-
1
-
-
2042437650
-
Initial Sequencing and Analysis of the Human Genome
-
Lander, E. S.; Linton, L. M.; Birren, B.; Nusbaum, C. Zody, M. C.; Baldwin, J.; Devon, K.; Dewar, K.; Doyle M.; FitzHugh, W.; Funke, R.; Gage, D.; Harris, K. Heaford, A.; Rowland, J.; Kann, L.; Lehoczky, J. LeVine, R.; McEwan, P.; McKernan, K.; Meldrim, J. Mesirov, J.P.; Miranda, C.; Morris, W.; Naylor, J., et al. Initial Sequencing and Analysis of the Human Genome Nature 2001, 409, 860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Zody M C, N.C.4
Baldwin, J.5
Devon, K.6
Dewar, K.7
Doyle, M.8
Fitzhugh, W.9
Funke, R.10
Gage, D.11
Heaford A, H.K.12
Rowland, J.13
Kann, L.14
Levine R, L.J.15
McEwan, P.16
McKernan, K.17
Meldrim, J.18
Mesirov, J.P.19
Miranda, C.20
Morris, W.21
Naylor, J.22
more..
-
2
-
-
0035895505
-
The Sequence of the Human Genome
-
Venter, J. C.; Adams, M. D.; Myers, E. W.; Li, P. W. Mural, R. J.; Sutton, G. G.; Smith, H. O.; Yandell, M. Evans, C. A.; Holt, R. A.; Gocayne, J. D.; Amanatides, P. Ballew, R. M.; Huson, D. H.; Wortman, J. R.; Zhang, Q. Kodira, C. D.; Zheng, X. H.; Chen, L.; Skupski, M. Subramanian, G.; Thomas, P. D.; Zhang, J.; Gabor-Miklos, G. L.; Nelson, C., et al. The Sequence of the Human Genome. Science 2001, 297, 1304-1351.
-
(2001)
Science
, vol.297
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Mural R J, L.P.W.4
Sutton, G.G.5
Smith, H.O.6
Evans C A, Y.M.7
Holt, R.A.8
Gocayne, J.D.9
Ballew R M, A.P.10
Huson, D.H.11
Wortman, J.R.12
Kodira C D, Z.Q.13
Zheng, X.H.14
Chen, L.15
Subramanian G, S.M.16
Thomas, P.D.17
Zhang, J.18
Gabor-Miklos, G.L.19
Nelson, C.20
more..
-
3
-
-
0035252410
-
Alternative Splicing: Increasing Diversity in the Proteomic World
-
Graveley, B. R. Alternative Splicing: Increasing Diversity in the Proteomic World. Trends Genet. 2001, 17, 100-107.
-
(2001)
Trends Genet.
, vol.17
, pp. 100-107
-
-
Graveley, B.R.1
-
4
-
-
0034256020
-
Alternative Pre-mRNA Splicing: The Logic of Combinatorial Control
-
Smith, C. W.; Valcarcel, J. Alternative Pre-mRNA Splicing: The Logic of Combinatorial Control. Trends Biochem. Sei. 2000, 25, 381-388.
-
(2000)
Trends Biochem. Sei.
, vol.25
, pp. 381-388
-
-
Smith, C.W.1
Valcarcel, J.2
-
5
-
-
33747011774
-
Eukaryptic mRNA Processing
-
Harnes, B. D.; Glover, D. M., Eds.; Oxford University Press: New York
-
Krainer, A. R. Eukaryptic mRNA Processing. In Frontiers in Molecular Biology; Harnes, B. D.; Glover, D. M., Eds.; Oxford University Press: New York, 1997.
-
(1997)
Frontiers in Molecular Biology
-
-
Krainer, A.R.1
-
6
-
-
0033578006
-
Stage-Specific Changes in Sr Splicing Factors and Alternative Splicing in Mammary Tumorigenesis
-
Stickeier, E.; Kittrell, F.; Medina, D.; Berget, S. M. Stage-Specific Changes in Sr Splicing Factors and Alternative Splicing in Mammary Tumorigenesis. Oncogene 1999, 18, 3574-3582.
-
(1999)
Oncogene
, vol.18
, pp. 3574-3582
-
-
Stickeier, E.1
Kittrell, F.2
Medina, D.3
Berget, S.M.4
-
7
-
-
0034163539
-
Fibroblast Growth Factor Receptor-1 Alpha-Exon Exclusion and Polypyrimidine Tract-Binding Protein in Glioblastoma Multiforme Tumors
-
Jin, W.; McCutcheon, I. E.; Fuller, G. N.; Huang, E. S.; Cote, G. J. Fibroblast Growth Factor Receptor-1 Alpha-Exon Exclusion and Polypyrimidine Tract-Binding Protein in Glioblastoma Multiforme Tumors. Cancer Res. 2000,60, 1221-1224.
-
(2000)
Cancer Res.
, vol.60
, pp. 1221-1224
-
-
Jin, W.1
McCutcheon, I.E.2
Fuller, G.N.3
Huang, E.S.4
Cote, G.J.5
-
8
-
-
0032739144
-
The Interaction and Colocalization of Sam68 with the Splicing-Associated Factor YT521-B in Nuclear Dots is Regulated by the Src Family Kinase p59(fyn)
-
Hartmann, A. M.; Nayler, O.; Schwaiger, F. W.; Obermeier, A.; Stamm, S. The Interaction and Colocalization of Sam68 with the Splicing-Associated Factor YT521-B in Nuclear Dots is Regulated by the Src Family Kinase p59(fyn). Mol. Biol. Cell 1999, 10, 3909-3926.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3909-3926
-
-
Hartmann, A.M.1
Nayler, O.2
Schwaiger, F.W.3
Obermeier, A.4
Stamm, S.5
-
9
-
-
0035912224
-
A CaMK. IV Responsive RNA Element Mediates Depolarization-Induced Alternative Splicing of Ion Channels
-
Xie, J.; Black, D. L. A CaMK. IV Responsive RNA Element Mediates Depolarization-Induced Alternative Splicing of Ion Channels. Nature 2001, 410, 936-939.
-
(2001)
Nature
, vol.410
, pp. 936-939
-
-
Xie, J.1
Black, D.L.2
-
10
-
-
0033576674
-
Stress-Induced Aberrant Splicing of TSG101: Association to High Tumor Grade and p53 Status in Breast Cancers
-
Turpin, E.; Dalle, B.; de Roquancourt, A.; Plassa, L. F.; Marty, M.; Janin, A.; Beuzard, Y.; de The, H. Stress-Induced Aberrant Splicing of TSG101: Association to High Tumor Grade and p53 Status in Breast Cancers. Oncogene 1999, 18, 7834-7837.
-
(1999)
Oncogene
, vol.18
, pp. 7834-7837
-
-
Turpin, E.1
Dalle, B.2
De Roquancourt, A.3
Plassa, L.F.4
Marty, M.5
Janin, A.6
Beuzard, Y.7
De The, H.8
-
11
-
-
0030854026
-
Aberrant Splicing but not Mutations of TSG101 in Human Breast Cancer
-
Lee, M. P.; Feinberg, A. P. Aberrant Splicing but not Mutations of TSG101 in Human Breast Cancer. Cancer Res. 1997, 57, 3131-3134.
-
(1997)
Cancer Res.
, vol.57
, pp. 3131-3134
-
-
Lee, M.P.1
Feinberg, A.P.2
-
12
-
-
0031600117
-
The Heparan Sulfate-Fibroblast Growth Factor Family: Diversity of Structure and Function
-
McKeehan, W. L.; Wang, F.; Kan, M. The Heparan Sulfate-Fibroblast Growth Factor Family: Diversity of Structure and Function. Prog. Nucleic Acid Res. Mol. Biol. 1998, 59, 135-376.
-
(1998)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.59
, pp. 135-376
-
-
McKeehan, W.L.1
Wang, F.2
Kan, M.3
-
13
-
-
0031317928
-
Fibroblast Growth Factors and their Receptors
-
Galzie, Z.; Kinsella, A. R.; Smith, J.A. Fibroblast Growth Factors and their Receptors. Biochem. Cell. Biol. 1997, 75, 669-685.
-
(1997)
Biochem. Cell. Biol.
, vol.75
, pp. 669-685
-
-
Galzie, Z.1
Kinsella, A.R.2
Smith, J.A.3
-
14
-
-
0027344852
-
Structural and Functional Diversity in the FGF Receptor Multigene Family
-
Johnson, D. E.; Williams, L. T. Structural and Functional Diversity in the FGF Receptor Multigene Family. Adv. Cancer Res. 1993, 60, 1-41.
-
(1993)
Adv. Cancer Res.
, vol.60
, pp. 1-41
-
-
Johnson, D.E.1
Williams, L.T.2
-
15
-
-
0031577732
-
Alternative Splicing of Fibroblast Growth Factor Receptor 2 (FGF-R2) in Human Prostate Cancer
-
Carstens, R. P.; Eaton, J. V.; Krigman, H. R.; Walther, P. J.; Garcia-Blanco, M. A. Alternative Splicing of Fibroblast Growth Factor Receptor 2 (FGF-R2) in Human Prostate Cancer. Oncogene 1997,15, 3059-3065.
-
(1997)
Oncogene
, vol.15
, pp. 3059-3065
-
-
Carstens, R.P.1
Eaton, J.V.2
Krigman, H.R.3
Walther, P.J.4
Garcia-Blanco, M.A.5
-
16
-
-
0035253320
-
Alternative Splicing of Fibroblast Growth Factor Receptors in Human Prostate Cancer
-
Kwabi-Addo, B.; Ropiquet, F.; Giri, D.; Ittmann, M. Alternative Splicing of Fibroblast Growth Factor Receptors in Human Prostate Cancer. Prostate 2001, 46, 163-172.
-
(2001)
Prostate
, vol.46
, pp. 163-172
-
-
Kwabi-Addo, B.1
Ropiquet, F.2
Giri, D.3
Ittmann, M.4
-
17
-
-
0033835133
-
An Intronic Splicing Silencer Causes Skipping of the Illb Exon of Fibroblast Growth Factor Receptor 2 through Involvement of Polypyrimidine Tract Binding Protein
-
Carstens, R. P.; Wagner, E.J.; Garcia-Blanco, M.A. An Intronic Splicing Silencer Causes Skipping of the Illb Exon of Fibroblast Growth Factor Receptor 2 through Involvement of Polypyrimidine Tract Binding Protein. Mol. Cell Biol. 2000, 20, 7388-7400.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 7388-7400
-
-
Carstens, R.P.1
Wagner, E.J.2
Garcia-Blanco, M.A.3
-
18
-
-
0029917507
-
Fibroblast Growth Factor Receptor 3 is a Negative Regulator of Bone Growth
-
Deng, C.; Wynshaw-Boris, A.; Zhou, F.; Kuo, A.; Leder, P. Fibroblast Growth Factor Receptor 3 is a Negative Regulator of Bone Growth. Cell 1996, 84, 911-921.
-
(1996)
Cell
, vol.84
, pp. 911-921
-
-
Deng, C.1
Wynshaw-Boris, A.2
Zhou, F.3
Kuo, A.4
Leder, P.5
-
19
-
-
0033900046
-
Novel Transcripts of Fibroblast Growth Factor Receptor 3 Reveal Aberrant Splicing and Activation of Cryptic Splice Sequences in Colorectal Cancer
-
Jang, J. H.; Shin, K. H.; Park, Y. J.; Lee, R. J.; McKeehan, W. L.; Park, J. G. Novel Transcripts of Fibroblast Growth Factor Receptor 3 Reveal Aberrant Splicing and Activation of Cryptic Splice Sequences in Colorectal Cancer. Cancer Res. 2000, 60, 4049-4052.
-
(2000)
Cancer Res.
, vol.60
, pp. 4049-4052
-
-
Jang, J.H.1
Shin, K.H.2
Park, Y.J.3
Lee, R.J.4
McKeehan, W.L.5
Park, J.G.6
-
20
-
-
0034685038
-
Identification of a Novel Alternative Splicing of Human FGF Receptor 4: SolubleForm Splice Variant Expressed in Human Gastrointestinal Epithelial Cells
-
Takaishi, S.; Sawada, M.; Morita, Y.; Seno, H.; Fukuzawa, H.; Chiba, T. Identification of a Novel Alternative Splicing of Human FGF Receptor 4: SolubleForm Splice Variant Expressed in Human Gastrointestinal Epithelial Cells. Biochem. Biophys. Res. Commun. 2000, 267, 658-662.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.267
, pp. 658-662
-
-
Takaishi, S.1
Sawada, M.2
Morita, Y.3
Seno, H.4
Fukuzawa, H.5
Chiba, T.6
-
21
-
-
0035835816
-
Wilms Tumor and the WT1 Gene
-
Lee, S. B.; Haber, D. A. Wilms Tumor and the WT1 Gene. Exp. Cell Res. 2001, 264, 74-99.
-
(2001)
Exp. Cell Res.
, vol.264
, pp. 74-99
-
-
Lee, S.B.1
Haber, D.A.2
-
22
-
-
0030805513
-
Differential Splicing of Exon 5 of the Wilms Tumour (WTI) Gene
-
Renshaw, J.; King-Underwood, L.; Pritchard-Jones, K. Differential Splicing of Exon 5 of the Wilms Tumour (WTI) Gene. Genes Chromosomes Cancer 1997, 19, 256-266.
-
(1997)
Genes Chromosomes Cancer
, vol.19
, pp. 256-266
-
-
Renshaw, J.1
King-Underwood, L.2
Pritchard-Jones, K.3
-
24
-
-
0033561499
-
Analysis of Native WTI Protein from Frozen Human Kidney and Wilms1 Tumors
-
Iben, S.; Royer-Pokora, B. Analysis of Native WTI Protein from Frozen Human Kidney and Wilms1 Tumors. Oncogene 1999, 18, 2533-2536.
-
(1999)
Oncogene
, vol.18
, pp. 2533-2536
-
-
Iben, S.1
Royer-Pokora, B.2
-
25
-
-
0035252110
-
Par4 is a Coactivator for a Splice IsoformSpecific Transcriptional Activation Domain in WTI
-
Richard, D.J.; Schumacher, V.; Royer-Pokora, B.; Roberts, S. G. Par4 is a Coactivator for a Splice IsoformSpecific Transcriptional Activation Domain in WTI. Genes Dey. 2001, 15, 328-339.
