메뉴 건너뛰기




Volumn 1, Issue 1, 2000, Pages 65-69

Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; STAT2 PROTEIN; STAT2 PROTEIN, HUMAN; STAT2 PROTEIN, MOUSE; STAT4 PROTEIN; STAT4 PROTEIN, HUMAN; STAT4 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

EID: 0034231339     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/76932     Document Type: Article
Times cited : (154)

References (44)
  • 1
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A. K., Murphy, K. M. & Sher, A. Functional diversity of helper T lymphocytes. Nature 383, 787-793 (1996).
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 2
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13, 251-276 (1995).
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 3
    • 0027336689 scopus 로고
    • +T cells through IL-12 produced by Listeria-induced macrophages
    • +T cells through IL-12 produced by Listeria-induced macrophages. Science 260, 547-549 (1993).
    • (1993) Science , vol.260 , pp. 547-549
    • Hsieh, C.-S.1
  • 4
    • 0028943484 scopus 로고
    • Interleukin 12 signaling in T helper type I (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4
    • Jacobson, N. G. et al. Interleukin 12 signaling in T helper type I (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. J Exp. Med. 181, 1755-1762 (1995).
    • (1995) J Exp. Med. , vol.181 , pp. 1755-1762
    • Jacobson, N.G.1
  • 5
    • 0030758821 scopus 로고    scopus 로고
    • Studies in listeriosis show the strong symbiosis between the innate cellular system and the T-cell response
    • Unanue, E. R. Studies in listeriosis show the strong symbiosis between the innate cellular system and the T-cell response. Immunol. Rev. 158, 11-25 (1997).
    • (1997) Immunol. Rev. , vol.158 , pp. 11-25
    • Unanue, E.R.1
  • 6
    • 0029116336 scopus 로고
    • Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes
    • Bacon, C. M. et al. Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes. Proc. Natl Acad. Sci. USA 92, 7307-7311 (1995).
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 7307-7311
    • Bacon, C.M.1
  • 7
    • 0029937270 scopus 로고    scopus 로고
    • Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
    • Kaplan, M. H., Sun, Y.-L., Hoey, T. & Grusby, M. J. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382, 174-177 (1996).
    • (1996) Nature , vol.382 , pp. 174-177
    • Kaplan, M.H.1    Sun, Y.-L.2    Hoey, T.3    Grusby, M.J.4
  • 8
    • 15844396183 scopus 로고    scopus 로고
    • Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
    • Thierfelder, W. E. et al. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 382, 171-174 (1996).
    • (1996) Nature , vol.382 , pp. 171-174
    • Thierfelder, W.E.1
  • 9
    • 0028265155 scopus 로고
    • Interleukin 12 induces stable priming for interferon γ (IFN-γ) production during differentiation of human T helper (Th) cells and transient IFN-γ production in established Th2 cell clones
    • Manetti, R. et al. Interleukin 12 induces stable priming for interferon γ (IFN-γ) production during differentiation of human T helper (Th) cells and transient IFN-γ production in established Th2 cell clones. J. Exp. Med. 179, 1273-1283 (1994).
    • (1994) J. Exp. Med. , vol.179 , pp. 1273-1283
    • Manetti, R.1
  • 10
    • 0032577295 scopus 로고    scopus 로고
    • Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients
    • de Jong, R. et al. Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients. Science 280, 1435-1438 (1998).
    • (1998) Science , vol.280 , pp. 1435-1438
    • De Jong, R.1
  • 11
    • 18244428735 scopus 로고    scopus 로고
    • Impairment of mycobacterial immunity in human interieukin-12 receptor deficiency
    • Altare, R. et al. Impairment of mycobacterial immunity in human interieukin-12 receptor deficiency. Science 280, 1432-1435 (1998).
    • (1998) Science , vol.280 , pp. 1432-1435
    • Altare, R.1
  • 12
    • 0029671118 scopus 로고    scopus 로고
    • Roles of IFN-γ and IFN-α in IL-12-induced T helper cell-I development
    • Wenner, C. A., Güler, M. L., Macatonia, S. E., O'Garra, A. & Murphy, K. M. Roles of IFN-γ and IFN-α in IL-12-induced T helper cell-I development. J. Immunol. 156, 1442-1447 (1996).
