Alternative splicing, but not allelic loss, of the FHIT gene increases with development of lung cancer

International Journal of Oncology

Volumn 15, Issue 1, 1999, Pages 81-88

  Ishioka, Shinichi ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Alternative splicing; FHIT gene; Lung cancer; Telomerase activity; Telomere length

Indexed keywords

ACID ANHYDRIDE HYDROLASE; FRAGILE HISTIDINE TRIAD PROTEIN; MESSENGER RNA; PROTEIN; RNA; TELOMERASE; TUMOR PROTEIN;

ALLELE; ARTICLE; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; HETEROZYGOSITY LOSS; HUMAN; HUMAN CHROMOSOME; LUNG NON SMALL CELL CANCER; LUNG TUMOR; METABOLISM; PATHOLOGY; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SMALL CELL CARCINOMA; TELOMERE; TUMOR SUPPRESSOR GENE; ULTRASTRUCTURE;

ACID ANHYDRIDE HYDROLASES; ALLELES; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SMALL CELL; CHROMOSOMES, HUMAN; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; LOSS OF HETEROZYGOSITY; LUNG NEOPLASMS; NEOPLASM PROTEINS; PROTEIN BIOSYNTHESIS; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA SPLICING; RNA, MESSENGER; RNA, NEOPLASM; TELOMERASE; TELOMERE;

EID: 0033159536     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (3)

1. Naylor SL, Johnson BE, Minna JD and Sakaguchi AY: Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer. Nature 329: 451-454, 1987.
2. Yokota J, Wada M, Shimosato Y, Terada M and Sugimura T: Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung. Proc Natl Acad Sci USA 84: 9252-9256, 1987.
3. Rabbitts P, Douglas J, Daly M, Sundaresan V, Fox B, Haselton P, Wells F, Albertson D, Waters J and Bergh J: Frequency and extent of allelic loss in the short arm of chromosome 3 in non-small-cell lung cancer. Genes Chromosomes Cancer 1: 95-105, 1989.