-
(2001)
Genes Dey.
, vol.15
, pp. 328-339
-
-
Richard, D.J.1
Schumacher, V.2
Royer-Pokora, B.3
Roberts, S.G.4
-
26
-
-
0032548827
-
BRCA1, BRCA2, and DNA Damage Response: Collision or Collusion?
-
Zhang, H.; Tombline, G.; Weber, B.L. BRCA1, BRCA2, and DNA Damage Response: Collision or Collusion? Cell 1998, 92, 433-436.
-
(1998)
Cell
, vol.92
, pp. 433-436
-
-
Zhang, H.1
Tombline, G.2
Weber, B.L.3
-
27
-
-
0029795422
-
Characterization of Functional Messenger RNA Splice Variants of BRCA1 Expressed in Nonmalignant and Tumor-Derived Breast Cells
-
Lu, M.; Conzen, S. D.; Cole, C. N.; Arrick, B. A. Characterization of Functional Messenger RNA Splice Variants of BRCA1 Expressed in Nonmalignant and Tumor-Derived Breast Cells. Cancer Res. 1996, 56, 4578-4581.
-
(1996)
Cancer Res.
, vol.56
, pp. 4578-4581
-
-
Lu, M.1
Conzen, S.D.2
Cole, C.N.3
Arrick, B.A.4
-
28
-
-
0028113345
-
A.Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1
-
Miki, Y.; Swensen, J.; Shattuck-Eidens, D.; Futreal, P. A.; Harshman, K.; Tavtigian, S.; Liu, Q.; Cochran, C.; Bennett, L. M.; Ding, W.; et al. A.Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1. Science. 1994, 266, 66-71.
-
(1994)
Science.
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
Futreal, P.A.4
Harshman, K.5
Tavtigian, S.6
Liu, Q.7
Cochran, C.8
Bennett, L.M.9
Ding, W.10
-
29
-
-
1842364973
-
Localization of BRCA1 and a Splice Variant Identifies the Nuclear Localization Signal
-
Thakur, S.; Zhang, H. B.; Peng, Y.; Le, H.; Carroll, B.; Ward, T.; Yao, J.; Farid, L. M.; Couch, F. J.; Wilson, R. B.; Weber, B. L. Localization of BRCA1 and a Splice Variant Identifies the Nuclear Localization Signal. Mol. Cell Biol. 1997, 17, 444-452.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 444-452
-
-
Thakur, S.1
Zhang, H.B.2
Peng, Y.3
Le, H.4
Carroll, B.5
Ward, T.6
Yao, J.7
Farid, L.M.8
Couch, F.J.9
Wilson, R.B.10
Weber, B.L.11
-
30
-
-
0034816781
-
Expression Profiles of BRCA1 Splice Variants in Asynchronous and in Gl/S Synchronized Tumor Cell Lines
-
Orban, T. I.; Olah, E. Expression Profiles of BRCA1 Splice Variants in Asynchronous and in Gl/S Synchronized Tumor Cell Lines. Biochem. Biophys. Res. Commun. 2001, 250, 32-38.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.250
, pp. 32-38
-
-
Orban, T.I.1
Olah, E.2
-
31
-
-
0033152121
-
Increased Level of Exon 12 Alternatively Spliced BRCA2 Transcripts in Tumor Breast Tissue Compared with Normal Tissue
-
Bieche, I.; Lidereau, R. Increased Level of Exon 12 Alternatively Spliced BRCA2 Transcripts in Tumor Breast Tissue Compared with Normal Tissue. Cancer Res. 1999, 59, 2546-2550.
-
(1999)
Cancer Res.
, vol.59
, pp. 2546-2550
-
-
Bieche, I.1
Lidereau, R.2
-
32
-
-
0001873478
-
Molecular Studies into the Role of CD44 Variants in Metastasis in Gastric Cancer
-
Hsieh, H. F.; Yu, J. C.; Ho, L. I.; Chiu, S. C.; Harn, H. J. Molecular Studies into the Role of CD44 Variants in Metastasis in Gastric Cancer. Mol. Pathol. 1999, 52, 2528.
-
(1999)
Mol. Pathol.
, vol.52
, pp. 2528
-
-
Hsieh, H.F.1
Yu, J.C.2
Ho, L.I.3
Chiu, S.C.4
Harn, H.J.5
-
33
-
-
0031874645
-
The Normal Structure and Function of CD44 and its Role in Neoplasia
-
Sneath, R. J.; Mangham, D. C. The Normal Structure And Function Of CD44 and its Role in Neoplasia. Mol. Pathol. 1998, 51, 191-200.
-
(1998)
Mol. Pathol.
, vol.51
, pp. 191-200
-
-
Sneath, R.J.1
Mangham, D.C.2
-
34
-
-
0034013966
-
The CD44 Receptor of the Mouse LB T-Cell Lymphoma: Analysis of the Isoform Repertoire and Ligand Binding Properties by Reverse-Transcriptase Polymerase Chain Reaction and Antisense Oligonucleotides
-
Wallach, S. B.; Friedmann, A.; Naor, D. The CD44 Receptor of the Mouse LB T-Cell Lymphoma: Analysis of the Isoform Repertoire and Ligand Binding Properties by Reverse-Transcriptase Polymerase Chain Reaction and Antisense Oligonucleotides. Cancer Detect. Prev. 2000. 24, 33-45.
-
(2000)
Cancer Detect. Prev.
, vol.24
, pp. 33-45
-
-
Wallach, S.B.1
Friedmann, A.2
Naor, D.3
-
35
-
-
0032791736
-
Adhesion Proteins in the Biology of Breast Cancer: Contribution of CD44
-
Herrera-Gayol, A.; Jothy, S. Adhesion Proteins in the Biology of Breast Cancer: Contribution of CD44. Exp. Mol. Pathol. 1999, 66, 149-156.
-
(1999)
Exp. Mol. Pathol.
, vol.66
, pp. 149-156
-
-
Herrera-Gayol, A.1
Jothy, S.2
-
36
-
-
0035568862
-
Stage-specific Alternative Splicing of CD44 and Alpha 6 Beta 1 Integrin in Colorectal Tumorigenesis
-
Wittig, B. M.; Goebel, R.; Weg-Remers, S.; Pistorius, G.; Feifei, G.; Zeitz, M.; Stallmach, A. Stage-specific Alternative Splicing of CD44 and Alpha 6 Beta 1 Integrin in Colorectal Tumorigenesis. Exp. Mol. Pathol. 2001. 70, 96-102.
-
(2001)
Exp. Mol. Pathol.
, vol.70
, pp. 96-102
-
-
Wittig, B.M.1
Goebel, R.2
Weg-Remers, S.3
Pistorius, G.4
Feifei, G.5
Zeitz, M.6
Stallmach, A.7
-
37
-
-
0035312291
-
The Human XPG Gene: Gene Architecture, Alternative Splicing and Single Nucleotide Polymorphisms
-
Emmert, S.; Schneider, T. D.; Khan, S. G.; Kraemer, K. H. The Human XPG Gene: Gene Architecture, Alternative Splicing and Single Nucleotide Polymorphisms. Nucleic Acids Res. 2001, 29, 1443-1452.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 1443-1452
-
-
Emmert, S.1
Schneider, T.D.2
Khan, S.G.3
Kraemer, K.H.4
-
38
-
-
0033854786
-
Reduced Expression Levels of Nucleotide Excision Repair Genes in Lung Cancer: A Case-Control Analysis
-
Cheng, L.; Spitz, M. R.; Hong, W. K.; Wei, Q. Reduced Expression Levels of Nucleotide Excision Repair Genes in Lung Cancer: A Case-Control Analysis. Carcinogenesis 2000, 21, 1527-1530.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1527-1530
-
-
Cheng, L.1
Spitz, M.R.2
Hong, W.K.3
Wei, Q.4
-
39
-
-
0029832418
-
Reduced DNA Repair Capacity in Lung Cancer Patients
-
Wei, Q.; Cheng, L.; Hong, W. K.; Spitz, M. R. Reduced DNA Repair Capacity in Lung Cancer Patients. Cancer Res. 1996, 56, 4103-4107.
-
(1996)
Cancer Res.
, vol.56
, pp. 4103-4107
-
-
Wei, Q.1
Cheng, L.2
Hong, W.K.3
Spitz, M.R.4
-
40
-
-
0029778770
-
Brain-Derived Neurotrophic Factor Protects Neuroblastoma Cells from Vinblastine Toxicity
-
Scala, S.; Wosikowski, K.; Giannakakou, P.; Valle, P.; Biedler, J. L.; Spengler, B. A.; Lucarelli, E.; Bates, S. E.; Thiele, C. J. Brain-Derived Neurotrophic Factor Protects Neuroblastoma Cells from Vinblastine Toxicity. Cancer Res. 1996, 56, 3737-3742.
-
(1996)
Cancer Res.
, vol.56
, pp. 3737-3742
-
-
Scala, S.1
Wosikowski, K.2
Giannakakou, P.3
Valle, P.4
Biedler, J.L.5
Spengler, B.A.6
Lucarelli, E.7
Bates, S.E.8
Thiele, C.J.9
-
41
-
-
0033522881
-
BrainDerived Neurotrophic Factor Promotes Survival and Chemoprotection of Human Neuroblastoma Cells
-
.Middlemas, D. S.; Kihl, B. K.; Zhou, J.; Zhu, X. BrainDerived Neurotrophic Factor Promotes Survival and Chemoprotection of Human Neuroblastoma Cells. J. Biol. Chem. 1999, 274, 16451-16460.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16451-16460
-
-
Middlemas, D.S.1
Kihl, B.K.2
Zhou, J.3
Zhu, X.4
-
42
-
-
0035836071
-
Human Neuroblastomas with Unfavorable Biologies Express High Levels of BrainDerived Neurotrophic Factor mRNA and a Variety of its Variants
-
Aoyama, M.; Asai, K.; Shishikura, T.; Kawamoto, T.; Miyachi, T.; Yokoi, T.; Togari, H.; Wada, Y.; Kato, T.; Nakagawara, A. Human Neuroblastomas with Unfavorable Biologies Express High Levels of BrainDerived Neurotrophic Factor mRNA and a Variety of its Variants. Cancer Lett. 2001,164, 51-60. .
-
(2001)
Cancer Lett.
, vol.164
, pp. 51-60
-
-
Aoyama, M.1
Asai, K.2
Shishikura, T.3
Kawamoto, T.4
Miyachi, T.5
Yokoi, T.6
Togari, H.7
Wada, Y.8
Kato, T.9
Nakagawara, A.10
-
43
-
-
0032914182
-
Alternative Splicing and Programmed Cell Death
-
Jiang, Z. H.; Wu, J. Y. Alternative Splicing and Programmed Cell Death. Proc. Soc. Exp. Biol. Med. 1999, 220, 64-72.
-
(1999)
Proc. Soc. Exp. Biol. Med.
, vol.220
, pp. 64-72
-
-
Jiang, Z.H.1
Wu, J.Y.2
-
44
-
-
0028168593
-
Ich1, an Ice/ced-3-Related Gene, Encodes both Positive and Negative Regulators of Programmed Cell Death
-
Wang, L.; Miura, M.; Bergeron, L.; Zhu, H.; Yuan, J. Ich1, an Ice/ced-3-Related Gene, Encodes both Positive and Negative Regulators of Programmed Cell Death. Cell 1994, 78, 739-750.
-
(1994)
Cell
, vol.78
, pp. 739-750
-
-
Wang, L.1
Miura, M.2
Bergeron, L.3
Zhu, H.4
Yuan, J.5
-
45
-
-
0033024272
-
Up-regulation of ICH1L Protein by Thromboxane A2 Antagonists Enhances Cisplatin-Induced Apoptosis in Non-Small-Cell LungCancer Cell Lines
-
Fujimura, M.; Kasahara, K.; Shirasaki, H.; Heki, U.; Iwasa, K.; Ueda, A.; Matsuda, T. Up-regulation of ICH1L Protein by Thromboxane A2 Antagonists Enhances Cisplatin-Induced Apoptosis in Non-Small-Cell LungCancer Cell Lines. J. Cancer Res. Clin. Oncol. 1999, 725, 389-394.
-
(1999)
J. Cancer Res. Clin. Oncol.
, vol.725
, pp. 389-394
-
-
Fujimura, M.1
Kasahara, K.2
Shirasaki, H.3
Heki, U.4
Iwasa, K.5
Ueda, A.6
Matsuda, T.7
-
46
-
-
0035843138
-
Modulation of Apoptosis by Procaspase-2 Short Isoform: Selective Inhibition of Chromatin Condensation, Apoptotic Body Formation and Phosphatidylserine Externalization
-
Droin, N.; Rebe, C.; Bichat, F.; Hammann, A.; Bertrand, R.; Solary, E. Modulation of Apoptosis By Procaspase-2 Short Isoform: Selective Inhibition of Chromatin Condensation, Apoptotic Body Formation and Phosphatidylserine Externalization. Oncogens 2001, 20, 260-269.
-
(2001)
Oncogens
, vol.20
, pp. 260-269
-
-
Droin, N.1
Rebe, C.2
Bichat, F.3
Hammann, A.4
Bertrand, R.5
Solary, E.6
-
47
-
-
0023786047
-
Bcl-2 Gene Promotes Haemopoietic Cell Survival and Cooperates with C-Myc to Immortalize Pre-B Cells
-
Vaux, D. L.; Cory, S.; Adams, J. M. Bcl-2 Gene Promotes Haemopoietic Cell Survival and Cooperates With C-Myc to Immortalize Pre-B Cells. Nature 1988, 335, 440-442.
-
(1988)
Nature
, vol.335
, pp. 440-442
-
-
Vaux, D.L.1
Cory, S.2
Adams, J.M.3
-
48
-
-
0032998309
-
Overcoming Bcl-2- And p53-Mediated Resistance in Prostate Cancer
-
DiPaola, R. S.; Aisner, J. Overcoming Bcl-2- and p53-Mediated Resistance in Prostate Cancer. Semin. Oncol. 1999,26, 112-116.