    • (1996) J. Immunol. , vol.156 , pp. 1442-1447
    • Wenner, C.A.1    Güler, M.L.2    Macatonia, S.E.3    O'Garra, A.4    Murphy, K.M.5
  • 13
    • 0030892136 scopus 로고    scopus 로고
    • Selective expression of an interleukin-12 receptor component by human T helper I cells
    • Rogge, L. et al. Selective expression of an interleukin-12 receptor component by human T helper I cells. J. Exp. Med. 185, 825-831 (1997).
    • (1997) J. Exp. Med. , vol.185 , pp. 825-831
    • Rogge, L.1
  • 14
    • 0032534672 scopus 로고    scopus 로고
    • The role of Stat4 in species-specific regulation of Th cell development by type I IFNs
    • Rogge, L. et al. The role of Stat4 in species-specific regulation of Th cell development by type I IFNs. J. Immunol. 161, 6567-4574 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 6567-14574
    • Rogge, L.1
  • 15
    • 0034723184 scopus 로고    scopus 로고
    • Recruitment of Stat4 to the human IFN-α/β receptor requires activated Stat2
    • Farrar, J. D., Smith, J. D., Murphy, T. L. & Murphy, K. M. Recruitment of Stat4 to the human IFN-α/β receptor requires activated Stat2. J. Biol. Chem. 275, 2693-2697 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 2693-2697
    • Farrar, J.D.1    Smith, J.D.2    Murphy, T.L.3    Murphy, K.M.4
  • 16
    • 0026700113 scopus 로고
    • IL-4 and IFN (α and γ) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones
    • Parronchi, P. et al. IL-4 and IFN (α and γ) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones. J. Immunol. 149, 2977-2983 (1992).
    • (1992) J. Immunol. , vol.149 , pp. 2977-2983
    • Parronchi, P.1
  • 18
    • 0030469719 scopus 로고    scopus 로고
    • Activation of STAT4 by IL-12 and IFN-α. Evidence for the involvement of ligand-induced tyrosine and serine phosphorylation
    • Cho, S. et al. Activation of STAT4 by IL-12 and IFN-α. Evidence for the involvement of ligand-induced tyrosine and serine phosphorylation. J. Immunol. 157, 4781-4789 (1996).
    • (1996) J. Immunol. , vol.157 , pp. 4781-4789
    • Cho, S.1
  • 19
    • 0033593445 scopus 로고    scopus 로고
    • Identification of a STAT4 binding site in the interleukin-12 receptor required for signaling
    • Naeger, L. K., McKinney, J., Salvekar, A. & Hoey, T. Identification of a STAT4 binding site in the interleukin-12 receptor required for signaling. J. Biol. Chem. 274, 1875-1878 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 1875-1878
    • Naeger, L.K.1    McKinney, J.2    Salvekar, A.3    Hoey, T.4
  • 21
    • 0030945179 scopus 로고    scopus 로고
    • Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling
    • Li, X., Leung, S., Kerr, I. M. & Stark, G. R. Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling. Mol. Cell. Biol. 17, 2048-2056 (1997).
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2048-2056
    • Li, X.1    Leung, S.2    Kerr, I.M.3    Stark, G.R.4
  • 22
    • 0029670220 scopus 로고    scopus 로고
    • Phosphorylated interferon-α receptor I subunit (IFN-αRI) acts as a docking site for the latent form of the 113 kDa STAT2 protein
    • Yan, H. et at Phosphorylated interferon-α receptor I subunit (IFN-αRI) acts as a docking site for the latent form of the 113 kDa STAT2 protein. EMBO J. 15, 1064-1074 (1996).
    • (1996) EMBO J. , vol.15 , pp. 1064-1074
    • Yan, H.1
  • 23
    • 0029655971 scopus 로고    scopus 로고
    • Function of Stat2 protein in transcriptional activation by alpha interferon
    • Qureshi, S. A., Leung, S., Kerr, I. M., Stark, G. R. & Darnell, J. E. Function of Stat2 protein in transcriptional activation by alpha interferon. Mol. Cell. Biol. 16, 288-293 (1996).
