Thioredoxin mRNA is Elevated in Some Human Tumors
    • Gasdaska, P. Y.; Oblong, J. E.; Cotgreave, I. A.; Powis, G. The Predicted Amino Acid Sequence of Human Thioredoxin is Identical to that of the Autocrine Growth Factor Human Adult T-Cell Derived Factor (ADF): Thioredoxin mRNA is Elevated in Some Human Tumors. Biochim. Biophys. Ada 1994,1218, 292-296.
    • (1994) Biochim. Biophys. Ada , vol.1218 , pp. 292-296
    • Gasdaska, P.Y.1    Oblong, J.E.2    Cotgreave, I.A.3    Powis, G.4
  • 117
    • 0030499036 scopus 로고    scopus 로고
    • Thioredoxin and Thioredoxin Reductase Gene Expression in Human Tumors and Cell Lines, and the Effects of Serum Stimulation and Hypoxia
    • Berggren, M.; Gallegos, A.; Gasdaska, J. R.; Gasdaska, P. Y.; Warneke, J.; Powis, G. Thioredoxin and Thioredoxin Reductase Gene Expression in Human Tumors and Cell Lines, and the Effects of Serum Stimulation and Hypoxia Anticancer Res. 1996,16, 3459-3466.
    • (1996) Anticancer Res. , vol.16 , pp. 3459-3466
    • Berggren, M.1    Gallegos, A.2    Gasdaska, J.R.3    Gasdaska, P.Y.4    Warneke, J.5    Powis, G.6
  • 118
    • 0035325959 scopus 로고    scopus 로고
    • Alternative Splicing is Associated with Decreased Expression of the Redox Proto-Oncogene Thioredoxin-1 in Human Cancers
    • Berggren, M. M.; Powis, G. Alternative Splicing is Associated with Decreased Expression of the Redox Proto-Oncogene Thioredoxin-1 in Human Cancers. Arch Biochem. Biophys. 2001, 389, 144-149.
    • (2001) Arch Biochem. Biophys. , vol.389 , pp. 144-149
    • Berggren, M.M.1    Powis, G.2
  • 119
    • 0035844238 scopus 로고    scopus 로고
    • Modification of Alternative Splicing of Bcl-x PremRNA in Prostate and Breast Cancer Cells: Analysis of Apoptosis and Cell Death
    • Mercatante, D. R.; Bortner, C. D.; Cidlowski, J. A.; Kole, R. Modification of Alternative Splicing of Bcl-x PremRNA in Prostate and Breast Cancer Cells: Analysis of Apoptosis and Cell Death. J. Biol. Chem. 2001, 276, 16411-16417.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16411-16417
    • Mercatante, D.R.1    Bortner, C.D.2    Cidlowski, J.A.3    Kole, R.4
  • 120
    • 0003826861 scopus 로고    scopus 로고
    • Induction of Endogenous Bcl-xS through the Control of Bcl-x pre-mRNA Splicing by Antisense Oligonucleotides
    • Taylor, J. K.; Zhang, Q. Q.; Wyatt, J. R.; Dean, N. M. Induction of Endogenous Bcl-xS through the Control of Bcl-x pre-mRNA Splicing by Antisense Oligonucleotides. Nat. Biotechnol. 1999, 17, 1097-1100.
    • (1999) Nat. Biotechnol. , vol.17 , pp. 1097-1100
    • Taylor, J.K.1    Zhang, Q.Q.2    Wyatt, J.R.3    Dean, N.M.4
  • 121
  • 122
    • 0033916111 scopus 로고    scopus 로고
    • Antiproliferative Effects of Steric Blocking Phosphorodiamidate Morpholino Antisense Agents Directed Against C-Myc
    • Hudziak, R. M.; Summerton, J.; Weller, D. D.; Iversen, P. L. Antiproliferative Effects of Steric Blocking Phosphorodiamidate Morpholino Antisense Agents Directed Against C-Myc. Antisense Nucleic Acid Drug Dev.2000,10, 163-176.