-
(1999)
Semin. Oncol.
, vol.26
, pp. 112-116
-
-
Dipaola, R.S.1
Aisner, J.2
-
49
-
-
0033913693
-
Shanahan, F. Altered Mechanisms of Apoptosis in Colon Cancer: Fas Resistance and Counterattack in the Tumor-Immune Conflict
-
discussion 193-195
-
O'Connell, J.; Bennett, M. W.; Nally, K.; Houston, A.; O'Sullivan, G. C.; Shanahan, F. Altered Mechanisms of Apoptosis in Colon Cancer: Fas Resistance and Counterattack in the Tumor-Immune Conflict. Ann. N. Y. Acad. Sei. 2000, 910, 178-192; discussion 193-195.
-
(2000)
Ann. N. Y. Acad. Sei.
, vol.910
, pp. 178-192
-
-
O'Connell, J.1
Bennett, M.W.2
Nally, K.3
Houston, A.4
O'Sullivan, G.C.5
-
50
-
-
0022546957
-
Analysis of the Structure, Transcripts, and Protein Products of Bcl-2, the Gene Involved in Human Follicular Lymphoma
-
Tsujimoto, Y.; Croce, C. M. Analysis of the Structure, Transcripts, and Protein Products of Bcl-2, The Gene Involved in Human Follicular Lymphoma. Proc. Natl. Acad. Sei. U. S. A. 1986, 83, 5214-5218.
-
(1986)
Proc. Natl. Acad. Sei. U. S. A.
, vol.83
, pp. 5214-5218
-
-
Tsujimoto, Y.1
Croce, C.M.2
-
51
-
-
0032719052
-
Tamoxifen-Induced Apoptosis in Breast Cancer Cells Relates to Down- Regulation of Bcl-2, but not Bax and Bcl-x(L), without Alteration of p53 Protein Levels
-
Zhang, G. J.; Kimijima, I.; Onda, M.; Kanno, M.; Sato, H.; Watanabe, T.; Tsuchiya, A.; Abe, R.; Takenoshita, S. Tamoxifen-Induced Apoptosis in Breast Cancer Cells Relates to Down- Regulation of Bcl-2, but not Bax and Bcl-x(L), without Alteration of p53 Protein Levels. Clin. Cancer Res. 1999,5, 2971-2977.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2971-2977
-
-
Zhang, G.J.1
Kimijima, I.2
Onda, M.3
Kanno, M.4
Sato, H.5
Watanabe, T.6
Tsuchiya, A.7
Abe, R.8
Takenoshita, S.9
-
52
-
-
0027282044
-
Bcl-x, a Bcl-2-Related Gene that Functions as a Dominant .Regulator of Apoptotic Cell Death
-
Boise, L.H.; Gonzalez-Garcia, M.; Postema, C. E.; Ding, L.; Lindsten, T.; Turka, L. A.; Mao, X.; Nùnez, G.; Thompson, C.B. Bcl-x, a Bcl-2-Related Gene that Functions as a Dominant .Regulator of Apoptotic Cell Death. Cell 1993, 74, 597-608.
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.H.1
Gonzalez-Garcia, M.2
Postema, C.E.3
Ding, L.4
Lindsten, T.5
Turka, L.A.6
Mao, X.7
Nùnez, G.8
Thompson, C.B.9
-
53
-
-
0029919668
-
Immunohistochemical. Analysis of Bcl-2, Bax, Bcl-x, and Mcl-1 Expression in Prostate Cancers
-
Krajewska, M.; Krajewski, S.; Epstein, J. I.; Shabaik, A.; Sauvageot, J.; Song, K.; Kitada, S.; Reed, J. C. Immunohistochemical. Analysis of Bcl-2, Bax, Bcl-x, and Mcl-1 Expression in Prostate Cancers. Am. J. Pathol. 1996,148, 1567-1576.
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 1567-1576
-
-
Krajewska, M.1
Krajewski, S.2
Epstein, J.I.3
Shabaik, A.4
Sauvageot, J.5
Song, K.6
Kitada, S.7
Reed, J.C.8
-
54
-
-
0031939573
-
Bcl-2, Bax, Bcl-xL, and Bcl-xS Expression in Normal and Neoplastic Ovarian Tissues
-
Marone, M.; Scambia, G.; Mozzetti, S.; Ferrandina, G.; lacovella, S.; De Pasqua, A.; Benedetti-Panici, P.; Mancuso, S. Bcl-2, Bax, Bcl-xL, And Bcl-xS Expression in Normal and Neoplastic Ovarian Tissues. Clin. Cancer Res. 1998, 4, 517-524.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 517-524
-
-
Marone, M.1
Scambia, G.2
Mozzetti, S.3
Ferrandina, G.4
Lacovella, S.5
De Pasqua, A.6
Benedetti-Panici, P.7
Mancuso, S.8
-
55
-
-
0344614011
-
Bcl-2, bax and bcl-xL Expression in Human Sensitive and Resistant Leukemia Cell Lines
-
Nuessler, V.; Stotzer, O.; Gullis, E.; Pelka-Fleischer, R.; Pogrebniak, A.; Gieseler, F.; Wilmanns, W. Bcl-2, bax and bcl-xL Expression in Human Sensitive and Resistant Leukemia Cell Lines. Leukemia 1999, 13, 1864-1872.
-
(1999)
Leukemia
, vol.13
, pp. 1864-1872
-
-
Nuessler, V.1
Stotzer, O.2
Gullis, E.3
Pelka-Fleischer, R.4
Pogrebniak, A.5
Gieseler, F.6
Wilmanns, W.7
-
56
-
-
0030795866
-
Bcl-2 and BclxL can Differentially Block Chemotherapy-Induced Cell Death
-
Simonian, P. L.; Grillot, D. A.; Nunez, G. Bcl-2 and BclxL can Differentially Block Chemotherapy-Induced Cell Death. Blood 1997, 90, 1208-1216.
-
(1997)
Blood
, vol.90
, pp. 1208-1216
-
-
Simonian, P.L.1
Grillot, D.A.2
Nunez, G.3
-
57
-
-
0031907215
-
Targeting Cancer Cell Death with a Bcl-XS Adenovirus
-
Han, J. S.; Nunez, G.; Wicha, M. S.; Clarke, M. F. Targeting Cancer Cell Death with a Bcl-XS Adenovirus. Springer Semin. Immunopathol. 1998, 19, 279-288.
-
(1998)
Springer Semin. Immunopathol.
, vol.19
, pp. 279-288
-
-
Han, J.S.1
Nunez, G.2
Wicha, M.S.3
Clarke, M.F.4
-
58
-
-
0033526938
-
Inhibition of Bcl-xL Expression Sensitizes Normal Human Keratinocytes and Epithelial Cells to Apoptotic Stimuli
-
Taylor, J. K.; Zhang, Q. Q.; Monia, B. P.; Marcusson, E. G.; Dean, N. M. Inhibition of Bcl-xL Expression Sensitizes Normal Human Keratinocytes and Epithelial Cells to Apoptotic Stimuli. Oncogene 1999,18, 4495-4504.
-
(1999)
Oncogene
, vol.18
, pp. 4495-4504
-
-
Taylor, J.K.1
Zhang, Q.Q.2
Monia, B.P.3
Marcusson, E.G.4
Dean, N.M.5
-
59
-
-
0028979438
-
Overexpression of Bcl-XS Sensitizes MCF-7 Cells to Chemotherapy-Induced Apoptosis
-
Sumantran, V. N.; Ealovega, M. W.; Nunez, G.; Clarke, M. F.; Wicha, M. S. Overexpression of Bcl-XS Sensitizes MCF-7 Cells to Chemotherapy-Induced Apoptosis. Cancer Res. 1995,55, 2507-2510.
-
(1995)
Cancer Res.
, vol.55
, pp. 2507-2510
-
-
Sumantran, V.N.1
Ealovega, M.W.2
Nunez, G.3
Clarke, M.F.4
Wicha, M.S.5
-
60
-
-
0029852727
-
Enforced Expression of Bcl-XS Induces Differentiation and Sensitizes Chronic Myelogenous Leukemia-Blast Crisis K562 Cells to 1-Beta-D-Arabinofuranosylcytosine-Mediated Differentiation and Apoptosis
-
Ray, S.; Bullock, G.; Nunez, G.; Tang, C.; Ibrado, A. M.; Huang, Y.; Bhalla, K. Enforced Expression of Bcl-XS Induces Differentiation and Sensitizes Chronic Myelogenous Leukemia-Blast Crisis K562 Cells to 1-Beta-D-Arabinofuranosylcytosine-Mediated Differentiation and Apoptosis. Cell Growth Differ. 1996, 7, 1617-1623.
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 1617-1623
-
-
Ray, S.1
Bullock, G.2
Nunez, G.3
Tang, C.4
Ibrado, A.M.5
Huang, Y.6
Bhalla, K.7
-
61
-
-
0032518787
-
Bim: A Novel Member of the Bcl-2 Family that Promotes Apoptosis
-
O'Connor, L.; Strasser, A.; O'Reilly, L. A.; Hausmann, G.; Adams, J. M.; Cory, S.; Huang, D. C. Bim: A Novel Member of the Bcl-2 Family that Promotes Apoptosis. EMBO J. 1998, 17, 384-395.
-
(1998)
EMBO J.
, vol.17
, pp. 384-395
-
-
O'Connor, L.1
Strasser, A.2
O'Reilly, L.A.3
Hausmann, G.4
Adams, J.M.5
Cory, S.6
Huang, D.C.7
-
62
-
-
0027166048
-
Bcl-2 Heterodimerizes in Vivo with A Conserved Homolog, Bax, that Accelerates Programmed Cell Death
-
Oltvai, Z. N.; Milliman, C. L.; Korsmeyer, S. J. Bcl-2 Heterodimerizes In Vivo With A Conserved Homolog, Bax, that Accelerates Programmed Cell Death. Cell 1993, 74, 609-619.
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
63
-
-
0034074374
-
Significance of Apoptosis and Apoptotic-Related Proteins, Bcl-2, and Bax in Primary Breast Cancer
-
VVu, J.; Shao, Z. M.; Shen, Z. Z.; Lu, J.S.; Han, Q. X.; Fontana, J. A.; Barsky, S. H. Significance of Apoptosis and Apoptotic-Related Proteins, Bcl-2, and Bax in Primary Breast Cancer. Breast J. 2000, 6, 44-52.
-
(2000)
Breast J.
, vol.6
, pp. 44-52
-
-
Vvu, J.1
Shao, Z.M.2
Shen, Z.Z.3
Lu, J.S.4
Han, Q.X.5
Fontana, J.A.6
Barsky, S.H.7
-
64
-
-
0032496238
-
A Novel Splice Variant of the Cell Death-Promoting Protein BAX
-
Zhou, M.; Demo, S. D.; McClure, T. N.; Crea, R.; Bitler, C. M. A Novel Splice Variant of the Cell Death-Promoting Protein BAX. J. Biol. Chem. 1998,273, 11930-11936.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 11930-11936
-
-
Zhou, M.1
Demo, S.D.2
McClure, T.N.3
Crea, R.4
Bitler, C.M.5
-
65
-
-
0029024368
-
Mapping of the Human BAX Gene to Chromosome 19q13.3-Q13.4 and Isolation of a Novel Alternatively Spliced Transcript, BAX Delta
-
Apte, S. S.; Mattel, M. G.; Olsen, B. R. Mapping of the Human BAX Gene to Chromosome 19q13.3-Q13.4 and Isolation of a Novel Alternatively Spliced Transcript, BAX Delta Genomics 1995, 26, 592-594.
-
(1995)
Genomics
, vol.26
, pp. 592-594
-
-
Apte, S.S.1
Mattel, M.G.2
Olsen, B.R.3
-
66
-
-
0034574642
-
Induction of Apoptosis in Head-and-Neck Squamous Carcinoma Cells by Gamma-Irradiation and Bleomycin is p53-Independent
-
Patel, V.; Ensley, J. F.; Gutkind, J. S.; Yeudall, W. A. Induction of Apoptosis in Head-and-Neck Squamous Carcinoma Cells by Gamma-Irradiation and Bleomycin is p53-Independent. Int. J. Cancer 2000, 88, 737-743.
-
(2000)
Int. J. Cancer
, vol.88
, pp. 737-743
-
-
Patel, V.1
Ensley, J.F.2
Gutkind, J.S.3
Yeudall, W.A.4
-
67
-
-
0032055536
-
Gene Expression by Single Reed-Sternberg Cells: Pathways of Apoptosis and Activation
-
Messineo, C.; Jamerson, M. H.; Hunter, E.; Braziel, R.; Bagg, A.; Irving, S. G.; Cossman, J. Gene Expression by Single Reed-Sternberg Cells: Pathways of Apoptosis and Activation. Blood 1998, 91, 2443-2451.
-
(1998)
Blood
, vol.91
, pp. 2443-2451
-
-
Messineo, C.1
Jamerson, M.H.2
Hunter, E.3
Braziel, R.4
Bagg, A.5
Irving, S.G.6
Cossman, J.7
-
68
-
-
0034696814
-
Characterization of Bax-Sigma, a Cell Death-Inducing Isoform of Bax
-
Schmitt, E.; Paquet, C.; Beauchemin, M.; Dever-Bertrand, J.; Bertrand, R. Characterization of Bax-Sigma, a Cell Death-Inducing Isoform of Bax. Blochem. Biophys. Res. Commun. 2000, 270, 868-879.
-
(2000)
Blochem. Biophys. Res. Commun.
, vol.270
, pp. 868-879
-
-
Schmitt, E.1
Paquet, C.2
Beauchemin, M.3
Dever-Bertrand, J.4
Bertrand, R.5
-
69
-
-
0029909361
-
Fas Splicing Variants and their Effect on Apoptosis
-
Ruberti, G.; Cascino, I.; Papoff, G.; Eramo, A. Fas Splicing Variants and their Effect on Apoptosis. Adv. Exp. Med. Biol. 1996, 406, 125-134.
-
(1996)
Adv. Exp. Med. Biol.
