Imprinting of Igf2 and H19 from a 130 kb YAC transgene

Development

Volumn 124, Issue 18, 1997, Pages 3621-3632

  Ainscough, Justin F X ^a   Koidet, Tsuyoshi ^a,b   Tada, Masako ^a   Barton, Sheila ^a   Surani, M Azim ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NATIONAL INSTITUTE OF GENETICS   (Japan)

Author keywords

Genomic imprinting; Igf2 H19; Mouse; YAC transgenes

Indexed keywords

SOMATOMEDIN B;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMBRYO; ENHANCER REGION; GENE; GENE DOSAGE; GENE EXPRESSION; GENE NUMBER; GENE REPRESSION; GENOME IMPRINTING; MESODERM; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REPORTER GENE; SILENT GENE; TRANSGENE; YEAST ARTIFICIAL CHROMOSOME;

ANIMALS; CHROMOSOMES, ARTIFICIAL, YEAST; DNA METHYLATION; EMBRYO; ENHANCER ELEMENTS (GENETICS); FEMALE; GENE DOSAGE; GENES, REPORTER; GENOMIC IMPRINTING; INSULIN-LIKE GROWTH FACTOR II; MALE; MESODERM; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; MODELS, GENETIC; MUSCLE PROTEINS; PHENOTYPE; RNA, UNTRANSLATED; TRANSGENES;

ANIMALIA;