    • (2000) Antisense Nucleic Acid Drug Dev. , vol.10 , pp. 163-176
    • Hudziak, R.M.1    Summerton, J.2    Weller, D.D.3    Iversen, P.L.4
  • 123
    • 0026794668 scopus 로고
    • The Mutational Spectrum of Single Base-Pair Substitutions in mRNA Splice Junctions of Human Genes: Causes and Consequences
    • Krawczak, M.; Reiss, J.; Cooper, D. N. The Mutational Spectrum of Single Base-Pair Substitutions in mRNA Splice Junctions of Human Genes: Causes and Consequences. Hum. Genet. 1992, 90, 41-54.
    • (1992) Hum. Genet. , vol.90 , pp. 41-54
    • Krawczak, M.1    Reiss, J.2    Cooper, D.N.3
  • 125
    • 0002541453 scopus 로고
    • Thalassemia Syndromes
    • Huffman, R. et al. ? ed. Churchill Livingston: New York
    • Schwartz, E.; Benz, E. Thalassemia Syndromes. In Hematology: Basic Principles and Practice; Huffman, R. et al. ? ed. Churchill Livingston: New York, 1995, 586-610.
    • (1995) Hematology: Basic Principles and Practice , pp. 586-610
    • Schwartz, E.1    Benz, E.2
  • 127
    • 0033618247 scopus 로고    scopus 로고
    • Antisense oligonucleotides with Different Backbones. Modification of Splicing Pathways and Efficacy of Uptake
    • Schmajuk, G.; Sierakowska, H.; Kole, R. Antisense oligonucleotides with Different Backbones. Modification of Splicing Pathways and Efficacy of Uptake. J. Biol. Chem. 1999,274, 21783-21789.
    • (1999) J. Biol. Chem. , vol.274 , pp. 21783-21789
    • Schmajuk, G.1    Sierakowska, H.2    Kole, R.3
  • 128
    • 0029803547 scopus 로고    scopus 로고
    • Repair of Thalassemic Human Beta-Globin mRNA in Mammalian Cells by Antisense Oligonucleotides
    • Sierakowska, H.; Sambade, M. J.; Agrawal, S.; Kole, R. Repair of Thalassemic Human Beta-Globin mRNA in Mammalian Cells by Antisense Oligonucleotides. Proc. Natl. Acad. Sei. U. S. A. 1996, 93, 12840-12844.
    • (1996) Proc. Natl. Acad. Sei. U. S. A. , vol.93 , pp. 12840-12844
    • Sierakowska, H.1    Sambade, M.J.2    Agrawal, S.3    Kole, R.4
  • 130
    • 0032485884 scopus 로고    scopus 로고
    • Up-Regulation of Luciferase Gene Expression with Antisense Oligonucleotides: Implications and Applications in Functional Assay Development
    • Kang, S. H.; Cho, M. J.; Kole, R. Up-Regulation of Luciferase Gene Expression with Antisense Oligonucleotides: Implications and Applications in Functional Assay Development. Biochemistry 1998, 37, 6235-6239.
    • (1998) Biochemistry , vol.37 , pp. 6235-6239
    • Kang, S.H.1    Cho, M.J.2    Kole, R.3
  • 131
    • 0026699908 scopus 로고
    • Screening for Five Mutations Detects 97% of Cystic Fibrosis (CF) Chromosomes and Predicts a Carrier Frequency of 1:29 in the Jewish Ashkenazi Population
    • Abeliovich, D.; Lavon, I. P.; Lerer, L; Cohen, T.; Springer, C.; Avital, A.; Cutting, G. R. Screening for Five Mutations Detects 97% of Cystic Fibrosis (CF) Chromosomes and Predicts a Carrier Frequency of 1:29 in the Jewish Ashkenazi Population. Am. J. Hum. Genet. 1992,51, 951-956.
    • (1992) Am. J. Hum. Genet. , vol.51 , pp. 951-956
    • Abeliovich, D.1    Lavon, I.P.2    Lerer, L.3    Cohen, T.4    Springer, C.5    Avital, A.6    Cutting, G.R.7
  • 132
    • 0033579478 scopus 로고    scopus 로고
    • Correction of Aberrant Splicing of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) .Gene by Antisense Oligonucleotides
    • Friedman, K. J.; Kole, J.; Cohn, J. A.; Knowles, M. R.; Silverman, L. M.; Kole, R. Correction of Aberrant Splicing of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) .Gene by Antisense Oligonucleotides. J. Biol. Chem. 1999, 274, 36193-36199.