, vol.406
, pp. 125-134
-
-
Ruberti, G.1
Cascino, I.2
Papoff, G.3
Eramo, A.4
-
70
-
-
0030940538
-
LARD: A New Lymphoid-Specific Death Domain Containing Receptor Regulated by Alternative Pre-mRNA Splicing
-
Screaton, G.R.; Xu, X.N.; Olsen, A.L.; Cowper, A.E.; Tan, R.; McMichael, A.J.; Bell, J. I. LARD: A New Lymphoid-Specific Death Domain Containing Receptor Regulated by Alternative Pre-mRNA Splicing. Proc. Natl. Acad. Sei. U. S. A. 1997, 94, 4615-4619.
-
(1997)
Proc. Natl. Acad. Sei. U. S. A.
, vol.94
, pp. 4615-4619
-
-
Screaton, G.R.1
Xu, X.N.2
Olsen, A.L.3
Cowper, A.E.4
Tan, R.5
McMichael, A.J.6
Bell, J.I.7
-
71
-
-
0030839168
-
The FHIT Gene is Alternatively Spliced in Normal Kidney and Renal Cell Carcinoma
-
Luan, X.; Shi, G.; Zohouri, M.; Paradee, W.; Smith, D. L; Decker, H. J.; Cannizzaro, L. A. The FHIT Gene is Alternatively Spliced in Normal Kidney and Renal Cell Carcinoma. Oncogens 1997, 15, 79-86.
-
(1997)
Oncogens
, vol.15
, pp. 79-86
-
-
Luan, X.1
Shi, G.2
Zohouri, M.3
Paradee, W.4
Smith, D.L.5
Decker, H.J.6
Cannizzaro, L.A.7
-
72
-
-
0033159536
-
Alternative Splicing, but not Allelic Loss, of the FHIT Gene Increases with Development of Lung Cancer
-
Sato, H.; Hiyama, K.; Ishioka, S.; Maeda, H.; Yamakido, M. Alternative Splicing, but not Allelic Loss, of the FHIT Gene Increases with Development of Lung Cancer. Int. J. Oncol. 1999, 15, 81-88.
-
(1999)
Int. J. Oncol.
, vol.15
, pp. 81-88
-
-
Sato, H.1
Hiyama, K.2
Ishioka, S.3
Maeda, H.4
Yamakido, M.5
-
73
-
-
0033552641
-
The p53 Gene Family
-
Kaelin, W. G., Jr. The p53 Gene Family. Oncogene 1999, 18, 7701-7705.
-
(1999)
Oncogene
, vol.18
, pp. 7701-7705
-
-
Kaelin Jr., W.G.1
-
74
-
-
0030812331
-
Monoallelically Expressed Gene Related to p53 at Ip36, a Region Frequently Deleted in Neuroblastoma and other Human Cancers
-
Kaghad, M.; Bonnet, H.; Yang, A.; Creancier, L.; Biscan, J.C.; Valent, A.; Minty, A.; Chalon, P.; Lelias, J. M.; Dumont, X.; Ferrara, P.; McKeon, F.; Caput, D. Monoallelically Expressed Gene Related to p53 at Ip36, a Region Frequently Deleted in Neuroblastoma and other Human Cancers. Cell 1997, 90, 809-819.
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
Creancier, L.4
Biscan, J.C.5
Valent, A.6
Minty, A.7
Chalon, P.8
Lelias, J.M.9
Dumont, X.10
Ferrara, P.11
McKeon, F.12
Caput, D.13
-
75
-
-
17744386129
-
Transactivation-Deficient p73alpha (p73Deltaexon2) Inhibits Apoptosis and Competes with p53
-
Fillippovich, I.; Sorokina, N.; Gatei, M.; Haupt, Y.; Hobson, K.; Moallem, E.; Spring, K.; Mould, M.; McGuckin, M. A.; Lavin, M. F.; Khanna, K. K. Transactivation-Deficient p73alpha (p73Deltaexon2) Inhibits Apoptosis and Competes with p53. Oncogene 2001,20,514-522.
-
(2001)
Oncogene
, pp. 514-522
-
-
Fillippovich, I.1
Sorokina, N.2
Gatei, M.3
Haupt, Y.4
Hobson, K.5
Moallem, E.6
Spring, K.7
Mould, M.8
McGuckin, M.A.9
Lavin, M.F.10
Khanna, K.K.11
-
76
-
-
0033381054
-
Regulation and Activation of p53 and its Family Members
-
Lohrum, M. A.; Vousden, K. H. Regulation and Activation of p53 and its Family Members. Cell Death Differ. 1999, 6, 1162-1168.
-
(1999)
Cell Death Differ.
, vol.6
, pp. 1162-1168
-
-
Lohrum, M.A.1
Vousden, K.H.2
-
77
-
-
0030905284
-
Mdm2 Promotes the Rapid Degradation of p53
-
Haupt, Y.; Maya, R.; Kazaz, A.; Oren, M. Mdm2 Promotes the Rapid Degradation of p53. Nature 1997, 387, 296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
78
-
-
0030965946
-
Regulation of p53 Stability by MDM2
-
Kubbutat, M. H.; Jones, S. N.; Vousden, K. H. Regulation of p53 Stability by MDM2. Nature 1997, 387, 299-303.
-
(1997)
Nature
, vol.387
, pp. 299-303
-
-
Kubbutat, M.H.1
Jones, S.N.2
Vousden, K.H.3
-
79
-
-
0027325132
-
Oncoprotein MDM2 Conceals the Activation Domain of Tumour Suppressor p53
-
Oliner, J. D.; Pietenpol, J. A.; Thiagalingam, S.; Gyuris, J.; Kinzler, K. W.; V.ogelstein, B. Oncoprotein MDM2 Conceals the Activation Domain of Tumour Suppressor p53. Nature 1993, 362, 857-860.
-
(1993)
Nature
, vol.362
, pp. 857-860
-
-
Oliner, J.D.1
Pietenpol, J.A.2
Thiagalingam, S.3
Gyuris, J.4
Kinzler, K.W.5
V.ogelstein, B.6
-
80
-
-
0032520061
-
Short Alternative Splice Transcripts of the MDM2 Oncogene Correlate to Malignancy in Human Astrocytic Neoplasms
-
Matsumoto, R.; Tada, M.; Nozaki, M.; Zhang, C. L.; Sawamura, Y.; Abe, H. Short Alternative Splice Transcripts of the MDM2 Oncogene Correlate To Malignancy in Human Astrocytic Neoplasms. Cancer Res. 1998, 58, 609-613.
-
(1998)
Cancer Res.
, vol.58
, pp. 609-613
-
-
Matsumoto, R.1
Tada, M.2
Nozaki, M.3
Zhang, C.L.4
Sawamura, Y.5
Abe, H.6
-
81
-
-
0029824669
-
Alternatively Spliced mdm2 Transcripts with Loss of p53 Binding Domain Sequences: Transforming Ability and Frequent Detection in Human Cancer
-
Sigalas, I.; Calvert, A. H.; Anderson, J. J.; Neal, D. E. Lunée, J. Alternatively Spliced mdm2 Transcripts with Loss of p53 Binding Domain Sequences: Transforming Ability and Frequent Detection in Human Cancer. Nat. Med.1996,2, 912-917.
-
(1996)
Nat. Med.
, vol.2
, pp. 912-917
-
-
Sigalas, I.1
Calvert, A.H.2
Anderson, J.J.3
Neal, D.E.4
Lunée, J.5
-
82
-
-
0035300512
-
Alternative and Aberrant Messenger RNA Splicing of the mdm2 Oncogene in Invasive Breast Cancer
-
Lukas, J.; Gao, D. Q.; Keshmeshian, M.; Wen; W. H.; Tsao-Wei, D.; Rosenberg, S.; Press, M. F. Alternative and Aberrant Messenger RNA Splicing of the mdm2 Oncogene in Invasive Breast Cancer. Cancer Res. 2001, 61, 3212-3219.
-
(2001)
Cancer Res.
, vol.61
, pp. 3212-3219
-
-
Lukas, J.1
Gao, D.Q.2
Keshmeshian, M.3
Wen, W.H.4
Tsao-Wei, D.5
Rosenberg, S.6
Press, M.F.7
-
83
-
-
1042274013
-
Amplification of the MDM2 gene, but not Expression of Splice Variants of MDM2 MRNA, is Associated with Prognosis in Soft Tissue Sarcoma
-
Barte!, F.; Meye, A.; Wuri, P.; Kappler, M.; Bache, M.; Lautenschlager; C.; Grunbaum, U.; Schmidt, H.; Taubert, H. Amplification of the MDM2 gene, but not Expression of Splice Variants of MDM2 MRNA, is Associated with Prognosis in Soft Tissue Sarcoma./J. J. Cancer2001, 95, 168-175.
-
(2001)
/J. J. Cancer
, vol.95
, pp. 168-175
-
-
Barte, F.1
Meye, A.2
Wuri, P.3
Kappler, M.4
Bache, M.5
Lautenschlager, C.6
Grunbaum, U.7
Schmidt, H.8
Taubert, H.9
-
84
-
-
0029953670
-
Multiple Enzyme Forms from a Single Gene and their Relation to Cancer
-
Keppler, D.; Sloane, B. F. Cathepsin B: Multiple Enzyme Forms from a Single Gene and their Relation to Cancer. Enzyme Protein 1996, 49, 94-105.
-
(1996)
Enzyme Protein
, vol.49
, pp. 94-105
-
-
Keppler, D.1
Sloane, B.F.2
Cathepsin, B.3
-
85
-
-
0035033242
-
Expression of Cathepsin B and Cystatin C in Human Breast Cancer
-
Yano, M.; Hirai, K.; Naito, Z.; Yokoyama, M.; Ishiwata, T.; Shiraki, Y.; Inokuchi, M.; Asano, G. Expression of Cathepsin B and Cystatin C in Human Breast Cancer. Surg. Today 2001, 31, 385-389.
-
(2001)
Surg. Today
, vol.31
, pp. 385-389
-
-
Yano, M.1
Hirai, K.2
Naito, Z.3
Yokoyama, M.4
Ishiwata, T.5
Shiraki, Y.6
Inokuchi, M.7
Asano, G.8
-
86
-
-
0035897568
-
Activity, Function, and Gene Regulation of the Catalytic Subunit ofTelomerase(hTERT)
-
Poole, J. C.; Andrews, L. G.; Tollefsbol, T. O. Activity, Function, and Gene Regulation of the Catalytic Subunit ofTelomerase(hTERT). Gene 2001, 269, 1-12.
-
(2001)
Gene
, vol.269
, pp. 1-12
-
-
Poole, J.C.1
Andrews, L.G.2
Tollefsbol, T.O.3
-
87
-
-
0034048726
-
Adenoviral Expression of p53 Represses Telomerase Activity through Down-Regulation of Human Telomerase Reverse Transcriptase Transcription
-
Kanaya, T.; Kyo, S.; Hamada, K.; Takakura, M.; Kitagawa, Y.; Harada, H.; Inoue, M. Adenoviral Expression of p53 Represses Telomerase Activity through Down-Regulation Of Human Telomerase Reverse Transcriptase Transcription. Clin. Cancer Res. 2000,0, 1239-1247.
-
(2000)
Clin. Cancer Res.
, vol.0
, pp. 1239-1247
-
-
Kanaya, T.1
Kyo, S.2
Hamada, K.3
Takakura, M.4
Kitagawa, Y.5
Harada, H.6
Inoue, M.7
-
88
-
-
0030819894
-
Telomerase Catalytic Subunit Homologs from Fission Yeast and Human
-
Nakamura, T. M.; Morin, G. B.; Chapman, K. B.; Weinrich, S. L.; Andrews, W. H.; Lingner, J.; Harley, C. B.; Cech, T. R. Telomerase Catalytic Subunit Homologs from Fission Yeast and Human. Science 1997, 277, 955-959.
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
Weinrich, S.L.4
Andrews, W.H.5
Lingner, J.6
Harley, C.B.7
Cech, T.R.8
-
89
-
-
0030789537
-
Telomerase Activity in Human Gynaecological Malignancies
-
Gorham, H.; Yoshida, K.; Sugino, T.; Marsh, G.; Manek, S.; Charnock, M.; Tarin, D.; Goodison, S. Telomerase Activity in Human Gynaecological Malignancies. J. Clin. Pathol. 1997, 50, 501-504.
-
(1997)
J. Clin. Pathol.
, vol.50
, pp. 501-504
-
-
Gorham, H.1
Yoshida, K.2
Sugino, T.3
Marsh, G.4
Manek, S.5
Charnock, M.6
Tarin, D.7
Goodison, S.8
-
90
-
-
0030474615
-
Telorherase Activity in Gynecological Tumors
-
Kyo, S.; Kanaya, T.; Ishikawa, H.; Ueno, H.; Inoue, M. Telorherase Activity in Gynecological Tumors. Clin. Cancer Res. 1996, 2, 2023-2028.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 2023-2028
-
-
Kyo, S.1
Kanaya, T.2
Ishikawa, H.3
Ueno, H.4
Inoue, M.5
-
91
-
-
0033559588
-
Expression of Human Telomerase Subunits in Ovarian Malignant, Borderline and Benign Tumors
-
Kyo, S.; Kanaya, T.; Takakura, M.; Tanaka, M.; Yamashita, A.; Inoue, H.; Inoue, M. Expression of Human Telomerase Subunits in Ovarian Malignant, Borderline and Benign Tumors. Int. J. Cancer 1999, 80, 804-809.
-
(1999)
Int. J. Cancer
, vol.80
, pp. 804-809
-
-
Kyo, S.1
Kanaya, T.2
Takakura, M.3
Tanaka, M.4
Yamashita, A.5
Inoue, H.6
Inoue, M.7
-
92
-
-
0033524343
-
Human Telomerase Reverse Transcriptase as a Critical Determinant of Telomerase Activity in Normal and Malignant Endometrial Tissues
-
Kyo, S.; Kanaya, T.; Takakura, M.; Tanaka, M.; Inoue, M. Human Telomerase Reverse Transcriptase as a Critical Determinant of Telomerase Activity in Normal and Malignant Endometrial Tissues. Int. J. Cancer 1999, 80, 60-63.
