SOCS3 is essential in the regulation of fetal liver erythropoiesis

Cell

Volumn 98, Issue 5, 1999, Pages 617-627

  Marine, Jean Christophe ^a   McKay, Catriona ^a   Wang, Demin ^a   Topham, David J ^a   Parganas, Evan ^a   Nakajima, Hideaki ^a   Pendeville, Hélène ^a   Yasukawa, Hideo ^c   Sasaki, Atsuo ^c   Yoshimura, Akihiko ^c   Ihle, James N ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^c KURUME UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; EMBRYO DEVELOPMENT; ERYTHROCYTOSIS; ERYTHROPOIESIS; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; STEM CELL;

ANIMALIA; JANUS; MAMMALIA; RODENTIA;

EID: 0033520389     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80049-5     Document Type: Article

References (41)

1. Adams, I.E., Hansen, J.A., Starr, R., Nicola, N.A., Hilton, D.J., and Billestrup, N. (1998). Growth hormone preferentially induces the rapid, transient expression of SOCS3, a novel inhibitor of cytokine receptor signaling. J. Biol. Chem. 273, 1285-1287.
2. Andrews, N.C., and Orkin, S.H. (1994). Transcriptional control of erythropoiesis. Curr. Opin. Hematol. 1, 119-124.
3. Angerer, L.M., and Angerer, R.C. (1991). Localization of mRNAs by in situ hybridization. Methods Cell Biol. 35, 37-71.
4. Auernhammer, C.J., and Melmed, S. (1999). lnterleukin-11 stimulates proopiomelanocortin gene expression and adrenocorticotropin secretion in corticotroph cells: evidence for a redundant cytokine network in the hypothalamo-pituitary-adrenal axis. Endocrinology 140, 1559-1566.
5. Auernhammer, C.J., Chesnokova, V., Bousquet, C., and Melmed, S. (1998). Pituitary corticotroph SOCS3: novel intracellular regulation of leukemia-inhibitory factor-mediated proopiomelanocortin gene expression and adrenocorticotropin secretion. Mol. Endocrinol. 12, 954-961.
6. Auernhammer, C.J., Bousquet, C., and Melmed, S. (1999). Autoregulation of pituitary corticotroph SOCS3 expression: characterization of the murine SOCS3 promoter. Proc. Natl. Acad. Sei. USA 96, 6964-6969.
7. Bentley, D., Selfridge, J., Millar, U.K., Samuel, K., Hole, N., Ansell, J.D., and Melton, D.W. (1996). DMA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viability. Nat. Genet. 13, 489-491.
8. Bjorbaek, C., Elmquist, U.K., Frantz, J.D., Shoelson, S.E., and Flier, U.S. (1998). Identification of SOCS3 as a potential mediator of central leptin resistance. Mol. Cell 1, 619-625.
9. Bjorbaek, C., Elmquist, U.K., EI-Haschimi, K., Kelly, J., Ahima, R.S., Hileman, S., and Flier, U.S. (1999). Activation of SOCS3 messenger ribonucleic acid in the hypothalamus by ciliary neurotrophic factor. Endocrinology 140, 2035-2043.
10. Cohney, S.u., Sanden, D., Cacalona, N.A., Yoshimura, A., Mui, A., Migone, T.S., and Johnston, U.A. (1999). SOCS3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation. Mol. Cell. Biol. 19, 4980-4988.
11. Domen, J., Gandy, K. L, and Weissman, I.L. (1998). Systemic over expression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood 91, 2272-2282.
12. Galli, S.u., Zsebo, K.M., and Geissler, E.N. (1994). The kit ligand, stem cell factor. Adv. Immunol. 55, 1-96.
13. Hakem, R., Hakem, A., Duncan, G.S., Henderson, J.T., Woo, M., Soengas, M .S., Ella, A., Pompa, J.L., Kagi, D., Khoo, W., et al. (1998). Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell 94, 339-352.
14. Ikuta, K., Kina, T., MacNeil, I., Uchida, N., Peault, B., Chien, Y.-H., and Weissman, I.L. (1990). A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells. Cell 62, 863-874.
15. Ito, S., Ansari, P., Sakatsume, M., Dickensheets, H., Vazquez, N., Donnelly, R.P., Larner, A.C., and Finbloom, D.S. (1999). Interleukin10 inhibits expression of both Interferon alpha- and Interferon gamma-induced genes by suppressing tyrosine phosphorylation of STAT1. Blood 93, 1456-1463.
16. Kamura, T., Sato, S., Haque, D., Liu, L, Kaelin, W.G.J., Conaway, R.C., and Conaway, J.W. (1998). The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families. Genes Dev. 12, 3872-3881.
17. Klingmuller, U., Lorenz, U., Cantley, L.C., Neel, B.G., and Lodish, H.F. (1995). Specific recruitment of the hematopoietic protein tyrosine phosphatase SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell 80, 729-738.
18. Kondo, M., Akashi, K., Domen, J., Sugamura, K., and Weissman, I.L. (1997). Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common gamma chain-deficient mice. Immunity 7, 155-162.
19. Marine, J.-C., Topham, D.J., McKay, C., Wang, D., Parganas, E., Stravopodis, D., Yoshimura, A., and Ihle, J.N. (1999). SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality. Cell 98, this issue, 609-616.
