Structure of the amino-terminal protein interaction domain of STAT-4

Science

Volumn 279, Issue 5353, 1998, Pages 1048-1052

  Vinkemeier, Uwe ^a   Moarefi, Ismail ^a,b   Darnell Jr , James E ^a   Kuriyan, John ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; STAT4 PROTEIN; TRANSCRIPTION FACTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; DNA BINDING; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; BINDING SITES; CELL LINE; CRYSTALLOGRAPHY, X-RAY; DNA; DNA-BINDING PROTEINS; HUMANS; HYDROGEN BONDING; INTERFERON TYPE II; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; STAT1 TRANSCRIPTION FACTOR; STAT4 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0032512661     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.279.5353.1048     Document Type: Article

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42. We thank H. Viguet and M. M. Allen for expert technical support, X. Zhu and C. M. Horvath for reagents, and the staff at BNL, especially C. Ogata, for advice in collecting MAD data. U.V. expresses special thanks to C. Harrison and F. Sicheri for valuable and generous help with DENZO and X-PLOR, and to D. E. Drake for assistance with figures. Supported by NIH grants AI34420 and AI32489 to J.E.D.