-
(1999)
Int. J. Cancer
, vol.80
, pp. 60-63
-
-
Kyo, S.1
Kanaya, T.2
Takakura, M.3
Tanaka, M.4
Inoue, M.5
-
93
-
-
17144471436
-
Proliferation-Associated Regulation of Telomerase Activity in Human Endometrium and its Potential Implication in Early Cancer Diagnosis
-
Saito, T.; Schneider, A.; Martel, N.; Mizumoto, H.; Bulgay-Moerschel, M.; Kudo, R.; Nakazawa, H. Proliferation-Associated Regulation of Telomerase Activity in Human Endometrium and its Potential Implication in Early Cancer Diagnosis. Biochem. Biophys. Res. Commun. 1997,231, 610-614.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.231
, pp. 610-614
-
-
Saito, T.1
Schneider, A.2
Martel, N.3
Mizumoto, H.4
Bulgay-Moerschel, M.5
Kudo, R.6
Nakazawa, H.7
-
94
-
-
0033988011
-
Regulation of Telomerase by Alternate Splicing of Human Telomerase Reverse Transcriptase (hTERT) in Normal and Neoplastic Ovary, Endometrium and Myometrium
-
Ulaner, G. A.; Hu, J. F.; Vu, T. H.; Oruganti, H.; Giudice, L.C.; Hoffman, A. R. Regulation of Telomerase by Alternate Splicing of Human Telomerase Reverse Transcriptase (hTERT) in Normal and Neoplastic Ovary, Endometrium and Myometrium. Int. J. Cancer 2000, 85, 330-335.
-
(2000)
Int. J. Cancer
, vol.85
, pp. 330-335
-
-
Ulaner, G.A.1
Hu, J.F.2
Vu, T.H.3
Oruganti, H.4
Giudice, L.C.5
Hoffman, A.R.6
-
95
-
-
0031150017
-
The Role of Phosphotyrosine Phosphatases in Haematopoietic Cell Signal Transduction
-
Frearson, J. A.; Alexander, D. R. The Role of Phosphotyrosine Phosphatases in Haematopoietic Cell Signal Transduction. Bioessays 1997, 19, 417-427.
-
(1997)
Bioessays
, vol.19
, pp. 417-427
-
-
Frearson, J.A.1
Alexander, D.R.2
-
96
-
-
0026547356
-
Protein Tyrosine Phosphatase Containing SH2 Domains: Characterization, Preferential Expression in Hematopoietic Cells, and Localization to Human Chromosome 12pl2-pl3
-
Yi, T. L.; Cleveland, J. L.; Ihle, J. N. Protein Tyrosine Phosphatase Containing SH2 Domains: Characterization, Preferential Expression in Hematopoietic Cells, and Localization to Human Chromosome 12pl2-pl3. Mol. Cell Biol. 1992, 12, 836-846.
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 836-846
-
-
Yi, T.L.1
Cleveland, J.L.2
Ihle, J.N.3
-
97
-
-
0034703285
-
RNA Hyperediting and Alternative Splicing of Hematopoietic Cell Phosphatase (PTPN6) Gene in Acute Myeloid Leukemia
-
Beghini, A.; Ripamonti, C. B.; Peterlongo, P.; Roversi, G.; Cairoli, R.; Morra, E.; Larizza, L. RNA Hyperediting and Alternative Splicing of Hematopoietic Cell Phosphatase (PTPN6) Gene in Acute Myeloid Leukemia. Hum. Mol. Genet. 2000, 9, 2297-2304.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2297-2304
-
-
Beghini, A.1
Ripamonti, C.B.2
Peterlongo, P.3
Roversi, G.4
Cairoli, R.5
Morra, E.6
Larizza, L.7
-
98
-
-
0008290616
-
Diverse Functions of JNK Signaling and c-Jun in Stress Response and Apoptosis
-
Leppa, S.; Bohmann, D. Diverse Functions of JNK Signaling and c-Jun in Stress Response and Apoptosis. Oncogene 1999, 18, 6158-6162.
-
(1999)
Oncogene
, vol.18
, pp. 6158-6162
-
-
Leppa, S.1
Bohmann, D.2
-
99
-
-
0032980723
-
The Jun Kinase 2 Isoform is Preferentially Required for Epidermal Growth FactorInduced Transformation of Human A549 Lung Carcinoma Cells
-
Best, F.; McKay, R.; Bost, M.; Potapova, O.; Dean, N. M.; Mercola, D. The Jun Kinase 2 Isoform is Preferentially Required for Epidermal Growth FactorInduced Transformation of Human A549 Lung Carcinoma Cells. Mol. Cell Biol. 1999,19, 1938-1949.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 1938-1949
-
-
Best, F.1
McKay, R.2
Bost, M.3
Potapova, O.4
Dean, N.M.5
Mercola, D.6
-
100
-
-
0030611189
-
C-Jun NH2-Terminal Kinase Regulation of the Apoptotic Response of Small Cell Lung Cancer Cells to Ultraviolet Radiation
-
Butterfield, L.; Storey, B.; Maas, L.; Heasley, L. E. c-Jun NH2-Terminal Kinase Regulation of the Apoptotic Response of Small Cell Lung Cancer Cells to Ultraviolet Radiation. J. Biol. Chem. 1997,272, 10110-10116.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10110-10116
-
-
Butterfield, L.1
Storey, B.2
Maas, L.3
Heasley, L.E.4
-
101
-
-
0029885419
-
Sélective Interaction of JNK Protein Kinase Isoforms with Transcription Factors
-
Gupta, S.; Barrett, T.; Whitmarsh, A. J.; Cavanagh, J.; Sluss, H. K.; Derijard, B.; Dàvis, R. J. Sélective Interaction of JNK Protein Kinase Isoforms with Transcription Factors. EMBO J. 1996,15, 2760-2770.
-
(1996)
EMBO J.
, vol.15
, pp. 2760-2770
-
-
Gupta, S.1
Barrett, T.2
Whitmarsh, A.J.3
Cavanagh, J.4
Sluss, H.K.5
Derijard, B.6
Dàvis, R.J.7
-
102
-
-
0030955765
-
Regulation of Apoptosis and Cell Cycle Arrest by Zacl, a Novel Zinc Finger Protein Expressed in the Pituitary Gland and the Brain
-
Spengler, D.; Villalba, M.; Hoffmann, A.; Pantaloni, C.; Houssami, S.; Bockaert, J.; Journot, L. Regulation of Apoptosis and Cell Cycle Arrest by Zacl, a Novel Zinc Finger Protein Expressed in the Pituitary Gland and the Brain. EMBO J. 1997,16, 2814-2825.
-
(1997)
EMBO J.
, vol.16
, pp. 2814-2825
-
-
Spengler, D.1
Villalba, M.2
Hoffmann, A.3
Pantaloni, C.4
Houssami, S.5
Bockaert, J.6
Journot, L.7
-
103
-
-
0033536226
-
Loss of Expression of the Candidate Tumor Suppressor Gene ZAC in Breast Cancer Cell Lines and Primary Tumors
-
Bilanges, B.; Varrault, A.; Basyuk, E.; Rodriguez, C.; Mazumdar, A.; Pantaloni, C.; Bockaert, J.; Theillet, C.; Spengler, D.; Journot, L. Loss of Expression of the Candidate Tumor Suppressor Gene ZAC in Breast Cancer Cell Lines and Primary Tumors. Oncogens 1999, 18, 3979-3988.
-
(1999)
Oncogens
, vol.18
, pp. 3979-3988
-
-
Bilanges, B.1
Varrault, A.2
Basyuk, E.3
Rodriguez, C.4
Mazumdar, A.5
Pantaloni, C.6
Bockaert, J.7
Theillet, C.8
Spengler, D.9
Journot, L.10
-
104
-
-
0035826177
-
Alternative Splicing of the Imprinted Candidate Tumor Suppressor Gene ZAC Regulates its Antiproliferative and DNA Binding Activities
-
Bilanges, B.; Varrault, A.; Mazumdar, A.; Pantaloni, C.; Hoffmann, A.; Bockaert, J.; Spengler, D.; Journot, L. Alternative Splicing of the Imprinted Candidate Tumor Suppressor Gene ZAC Regulates its Antiproliferative and DNA Binding Activities. Oncogene 2001, 20, 1246-1253.
-
(2001)
Oncogene
, vol.20
, pp. 1246-1253
-
-
Bilanges, B.1
Varrault, A.2
Mazumdar, A.3
Pantaloni, C.4
Hoffmann, A.5
Bockaert, J.6
Spengler, D.7
Journot, L.8
-
105
-
-
0035083604
-
Herceptin: From the Bench to the Clinic
-
Colomer, R.; Shamon, L.A.; Tsai, M.S.; Lupu, R. Herceptin: from the Bench to the Clinic. Cancer Invest. 2001,19, 49-56.
-
(2001)
Cancer Invest.
, vol.19
, pp. 49-56
-
-
Colomer, R.1
Shamon, L.A.2
Tsai, M.S.3
Lupu, R.4
-
106
-
-
0027468645
-
A Truncated Intracellular HER2/Neu Receptor Produced by Alternative RNA Processing Affects Growth of Human Carcinoma Cells
-
Scott, G. K.; Robles, R.; Park, J. wl; Montgomery, P. A.; Daniel, J.; Holmes, W. E.; Lee, J.; Keller, G. A.; Li, W. L.; Fendly, B. M.; et al. A Truncated Intracellular HER2/Neu Receptor Produced by Alternative RNA Processing Affects Growth of Human Carcinoma Cells. Afol. Cell Biol. 1993, 13, 2247-2257.
-
(1993)
Afol. Cell Biol.
, vol.13
, pp. 2247-2257
-
-
Scott, G.K.1
Robles, R.2
Wl, P.J.3
Montgomery, P.A.4
Daniel, J.5
Holmes, W.E.6
Lee, J.7
Keller, G.A.8
Li, W.L.9
Fendly, B.M.10
-
107
-
-
0032850779
-
The HER-2/neu Receptor Tyrosine Kinase Gene Encodes a Secreted Autoinhibitor
-
Doherty, J. K.; Bond, C.; Jardim, A.; Adelman, J. P.; Clinton, G. M. The HER-2/neu Receptor Tyrosine Kinase Gene Encodes a Secreted Autoinhibitor. Proc. Natl. Acad. Sei. U. S. A. 1999, 96, 10869-10874.
-
(1999)
Proc. Natl. Acad. Sei. U. S. A.
, vol.96
, pp. 10869-10874
-
-
Doherty, J.K.1
Bond, C.2
Jardim, A.3
Adelman, J.P.4
Clinton, G.M.5
-
108
-
-
0035912086
-
Expression of a Truncated 100 kDa HER2 Splice Variant Acts as an Endogenous Inhibitor of Tumour Cell Proliferation
-
Aigner, A.; Juhl, H.; Malerczyk, C.; Tkybusch, A.; Benz, C. C.; Czubayko, F. Expression of a Truncated 100 kDa HER2 Splice Variant Acts as an Endogenous Inhibitor of Tumour Cell Proliferation. Oncogene 2001, 20, 2101-2111.
-
(2001)
Oncogene
, vol.20
, pp. 2101-2111
-
-
Aigner, A.1
Juhl, H.2
Malerczyk, C.3
Tkybusch, A.4
Benz, C.C.5
Czubayko, F.6
-
109
-
-
0034638923
-
Mechanisms of Angiogenesis aand their Use in the Inhibition of Tumor Growth and Metastasis
-
Saaristo, A.; Karpanen, T.; Alitalo, K. Mechanisms of Angiogenesis aand their Use in the Inhibition of Tumor Growth and Metastasis. Oncogene 2000, 19, 6122-6129.
-
(2000)
Oncogene
, vol.19
, pp. 6122-6129
-
-
Saaristo, A.1
Karpanen, T.2
Alitalo, K.3
-
110
-
-
0032752346
-
Expression of VEGF Splice Variants 144/145 and 205/206 in Adult Male Tissues
-
Burchardt, T.; Burchardt, M.; Chen, M. W.; Buttyan, R.; de la Taille, A.; Shabsigh, A.; Shabsigh, R. Expression of VEGF Splice Variants 144/145 and 205/206 in Adult Male Tissues. 1UBMB Life 1999, 48, 405-408.
-
(1999)
1UBMB Life
, vol.48
, pp. 405-408
-
-
Burchardt, T.1
Burchardt, M.2
Chen, M.W.3
Buttyan, R.4
De La Taille, A.5
Shabsigh, A.6
Shabsigh, R.7
-
111
-
-
0031668734
-
Tissue-Specific Expression Pattern of Vascular Endothelial Growth Factor Isoforms in the Malignant Transformation of Lung and Colon
-
[Ill] . Cheung, N.; Wong, M. P.; Yuen, S. T.; Leung, S. Y.; Chung, L. P. Tissue-Specific Expression Pattern of Vascular Endothelial Growth Factor Isoforms in the Malignant Transformation of Lung and Colon. Hum. Pathol. 1998, 29, 910-914.
-
(1998)
Hum. Pathol.
, vol.29
, pp. 910-914
-
-
Cheung, N.1
Wong, M.P.2
Yuen, S.T.3
Leung, S.Y.4
Chung, L.P.5
-
112
-
-
0035060097
-
Specific Reverse Transcription-PCR Quantification of Vascular Endothelial Growth Factor (VEGF) Splice Variants by LightCycler Technology
-
Wellmann, S.; Taube, T.; Paal, K.; Graf, V. E. H.; Geilen, W.; Seifert, G.; Eckert, C.; Henze, G.; Seeger, K. Specific Reverse Transcription-PCR Quantification of Vascular Endothelial Growth Factor (VEGF) Splice Variants by LightCycler Technology. Clin. Chem. 2001, 47, 654-660.
-
(2001)
Clin. Chem.
, vol.47
, pp. 654-660
-
-
Wellmann, S.1
Taube, T.2
Paal, K.3
Graf, V.E.H.4
Geilen, W.5
Seifert, G.6
Eckert, C.7
Henze, G.8
Seeger, K.9
-
113
-
-
0030973506
-
Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice
-
Jeltsch, M.; Kaipainen, A.; Joukov, V.; Meng, X.; Lakso, M.; Rauvala, H.; Swartz, M.; Fukumura, D.; Jain, R. K.; Alitalo, K. Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice. Science 1997,275, 1423-1425.
