Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice

Nature Neuroscience

Volumn 2, Issue 8, 1999, Pages 695-698

  Lamb, Bruce T ^a,b   Bardel, Kimberly A ^a,b   Kulnane, Laura S ^a,b   Anderson, Jeff J ^c   Holtz, Greg ^c   Wagner, Steven L ^c   Sisodia, Sangram S ^d   Hoeger, Emily J ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; AMYLOID PRECURSOR PROTEIN; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONTROLLED STUDY; GENOME; LETTER; MOUSE MUTANT; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TRANSGENIC MOUSE; YEAST ARTIFICIAL CHROMOSOME;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CHROMOSOMES, ARTIFICIAL, YEAST; HUMANS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MUTATION; PRESENILIN-1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0033360402     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/11154     Document Type: Letter

References (15)

1. Selkoe, D. J. Trends Cell Biol. 8, 447-453 (1998).
2. Lamb, B. T. et al. Hum. Mol. Genet. 6, 1535-1541 (1997).
3. Lamb, B. T. et al. Nat. Genet. 5, 22-30 (1993).
4. Price, D. L. & Sisodia, S. S. Annu. Rev. Neurosci. 21, 479-505 (1998).
5. Alzheimer's Disease Collaborative Group. Nat. Genet. 11, 219-222 (1995).
6. Rogaev, E. I. et al. Genomics 40, 415-424 (1997).
7. Klafki, H. W., Wiltfang, J. & Staufenbiel, M. Anal. Biochem. 237, 24-29 (1996).
8. Wiltfang, J. et al. Electrophoresis 18, 527-532 (1997).
9. Citron, M. et al. Nat. Med. 3, 67-72 (1996).
10. Duff, K. et al. Nature 383, 710-713 (1996).
11. Borchelt, D. R. et al. Neuron 17, 1005-1013 (1996).
12. Scheuner, D. et al. Nat. Med. 2, 864-870 (1996).
13. Lemere, C. A. et al. Nat. Med. 2, 1146-1150 (1996).
14. Prasher, V. P. et al. Ann. Neurol. 43, 380-383 (1998).
15. Borchelt, D. R. et al. Neuron 19, 939-945 (1997).