Reduced DNA repair capacity in lung cancer patients

Cancer Research

Volumn 56, Issue 18, 1996, Pages 4103-4107

  Wei, Qingyi ^a   Cheng, Lie ^a   Hong, Waun Ki ^a   Spitz, Margaret R ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; GENE MUTATION; HUMAN; HUMAN CELL; LUNG CANCER; PRIORITY JOURNAL; REPORTER GENE; SMOKING;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; AGE FACTORS; AGED; CELL LINE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CYTOMEGALOVIRUS; DNA DAMAGE; DNA REPAIR; ETHNIC GROUPS; FEMALE; GENES, REPORTER; HUMANS; LUNG NEOPLASMS; LYMPHOCYTES; MALE; MIDDLE AGED; MUTAGENS; REFERENCE VALUES; RISK FACTORS; SMOKING;

EID: 0029832418     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Parker, S. L., Tong, T., Bolden, S., and Wingo, P. A. Cancer Statistics, 1996. Atlanta, GA, American Cancer Society Inc., 1996.
2. Davila, D G , and Williams, D. E. The etiology of lung cancer. Mayo Clin. Proc., 68. 170-182, 1993.
3. Knudson, A G., Jr. Overview: genes that predispose to cancer. Mutat. Res., 247: 185-190, 1991
4. Mattson, M. E., Pollack, E. S., and Cullen, J. W What are the odds that smoking will kill you? Am. J. Public Health, 77: 425-431, 1987.
5. Caporaso, N., Landi, M. T., and Vineis, P. Relevance of metabolic polymorphisms to human carcinogenesis: evaluation of epidemiologic evidence. Pharmacogenetics, 1 4-19, 1991.
6. Phillips, D. H. Fifty years of B(a)P. Nature (Lond.), 303: 468-472, 1983.
7. Gelboin, H. V. Benzo[a]pyrene metabolism, activation, and carcinogenesis: role and regulation of mixed function oxidases and related enzymes. Physiol. Rev., 60: 1107-1166, 1980.
8. MacLeod, M. C., and Tang, M. S. Interaction of benzo[a]pyrene-diol-epoxides with linear and supercoiled DNA Cancer Res., 45: 51-56, 1985.
9. Cosman, M. de los Santos, C , Fiala, R., Hingerty, B. E., Sigh, S. B., Ibanez, V , Margulis, L. A., Live, D., Geacintov, N. E , Broyde, S., and Petel, D. J. Solution conformation of the major adducts between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA Proc. Natl. Acad. Sci. USA, 89: 1914-1918, 1992.
10. Everson, R. B., Randerath, E., Santella, R. M., Cefalo, R C., Avitts, T. A , and Randerath, K. Detection of smoking-related covalent DNA adducts in human placenta Science (Washington DC), 231. 54-57, 1986.
11. Perera, F. P , Santella, R. M., Brenner, D., Poirier, M. C , Munshi, A. A., Fischman, H. K., and Van Ryzin, J. V. DNA adducts, protein adducts, and sister chromatid exchange in cigarette smokers and nonsmokers. J Natl. Cancer Inst., 79: 449-456, 1987.
12. van Schooten, F. J., van Leeuwen, F. E., Hillebrand, M J. X., de Rijke, M. E., Hart, A. A. M., van Veen, H G., Osterink, S., and Kriek, E. Determination of benzo-[a]pyrene diol epoxide-DNA adducts in white blood cell DNA from coke-oven workers: the impact of smoke. J Natl. Cancer Inst., 82: 927-933, 1990.
13. 32P-postlabelling and aryl hydrocarbon hydroxylase activity in lung parenchyma of smokers and ex-smokers. Carcinogenesis (Lond.), 12: 1301-1305, 1991.
14. Izzotti, A., Rossi, G. A., Bagnasco, M., and Flora, S. D. Benzo[a]pyrene diol epoxide-DNA adducts in alveolar macrophages. Carcinogenesis (Lond.), 12 1281-1285, 1991.
15. Wei, S., Chang, R., Wong, C. Bhachech, N , Cui, X X , Hennig, E., Yagi, H., Saver, J M., Jerina, D. M., Preston, B. D., and Conney, A. H. Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene. Proc. Natl. Acad. Sci. USA, 88: 11227-11230, 1991.