-
(1997)
Science
, vol.275
, pp. 1423-1425
-
-
Jeltsch, M.1
Kaipainen, A.2
Joukov, V.3
Meng, X.4
Lakso, M.5
Rauvala, H.6
Swartz, M.7
Fukumura, D.8
Jain, R.K.9
Alitalo, K.10
-
114
-
-
0033604614
-
Signaling via Vascular Endothelial Growth Factor Receptors
-
Petrova, T. V.; Makinen, T.; Alitalo, K. Signaling via Vascular Endothelial Growth Factor Receptors. Exp Cell Res. 1999, 253, 117-130.
-
(1999)
Exp Cell Res.
, vol.253
, pp. 117-130
-
-
Petrova, T.V.1
Makinen, T.2
Alitalo, K.3
-
115
-
-
0033730360
-
The Short Form of the Alternatively Spliced flt-4 but not its Ligand Vascular Endothelial Growth Factor C is Related to Lymph Node Metastasis in Human Breast Cancers
-
Gunningham, S. P.; Currie, M. J.; Han, C.; Robinson, B. A.; Scott, P. A.; Harris, A. L.; Fox, S. B. The Short Form of the Alternatively Spliced flt-4 but not its Ligand Vascular Endothelial Growth Factor C is Related to Lymph Node Metastasis in Human Breast Cancers. Clin. Cancer Res. 2000, 6, 4278-4286.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 4278-4286
-
-
Gunningham, S.P.1
Currie, M.J.2
Han, C.3
Robinson, B.A.4
Scott, P.A.5
Harris, A.L.6
Fox, S.B.7
-
116
-
-
0027991841
-
The Predicted Amino Acid Sequence of Human Thioredoxin is Identical to that of the Autocrine Growth Factor Human Adult T-Cell Derived Factor (ADF): Thioredoxin mRNA is Elevated in Some Human Tumors
-
Gasdaska, P. Y.; Oblong, J. E.; Cotgreave, I. A.; Powis, G. The Predicted Amino Acid Sequence of Human Thioredoxin is Identical to that of the Autocrine Growth Factor Human Adult T-Cell Derived Factor (ADF): Thioredoxin mRNA is Elevated in Some Human Tumors. Biochim. Biophys. Ada 1994,1218, 292-296.
-
(1994)
Biochim. Biophys. Ada
, vol.1218
, pp. 292-296
-
-
Gasdaska, P.Y.1
Oblong, J.E.2
Cotgreave, I.A.3
Powis, G.4
-
117
-
-
0030499036
-
Thioredoxin and Thioredoxin Reductase Gene Expression in Human Tumors and Cell Lines, and the Effects of Serum Stimulation and Hypoxia
-
Berggren, M.; Gallegos, A.; Gasdaska, J. R.; Gasdaska, P. Y.; Warneke, J.; Powis, G. Thioredoxin and Thioredoxin Reductase Gene Expression in Human Tumors and Cell Lines, and the Effects of Serum Stimulation and Hypoxia Anticancer Res. 1996,16, 3459-3466.
-
(1996)
Anticancer Res.
, vol.16
, pp. 3459-3466
-
-
Berggren, M.1
Gallegos, A.2
Gasdaska, J.R.3
Gasdaska, P.Y.4
Warneke, J.5
Powis, G.6
-
118
-
-
0035325959
-
Alternative Splicing is Associated with Decreased Expression of the Redox Proto-Oncogene Thioredoxin-1 in Human Cancers
-
Berggren, M. M.; Powis, G. Alternative Splicing is Associated with Decreased Expression of the Redox Proto-Oncogene Thioredoxin-1 in Human Cancers. Arch Biochem. Biophys. 2001, 389, 144-149.
-
(2001)
Arch Biochem. Biophys.
, vol.389
, pp. 144-149
-
-
Berggren, M.M.1
Powis, G.2
-
119
-
-
0035844238
-
Modification of Alternative Splicing of Bcl-x PremRNA in Prostate and Breast Cancer Cells: Analysis of Apoptosis and Cell Death
-
Mercatante, D. R.; Bortner, C. D.; Cidlowski, J. A.; Kole, R. Modification of Alternative Splicing of Bcl-x PremRNA in Prostate and Breast Cancer Cells: Analysis of Apoptosis and Cell Death. J. Biol. Chem. 2001, 276, 16411-16417.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16411-16417
-
-
Mercatante, D.R.1
Bortner, C.D.2
Cidlowski, J.A.3
Kole, R.4
-
120
-
-
0003826861
-
Induction of Endogenous Bcl-xS through the Control of Bcl-x pre-mRNA Splicing by Antisense Oligonucleotides
-
Taylor, J. K.; Zhang, Q. Q.; Wyatt, J. R.; Dean, N. M. Induction of Endogenous Bcl-xS through the Control of Bcl-x pre-mRNA Splicing by Antisense Oligonucleotides. Nat. Biotechnol. 1999, 17, 1097-1100.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 1097-1100
-
-
Taylor, J.K.1
Zhang, Q.Q.2
Wyatt, J.R.3
Dean, N.M.4
-
121
-
-
0033062736
-
Antisense Morpholino Oligonucleotide Analog Induces Missplicing of C-Myc mRNA
-
Giles, R. V.; Spiller, D. G.; Clark, R.E.; Tidd, D. E. Antisense Morpholino Oligonucleotide Analog Induces Missplicing of C-Myc mRNA. Antisense Nucleic Acid DrugDev. 1999,9, 213-220.
-
(1999)
Antisense Nucleic Acid DrugDev.
, vol.9
, pp. 213-220
-
-
Giles, R.V.1
Spiller, D.G.2
Clark, R.E.3
Tidd, D.E.4
-
122
-
-
0033916111
-
Antiproliferative Effects of Steric Blocking Phosphorodiamidate Morpholino Antisense Agents Directed Against C-Myc
-
Hudziak, R. M.; Summerton, J.; Weller, D. D.; Iversen, P. L. Antiproliferative Effects of Steric Blocking Phosphorodiamidate Morpholino Antisense Agents Directed Against C-Myc. Antisense Nucleic Acid Drug Dev.2000,10, 163-176.
-
(2000)
Antisense Nucleic Acid Drug Dev.
, vol.10
, pp. 163-176
-
-
Hudziak, R.M.1
Summerton, J.2
Weller, D.D.3
Iversen, P.L.4
-
123
-
-
0026794668
-
The Mutational Spectrum of Single Base-Pair Substitutions in mRNA Splice Junctions of Human Genes: Causes and Consequences
-
Krawczak, M.; Reiss, J.; Cooper, D. N. The Mutational Spectrum of Single Base-Pair Substitutions in mRNA Splice Junctions of Human Genes: Causes and Consequences. Hum. Genet. 1992, 90, 41-54.
-
(1992)
Hum. Genet.
, vol.90
, pp. 41-54
-
-
Krawczak, M.1
Reiss, J.2
Cooper, D.N.3
-
125
-
-
0002541453
-
Thalassemia Syndromes
-
Huffman, R. et al. ? ed. Churchill Livingston: New York
-
Schwartz, E.; Benz, E. Thalassemia Syndromes. In Hematology: Basic Principles and Practice; Huffman, R. et al. ? ed. Churchill Livingston: New York, 1995, 586-610.
-
(1995)
Hematology: Basic Principles and Practice
, pp. 586-610
-
-
Schwartz, E.1
Benz, E.2
-
126
-
-
0034662881
-
Restoration of Hemoglobin A Synthesis in Erythroid Cells from Peripheral Blood of Thalassemic Patients
-
Lacerra, G.; Sierakowska, H.; Carestia, C.; Fucharoen, S.; Summerton, J.; Weller, D.; Kole, R. Restoration of Hemoglobin A Synthesis in Erythroid Cells From Peripheral Blood of Thalassemic Patients. Proc. Natl. Acad. Sei. U. S. A. 2000, 97, 9591-9596.
-
(2000)
Proc. Natl. Acad. Sei. U. S. A.
, vol.97
, pp. 9591-9596
-
-
Lacerra, G.1
Sierakowska, H.2
Carestia, C.3
Fucharoen, S.4
Summerton, J.5
Weller, D.6
Kole, R.7
-
127
-
-
0033618247
-
Antisense oligonucleotides with Different Backbones. Modification of Splicing Pathways and Efficacy of Uptake
-
Schmajuk, G.; Sierakowska, H.; Kole, R. Antisense oligonucleotides with Different Backbones. Modification of Splicing Pathways and Efficacy of Uptake. J. Biol. Chem. 1999,274, 21783-21789.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21783-21789
-
-
Schmajuk, G.1
Sierakowska, H.2
Kole, R.3
-
128
-
-
0029803547
-
Repair of Thalassemic Human Beta-Globin mRNA in Mammalian Cells by Antisense Oligonucleotides
-
Sierakowska, H.; Sambade, M. J.; Agrawal, S.; Kole, R. Repair of Thalassemic Human Beta-Globin mRNA in Mammalian Cells by Antisense Oligonucleotides. Proc. Natl. Acad. Sei. U. S. A. 1996, 93, 12840-12844.
-
(1996)
Proc. Natl. Acad. Sei. U. S. A.
, vol.93
, pp. 12840-12844
-
-
Sierakowska, H.1
Sambade, M.J.2
Agrawal, S.3
Kole, R.4
-
129
-
-
0032520926
-
A Common Human Beta Globin Splicing Mutation Modeled in Mice
-
Lewis, J.; Yang, B.; Kim, R.; Sierakowska, H.; Kole, R.; Smithies, O.; Maeda, N. A Common Human Beta Globin Splicing Mutation Modeled in Mice. Blood 1998, 91, 2152-2156.
-
(1998)
Blood
, vol.91
, pp. 2152-2156
-
-
Lewis, J.1
Yang, B.2
Kim, R.3
Sierakowska, H.4
Kole, R.5
Smithies, O.6
Maeda, N.7
-
130
-
-
0032485884
-
Up-Regulation of Luciferase Gene Expression with Antisense Oligonucleotides: Implications and Applications in Functional Assay Development
-
Kang, S. H.; Cho, M. J.; Kole, R. Up-Regulation of Luciferase Gene Expression with Antisense Oligonucleotides: Implications and Applications in Functional Assay Development. Biochemistry 1998, 37, 6235-6239.
-
(1998)
Biochemistry
, vol.37
, pp. 6235-6239
-
-
Kang, S.H.1
Cho, M.J.2
Kole, R.3
-
131
-
-
0026699908
-
Screening for Five Mutations Detects 97% of Cystic Fibrosis (CF) Chromosomes and Predicts a Carrier Frequency of 1:29 in the Jewish Ashkenazi Population
-
Abeliovich, D.; Lavon, I. P.; Lerer, L; Cohen, T.; Springer, C.; Avital, A.; Cutting, G. R. Screening for Five Mutations Detects 97% of Cystic Fibrosis (CF) Chromosomes and Predicts a Carrier Frequency of 1:29 in the Jewish Ashkenazi Population. Am. J. Hum. Genet. 1992,51, 951-956.
-
(1992)
Am. J. Hum. Genet.
, vol.51
, pp. 951-956
-
-
Abeliovich, D.1
Lavon, I.P.2
Lerer, L.3
Cohen, T.4
Springer, C.5
Avital, A.6
Cutting, G.R.7
-
132
-
-
0033579478
-
Correction of Aberrant Splicing of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) .Gene by Antisense Oligonucleotides
-
Friedman, K. J.; Kole, J.; Cohn, J. A.; Knowles, M. R.; Silverman, L. M.; Kole, R. Correction of Aberrant Splicing of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) .Gene by Antisense Oligonucleotides. J. Biol. Chem. 1999, 274, 36193-36199.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36193-36199
-
-
Friedman, K.J.1
Kole, J.2
Cohn, J.A.3
Knowles, M.R.4
Silverman, L.M.5
Kole, R.6
-
133
-
-
0026641782
-
The Spectrum of Cystic Fibrosis Mutations
-
Tsui, L. C. The Spectrum of Cystic Fibrosis Mutations. Trends Genet. 1992, 8, 392-398
-
(1992)
Trends Genet.
, vol.8
, pp. 392-398
-
-
Tsui, L.C.1
-
134
-
-
0024466501
-
The Molecular Basis for Duchenne Versus Becker Muscular Dystrophy: Correlation of Severity with Type of Deletion
-
Koenig, M.; Beggs, A. H.; Moyer, M.; Scherpf, S.; Heindrich, K.; Bettecken, T.; Meng, G.; Muller, C. R.; Lindlof, M.; Kaariainen, H.; et al. The Molecular Basis for Duchenne Versus Becker Muscular Dystrophy: Correlation of Severity with Type of Deletion. Am. J.Hum. Genet. 1989, 45, 498-506.
-
(1989)
Am. J.Hum. Genet.
, vol.45
, pp. 498-506
-
-
Koenig, M.1
Beggs, A.H.2
Moyer, M.3
Scherpf, S.4
Heindrich, K.5
Bettecken, T.6
Meng, G.7
Muller, C.R.8
Lindlof, M.9
Kaariainen, H.10
-
135
-
-
0035793047
-
Antisense-Induced Exon Skipping and Synthesis of Dystrophin in the mdx Mouse
-
Mann, C. J.; Honeyman, K.; Cheng, A. J.; Ly, T.; Lloyd, F.; Fletcher, S.; Morgan, J. E.; Partridge, T. A.; Wilton, S. D. Antisense-Induced Exon Skipping and Synthesis of Dystrophin in the mdx Mouse. Proc. Natl. Acad. Sei. U. S. A. 2001, 98, 42-47.
-
(2001)
Proc. Natl. Acad. Sei. U. S. A.
, vol.98
, pp. 42-47
-
-
Mann, C.J.1
Honeyman, K.2
Cheng, A.J.3
Ly, T.4
Lloyd, F.5
Fletcher, S.6
Morgan, J.E.7
Partridge, T.A.8
Wilton, S.D.9
-
136
-
-
0033044501
-
Specific Removal of the Nonsense Mutation from the mdx Dystrophin mRNA Using Antisense Oligonucleotides
-
Wilton, S. D.; Lloyd, F.; Carville, K.; Fletcher, S.; Honeyman, K.; Agrawal, S.; Kole, R. Specific Removal of the Nonsense Mutation from the mdx Dystrophin mRNA Using Antisense Oligonucleotides. Neuromuscul. Disord. 1999, 9, 330-338.
