Antisense oligonucleotides with different backbones. Modification of splicing pathways and efficacy of uptake

Journal of Biological Chemistry

Volumn 274, Issue 31, 1999, Pages 21783-21789

  Schmajuk, Gabriela ^a   Sierakowska, Halina ^a,b   Kole, Ryszard ^a,c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA;

ARTICLE; CELL MEMBRANE TRANSPORT; CONFORMATIONAL TRANSITION; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN TRANSPORT; RNA SPLICING; TRANSPORT KINETICS;

ALTERNATIVE SPLICING; BASE SEQUENCE; BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE; GLOBINS; HELA CELLS; HUMANS; KINETICS; METHYLATION; MORPHOLINES; OLIGONUCLEOTIDES, ANTISENSE; RNA PRECURSORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033618247     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.31.21783     Document Type: Article

References (57)

1. Stein, C. A., and Krieg, A. M. (eds) (1998) Applied Antisense Oligonucleotide Technology, Wiley-Liss, New York
2. Crooke, S. T. (1998) Biotech. Genet. Eng. Rev. 15, 121-157
3. Crooke, S. T. (1998) Antisense Nucleic Acid Drug Dev. 8, 115-122
4. Gewirtz A. M., Sokol, D. L., and Ratajczak, M. Z. (1998) Blood 92, 712-736
5. Dean, N. M., McKay, R. A., and Holmlund, J. (1998) Antisense Nucleic Acid Drug Dev. 8, 147-151
6. Gewirtz, A. M., and Ratajczak, M. Z. (1998) in Applied Antisense Oligonucleotide Technology (Stein, C. A., and Krieg, A. M., eds) pp. 299-316, Wiley-Liss, New York
7. Agrawal, S. (1998) in Applied Antisense Oligonucleotide Technology (Stein, C. A., and Krieg, A. M., eds) pp. 365-385, Wiley-Liss, New York
8. Martin, R. R. (1998) in Applied Antisense Oligonucleotide Technology (Stein, C. A., and Krieg, A. M., eds) pp. 387-394, Wiley-Liss, New York
9. Crooke, S. T. (1998) Antisense Nucleic Acid Drug Dev. 8, vii-viii
10. Smetsers, T. F., Linders, E. H., van de Locht, L. T., de Witte, T. M., and Mensink, E. J. (1997) Br. J. Haematol. 96, 377-381
11. Benimetskaya, L., Loike, J. D., Khaled, Z., Loike, G., Silverstein, S. C., Cao, L., el Khoury, J., Cai, T. Q., and Stein, C. A. (1997) Nat. Med. 3, 414-420
12. Rockwell, P., O'Connor, W. J., King, K., Goldstein, N. I., Zhang, L. M., and Stein, C. A. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 6523-6528
13. Wang, W., Chen, H. J., Schwartz, A., Cannon, P. J., Stein, C. A., and Rabbani, L. E. (1996) J. Clin. Invest. 98, 443-450
14. Geselowitz, D. A., and Neckers, L. M. (1995) Antisense Res. Dev. 5, 213-217
15. Krieg, A. M., and Stein, C. A. (1995) Antisense Res. Dev. 5, 241
16. Vaerman, J. L., Moureau, P., Deldime, F., Lewalle, P., Lammineur, C., Morschhauser, F., and Martiat, P. (1997) Blood 90, 331-339
17. Branch, A. D. (1998) Antisense Nucleic Acid Drug Dev. 8, 249-254
18. Ho, S. P., Bao, Y., Lesher, T., Malhorta, R., Ma, L. Y., Fluharty, S. J., and Sakai, R. R. (1998) Nat. Biotech. 16, 59-63
19. Milner, N., Mir, K. U., and Southern, E. M. (1997) Nat. Biotech. 15, 537-541
20. Dreyfuss, G., Matunis, M. J., Pinol-Roma, S., and Burd, C. G. (1993) Annu. Rev. Biochem. 62, 289-321
21. Dean, N. M., McKay, R, Condon, T. P., and Bennett, C. F. (1994) J. Biol. Chem. 269, 16416-16424
22. Cioffi, C. L., Garay, M., Johnston, J. F., McGraw, K., Boggs, R. T., Hreniuk, D., and Monia, B. P. (1997) Mol. Pharmacol. 51, 383-389
23. Juliano, R. L., Alahari, S., Yoo, H., Kole, R., and Cho, M. (1999) Pharmaceutical. Res., 16, 494-502
24. Bennett, C. F., Chiang, M.-Y., Chan, H., Shoemaker, J. E. E., and Mirabelli, C. K. (1992) Mol. Pharmacol. 41, 1023-1033
25. Lewis, J. G., Lin, K. Y., Kothavale, A., Flanagan, W. M., Matteucci, M. D., DePrince, R. B., Mook, R. A, Jr., Hendren, R. W., and Wagner, R. W. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 3176-3181
26. Boussif, O., Lezoualc'h, F., Zanta, M. A., Mergny, M. D., Scherman, D., and Demeneix, B., Behr, J. P. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 7297-7301