    • (1999) J. Biol. Chem. , vol.274 , pp. 36193-36199
    • Friedman, K.J.1    Kole, J.2    Cohn, J.A.3    Knowles, M.R.4    Silverman, L.M.5    Kole, R.6
  • 133
    • 0026641782 scopus 로고
    • The Spectrum of Cystic Fibrosis Mutations
    • Tsui, L. C. The Spectrum of Cystic Fibrosis Mutations. Trends Genet. 1992, 8, 392-398
    • (1992) Trends Genet. , vol.8 , pp. 392-398
    • Tsui, L.C.1
  • 136
    • 0033044501 scopus 로고    scopus 로고
    • Specific Removal of the Nonsense Mutation from the mdx Dystrophin mRNA Using Antisense Oligonucleotides
    • Wilton, S. D.; Lloyd, F.; Carville, K.; Fletcher, S.; Honeyman, K.; Agrawal, S.; Kole, R. Specific Removal of the Nonsense Mutation from the mdx Dystrophin mRNA Using Antisense Oligonucleotides. Neuromuscul. Disord. 1999, 9, 330-338.
    • (1999) Neuromuscul. Disord. , vol.9 , pp. 330-338
    • Wilton, S.D.1    Lloyd, F.2    Carville, K.3    Fletcher, S.4    Honeyman, K.5    Agrawal, S.6    Kole, R.7
  • 137
    • 0024387161 scopus 로고
    • Cloning and Sequencing of the cDNA Encoding an Isoform of Microtubule-Associated Protein Tau Containing Four Tandem Repeats: Differential Expression of Tau Protein mRNAs in Human Brain
    • Goedert, M.; Spillantini, M. G.; Potier, M. C.; Ulrich, J.; Crowther, R. A. Cloning and Sequencing of the cDNA Encoding an Isoform of Microtubule-Associated Protein Tau Containing Four Tandem Repeats: Differential Expression of Tau Protein mRNAs in Human Brain. EMBO J. 1989, 8. 393-399.
    • (1989) EMBO J. , vol.8 , pp. 393-399
    • Goedert, M.1    Spillantini, M.G.2    Potier, M.C.3    Ulrich, J.4    Crowther, R.A.5
  • 138
    • 0034971707 scopus 로고    scopus 로고
    • Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple. Pathogenic Mechanisms
    • Hutton, M. Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple. Pathogenic Mechanisms. Neurology 2001, 56, S21-S25.
    • (2001) Neurology , vol.56
    • Hutton, M.1
  • 140
    • 0033916608 scopus 로고    scopus 로고
    • Deletion of Individual Exons and Induction of Soluble Murine Interleukin-5 Receptor-Alpha Chain Expression Through Antisense Oligonucleotide-Mediated Redirection of Pre-mRNA Splicing
    • Karras, J. G.; McKay, R. A.; Dean, N. M.; Monia, B. P. Deletion of Individual Exons and Induction of Soluble Murine Interleukin-5 Receptor-Alpha Chain Expression Through Antisense Oligonucleotide-Mediated Redirection of Pre-mRNA Splicing. Mol Pharmacol. 2000, 58, 380-387.
    • (2000) Mol Pharmacol. , vol.58 , pp. 380-387
    • Karras, J.G.1    McKay, R.A.2    Dean, N.M.3    Monia, B.P.4
  • 141
    • 2442740920 scopus 로고
    • History of Antisense Drug Delivery
    • Crooke, S.; LeBleu, B. Eds.; CRC Press, Inc: Boca Raton
    • Zon, G. History of Antisense Drug Delivery In Antisense Research and Applications; Crooke, S.; LeBleu, B. Eds.; CRC Press, Inc: Boca Raton, 1993, 1-3.