-
(1999)
Neuromuscul. Disord.
, vol.9
, pp. 330-338
-
-
Wilton, S.D.1
Lloyd, F.2
Carville, K.3
Fletcher, S.4
Honeyman, K.5
Agrawal, S.6
Kole, R.7
-
137
-
-
0024387161
-
Cloning and Sequencing of the cDNA Encoding an Isoform of Microtubule-Associated Protein Tau Containing Four Tandem Repeats: Differential Expression of Tau Protein mRNAs in Human Brain
-
Goedert, M.; Spillantini, M. G.; Potier, M. C.; Ulrich, J.; Crowther, R. A. Cloning and Sequencing of the cDNA Encoding an Isoform of Microtubule-Associated Protein Tau Containing Four Tandem Repeats: Differential Expression of Tau Protein mRNAs in Human Brain. EMBO J. 1989, 8. 393-399.
-
(1989)
EMBO J.
, vol.8
, pp. 393-399
-
-
Goedert, M.1
Spillantini, M.G.2
Potier, M.C.3
Ulrich, J.4
Crowther, R.A.5
-
138
-
-
0034971707
-
Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple. Pathogenic Mechanisms
-
Hutton, M. Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple. Pathogenic Mechanisms. Neurology 2001, 56, S21-S25.
-
(2001)
Neurology
, vol.56
-
-
Hutton, M.1
-
140
-
-
0033916608
-
Deletion of Individual Exons and Induction of Soluble Murine Interleukin-5 Receptor-Alpha Chain Expression Through Antisense Oligonucleotide-Mediated Redirection of Pre-mRNA Splicing
-
Karras, J. G.; McKay, R. A.; Dean, N. M.; Monia, B. P. Deletion of Individual Exons and Induction of Soluble Murine Interleukin-5 Receptor-Alpha Chain Expression Through Antisense Oligonucleotide-Mediated Redirection of Pre-mRNA Splicing. Mol Pharmacol. 2000, 58, 380-387.
-
(2000)
Mol Pharmacol.
, vol.58
, pp. 380-387
-
-
Karras, J.G.1
McKay, R.A.2
Dean, N.M.3
Monia, B.P.4
-
141
-
-
2442740920
-
History of Antisense Drug Delivery
-
Crooke, S.; LeBleu, B. Eds.; CRC Press, Inc: Boca Raton
-
Zon, G. History of Antisense Drug Delivery In Antisense Research and Applications; Crooke, S.; LeBleu, B. Eds.; CRC Press, Inc: Boca Raton, 1993, 1-3.
-
(1993)
Antisense Research and Applications
, pp. 1-3
-
-
Zon, G.1
-
142
-
-
0032750621
-
2′-Carbohydrate Modifications in Antisense Oligonucleotide Therapy: Importance of Conformation, Configuration and Conjugation
-
Manoharan, M. 2′-Carbohydrate Modifications in Antisense Oligonucleotide Therapy: Importance of Conformation, Configuration and Conjugation. Biochim Biophys Acta 1999, 1489, 117-130.
-
(1999)
Biochim Biophys Acta
, vol.1489
, pp. 117-130
-
-
Manoharan, M.1
-
143
-
-
0033891369
-
Reduction of Liver Fas Expression by an Antisense Oligonucleotide Protects Mice from Fulminant Hepatitis
-
Zhang, H.; Cook, J.; Nickel, J.; Yu, R.; Stecker, K.; Myers, K.; Dean, N. M. Reduction of Liver Fas Expression by an Antisense Oligonucleotide Protects Mice from Fulminant Hepatitis. Nat. Biotechnol. 2000, 18, 862-867.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 862-867
-
-
Zhang, H.1
Cook, J.2
Nickel, J.3
Yu, R.4
Stecker, K.5
Myers, K.6
Dean, N.M.7
-
144
-
-
0035142861
-
Pharmacokinetics and Pharmacodynamics of an Antisense Phosphorothioate Oligonucleotide Targeting Fas mRNA in Mice
-
Yu, R. Z.; Zhang, H.; Geary, R. S.; Graham, M.; Masarjian, L.; Lemonidis, K.; Crooke, R.; Dean, N. M.; Levin, A. A. Pharmacokinetics and Pharmacodynamics of an Antisense Phosphorothioate Oligonucleotide Targeting Fas mRNA in Mice. J. Pharmacol. Exp. Ther. 2001, 296. 388-395.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, pp. 388-395
-
-
Yu, R.Z.1
Zhang, H.2
Geary, R.S.3
Graham, M.4
Masarjian, L.5
Lemonidis, K.6
Crooke, R.7
Dean, N.M.8
Levin, A.A.9
-
145
-
-
0030463954
-
2′-0-Aminopropyl Ribonucleotides: A Zwitterionic Modification that Enhances the Exonuclease Resistance and Biological Activity of Antisense Oligonucleotides
-
Griffey, R .H.; Monia, B. P.; Cummins, L. L.; Freier, S.; Greig, M. J.; Guinosso, C. J.; Lesnik, E.; Manalili, S. M.; Mohan, V.; Owens, S.; Ross, B. R.; Sasmor, H.; Wancewicz, E.; Weiler, K.; Wheeler, P. D.; Cook, P. D. 2′-0-Aminopropyl Ribonucleotides: a Zwitterionic Modification that Enhances the Exonuclease Resistance and Biological Activity of Antisense Oligonucleotides. J. Med. Chem. 1996,39, 5100-5109.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 5100-5109
-
-
Griffey, R.H.1
Monia, B.P.2
Cummins, L.L.3
Freier, S.4
Greig, M.J.5
Guinosso, C.J.6
Lesnik, E.7
Manalili, S.M.8
Mohan, V.9
Owens, S.10
Ross, B.R.11
Sasmor, H.12
Wancewicz, E.13
Weiler, K.14
Wheeler, P.D.15
Cook, P.D.16
-
146
-
-
0034938693
-
Locked Nucleic Acids: A Promising Molecular Family for Gene-Function Analysis and Antisense Drug Development
-
Orum, H.; Wengel, J. Locked Nucleic Acids: A Promising Molecular Family for Gene-Function Analysis and Antisense Drug Development Curr. Opin. Mol. Ther. 2001, 3, 239-243.
-
(2001)
Curr. Opin. Mol. Ther.
, vol.3
, pp. 239-243
-
-
Orum, H.1
Wengel, J.2
-
147
-
-
0034744290
-
2′-O,4′-C-Methylene Bridged Nucleic Acid (2′,4′-BNA):. Synthesis and Triplex-Forming Properties
-
Obika, S.; Uneda, T.; Sugimoto, T.; Nanbu, D.; Minami, T.; Doi, T.; Imanishi, T. 2′-O,4′-C-Methylene Bridged Nucleic Acid (2′,4′-BNA):. Synthesis and Triplex-Forming Properties. Bioorg. Med. Chem. 2001, 9, 1001-1011.
-
(2001)
Bioorg. Med. Chem.
, vol.9
, pp. 1001-1011
-
-
Obika, S.1
Uneda, T.2
Sugimoto, T.3
Nanbu, D.4
Minami, T.5
Doi, T.6
Imanishi, T.7
-
148
-
-
0035951767
-
2′-O,4′-C-Methylene Bridged Nucleic Acid Modification Promotes Pyrimidine Motif Triplex DNA Formation at Physiological pH
-
Torigoe, H.; Hari, Y.; Sekiguchi, M.; Obika, S.; Imanishi, T. 2′-O,4′-C-Methylene Bridged Nucleic Acid Modification Promotes Pyrimidine Motif Triplex DNA Formation at Physiological pH. J. Biol. Chem. 2001, 270, 2354-2360.
-
(2001)
J. Biol. Chem.
, vol.270
, pp. 2354-2360
-
-
Torigoe, H.1
Hari, Y.2
Sekiguchi, M.3
Obika, S.4
Imanishi, T.5
-
149
-
-
0032699477
-
Morpholino Antisense Oligomers: The Case for an RNase H-Independent Structural Type
-
Summerton, J. Morpholino Antisense Oligomers: the Case for an RNase H-Independent Structural Type. Biochim. Biophys. Acta 1999, 1489, 141-158.
-
(1999)
Biochim. Biophys. Acta
, vol.1489
, pp. 141-158
-
-
Summerton, J.1
-
150
-
-
0033780376
-
Effective Targeted Tene 'Knockdown' in Zebrafish
-
Nasevicius, A.; Ekker, S. C. Effective Targeted Tene 'Knockdown' in Zebrafish. Nat. Genet. 2000, 26, 216-220.
-
(2000)
Nat. Genet.
, vol.26
, pp. 216-220
-
-
Nasevicius, A.1
Ekker, S.C.2
-
151
-
-
0031828692
-
Effect of TNF-Alpha Antisense Oligomers on Cytokine Production by Primary Murine Alveolar Macrophages
-
Taylor, M. F.; Weller, D. D.; Kobzik, L. Effect of TNF-Alpha Antisense Oligomers on Cytokine Production by Primary Murine Alveolar Macrophages. Antisense Nucleic Acid Drug Dev. 1998, 8. 199-205.
-
(1998)
Antisense Nucleic Acid Drug Dev.
, vol.8
, pp. 199-205
-
-
Taylor, M.F.1
Weller, D.D.2
Kobzik, L.3
-
152
-
-
0029337139
-
Synthesis of Novel Phosphoramidite Reagents for the Attachment of Antisense Oligonucleotides to Various Regions of the Benzophenanthridine Ring System
-
Chen, J. K.; Weith, H. L.; Grevval, R. S.; Wang, G.; Cushman, M. Synthesis of Novel Phosphoramidite Reagents for the Attachment of Antisense Oligonucleotides to Various Regions of the Benzophenanthridine Ring System. Bioconjug. Chem. 1995,5, 473-482.
-
(1995)
Bioconjug. Chem.
, vol.5
, pp. 473-482
-
-
Chen, J.K.1
Weith, H.L.2
Grevval, R.S.3
Wang, G.4
Cushman, M.5
-
153
-
-
0028983405
-
Oligonucleotide N3′->P5′ Phosphoramidates
-
Gryaznov, S. M.; Lloyd, D. H.; Chen, J. K.; Schultz, R. G.; DeDionisio, L. A.; Ratmeyer, L.; Wilson, W. D. Oligonucleotide N3′->P5′ Phosphoramidates. Proc. Natl. Acad. Sei. U. S. A. 1995, 92, 5798-5802.
-
(1995)
Proc. Natl. Acad. Sei. U. S. A.
, vol.92
, pp. 5798-5802
-
-
Gryaznov, S.M.1
Lloyd, D.H.2
Chen, J.K.3
Schultz, R.G.4
Dedionisio, L.A.5
Ratmeyer, L.6
Wilson, W.D.7
-
154
-
-
0029664865
-
Oligonucleotide N3′->P5′ phosphoramidates as antisense agents
-
Gryaznov, S.; Skorski, T.; Cucco, C.; Nieborowska-Skorska, M.; Chiu, C. Y.; Lloyd, D.; Chen, J. K.; Koziolkiewicz, M.; Calabretta, B. Oligonucleotide N3′->P5′ phosphoramidates as antisense agents. Nucleic Acids Res. 1996,24, 1508-1514.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 1508-1514
-
-
Gryaznov, S.1
Skorski, T.2
Cucco, C.3
Nieborowska-Skorska, M.4
Chiu, C.Y.5
Lloyd, D.6
Chen, J.K.7
Koziolkiewicz, M.8
Calabretta, B.9
-
155
-
-
0031896629
-
Assessment of High-Affinity Hybridization, RNase H Cleavage, and Covalent Linkage in Translation Arrest by Antisense Oligonucleotides
-
Gee, J. E.; Robbins, I.; van der Laan, A. C.; van Boom, J. H.; Colombier, C.; Leng, M.; Raible, A. M.; Nelson, J. S.; Lebleu, B. Assessment of High-Affinity Hybridization, RNase H Cleavage, and Covalent Linkage in Translation Arrest by Antisense Oligonucleotides. Antisense Nucleic Acid Drug Dev. 1998, 8, 103-311.
-
(1998)
Antisense Nucleic Acid Drug Dev.
, vol.8
, pp. 103-311
-
-
Gee, J.E.1
Robbins, I.2
Van Der Laan, A.C.3
Van Boom, J.H.4
Colombier, C.5
Leng, M.6
Raible, A.M.7
Nelson, J.S.8
Lebleu, B.9
-
156
-
-
0032708143
-
Inhibition of IL-6 in Mice by Anti-NF-KappaB Oligodeoxyribonucleotide N3′->oligodeoxyribon-nucleotide N3′-> P5′ Phosphoramidates
-
Wang, L.; Gryaznov, S.; Nerenberg, M. Inhibition of IL-6 in Mice by Anti-NF-KappaB Oligodeoxyribonucleotide N3′->oligodeoxyribon-nucleotide N3′-> P5′ Phosphoramidates Inflammation 1999, 23, 583-590.
-
(1999)
Inflammation
, vol.23
, pp. 583-590
-
-
Wang, L.1
Gryaznov, S.2
Nerenberg, M.3
-
157
-
-
0034746953
-
Phosphoramidate Oligonucleotides as Potent Antisense Molecules in Cells and in Vivo
-
Faria, M.; Spiller, D. G.; Dubertret, C.; Nelson, J. S.; White, M. R.; Scherman, D.; Helene, C.; Giovannangeli, C. Phosphoramidate Oligonucleotides as Potent Antisense Molecules in Cells and In Vivo. Nat. Biotechnol. 2001, 19, 40-44.
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 40-44
-
-
Faria, M.1
Spiller, D.G.2
Dubertret, C.3
Nelson, J.S.4
White, M.R.5
Scherman, D.6
Helene, C.7
Giovannangeli, C.8
-
159
-
-
0030960680
-
Pharmacokinetic Considerations in the Development of Oligomers as Radiopharmaceuticals
-
Hnatowich, D. J. Pharmacokinetic Considerations in the Development of Oligomers as Radiopharmaceuticals. Q. J. Nucl. Med. 1997, 41, 91-100.
