Localization of distant urogenital system-, central nervous system-, and endocardium-specific transcriptional regulatory elements in the GATA-3 locus

Molecular and Cellular Biology

Volumn 19, Issue 2, 1999, Pages 1558-1568

  Lakshmanan, Ganesh ^a   Lieuw, Ken H ^a   Lim, Kim Chew ^a   Gu, Yi ^a   Grosveld, Frank ^b   Engel, James Douglas ^a   Karis, Alar ^b,c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF TARTU   (Estonia)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG;

ARTICLE; CENTRAL NERVOUS SYSTEM; EMBRYO; ENDOCARDIUM; GENE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REPORTER GENE; TRANSCRIPTION REGULATION; TRANSGENE; UROGENITAL SYSTEM; YEAST ARTIFICIAL CHROMOSOME;

ANIMALIA; MUS MUSCULUS;

EID: 0032938120     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.2.1558     Document Type: Article

References (44)

1. Arceci, R. J., A. A. J. King, M. C. Simon, S. H. Orkin, and D. B. Wilson. 1993. Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart. Mol. Cell. Biol. 13: 2235-2246.
2. Bedell, M. A., C. I. Brannan, E. P. Evans, N. G. Copeland, N. A. Jenkins, and P. J. Donovan. 1995. DNA rearrangements located over 100 kb 5′ of the Steel (Sl)-coding region in Steel-panda and Steel-contrasted mice deregulate Sl expression and cause female sterility by disrupting ovarian follicle development. Genes Dev. 9:455-470.
3. Bedell, M. A., N. A. Jenkins, and N. G. Copeland. 1996. Good genes in bad neighborhoods. Nat. Genet. 12:229-232.
4. Bungert, J., U. Dave, K. C. Lim, K. H. Lieuw, J. A. Shavit, Q. Liu, and J. D. Engel. 1995. Synergistic regulation of human beta-globin gene switching by locus control region elements HS2 and HS4. Genes Dev. 9:3083-3096.
5. Dillon, N., and F. Grosveld. 1993. Gene transcription: a practical approach. Oxford University Press, Oxford, United Kingdom.
6. Dorfman, D. M., D. B. Wilson, G. A. P. Bruns, and S. H. Orkin. 1992. Human transcription factor GATA-2: evidence for regulation of preproendothelin-1 gene expression in endothelial cells. J. Biol. Chem. 267:1279-1285.
7. Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling RNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6-13.
8. George, K. M., M. W. Leonard, M. E. Roth, K. H. Lieuw, D. Kioussis, F. Grosveld, and J. D. Engel. 1994. Embryonic expression and cloning of the murine GATA-3 gene. Development 120:2673-2686.
9. Giampaolo, A., D. Acampora, V. Zappavigna, M. Pannese, M. D'Esposito, A. Care, A. Faiella, A. Stornaiuolo, G. Russo, A. Simeone, et al. 1989. Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system. Differentiation 40:191-197.
10. Gu, Y., and J. D. Engel. Unpublished data.
11. Hanks, M., W. Wurst, L. Anson-Cartwright, A. Auerbach, and A. L. Jovner. 1995. Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science 269:679-682.
12. Hendriks, R. W., M. C. Nawijn, J. D. Engel, F. Grosveld, and A. Karis. Transcription factor GATA-3 is involved in two distinct maturation steps in early T cell development. Submitted for publication.
13. Ito, E., T. Toki, H. Ishihara, H. Ohtani, L. Gu, M. Yokohama, J. D. Engel, and M. Yamamoto. 1993. Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis. Nature 362:466-469.
14. Ko, L. J., and J. D. Engel. 1993. DNA-binding specificities of the GATA transcription factor family. Mol. Cell. Biol. 13:4011-4022.
15. Kornhauser, J. M., M. W. Leonard, M. Yamamoto, J. H. LaVail, K. E. Mayo, and J. D. Engel. 1994. Temporal and spatial changes in GATA transcription factor expression are coincident with development of the chicken optic tectum. Mol. Brain Res. 23:100-110.
16. Lakshmanan, G., and J. D. Engel. Unpublished data.
17. Lakshmanan, G., K. H. Lieuw, F. Grosveld, and J. D. Engel. Partial rescue of GATA-3 using yeast artificial chromosome transgenes. Dev. Biol., in press.
18. Laverriere, A. C., C. MacNeill, C. Mueller, R. E. Poelmann, J. B. Burch, and T. Evans. 1994. GATA-4, -5, and -6 constitute a new subfamily of transcription factors in developing heart and gut. J. Biol. Chem. 269:23177-23184.
19. Lieuw, K. H., and J. D. Engel. Unpublished data.
20. Lieuw, K. H., G. Li, Y. Zhou, F. Grosveld, and J. D. Engel. 1997. Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elements. Dev. Biol. 188:1-16.
