Up-regulation of ICH-1(L) protein by thromboxane A2 antagonists enhances cisplatin-induced apoptosis in non-small-cell lung-cancer cell lines

Journal of Cancer Research and Clinical Oncology

Volumn 125, Issue 7, 1999, Pages 389-394

  Fujimura, Masaki ^a   Kasahara, Kazuo ^a   Shirasaki, Hiroki ^a   Heki, Utako ^a   Iwasa, Keiichi ^a   Ueda, Akiko ^a   Matsuda, Tamotsu ^a  

^a KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Cisplatin; ICH 1(L); Non small cell lung cancer; Thromboxane A2

Indexed keywords

5 [6 [3 (N 4 BROMOBENZENESULFONYLAMINOMETHYL)BICYCLO[2,2,1]HEPTANE 2 YL]HEX 5 ENOIC ACID]; CASPASE; CISPLATIN; DOMITROBAN; ONO NT 126; PROTEIN ICH 1L; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

APOPTOSIS; BICYCLO COMPOUNDS; BLOTTING, WESTERN; CARCINOMA, NON-SMALL-CELL LUNG; CASPASE 2; CASPASES; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FATTY ACIDS, MONOUNSATURATED; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; PROSTAGLANDIN ANTAGONISTS; THROMBOXANE A2; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0033024272     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004320050291     Document Type: Article

References (29)

1. Aebi S, Kurdi-Haidar B, Gordon R, Cenni B, Zheng H, Fink D, Christen RD, Boland CR, Koi M, Fishel R, Howell SB (1996) Loss of DNA mismatch repair in acquired resistance to cisplatin. Cancer Res 56:3087-3090
2. An B, Dou QP (1996) Cleavage of retinoblastoma protein during apoptosis: an interleukin 1β converting enzyme-like protease as candidate. Cancer Res 56:438-442
3. Andrews PA, Howell SB (1990) Cellular pharmacology of cisplatin: perspective on mechanisms of acquired resistance. Cancer Cells 2:35-43
4. Andrews PA, Velury S, Mann SC, Howell SB (1988) cis-Diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells. Cancer Res 48:68-73
5. 2 attenuates sensitivity to cis-diamminedichloroplatinum(II) in non-small cell lung cancer cell lines in vitro. Proc Am Assoc Cancer Res 36:371
6. Benjamin CW, Hiebsch RR, Jones DA (1998) Caspase activation in MCF7 cells responding to etoposide treatment. Mol Pharmacol 53:446-450
7. Cohen GM (1997) Caspases: the executioners of apoptosis. Biochem J 326:1-16
8. Datte R, Banach D, Kojima H, Talanian RV, Alnemri ES, Wong WW, Kufe DW (1996) Activation of the CPP32 protease in apoptosis induced by 1-β-D-arabinofuranosylcytosine and other DNA-damaging agents. Blood 88:1936-1943
9. Del Bino G, Skierski JS, Darzynkiewicz Z (1991) The concentration-dependent diversity of effects of DNA topoisomerase I and II inhibitors on the cell cycle of HL-60 cells. Exp Cell Res 195:485-491
10. 2 receptor ligand (S-145) in platelets and vascular and airway smooth muscle. J Pharmacol Exp Ther 262:784-791
11. Fujiwara Y, Sugimoto Y, Kasahara K, Bungo M, Yamakido M, Tew KD, Saijo N (1990) Determinants of drug response in a cisplatin-resistant human lung cancer cell line. Jpn J Cancer Res 81:527-535
12. Hiwasa T, Tokita H, Sakiyama S, Nakagaware A (1998) Enhancement of chemosensitivity toward anticancer drugs by high expression of caspase-1 in NIH 3T3 cells. Anti-cancer Drugs 9:82-81
13. 2 mediates cisplatin-induced apoptosis of renal tubule cells. Biochem Mol Biol Int 42:113-121
14. Kasahara K, Fujiwara Y, Nishio K, Ohmori T, Sugimoto Y, Komiya K, Matsuda T, Saijo N (1991) Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin. Cancer Res 51:3237-3242
15. 2 receptor antagonists in non-small cell lung cancer cell lines. Br J Cancer 74:1553-1558
16. Kondo S, Barna BP, Morimura T, Takeuchi J, Yuan J, Akbasak A, Barnett GH (1995) Interleukin-1β-converting enzyme mediates cisplatin-induced apoptosis in malignant glioma cells. Cancer Res 55:6166-6171
17. Kumar S, Kinoshita M, Noda M, Copeland NG, Jenkins NA (1994) Induction of apoptosis by the mouse nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian 1L-1β-converting enzyme. Gene Dev 8:1613-1626
18. Li H, Bergeron L, Cryns V, Paternack MS, Zhu H, Shi L, Greenberg A, Yuan J (1997) Activation of caspase-2 in apoptosis. J Biol Chem 34:21010-21017
19. Loether PJ, Einhorn LH (1984) Cisplatin. Ann Intern Med 100:704-713
20. Nagane M, Levitzke A, Grazit A, Cavenee WK, Huang HS (1997) Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases. Proc Natl Acad Sci USA 95:5724-5729
21. 2: a receptor-mediated event. Adv Prostaglandin Thromboxane Leukotriene Res 21:925-928
22. 2 in plasma samples from patients with benign and malignant tumors of the breast. Prostaglandins 29:513-528
23. 2 formation. A Engl J Med 319:689-698
24. Perego P, Giarola M, Righetti SC, Supino R, Caserini C, Delia D, Pierotti MA, Miyashita T, Reed JC, Zunino F (1996) Association between cisplatin resistance and mutation of p53 gene and reduced Bax expression in ovarian carcinoma cell systems. Cancer Res 56:556-562
25. Sumantran VN, Elaovage MW, Nunez G, Clarke MF, Wicha MS (1995) Overexpression of Bcl-Xs sensitizes MCF-7 cells to chemotherapy-induced apoptosis. Cancer Res 55:2507-2510
26. Suzuki A, Kawabata T, Kato M (1998) Necessity of interleukin 1β converting enzyme cascade in taxotere-induced death signaling. Eur J Pharmacol 343:87-92
27. Ueda N, Shah SV (1994) Apoptosis. J Lab Clin Med 125:169-177
28. 2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis. J Exp Med 178: 1825-1830
29. Wang L, Miura M, Bergeron L, Zhi H, Yuan J (1994) ICH-1, and ICE/Ced-3 related gene, encodes both positive and negative regulators of programmed cell death. Cell 78:739-750