-
(1997)
Q. J. Nucl. Med.
, vol.41
, pp. 91-100
-
-
Hnatowich, D.J.1
-
160
-
-
0028921636
-
Modified Oligonucleotides as Therapeutic and Diagnostic Agents
-
Agrawal, S.; lyer, R. P. Modified Oligonucleotides as Therapeutic and Diagnostic Agents. Curr. Opin. Biotechnol. 1995, 6, 12-19.
-
(1995)
Curr. Opin. Biotechnol.
, vol.6
, pp. 12-19
-
-
Agrawal, S.1
Lyer, R.P.2
-
161
-
-
0034018927
-
Studies on Anti-human Immunodeficiency Virus Oligonucleotides that have Alternating Methylphosphonate/Phosphodiester Linkages
-
Miller, P. S.; Cassidy, R. A.; Hamma, T.; Kondo, N.S. Studies on Anti-human Immunodeficiency Virus Oligonucleotides that have Alternating Methylphosphonate/Phosphodiester Linkages. Pharmacol. Ther. 2000, 85, 159-163.
-
(2000)
Pharmacol. Ther.
, vol.85
, pp. 159-163
-
-
Miller, P.S.1
Cassidy, R.A.2
Hamma, T.3
Kondo, N.S.4
-
162
-
-
0033812002
-
Heterocyclic Modifications of Oligonucleotides and Antisense Technology
-
Herdewijn, P. Heterocyclic Modifications of Oligonucleotides and Antisense Technology. Antisense Nucleic Acid Drug Dev. 2000,10, 297-310.
-
(2000)
Antisense Nucleic Acid Drug Dev.
, vol.10
, pp. 297-310
-
-
Herdewijn, P.1
-
163
-
-
0030057861
-
Effects of Oligonucleotide Length, Mismatches and mRNA Levels on C-5 Propyne-modified Antisense Potency
-
Flanagan, W. M.; Kothavale, A.; Wagner, R. W. Effects of Oligonucleotide Length, Mismatches and mRNA Levels on C-5 Propyne-modified Antisense Potency. Nucleic Acids Res. 1996, 24, 2936-2941.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 2936-2941
-
-
Flanagan, W.M.1
Kothavale, A.2
Wagner, R.W.3
-
164
-
-
0033616610
-
A Cytosine Analog that Confers Enhanced Potency to Antisense Oligonucleotides
-
Flanagan, W. M.; Wolf, J. J.; Olson, P.; Grant, D.; Lin, K. Y.; Wagner, R. W.; Matteucci, M. D. A Cytosine Analog that Confers Enhanced Potency to Antisense Oligonucleotides. Proc. Natl. Acad. Sei. U. S. A. 1999, 96, 3513-3518.
-
(1999)
Proc. Natl. Acad. Sei. U. S. A.
, vol.96
, pp. 3513-3518
-
-
Flanagan, W.M.1
Wolf, J.J.2
Olson, P.3
Grant, D.4
Lin, K.Y.5
Wagner, R.W.6
Matteucci, M.D.7
-
165
-
-
0032528042
-
Biophysical and Antisense Properties of Oligodeoxynucleotides Containing 7-Propynyl-, 7-iodo- And 7-cyano-7-deaza-2-amino-2′-deoxyadenosines
-
Balow, G.; Mohan, V.; Lesnik, E. A.; Johnston, J. F.; Monia, B. P.; Acevedo, O. L. Biophysical and Antisense Properties of Oligodeoxynucleotides Containing 7-Propynyl-, 7-iodo- and 7-cyano-7-deaza-2-amino-2′-deoxyadenosines. Nucleic Acids Res. 1998, 26, 3350-3357.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 3350-3357
-
-
Balow, G.1
Mohan, V.2
Lesnik, E.A.3
Johnston, J.F.4
Monia, B.P.5
Acevedo, O.L.6
-
166
-
-
0034601112
-
Cellular Delivery of Antisense Oligonucleotides
-
Lebedeva, I.; Benimetskaya, L.; Stein, C. A.; Vilenchik, M. Cellular Delivery of Antisense Oligonucleotides. Eur. J. Pharm. Biopharm. 2000, 50, 101-119.
-
(2000)
Eur. J. Pharm. Biopharm.
, vol.50
, pp. 101-119
-
-
Lebedeva, I.1
Benimetskaya, L.2
Stein, C.A.3
Vilenchik, M.4
-
167
-
-
0344562956
-
Novel Cationic Amphiphues as Delivery Agents for Antisense Oligonucleotides
-
DeLong, R. K.; Yoo, H.; Alahari, S. K.; Fisher, M.; Short, S. M.; Kang, S. H.; Kole, R.; Janout, V.; Regan, S. L.; Juliano, R. L. Novel Cationic Amphiphues as Delivery Agents for Antisense Oligonucleotides. Nucleic Acids Res. 1999, 27, 3334-3341.
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 3334-3341
-
-
Delong, R.K.1
Yoo, H.2
Alahari, S.K.3
Fisher, M.4
Short, S.M.5
Kang, S.H.6
Kole, R.7
Janout, V.8
Regan, S.L.9
Juliano, R.L.10
-
168
-
-
0033403876
-
Delivery of Antisense Oligonucleotides and Plasmid DNA with Various Carrier Agents
-
Kang, S. H.; Zirbes, E. L.; Kole, R. Delivery of Antisense Oligonucleotides and Plasmid DNA with Various Carrier Agents. Antisense Nucleic Acid Drug Dev. 1999, 9, 497-505.
-
(1999)
Antisense Nucleic Acid Drug Dev.
, vol.9
, pp. 497-505
-
-
Kang, S.H.1
Zirbes, E.L.2
Kole, R.3
-
169
-
-
0034326297
-
Enhanced Delivery of Antisense Oligonucleotides with Fluorophore-Conjugated PAMAM Dendrimers
-
Yoo, H.; Juliano, R. L. Enhanced Delivery of Antisense Oligonucleotides with Fluorophore-Conjugated PAMAM Dendrimers. Nucleic Acids Res. 2000, 28, 4225-4231.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 4225-4231
-
-
Yoo, H.1
Juliano, R.L.2
-
170
-
-
0342748741
-
Lipid Carrier with a Membrane Active Component and a Small Complex Size are Required for Efficient Cellular Delivery of Anti-sense Phosphorothioate Oligonucleotides
-
Jaaskelainen, I.; Peltola, S.; Honkakoski, P.; Monkkonen, J.; Urtti, A. A Lipid Carrier with a Membrane Active Component and a Small Complex Size are Required for Efficient Cellular Delivery of Anti-sense Phosphorothioate Oligonucleotides. Eur. J. Pharm. Sei. .2000,70, 187-193.
-
(2000)
Eur. J. Pharm. Sei. .
, vol.70
, pp. 187-193
-
-
Jaaskelainen, I.1
Peltola, S.2
Honkakoski, P.3
Monkkonen, J.4
Urtti, A.A.5
-
171
-
-
0034656564
-
Antisense Delivery Using Protamine-Oligonucleotide Particles
-
Junghans, M.; Kreuter, J.; Zimmer, A. Antisense Delivery Using Protamine-Oligonucleotide Particles. Nucleic Acids Res. 2000, 28, E45.
-
(2000)
Nucleic Acids Res.
, vol.28
-
-
Junghans, M.1
Kreuter, J.2
Zimmer, A.3
-
172
-
-
0035937597
-
Nanoparticulate Systems for the Delivery of Antisense Oligonucleotides
-
Lambert, G.; Fattal, E.; Couvreur, P. Nanoparticulate Systems for the Delivery of Antisense Oligonucleotides. Adv. Drug Deliv. Rev. 2001, 47, 99-112.
-
(2001)
Adv. Drug Deliv. Rev.
, vol.47
, pp. 99-112
-
-
Lambert, G.1
Fattal, E.2
Couvreur, P.3
-
173
-
-
0035910877
-
Comparison of Two Methods of Encapsulation of an Oligonucleotide into Poly(D,L-lactic acid) Particles
-
Delie, F.; Berton, M.; Allemann, E.; Gurny, R. Comparison of Two Methods of Encapsulation of an Oligonucleotide into Poly(D,L-lactic acid) Particles. Int. J. Pharm. 2001, 214, 25-30.
-
(2001)
Int. J. Pharm.
, vol.214
, pp. 25-30
-
-
Delie, F.1
Berton, M.2
Allemann, E.3
Gurny, R.4
-
174
-
-
0032404159
-
Cationic Porphyrins: Novel Delivery Vehicles for Antisense Oligodeoxynucleotides
-
Benimetskaya, L.; Takle, G. B.; Vilenchik, M.; Lebedeva, I.; Miller, P.; Stein, C. A. Cationic Porphyrins: Novel Delivery Vehicles for Antisense Oligodeoxynucleotides. Nucleic Acids Res. 1998, 26, 5310-5317.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 5310-5317
-
-
Benimetskaya, L.1
Takle, G.B.2
Vilenchik, M.3
Lebedeva, I.4
Miller, P.5
Stein, C.A.6
-
175
-
-
0035868266
-
Delivery of Oligonucleotides into Mammalian Cells by Anionic Peptides: Comparison between Monomeric and Dimeric Peptides
-
Freuion, L; Roche, A. C.; Monsigny, M.; Mayer, R. Delivery of Oligonucleotides into Mammalian Cells by Anionic Peptides: Comparison between Monomeric and Dimeric Peptides. Biochem. J.2001,354, 671-679.
-
(2001)
Biochem. J.
, vol.354
, pp. 671-679
-
-
Freuion, L.1
Roche, A.C.2
Monsigny, M.3
Mayer, R.4
-
176
-
-
0002034191
-
Cell-Penetrating Peptides
-
Lindgren, M.; Hallbrink, M.; Prochiantz, A.; Langel, U. Cell-Penetrating Peptides. Trends Pharmacol. Sei. 2000,27, 99-103.
-
(2000)
Trends Pharmacol. Sei.
, vol.27
, pp. 99-103
-
-
Lindgren, M.1
Hallbrink, M.2
Prochiantz, A.3
Langel, U.4
-
177
-
-
0031984072
-
Trojan Peptides: The Penetrating System for Intracellular Delivery
-
Derossi, D.; Chassaing, G.; Prochiantz, A. Trojan Peptides: The Penetrating System for Intracellular Delivery. Trends Cell Biol. 1998, 8, 84-87.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 84-87
-
-
Derossi, D.1
Chassaing, G.2
Prochiantz, A.3
-
178
-
-
0034012647
-
Antisense.inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates
-
Astriab-Fisher, A.; Sergueev, D. S.; Fisher, M.; Shaw, B. R.; Juliano, R. L. Antisense.inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates. Biochem. Pharmacol. 2000, 60, 83-90.
-
(2000)
Biochem. Pharmacol.
, vol.60
, pp. 83-90
-
-
Astriab-Fisher, A.1
Sergueev, D.S.2
Fisher, M.3
Shaw, B.R.4
Juliano, R.L.5
-
179
-
-
0034945672
-
Antisense Effects in the Cell Nucleus: Modification of Splicing
-
Kole, R.; Sazani, P. Antisense Effects in the Cell Nucleus: Modification of Splicing. Curr. Opin. Molec. Therapeut. 2001, 3, 229-234.
-
(2001)
Curr. Opin. Molec. Therapeut.
, vol.3
, pp. 229-234
-
-
Kole, R.1
Sazani, P.2
-
180
-
-
0035937124
-
Arginine-Rich Peptides. An Abundant Source of Membrane-Permeable Peptides having Potential as Carriers for Intracellular Protein Delivery
-
Futaki, S.; Suzuki, T.; Ohashi, W.; Yagami, T.; Tanaka, S.; Ueda, K.; Sugiura, Y. Arginine-Rich Peptides. An Abundant Source of Membrane-Permeable Peptides having Potential as Carriers for Intracellular Protein Delivery. J. Biol. Chem. 2001, 270, 5836-5840.
-
(2001)
J. Biol. Chem.
, vol.270
, pp. 5836-5840
-
-
Futaki, S.1
Suzuki, T.2
Ohashi, W.3
Yagami, T.4
Tanaka, S.5
Ueda, K.6
Sugiura, Y.7
-
181
-
-
0034661474
-
Modulation of Plasma Protein Binding and in Vivo Liver Cell Uptake of Phosphorothioate Oligodeoxynucleotides by Cholesterol Conjugation
-
Bijsterbosch, M. K.; Rump, E. T.; De Vrueh, R. L.; Dorland, R.; van Veghel, R.; Tivel, K. L.; Biessen, E. A.; van Berkel, T. J.; Manoharan, M. Modulation of Plasma Protein Binding and In Vivo Liver Cell Uptake of Phosphorothioate Oligodeoxynucleotides by Cholesterol Conjugation. Nucleic Acids Res. 2000, 28, 2717-25.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2717-2725
-
-
Bijsterbosch, M.K.1
Rump, E.T.2
De Vrueh, R.L.3
Dorland, R.4
Van Veghel, R.5
Tivel, K.L.6
Biessen, E.A.7
Van Berkel, T.J.8
Manoharan, M.9
-
182
-
-
0035477551
-
Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs
-
Sazani, P.; Kang, S.H.; Maier, M.A.; Wei, C.; Dillman, J.; Summerton, J.; Manhoran, M. Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs. Nucleic Acids Res. 2001, 29, 3965-74.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 3965-3974
-
-
Sazani, P.1
Kang, S.H.2
Maier, M.A.3
Wei, C.4
Dillman, J.5
Summerton, J.6
Manhoran, M.7
-
183
-
-
0035900725
-
Correction of alternative splicing of tau in frontotemporal dementia and parkinsonsim linked to chromosome 17
-
in press
-
Kalbfuss, B.; Mabon, S.A.; Misteli, T. Correction of alternative splicing of tau in frontotemporal dementia and parkinsonsim linked to chromosome 17. J. Biol. Chem. in press.
-
J. Biol. Chem.
-
-
Kalbfuss, B.1
Mabon, S.A.2
Misteli, T.3
|