21. Lieuw, K. H., M. E. Roth, E. Dzierzak, K. M. George, A. Karis, M. W. Leonard, K.-C. Lim, P. P. Pandolfi, F. Grosveld, and J. D. Engel. 1995. Expression and regulation of GATA-2 and GATA-3 in hematopoietic and other cell lineages, p. 15-35. In G. Stamatoyannopoulos (ed.), Biology of Hematopoiesis and Stem Cell Gene Transfer. Intercept Press, Andover, United Kingdom.
22. Lim, K.-C., and J. D. Engel. Unpublished data.
23. Liu, Q., B. Bungert, and J. D. Engel. 1997. Mutation of gene-proximal regulatory elements disrupts human epislon-, gamma-, and beta-globin expression in yeast artificial chromosome transgenic mice. Proc. Natl. Acad. Sci. USA 94:169-174.
24. Martin, D. I. K., and S. H. Orkin. 1990. Transcriptional activation and DNA-binding by the erythroid factor [GATA-1]. Genes Dev. 4:1886-1898.
25. Martin, D. I. K., L. I. Zon, G. Mutter, and S. H. Orkin. 1990. Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages. Nature 344:444-447.
26. McDevitt, M. A., R. A. Shivdasani, Y. Fujiwara, H. Yang, and S. H. Orkin. 1997. A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1. Proc. Natl. Acad. Sci. USA 94:6781-6785.
27. Merika, M., and S. H. Orkin. 1993. DNA-binding specificity of GATA family transcription factors. Mol. Cell. Biol. 13:3999-4010.
28. Molkentin, J. D., Q. Lin, S. A. Duncan, and E. N. Olson. 1997. Requirement of the transcription factor GATA-4 for heart tube formation and ventral morphogenesis. Genes Dev. 11:1061-1071.
29. Nagai, T., H. Harigae, H. Ishinara, H. Motohashi, N. Minegishi, N. Hayashi, L. Gu, B. Andres, J. D. Engel, and M. Yamamoto. 1994. Transcription factor GATA-2 is expressed in erythroid, early myeloid and CD34+ human leukemia-derived cell lines. Blood 84:1074-1084.
30. Ng, A., K. M. George, J. D. Engel, and D. I. H. Linzer. 1994. A GATA factor is necessary and sufficient for transcriptional regulation of the murine placental lactogen 1 gene promoter. Development 120:3257-3266.
31. Oosterwegel, M., J. Timmerman, J. Leiden, and H. Clevers. 1992. Expression of GATA-3 during lymphocyte differentiation and mouse embryogenesis. Dev. Immunol. 3:1-11.
32. Pandolfi, P. P., M. E. Roth, A. Karis, M. W. Leonard, E. Dzierzak, F. G. Grosveld, J. D. Engel, and M. H. Lindenbaum. 1995. Targeted disruption of the GATA-3 gene causes severe abnormalities in the nervous system and in fetal liver haemotopoiesis. Nat. Genet. 11:40-44.
33. Romeo, P.-H., M.-H. Prandini, V. Joulin, V. Mignotte, M. Prenant, W. Vainchenker, G. Marguerie, and G. Uzan. 1990. Megakaryocytic and erythrocytic lineages share specific transcription factors. Nature 344:447-449.
34. Steger, D. J., J. H. Hecht, and P. L. Mellon. 1994. GATA-binding proteins regulate the human gonadotropin α-subunit gene in the placenta and pituitary gland. Mol. Cell. Biol. 14:5592-5602.
35. Strouboulis, J., N. Dillon, and F. Grosveld. 1992. Developmental regulation of a complete 70-kb human beta-globin locus in transgenic mice. Genes Dev. 6:1857-1864.
36. Szeto, L., M. K. Fafalios, H. Zhong, A. K. Vershon, and J. R. Broach. 1997. Alpha2p controls donor preference during mating type interconversion in yeast by inactivating a recombinational enhancer of chromosome III. Genes Dev. 11:1899-1911.
37. Takahashi, S., K. Onodera, H. Motohashi, N. Suwabe, N. Hayashi, N. Yanai, Y. Nabesima, and M. Yamamoto. 1997. Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene. J. Biol. Chem. 272:12611-12615.
38. Tsai, F.-Y., G. Keller, F. C. Kuo, M. Weiss, J. Chen, M. Rasenblatt, F. W. Alt, and S. H. Orkin. 1994. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 371:221-226.
39. Whiting, J., H. Marshall, M. Cook, R. Krumlauf, P. W. J. Rigby, D. Stott, and R. K. Allemann. 1991. Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression. Genes Dev. 5:2048-2059.
40. Winston, J. F., F. Chumley, and G. R. Fink. 1983. Eviction and transplacement of mutant genes in yeast. Methods Enzymol. 101:211-228.
41. Yamamoto, M., L. J. Ko, M. W. Leonard, H. Beug, S. H. Orkin, and J. D. Engel. 1990. Activity and tissue-specific expression of the transcription factor NF-E1 [GATA] multigene family. Genes Dev. 4:1650-1662.
42. Yang, Z., L. Gu, P.-H. Romeo, D. Bories, H. Motohashi, M. Yamamoto, and J. D. Engel. 1994. Human GATA-3 trans-activation, DNA binding, and nuclear localization activities are organized into distinct structural domains. Mol. Cell. Biol. 14:2201-2212.
43. Zheng, W., and R. A. Flavell. 1997. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89:587-596.
44. Zhou, Q. Y., and R. D. Palmiter. 1995. Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell 83:1197-1209.