EID: 0030840328     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Ainscough, J. F-X. and Surani, M. A. (1996). Organisation and control of imprinted genes: The common features. In Epigenetic Mechanisms of Gene Regulation (ed. V. E. A. Russo, R. A. Martienssen and A. D. Riggs), pp. 173-194. CSHL Press.
2. Allen, N. D., Barton, S. C., Surani, M. A. H. and Reik, W. (1987). Production of transgenic mice. In Mammalian Development. A Practical Approach (ed. M. Monk), pp. 217-233. IRL press, Oxford Washington DC.
3. Bartolomei, M. S., Webber, A. L., Brunkow, M. E. and Tilghman, S. M. (1993). Epigenetic mechanisms underlying the imprinting of the mouse H19 gene. Genes Dev 7, 1663-1673.
4. Bartolomei, M. S., Zemel, S. and Tilghman, S. M. (1991). Parental imprinting of the mouse H19 gene. Nature 351, 153-155.
5. Beechey, C. and Cattanach, B. (1995). Genetic imprinting map. Mouse Genome 93, 89-92.
6. Bestor, T. H. and Tycko, B. (1996). Creation of genomic methylation patterns. Nature Genet. 12, 363-367.
7. Brown, K. W., Villar, A. J., Bickmore, W., ClaytonSmith, J., Catchpoole, D., Maher, E. R. and Reik, W. (1996). Imprinting mutation in the Beckwith-Wiedemann syndrome leads to biallelic IGF2 expression through an H19 independent pathway. Hum. Mol. Genet. 5, 2027-32.
8. Brunkow, M. E. and Tilghman, S. M. (1991). Ectopic expression of the H19 gene in mice causes prenatal lethality. Genes Dev. 5, 1092-1101.
9. Cattanach, B. M. and Kirk, M. (1985). Differential activity of maternally and paternally derived chromosome regions in mice. Nature 315, 496-498.
10. Church, G. M. and Gilbert, W. (1984). Genomic sequencing. Proc. Natl. Acad. Sci. USA 81, 1991-1995.
11. DeChiara, T. M., Robertson, E. J. and Efstratiadis, A. (1991). Parental imprinting of the mouse insulin-like growth factor II gene. Cell 64, 849-859.
12. Efstratiadis, A. (1994). Parental imprinting of autosomal mammalian genes. Cur. Opin. Genet. Dev. 4, 265-280.
13. Elson, D. A. and Bartolomei, M. S. (1997). A 5′ differentially methylated sequence and the 3′-flanking region are necessary for H19 transgene imprinting. Mol. Cell Biol. 17, 309-317.
14. Feil, R., Walter, J., Allen, N. D. and Reik, W. (1994). Developmental control of allelic methylation in the imprinted mouse Igf2 and HI9 genes. Development 120, 2933-2943.
15. Ferguson-Smith, A. C., Cattanach, B. M., Barton, S. C., Beechey, C. V. and Surani, M. A. (1991). Molecular and embryological investigations of parental imprinting on mouse chromosome 7. Nature 351, 667-670.
16. Ferguson-Smith, A. C., Sasaki, H., Cattanach, B. M. and Surani, M. A. (1993). Parental-origin-specific modification of the mouse H19 gene. Nature 362, 751-755.
17. Giannoukakis, N., Deal, C., Paquette, J., Goodyer, C. and Polychronakos, C. (1993). Parental genomic imprinting of the human IGF-2 gene. Nature Gene 4, 98-101.
18. Giddings, S. J., King, C. D., Harman, K. W., Flood, J. F. and Carnaghi, L. R. (1994). Allele specific inactivation of insulin 1 and 2, in the mouse yolk sac, indicates imprinting. Nature Genet. 6, 310-313.
19. Guillemot, F., et al. (1995). Genomic imprinting of Mash2, a mouse gene required for trophoblast development. Nature Genet. 9, 235-242.
20. Hao, Y., Crenshaw, T., Moulton, T., Newcomb, E. and Tycko, B. (1993). Tumour-suppressor activity of H19 RNA. Nature 365, 764-767.
21. KIP2, a cyclin-dependent kinase inhibitor, in mouse. Nature Genet 11, 204-206.
22. Hoovers, J. M. N., et al. (1995). Multiple genetic loci within 11p15 defined by Beckwith-Wiedemann syndrome rearrangement breakpoints and subchromosomal transferable fragments. Proc. Natl. Acad. Sci. USA 92, 12456-12460.
23. Jinno, Y., et al. (1995). Establishment of functional imprinting of the H19 gene in human developing placentae. Nature Genet. 10, 318-324.
24. Kitsberg, D., Selig, S., Brandeis, M., Simon, I., Keshet, I., Driscoll, D. J., Nicholls, R. D. and Cedar, H. (1993). Allele-specific replication timing of imprinted gene regions. Nature 364, 459-463.
25. Koide, T., Ainscough, J., Wijgerde, M. and Surani, M. A. (1994). Comparative analysis of Igf-2/H19 imprinted domain: identification of a highly conserved intergenic DNase I hypersensitive region. Genomics 24, 1-8.
26. Kou, K. and Rotwein, P. (1993). Transcriptional activation of the Insulin-like growth factor-II gene during myoblast differentiation. Mol. Endocrin. 7, 291- 302.
27. LaSalle, J. M. and Lalande, M. (1996). Homologous association of oppositely imprinted chromosomal domains. Science 272, 725-728.
28. Lee, J., Pintar, J. and Efstratiadis, A. (1990). Pattern of the insulin-like growth factor II gene expression during early mouse development. Development 110, 151-159.