20. Matsumoto, A., Masuhara, M., Mitsui, K., Yokouchi, M., Ohtsubo, M., Misawa, H., Miyajima, A., and Yoshimura, A. (1997). CIS, a cytokine inducibleSH2 protein, is a target of the jak-stat5 pathway and modulates stat5 activation. Blood 89, 3148-3154.
21. Motoyama, N., Wang, F., Roth, K.A., Sawa, H., Nakayama, K., Nakayama, K., Negishi, I., Senju, S., Zhang, Q., Fujii, S., and Loh, D.Y. (1995). Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science 267, 1506-1510.
22. Naka, T., Matsumoto, T., Narazaki, M., Fujimoto, M., Morita, Y., Ohsawa, Y., Saito, H., Nagasawa, T., Uchiyama, Y., and Kishimoto, T. (1998). Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice. Proc. Natl. Acad. Sei. USA 95, 15577-15582.
23. Neubauer, H., Cumano, A., Muller, M., Wu, H., Huffstadt, U., and Pfeffer, K. (1998). Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell 93, 397-409.
24. Orkin, S.H. (1998). Embryonic stem cells and transgenic mice in the study of hematopoiesis. Int. J. Dev. Biol. 42, 927-934.
25. Orkin, S.H., and Zon, L.I. (1997). Genetics of erythropoiesis: induced mutations in mice and zebrafish. Annu. Rev. Genet. 31, 33-60.
26. Parganas, E., Wang, D., Stravopodis, D.,Topham, D.U., Marine, J.-C., Teglund, S., Vanin, E.F., Bodner, S., Colamonici, O.R., van Deursen, J.M., Grosveld, G., and Ihle, J.N. (1998). Jak2 is essential for signaling through a variety of cytokine receptors. Cell 93, 385-395.
27. Sasaki, A., Yasukawa, H., Suzuki, A., Kamizono, S., Syoda,T., Kinjyo, I., Sasaki, M., Johnston, J.A., and Yoshimura, A. (1999). Cytokineinducible SH2 protein-3 (CIS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain. Genes Cells, in press.
28. L induction. Cell 98, 181-191.
29. Song, M .M., and Shuai, K. (1998). The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibits interfei onmediated antiviral and antiproliferative activities. J. Biol. Chem. 273, 35056-35062.
30. Starr, R., Willson, T.A., Viney, E.M., Murray, L.J., Rayner, J.R., Jenkins, B.J., Gonda, T.J., Alexander, W.S., Metcalf, D., Nicola, N.A., and Hilton, D.U. (1997). A family of cytokine-inducible inhibitors of signaling. Nature 387, 917-921.
31. Starr, R., Metcalf, D., Elefanty, A.G., Brysha, M., Willson, T.A., Nicola, N.A., Hilton, D.U., and Alexander, W.S. (1998). Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1. Proc. Natl Acad. Sei. USA 95, 14395-14399.
32. Teglund, S., McKay, C., Schuetz, E., van Deursen, J., Stravopodis, D., Wang, D., Brown, M., Bodner, S., Grosveld, G., and Ihle, J.N. (1998). StatSa and StatSb proteins have essential and non-essential, or redundant, roles in cytokine responses. Cell 93, 841-850.
33. van Deursen, J., Lovell-Badge, R., Oerlemans, F., Schepens, J., and Wieringa, B.(1991). Modulation of gene activity by consecutive gene targeting of one creatine kinase M allele in mouse embryonic stem cells. Nucleic Acids Res. 19, 2637-2643.
34. van Deursen, J., Heerschap, A., Oerlemans, F., Ruitenbeek, W., Jap, P., ter Laak, H., and Wieringa, B. (1993). Skeletal muscles of mice deficient in muscle creatine kinase lack burst activity. Cell 74, 621-631.
35. Varfolomeev, E.E., Schuchmann, M., Luria, V., Chiannilkulchai, N., Beckmann, J.S., Mett, I.L., Rebrikov, D., Brodianski, V.M., Kemper, O.C., Kollet, O., et al. (1998). Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas Apo1, and DR3 and is lethal prenatally. Immunity 9, 267-276.
36. Wu, H., Klingmuller, U., Besmer, P., and Lodish, H.F. (1995a). Interaction of the erythropoietin and stem-cell-factor receptors. Nature 377, 242-246.
37. Wu, H., Liu, X., Jaenisch, R., and Lodish, H.F. (1995b). Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell 83, 59-67.
38. Yasukawa, H., Misawa, H., Sakamoto, H., Masuhara, M., Sasaki, A, Wakioka, T., Ohtsuka, S., Imaizumi, T., Matsuda, T., Ihle, J.N., and Yoshimura, A. (1999). The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. EM BO J. 18, 1309-1320.
39. Yeh, W.-C., de la Pompa, J.L., McCurrach, M.E., Shu, H., Elia, A.J., Shahinian, A., Ng, M., Wakeham, A., Khoo, W., Mitchell, K., et al. (1998). FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 279, 1954-1958.
40. Yoshimura, A., Ohkubo, T., Kiguchi, T., Jenkins, N.A., Gilbert, D.J., Copeland, N.G., Hara, T., and Miyajima, A. (1995). A novel cytokineinducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin-3 and erythropoietin receptors. EM BO J. 14, 2816-2826.
41. Zhang, J.G., Parley, A., Nicholson, S.E., Willson, T.A., Zugaro, L.M., Simpson, R.J., Moritz, R.L, Cary, D., Richardson, R., Hausmann, G., et al. (1999). The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation. Proc. Natl Acad. Sei. USA 96, 2071-2076.