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Volumn 19, Issue 1, 2001, Pages 49-56

Herceptin: From the bench to the clinic

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR; GROWTH INHIBITOR; PACLITAXEL; PROTEIN TYROSINE KINASE; TRASTUZUMAB;

EID: 0035083604     PISSN: 07357907     EISSN: None     Source Type: Journal    
DOI: 10.1081/CNV-100000074     Document Type: Review
Times cited : (46)

References (45)
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  • 32
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    • X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling
    • (1993) J. Mol. Biol. , vol.229 , pp. 969-995
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    • Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugs
    • (1998) Oncogene , vol.17 , pp. 2235-2249
    • Pietras, R.J.1    Pegram, M.D.2    Finn, R.S.3
  • 36
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    • Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
    • (1998) Cancer Res. , vol.58 , pp. 2825-2831
    • Baselga, J.1    Norton, L.2    Albanell, J.3
  • 38
    • 0031903646 scopus 로고    scopus 로고
    • Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
    • (1998) J. Clin. Oncol. , vol.16 , pp. 2659-2671
    • Pegram, M.D.1    Lipton, A.2    Hayes, D.F.3
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    • p185cerbB-2 signal enhances cisplatin-induced cytotoxicity in human breast carcinoma cells: Association between an oncogenic receptor tyrosine kinase and drug-induced DNA repair
    • (1994) Cancer Res. , vol.54 , pp. 3758-3765
    • Arteaga, C.L.1    Winnier, A.R.2    Poirier, M.C.3
  • 42
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    • Addition of herceptin (Humanized Anti-HER-2 Antibody) to first line chemotherapy for HER-2 overexpressing metastatic breast cancer (HER-2+/MBC) markedly increases anticancer activity: A randomized, multinational controlled phase III trial
    • (1998) Proc. Am. Soc. Clin. Oncol. , vol.17 , pp. 377
    • Slamon, D.1    Leyland Jones, B.2    Shak, S.3
  • 45
    • 0033590602 scopus 로고    scopus 로고
    • Augmentation of a humanized anti-HER2 mAb 4D5 induced growth inhibition by a human-mouse chimeric anti-EGF receptor mAb C225
    • (1999) Oncogene , vol.18 , pp. 731-738
    • Ye, D.1    Mendelsohn, J.2    Fan, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.