27. Bielinska, A., Kukowska-Latallo, J. F., Johnson, J., Tomalia, D. A., and Baker, Jr, J. R. (1996) Nucleic Acids Res. 24, 2176-2182
28. Hughes, J. A,. Aronsohn, A. I., Avrutskaya, A. V., and Juliano, R. L. (1996) Pharm. Res. 13, 404-410
29. Leonetti, J. P., Mechti, N., Degols, G., Gagnor, C., and Lebleu, B. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 2702-2706
30. Fisher, T. L., Trehorst, T., Cao, X., and Wagner, R. W. (1993) Nucleic Acids Res. 21, 3857-3865
31. Crooke, S. T., Graham, M. J., Zuckerman, J. E., Brooks, D., Conklin, B. S., Cummins, L. L., Greig, M. J., Guinosso, C. J., Kornbrust, D., Manoharan, M., Sasmor, H. M., Schleich, T., Tivel, K. L., and Griffey, R. H. (1996) J. Pharmacol. Exp. Ther. 277, 923-937
32. Zhang, R., Lu, Z., Zhao, H., Zhang, X., Diasio, R. B., Habus, I., Jiang, Z., Iyer, R. P., Yu, D., and Agrawal, S. (1995) Biochem. Pharmacol. 50, 545-556
33. Nolting, A., DeLong, R. K., Fisher, M. H., Wickstrom, E., Pollack, G. M., Juliano, R. L., and Brouwer, K. L. (1997) Pharm. Res. 14, 516-521
34. Graham, M. J., Crooke, S. T., Monteith, D. K., Cooper, S. R., Lemonidis, K. M., Stecker, K. K., Martin, M. J., and Crooke, R. M. (1998) J. Pharmacol. Exp. Ther. 286, 447-458
35. Dominski, Z., and Kole, R. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 8673-8677
36. Sierakowska, H., Sambade, M. J., Agrawal, S., and Kole, R. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 12840-12844
37. Gorman, L., Suter, D., Emerick, V., Schümperli, D., and Kole, R. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 4929-4934
38. Cheng, T.-C., Orkin, S. H., Antonorakis, S. E., Potter, M. J., Sexton, J. P., Giardina, P. J. V., Li, A., and Kazazian, H. H. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 2821-2826
39. Dobkin, C., and Bank, A. (1985) J. Biol. Chem. 260, 16332-16337
40. Schwartz, E., Benz, E. J., and Forget, B. G. (1995) in Hematology: Basic Principles and Practice (Hoffman, R., Bewz, E. J., Jr., Shattil, S. J., Furie, B., Cohen, H. J., and Silberstein, L. E., eds) pp. 586-610, Churchill Livingstone, New York
41. Tidd, D. M. (1998) in Applied Antisense Oligonucleotide Technology (Stein, C. A., and Krieg, A. M., eds) pp. 161-172 , Wiley-Liss, New York
42. Moore, M. J., Query, C. C., and Sharp, P. A. (1993) in RNA World (Gesteland, R. F., and Atkins, J. F., eds) pp. 303-358, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
43. Sierakowska, H., Montague, M., Agrawal, S., and Kole, R. (1991) Nucleosides Nucleotides 16, 1173-1182
44. Summerton, J., and Weller, D. (1997) Antisense Nucleic Acid Drug Dev. 7, 187-195
45. Hawley-Nelson, P., Ciccarone, V., Gebeyehu, G., Jessee, J., and Felgner, P. L. (1993) Focus 15, 73-79
46. Partridge, M., Vincent, A., Matthews, P., Puma, J., Stein, D., and Summerton, J. (1996) Antisense Nucleic Acid Drug Dev. 6, 169-175
47. Freier, S. M., and Altmann, K. H. (1997) Nucleic Acids Res. 25, 4429-4443
48. Sierakowska, H., Sambade, M. J., Schümperli, D., and Kole, R. (1999) RNA 5, 369-377
49. Lozzio, C. B., and Lozzio, B. B. (1975) Blood 45, 321-334
50. Stein, D., Foster, E., Huang, S. B., Weller, D., and Summerton, J. (1997) Antisense Nucleic Acid Drug Dev. 7, 151-157
51. Hanss, B., Stein, C. A, and Klotman, P. E. (1998) in Applied Antisense Oligonucleotide Technology (Stein, C. A., and Krieg, A. M., eds) pp. 111-128, Wiley-Liss, New York
52. Summerton, J., Stein, D., Huang, S. B., Matthews, P., Weller, D., and Partridge, M. (1997) Antisense Nucleic Acid Drug Dev. 7, 63-70
53. Taylor, M. F., Paulauskia, J. D., Weller, D. W., and Kobzik, L. (1996) J. Biol. Chem. 271, 17445-17452
54. Dominski, Z., and R. Kole. (1992) Mol. Cell. Biol. 12, 2108-2114
55. Berget, S. M. (1995) J. Biol. Chem. 270, 2411-2414
56. Kang, S. H., Cho, M. J., and Kole, R. (1998) Biochemistry 37, 6235-6239
57. Lewis, J., Yang, B., Kim, R., Sierakowska, H., Kole, R., Smithies, O., and Maeda, N. (1998) Blood 91, 2152-2156