    • (1993) Antisense Research and Applications , pp. 1-3
    • Zon, G.1
  • 142
    • 0032750621 scopus 로고    scopus 로고
    • 2′-Carbohydrate Modifications in Antisense Oligonucleotide Therapy: Importance of Conformation, Configuration and Conjugation
    • Manoharan, M. 2′-Carbohydrate Modifications in Antisense Oligonucleotide Therapy: Importance of Conformation, Configuration and Conjugation. Biochim Biophys Acta 1999, 1489, 117-130.
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 117-130
    • Manoharan, M.1
  • 143
    • 0033891369 scopus 로고    scopus 로고
    • Reduction of Liver Fas Expression by an Antisense Oligonucleotide Protects Mice from Fulminant Hepatitis
    • Zhang, H.; Cook, J.; Nickel, J.; Yu, R.; Stecker, K.; Myers, K.; Dean, N. M. Reduction of Liver Fas Expression by an Antisense Oligonucleotide Protects Mice from Fulminant Hepatitis. Nat. Biotechnol. 2000, 18, 862-867.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 862-867
    • Zhang, H.1    Cook, J.2    Nickel, J.3    Yu, R.4    Stecker, K.5    Myers, K.6    Dean, N.M.7
  • 146
    • 0034938693 scopus 로고    scopus 로고
    • Locked Nucleic Acids: A Promising Molecular Family for Gene-Function Analysis and Antisense Drug Development
    • Orum, H.; Wengel, J. Locked Nucleic Acids: A Promising Molecular Family for Gene-Function Analysis and Antisense Drug Development Curr. Opin. Mol. Ther. 2001, 3, 239-243.
    • (2001) Curr. Opin. Mol. Ther. , vol.3 , pp. 239-243
    • Orum, H.1    Wengel, J.2
  • 147
    • 0034744290 scopus 로고    scopus 로고
    • 2′-O,4′-C-Methylene Bridged Nucleic Acid (2′,4′-BNA):. Synthesis and Triplex-Forming Properties
    • Obika, S.; Uneda, T.; Sugimoto, T.; Nanbu, D.; Minami, T.; Doi, T.; Imanishi, T. 2′-O,4′-C-Methylene Bridged Nucleic Acid (2′,4′-BNA):. Synthesis and Triplex-Forming Properties. Bioorg. Med. Chem. 2001, 9, 1001-1011.
    • (2001) Bioorg. Med. Chem. , vol.9 , pp. 1001-1011
    • Obika, S.1    Uneda, T.2    Sugimoto, T.3    Nanbu, D.4    Minami, T.5    Doi, T.6    Imanishi, T.7
  • 148
    • 0035951767 scopus 로고    scopus 로고
    • 2′-O,4′-C-Methylene Bridged Nucleic Acid Modification Promotes Pyrimidine Motif Triplex DNA Formation at Physiological pH
    • Torigoe, H.; Hari, Y.; Sekiguchi, M.; Obika, S.; Imanishi, T. 2′-O,4′-C-Methylene Bridged Nucleic Acid Modification Promotes Pyrimidine Motif Triplex DNA Formation at Physiological pH. J. Biol. Chem. 2001, 270, 2354-2360.
    • (2001) J. Biol. Chem. , vol.270 , pp. 2354-2360
    • Torigoe, H.1    Hari, Y.2    Sekiguchi, M.3    Obika, S.4    Imanishi, T.5
  • 149
    • 0032699477 scopus 로고    scopus 로고
    • Morpholino Antisense Oligomers: The Case for an RNase H-Independent Structural Type
    • Summerton, J. Morpholino Antisense Oligomers: the Case for an RNase H-Independent Structural Type. Biochim. Biophys. Acta 1999, 1489, 141-158.
    • (1999) Biochim. Biophys. Acta , vol.1489 , pp. 141-158
    • Summerton, J.1
  • 150
    • 0033780376 scopus 로고    scopus 로고
    • Effective Targeted Tene 'Knockdown' in Zebrafish
    • Nasevicius, A.; Ekker, S. C. Effective Targeted Tene 'Knockdown' in Zebrafish. Nat. Genet. 2000, 26, 216-220.