16. Sancer, A. DNA repair in humans. Annu. Rev. Genet., 29: 69-105, 1995.
17. Sellers, T. A., Potter, J. D , Bailey-Wilson, J. E., Rich, S S., Rothschild, H., and Elston, R. C. Lung cancer detection and prevention: evidence for an interaction between smoking and genetic predisposition Cancer Res., 52: 2694s-2697s, 1992.
18. Tang, M S , Pierce, J. R., Doisy, R. P., Nazimiec, M E., and MacLeod, M. C Differences and similarities in the repair of two benzo[a]pyrene diol epoxide isomers induced DNA adducts by uvrA, uvrB, and uvrC gene products. Biochemistry, 31: 8429-8436, 1992.
19. Chen, R. H., Maher, V. M., Brouwer, J., van de Putte, P., and McCormick, J. J Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in HPRT gene of diploid human fibroblasts Proc. Natl. Acad Sci. USA, 89: 5413-5417, 1992.
20. Chiba, I., Takahashi, T , Nau, M. M., Amico, D., Curiel, D. T., Mitsudomi, T , Buchhagen, D. L., Carbone, D., Piantadosi, S., Koga, H., Reissman, P T , Slamon, D. J., Holmes, C E , and Minna, J. D. Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Oncogene, 5: 1603-1616, 1990.
21. Susuki, H. Takahashi, T , Kuroiki, T. Suyama, M., Ariyoshi, Y., and Takahashi, T p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking. Cancer Res., 52: 734-736, 1992.
22. Athas, A. F., Hedayati, M., Matanoski, G. M., Farmer, E. R., and Grossman, L Development and field-test validation of an assay for DNA repair in circulating human lymphocytes Cancer Res., 51: 5786-5793, 1991
23. Wei, Q., Matanoski, G. M., Farmer, E. R , Hedayati, M , and Grossman, L. DNA repair and aging in basal cell carcinoma: a molecular epidemiologic study. Proc Natl. Acad. Sci. USA, 90: 1614-1618, 1993.
24. Spitz, M. R., Hsu, T. C , Wu, X., Fueger, J. J , Amos, C I., and Roth, J. A. Mutagen sensitivity as a biological marker of lung cancer risk in African Americans. Cancer Epidemiol. Biomarkers Prev., 4: 99-103, 1995.
25. Strom, S. S., Wu, X., Sigurson, A. J., Hsu, T. C., Fueger, J. J., Lopez, J., Tee, T G , and Spitz, M. R. Lung cancer smoking pattern and mutagen sensitivity in Mexican Americans Monogr. J. Nad. Cancer Inst., 18: 29-33, 1995.
26. McCuchan, J. H., and Pagano, J. S. Enhancement of the infectivity of simian virus 40 deoxynbonucleic acid with diethylaminoethyl-dextran. J. Natl. Cancer Inst., 41: 351-356, 1968.
27. Wiencke, J. K., Kelsey, K T., Varkonyi, A., Semey, K., Wain, J. C., Mark, E., and Christiani, D C. Correlation of DNA adducts in blood mononuclear cells with tobacco carcinogen-induced damage in human lung Cancer Res., 55, 4910-4914, 1995.
28. Hall, J., English, D. R., Artuso, M., Armstrong, B. K , and Winter, M. DNA repair capacity as a risk factor for non-melanocytic skin cancer - a molecular epidemiological study. Int. J. Cancer, 58: 179-184, 1994.
29. Yang, L L., Maher, V M , and McCormick, J. J. Relationship between excision repair and benzo[a]pyrene in human cells. Mutat Res., 94: 435-437, 1982.
30. Cheng, L , Bucana, C. D., and Wei, Q. Fluorescence in situ hybridization method for measuring transfection efficiency. Biotechniques, in press, 1996.
31. O'Brien, S. N., Larcom, L. L., and Baxlet, E. G. Correlates of plasma cortisol and DNA repair in human peripheral lymphocytes: suppression of repair in women taking estrogen. Horm. Res. (Basel), 39: 241-246, 1993.