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 288-293
    • Qureshi, S.A.1    Leung, S.2    Kerr, I.M.3    Stark, G.R.4    Darnell, J.E.5
  • 25
    • 0029872610 scopus 로고    scopus 로고
    • Direct association of STAT3 with the IFN-αR-I chain of the human type I interferon receptor
    • Yang, C.-H. et al. Direct association of STAT3 with the IFN-αR-I chain of the human type I interferon receptor. J. Biol. Chem. 271, 8057-8061 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 8057-8061
    • Yang, C.-H.1
  • 26
    • 0030999696 scopus 로고    scopus 로고
    • STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFN-αRI chain of the type I interferon receptor
    • Pfeffer, L. M. et al. STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFN-αRI chain of the type I interferon receptor. Science 276, 1418-1420 (1997).
    • (1997) Science , vol.276 , pp. 1418-1420
    • Pfeffer, L.M.1
  • 27
    • 0026327416 scopus 로고
    • High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both α and γ interferons
    • McKendry, R., John, J., Flavell, R. A., Kerr, I. M. & Stark, G. R. High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both α and γ interferons. Proc. Natl Acad. Sci. USA 88, 11455-11459 (1991).
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 11455-11459
    • McKendry, R.1    John, J.2    Flavell, R.A.3    Kerr, I.M.4    Stark, G.R.5
  • 28
    • 0028931589 scopus 로고
    • The genomic structure of the STAT genes: Multiple exons in coincident sites in Stat1 and Stat2
    • Yan, R., Qureshi, S. A., Zhong, Z., Wen, Z. & Darnell, J. E. The genomic structure of the STAT genes: multiple exons in coincident sites in Stat1 and Stat2. Nucleic Acids Res. 23, 459-463 (1995).
    • (1995) Nucleic Acids Res. , vol.23 , pp. 459-463
    • Yan, R.1    Qureshi, S.A.2    Zhong, Z.3    Wen, Z.4    Darnell, J.E.5
  • 29
    • 0033520422 scopus 로고    scopus 로고
    • Stat protein transactivation domains recruit p300/CBP through widely divergent sequences
    • Paulson, M et al. Stat protein transactivation domains recruit p300/CBP through widely divergent sequences. J. Biol. Chem. 274, 25343-25349 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 25343-25349
    • Paulson, M.1
  • 30
    • 0033230707 scopus 로고    scopus 로고
    • Murine Stat2 is uncharacteristically divergent
    • Park, C., Lecomte, M. J. & Schindler, C. Murine Stat2 is uncharacteristically divergent. Nucleic Acids Res. 27, 4191-4199 (1999).
    • (1999) Nucleic Acids Res. , vol.27 , pp. 4191-4199
    • Park, C.1    Lecomte, M.J.2    Schindler, C.3
  • 31
    • 0033212986 scopus 로고    scopus 로고
    • Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition
    • Poy, F. et al. Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition. Mol.Cell 4, 555-561 (1999).
    • (1999) Mol.Cell , vol.4 , pp. 555-561
    • Poy, F.1
  • 32
    • 0032190081 scopus 로고    scopus 로고
    • The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
    • Sayos, J. et al. The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM. Nature 395, 462-469 (1998).
    • (1998) Nature , vol.395 , pp. 462-469
    • Sayos, J.1
  • 33
    • 0026601293 scopus 로고
    • Point mutations in the ab1 SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo
    • Mayer, B. J., Jackson, P. K., Van Etten, R. A. & Baltimore, D. Point mutations in the ab1 SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo. Mol. Cell Biol. 12, 609-618 (1992).
    • (1992) Mol. Cell Biol. , vol.12 , pp. 609-618
    • Mayer, B.J.1    Jackson, P.K.2    Van Etten, R.A.3    Baltimore, D.4
  • 34
    • 0029914331 scopus 로고    scopus 로고
    • Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo
    • Kagi, D., Ledermann, B., Burki, K., Zinkernagel, R. M. & Hengartner, H. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu. Rev. Immunol. 14, 207-232 (1996).