    • (2000) Nat. Genet. , vol.26 , pp. 216-220
    • Nasevicius, A.1    Ekker, S.C.2
  • 151
    • 0031828692 scopus 로고    scopus 로고
    • Effect of TNF-Alpha Antisense Oligomers on Cytokine Production by Primary Murine Alveolar Macrophages
    • Taylor, M. F.; Weller, D. D.; Kobzik, L. Effect of TNF-Alpha Antisense Oligomers on Cytokine Production by Primary Murine Alveolar Macrophages. Antisense Nucleic Acid Drug Dev. 1998, 8. 199-205.
    • (1998) Antisense Nucleic Acid Drug Dev. , vol.8 , pp. 199-205
    • Taylor, M.F.1    Weller, D.D.2    Kobzik, L.3
  • 152
    • 0029337139 scopus 로고
    • Synthesis of Novel Phosphoramidite Reagents for the Attachment of Antisense Oligonucleotides to Various Regions of the Benzophenanthridine Ring System
    • Chen, J. K.; Weith, H. L.; Grevval, R. S.; Wang, G.; Cushman, M. Synthesis of Novel Phosphoramidite Reagents for the Attachment of Antisense Oligonucleotides to Various Regions of the Benzophenanthridine Ring System. Bioconjug. Chem. 1995,5, 473-482.
    • (1995) Bioconjug. Chem. , vol.5 , pp. 473-482
    • Chen, J.K.1    Weith, H.L.2    Grevval, R.S.3    Wang, G.4    Cushman, M.5
  • 156
    • 0032708143 scopus 로고    scopus 로고
    • Inhibition of IL-6 in Mice by Anti-NF-KappaB Oligodeoxyribonucleotide N3′->oligodeoxyribon-nucleotide N3′-> P5′ Phosphoramidates
    • Wang, L.; Gryaznov, S.; Nerenberg, M. Inhibition of IL-6 in Mice by Anti-NF-KappaB Oligodeoxyribonucleotide N3′->oligodeoxyribon-nucleotide N3′-> P5′ Phosphoramidates Inflammation 1999, 23, 583-590.
    • (1999) Inflammation , vol.23 , pp. 583-590
    • Wang, L.1    Gryaznov, S.2    Nerenberg, M.3
  • 159
    • 0030960680 scopus 로고    scopus 로고
    • Pharmacokinetic Considerations in the Development of Oligomers as Radiopharmaceuticals
    • Hnatowich, D. J. Pharmacokinetic Considerations in the Development of Oligomers as Radiopharmaceuticals. Q. J. Nucl. Med. 1997, 41, 91-100.
    • (1997) Q. J. Nucl. Med. , vol.41 , pp. 91-100
    • Hnatowich, D.J.1
  • 160
    • 0028921636 scopus 로고
    • Modified Oligonucleotides as Therapeutic and Diagnostic Agents
    • Agrawal, S.; lyer, R. P. Modified Oligonucleotides as Therapeutic and Diagnostic Agents. Curr. Opin. Biotechnol. 1995, 6, 12-19.
    • (1995) Curr. Opin. Biotechnol. , vol.6 , pp. 12-19
    • Agrawal, S.1    Lyer, R.P.2
  • 161
    • 0034018927 scopus 로고    scopus 로고
    • Studies on Anti-human Immunodeficiency Virus Oligonucleotides that have Alternating Methylphosphonate/Phosphodiester Linkages
    • Miller, P. S.; Cassidy, R. A.; Hamma, T.; Kondo, N.S. Studies on Anti-human Immunodeficiency Virus Oligonucleotides that have Alternating Methylphosphonate/Phosphodiester Linkages. Pharmacol. Ther. 2000, 85, 159-163.
    • (2000) Pharmacol. Ther. , vol.85 , pp. 159-163
    • Miller, P.S.1    Cassidy, R.A.2    Hamma, T.3    Kondo, N.S.4
  • 162
    • 0033812002 scopus 로고    scopus 로고
    • Heterocyclic Modifications of Oligonucleotides and Antisense Technology
    • Herdewijn, P. Heterocyclic Modifications of Oligonucleotides and Antisense Technology. Antisense Nucleic Acid Drug Dev. 2000,10, 297-310.
