Size matters: Use of YACs, BACs and PACs in transgenic animals

Transgenic Research

Volumn 10, Issue 2, 2001, Pages 83-103

  Giraldo, P ^a   Montoliu, L ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

Animal transgenesis; BAC; Bacterial artificial chromosome; Functional genomics; P1 clone; P1 derived artificial chromosome; PAC; YAC; Yeast artifical chromosome

Indexed keywords

ANIMAL BREEDING; DNA TRANSFER; GENE EXPRESSION; GENETIC COMPLEMENTATION; GENOMIC DNA; TRANSGENE; TRANSGENIC MOUSE; TRANSGENICS; YEAST ARTIFICIAL CHROMOSOME;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CHROMOSOMES, ARTIFICIAL;

ANIMALIA; BACTERIA (MICROORGANISMS); MAMMALIA; MUS MUSCULUS; ORYCTOLAGUS CUNICULUS;

EID: 0035080494     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008918913249     Document Type: Review

References (189)

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116. Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse
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122. Insertion of disease-causing mutations in BACs by homologous recombination in Escherichia coli
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183. A new logic for DNA engineering using recombination in Escherichia coli
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185. Genomic interval engineering of mice identifies a novel modulator of triglyceride production
186. Dominant expression of a 1.3 Mb human Ig kappa locus replacing mouse light chain production
187. Transgenic modification of cows milk for value-added processing
188. Visualization of alpha9 acetylcholine receptor expression in hair cells of transgenic mice containing a modified bacterial artificial chromosome
189. Faithful expression of the Myf-5 gene during mouse myogenesis requires distant control regions: A transgene approach using yeast artificial chromosomes