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 207-232
    • Kagi, D.1    Ledermann, B.2    Burki, K.3    Zinkernagel, R.M.4    Hengartner, H.5
  • 35
    • 0344997344 scopus 로고
    • +,CD8-T cells and is restricted to the DR region of the MHC complex
    • +,CD8-T cells and is restricted to the DR region of the MHC complex. J. Immunol. 140, 3610-3616 (1988).
    • (1988) J. Immunol. , vol.140 , pp. 3610-3616
    • Schmid, D.S.1
  • 36
    • 0025787698 scopus 로고
    • T cell responses to herpes simplex viruses in humans
    • Schmid, D. S. & Mawle, A. C. T cell responses to herpes simplex viruses in humans. Rev. Infect Dis. 13 Suppl. 11, S946-S949 (1991).
    • (1991) Rev. Infect Dis. , vol.13 , Issue.11 SUPPL.
    • Schmid, D.S.1    Mawle, A.C.2
  • 37
    • 0026752898 scopus 로고
    • The role of T cell immunity in control of herpes simplex virus
    • Schmid, D. S. and Rouse, B. T. The role of T cell immunity in control of herpes simplex virus. Curr.Top. Microbiol. Immunol. 179, 57-74 (1992).
    • (1992) Curr.Top. Microbiol. Immunol. , vol.179 , pp. 57-74
    • Schmid, D.S.1    Rouse, B.T.2
  • 38
    • 0024550907 scopus 로고
    • HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells
    • Jacobson, S., Sekaly, R. P., Jacobson, C. L. McFarland, H. F. & Long, E. O. HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells. J. Virol. 63, 1756-1762 (1989).
    • (1989) J. Virol. , vol.63 , pp. 1756-1762
    • Jacobson, S.1    Sekaly, R.P.2    Jacobson, C.L.3    McFarland, H.F.4    Long, E.O.5
  • 39
    • 0024235598 scopus 로고
    • Recognition of intracellular measles virus antigens by HLA class II restricted measles virus-specific cytotoxic T lymphocytes
    • Jacobson, S. et al. Recognition of intracellular measles virus antigens by HLA class II restricted measles virus-specific cytotoxic T lymphocytes. Ann. NY Acad. Sci. 540, 352-353 (1988).
    • (1988) Ann. NY Acad. Sci. , vol.540 , pp. 352-353
    • Jacobson, S.1
  • 41
    • 0032531544 scopus 로고    scopus 로고
    • GATA-3-dependent enhancer activity in IL-4 gene regulation
    • Ranganath, S. H. et al. GATA-3-dependent enhancer activity in IL-4 gene regulation. J. Immunol. 161, 3822-3826 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 3822-3826
    • Ranganath, S.H.1
  • 42
    • 0032212793 scopus 로고    scopus 로고
    • Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism
    • Ouyang, W. et al. Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity 9, 745-755 (1998).
    • (1998) Immunity , vol.9 , pp. 745-755
    • Ouyang, W.1
  • 43
    • 0014757386 scopus 로고
    • A general method applicable to the search for similarities in the amino acid sequence of two proteins
    • Needleman, S. B. & Wunsch, C. D. A general method applicable to the search for similarities in the amino acid sequence of two proteins. J. Mol. Biol. 48, 443-453 (1970).
    • (1970) J. Mol. Biol. , vol.48 , pp. 443-453
    • Needleman, S.B.1    Wunsch, C.D.2
  • 44
    • 0031571196 scopus 로고    scopus 로고
    • T cell genetic background determines maintenance of IL-12 signaling. Effects on BALB/c and B10.D2T helper cell type I phenotype development
    • Güler, M. L., Jacobson, N. G., Gubler, U. & Murphy, K. M. T cell genetic background determines maintenance of IL-12 signaling. Effects on BALB/c and B10.D2T helper cell type I phenotype development. J. Immunol. 159, 1767-1774 (1997).
    • (1997) J. Immunol. , vol.159 , pp. 1767-1774
    • Güler, M.L.1    Jacobson, N.G.2    Gubler, U.3    Murphy, K.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.