    • (2000) Antisense Nucleic Acid Drug Dev. , vol.10 , pp. 297-310
    • Herdewijn, P.1
  • 163
    • 0030057861 scopus 로고    scopus 로고
    • Effects of Oligonucleotide Length, Mismatches and mRNA Levels on C-5 Propyne-modified Antisense Potency
    • Flanagan, W. M.; Kothavale, A.; Wagner, R. W. Effects of Oligonucleotide Length, Mismatches and mRNA Levels on C-5 Propyne-modified Antisense Potency. Nucleic Acids Res. 1996, 24, 2936-2941.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2936-2941
    • Flanagan, W.M.1    Kothavale, A.2    Wagner, R.W.3
  • 165
    • 0032528042 scopus 로고    scopus 로고
    • Biophysical and Antisense Properties of Oligodeoxynucleotides Containing 7-Propynyl-, 7-iodo- And 7-cyano-7-deaza-2-amino-2′-deoxyadenosines
    • Balow, G.; Mohan, V.; Lesnik, E. A.; Johnston, J. F.; Monia, B. P.; Acevedo, O. L. Biophysical and Antisense Properties of Oligodeoxynucleotides Containing 7-Propynyl-, 7-iodo- and 7-cyano-7-deaza-2-amino-2′-deoxyadenosines. Nucleic Acids Res. 1998, 26, 3350-3357.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 3350-3357
    • Balow, G.1    Mohan, V.2    Lesnik, E.A.3    Johnston, J.F.4    Monia, B.P.5    Acevedo, O.L.6
  • 168
    • 0033403876 scopus 로고    scopus 로고
    • Delivery of Antisense Oligonucleotides and Plasmid DNA with Various Carrier Agents
    • Kang, S. H.; Zirbes, E. L.; Kole, R. Delivery of Antisense Oligonucleotides and Plasmid DNA with Various Carrier Agents. Antisense Nucleic Acid Drug Dev. 1999, 9, 497-505.
    • (1999) Antisense Nucleic Acid Drug Dev. , vol.9 , pp. 497-505
    • Kang, S.H.1    Zirbes, E.L.2    Kole, R.3
  • 169
    • 0034326297 scopus 로고    scopus 로고
    • Enhanced Delivery of Antisense Oligonucleotides with Fluorophore-Conjugated PAMAM Dendrimers
    • Yoo, H.; Juliano, R. L. Enhanced Delivery of Antisense Oligonucleotides with Fluorophore-Conjugated PAMAM Dendrimers. Nucleic Acids Res. 2000, 28, 4225-4231.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 4225-4231
    • Yoo, H.1    Juliano, R.L.2
  • 170
    • 0342748741 scopus 로고    scopus 로고
    • Lipid Carrier with a Membrane Active Component and a Small Complex Size are Required for Efficient Cellular Delivery of Anti-sense Phosphorothioate Oligonucleotides
    • Jaaskelainen, I.; Peltola, S.; Honkakoski, P.; Monkkonen, J.; Urtti, A. A Lipid Carrier with a Membrane Active Component and a Small Complex Size are Required for Efficient Cellular Delivery of Anti-sense Phosphorothioate Oligonucleotides. Eur. J. Pharm. Sei. .2000,70, 187-193.
    • (2000) Eur. J. Pharm. Sei. . , vol.70 , pp. 187-193
    • Jaaskelainen, I.1    Peltola, S.2    Honkakoski, P.3    Monkkonen, J.4    Urtti, A.A.5
  • 171
    • 0034656564 scopus 로고    scopus 로고
    • Antisense Delivery Using Protamine-Oligonucleotide Particles
    • Junghans, M.; Kreuter, J.; Zimmer, A. Antisense Delivery Using Protamine-Oligonucleotide Particles. Nucleic Acids Res. 2000, 28, E45.
    • (2000) Nucleic Acids Res. , vol.28
    • Junghans, M.1    Kreuter, J.2    Zimmer, A.3
  • 172
    • 0035937597 scopus 로고    scopus 로고
    • Nanoparticulate Systems for the Delivery of Antisense Oligonucleotides
    • Lambert, G.; Fattal, E.; Couvreur, P. Nanoparticulate Systems for the Delivery of Antisense Oligonucleotides. Adv. Drug Deliv. Rev. 2001, 47, 99-112.
