Arginine methylation of STAT1 modulates IFNα/β-induced transcription

Cell

Volumn 104, Issue 5, 2001, Pages 731-741

  Mowen, Kerri A ^a   Tang, Jie ^b   Zhu, Wei ^a   Schurter, Brandon T ^a   Shuai, Ke ^b   Herschman, Harvey R ^b   David, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' METHYLTHIOADENOSINE; ALPHA INTERFERON; ARGININE; BETA INTERFERON; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN INHIBITOR; STAT1 PROTEIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN METHYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REACTION ANALYSIS; TRANSCRIPTION REGULATION;

EID: 0035831040     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00269-0     Document Type: Article

References (47)

1. A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor
2. Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains
3. Direct evidence for methylation of arginine residues in high molecular weight forms of basic fibroblast growth factor
4. Methylthioadenosine (MeSAdo) phosphorylase deficiency in malignancy
5. Regulation of transcription by a protein methyltransferase
6. Specific inhibition of Stat3 signal transduction by PIAS3
7. Nerve growth factor-specific regulation of protein methylation during neuronal differentiation of PC12 cells
8. Protein methylation
9. Requirement for MAP kinase (ERK2) activity in interferonα/β-stimulated gene expression through Stat proteins
10. Differential regulation of the IFNα/β-stimulated Jak/Stat pathway by the SH2-domain containing tyrosine phosphatase SHPTP1
11. Activation of protein kinase A inhibits IFN induction of the Jak/Stat pathway in U266 cells
12. The SH2-domain containing tyrosine phosphatase PTP1D is required for IFNα/β-induced gene expression
13. Deficiency of 5′-deoxy-5′-methylthioadenosine phosphorylase activity in malignancy. Absence of the protein in human enzyme-deficient cell lines
14. Enzyme deficiency and tumor suppressor genes: Absence of 5′-deoxy-5′-methylthioadenosine phosphorylase in human tumors
15. 5′-deoxy-5′-methylthioadenosine phosphorylase and p16INK4 deficiency in multiple tumor cell lines
16. Methylthioadenosine phosphorylase deficiency in human leukemias and solid tumors
17. RNA and protein interactions modulated by protein arginine methylation
18. Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway
19. Selective killing of human malignant cell lines deficient in methylthioadenosine phosphorylase, a purine metabolic enzyme
20. Transcription factor-specific requirements for coactivators and their acetyltransferase functions
21. Lipopolysaccharide-induced NF-kappa B activation in mouse 70Z/3 pre-B lymphocytes is inhibited by mevinolin and 5′-methylthioadenosine: Roles of protein isoprenylation and carboxyl methylation reactions
22. Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction
23. The mammalian immediate-early TIS21 protein and the leukemia-associated BTG1 protein interact with a protein-arginine N-methyltransferase
24. Inhibition of Stat1-mediated gene activation by PIAS1
25. Inhibition of the tyrosine kinase activity of the fibroblast growth factor receptor by the methyltransferase inhibitor 5′-methylthioadenosine
26. The protein tyrosine kinase JAK1 complements defects in the interferon-α/β and -γ signal transduction
27. Peptides with sequences similar to glycine, arginine-rich motifs in proteins interacting with RNA are efficiently recognized by methyltransferase(s) modifying arginine in numerous proteins
28. The RGG domain in hnRNP A2 affects subcellular localization
29. Absence of methylthioadenosine phosphorylase in human gliomas
30. Methylthioadenosine phosphorylase deficiency in human non-small cell lung cancers
31. Genomic cloning of methylthioadenosine phosphorylase: A purine metabolic enzyme deficient in multiple different cancers
32. Methylation of high molecular weight fibroblast growth factor-2 determines post-translational increases in molecular weight and affects its intracellular distribution
33. The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity
34. Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
35. Arginine methylation facilitates the nuclear export of hnRNP proteins
36. A single phosphotyrosine residue of Stat91 required for gene activation by interferonγ
37. Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1
38. Methylthioadenosine phosphorylase in human breast cancer
39. Amino-terminal signal transducer and activator of transcription (STAT) domains regulate nuclear translocation and STAT deactivation
40. PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation
41. Methylthioadenosine phosphorylase deficiency in acute leukemia: Pathologic, cytogenetic, and clinical features
42. A protein tyrosine kinase in the interferon α/β signaling pathway
43. Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-γ signal transduction pathway
44. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
45. Trends in the biochemical pharmacology of 5′-deoxy-5′-methylthioadenosine
46. Interferon γ rapidly induces in human monocytes a DNA-binding factor that recognizes the γ response region within the promoter of the gene for the high-affinity Fcγ receptor
47. Codeletion of the genes for p16INK4, methylthioadenosine phosphorylase, interferon-alpha1, interferon-beta1, and other 9p21 markers in human malignant cell lines