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , pp. 99-112
    • Lambert, G.1    Fattal, E.2    Couvreur, P.3
  • 173
    • 0035910877 scopus 로고    scopus 로고
    • Comparison of Two Methods of Encapsulation of an Oligonucleotide into Poly(D,L-lactic acid) Particles
    • Delie, F.; Berton, M.; Allemann, E.; Gurny, R. Comparison of Two Methods of Encapsulation of an Oligonucleotide into Poly(D,L-lactic acid) Particles. Int. J. Pharm. 2001, 214, 25-30.
    • (2001) Int. J. Pharm. , vol.214 , pp. 25-30
    • Delie, F.1    Berton, M.2    Allemann, E.3    Gurny, R.4
  • 175
    • 0035868266 scopus 로고    scopus 로고
    • Delivery of Oligonucleotides into Mammalian Cells by Anionic Peptides: Comparison between Monomeric and Dimeric Peptides
    • Freuion, L; Roche, A. C.; Monsigny, M.; Mayer, R. Delivery of Oligonucleotides into Mammalian Cells by Anionic Peptides: Comparison between Monomeric and Dimeric Peptides. Biochem. J.2001,354, 671-679.
    • (2001) Biochem. J. , vol.354 , pp. 671-679
    • Freuion, L.1    Roche, A.C.2    Monsigny, M.3    Mayer, R.4
  • 177
    • 0031984072 scopus 로고    scopus 로고
    • Trojan Peptides: The Penetrating System for Intracellular Delivery
    • Derossi, D.; Chassaing, G.; Prochiantz, A. Trojan Peptides: The Penetrating System for Intracellular Delivery. Trends Cell Biol. 1998, 8, 84-87.
    • (1998) Trends Cell Biol. , vol.8 , pp. 84-87
    • Derossi, D.1    Chassaing, G.2    Prochiantz, A.3
  • 178
    • 0034012647 scopus 로고    scopus 로고
    • Antisense.inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates
    • Astriab-Fisher, A.; Sergueev, D. S.; Fisher, M.; Shaw, B. R.; Juliano, R. L. Antisense.inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates. Biochem. Pharmacol. 2000, 60, 83-90.
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 83-90
    • Astriab-Fisher, A.1    Sergueev, D.S.2    Fisher, M.3    Shaw, B.R.4    Juliano, R.L.5
  • 179
    • 0034945672 scopus 로고    scopus 로고
    • Antisense Effects in the Cell Nucleus: Modification of Splicing
    • Kole, R.; Sazani, P. Antisense Effects in the Cell Nucleus: Modification of Splicing. Curr. Opin. Molec. Therapeut. 2001, 3, 229-234.
    • (2001) Curr. Opin. Molec. Therapeut. , vol.3 , pp. 229-234
    • Kole, R.1    Sazani, P.2
  • 180
    • 0035937124 scopus 로고    scopus 로고
    • Arginine-Rich Peptides. An Abundant Source of Membrane-Permeable Peptides having Potential as Carriers for Intracellular Protein Delivery
    • Futaki, S.; Suzuki, T.; Ohashi, W.; Yagami, T.; Tanaka, S.; Ueda, K.; Sugiura, Y. Arginine-Rich Peptides. An Abundant Source of Membrane-Permeable Peptides having Potential as Carriers for Intracellular Protein Delivery. J. Biol. Chem. 2001, 270, 5836-5840.
    • (2001) J. Biol. Chem. , vol.270 , pp. 5836-5840
    • Futaki, S.1    Suzuki, T.2    Ohashi, W.3    Yagami, T.4    Tanaka, S.5    Ueda, K.6    Sugiura, Y.7
  • 183
    • 0035900725 scopus 로고    scopus 로고
    • Correction of alternative splicing of tau in frontotemporal dementia and parkinsonsim linked to chromosome 17
    • in press
    • Kalbfuss, B.; Mabon, S.A.; Misteli, T. Correction of alternative splicing of tau in frontotemporal dementia and parkinsonsim linked to chromosome 17. J. Biol. Chem. in press.
    • J. Biol. Chem.
    • Kalbfuss, B.1    Mabon, S.A.2    Misteli, T.3


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