29. Lee, J. E., Tantravahi, U., Boyle, A. L. and Efstratiadis, A. (1993). Parental imprinting of an Igf-2 transgene. Mol. Reprod. Dev. 35, 382-390.
30. Lee, J. T., Strauss, W. M., Dausman, J. A. and Jaenisch, R. (1996). A 450 kb transgene displays properties of the mammalian X-inactivation center. Cell 86, 83-94.
31. Lee, M. P., Hu, R.-J., Johnson, L. A. and Feinberg, A. P. (1997). Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements. Nature Genet. 15, 181- 185.
32. Leighton, P., Saam, J., Ingram, R., Stewart, C. and Tilghman, S. (1995a). An enhancer deletion affects both H19 and Igf2 expression. Genes Dev. 9, 2079-2089.
33. Leighton, P. A., Ingram, R. S., Eggenschwiler, J., Efstratiadis, A. and Tilghman, S. M. (1995b). Disruption of imprinting caused by deletion of the H19 gene region in mice. Nature 375, 34-39.
34. Li, E., Beard, C. and Jaenisch, R. (1993). Role of DNA methylation in genomic imprinting. Nature 366, 362-365.
35. Li, E., Bestor, T. H. and Jaenisch, R. (1992). Targeted mutation of the DNA methyltransferase gene result in embryonic lethality. Cell 69, 915-926.
36. Lyko, F., Brenton, J. D., Surani, M. A. and Paro, R. (1997). An imprinting element from the mouse H19 locus functions as a silencer in Drosophila. Nature Genet. 16, 171-173.
37. KIP2, on chromosome 11p15. Proc. Natl. Acad. Sci. USA 93, 3026-3030.
38. Mutter, G. L., Stewart, C. L., Chaponot, M. L. and Pomponio, R. J. (1993). Oppositely imprinted genes H19 and Insulin-like growth factor 2 are coexpressed in human androgenetic trophoblast. Am. J. Hum. Genet. 53, 1096-1102.
39. Ohlsson, R., Nystrom, A., Pfeifer-Ohlsson, S., Tohonen, V., Hedborg, F., Schofield, P., Flam, F. and Ekstrom, J. (1993). IGF2 is parentally imprinted during human embryogenesis and in the Beckwith-Wiedemann syndrome. Nature Genet. 4, 94-97.
40. Pfeifer, K., Leighton, P. A. and Tilghman, S. M. (1996). The structural H19 gene is required for transgene imprinting. Proc. Natl. Acad. Sci. USA 93, 13876-13883.
41. Pinkel, D., Straume, T. and Gray, J. W. (1986). Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridisation. Proc. Natl. Acad. Sci. USA 83, 2934-2938.
42. Poirier, F., Chan, C.-T. J., Timmons, P., Robertson, E. J., Evans, M. J. and Rigby, P. W. J. (1991). The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo. Development 113, 1105-1114.
43. Reik, W., Brown, K. W., Schneid, H., Le Bouc, Y., Bickmore, W. and Maher, E. R. (1995). Imprinting mutations in the Beckwith-Wiedemann syndrome suggested by an altered imprinting pattern in the IGF2-H19 domain. Hum. Mol. Genet. 4, 2379-2385.
44. Reik, W., Howlett, S. K. and Surani, M. A. (1990). Imprinting by DNA methylation: from transgenes to endogenous gene sequences. Development Supplement, 99-106.
45. Ripoche, M.-A., Kress, C., Poirier, F. and Dandolo, L. (1997). Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element. Genes Dev 11, 1596-1604.
46. Sasaki, H., Ferguson-Smith, A. C., Shum, A. S. W., Barton, S. C. and Surani, M. A. (1995). Temporal and spatial regulation of H19 imprinting in early embryogenesis. Development 121, 4195-4202.
47. Sasaki, H., Jones, P. A., Chaillet, J. R., Ferguson-Smith, A. C., Barton, S. C., Reik, W. and Surani, M. A. (1992). Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene. Genes Dev. 6, 1843-1856.
48. Schedl, A., Montoliu, L., Kelsey, G. and Schutz, G. (1993). A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice. Nature 362, 258-261.
49. Schedl, A., Ross, A., Lee, M., Engelkamp, D., Rashbass, P., van Heyningen, V. and Hastie, N. D. (1996). Influence of PAX6 gene dosage on development: Overexpression causes severe eye abnormalities. Cell 86, 71-82.
50. Searle, A. G. and Beechey, C. V. (1990). Genome imprinting phenomena on mouse chromosome 7. Genetics Res. 56, 237-244.
51. Stylianopoulou, F., Efstratiadis, A., Herbert, J. and Pintar, J. (1988). Pattern of the insulin-like growth factor II gene expression during rat embryogenesis. Development 103, 497-506.
52. Svensson, K., Walsh, C., Fundele, R. and Ohlsson, R. (1995). H19 is imprinted in the choroid plexus and leptomeninges of the mouse foetus. Mechanisms of Development 51, 31-37.
53. Tremblay, K. D., Saam, J. R., Ingram, R. S., Tilghman, S. M. and Bartolomei, M. S. (1995). A paternal-specific methylation imprint marks the alleles of the mouse H19 gene. Nature Genet.9, 407-413.
54. Wijgerde, M., Grosveld, F. and Fraser, P. (1995). Transcription complex stability and chromatin dynamics in vivo. Nature 377, 209-213.
55. Yoo-Warren, H., Pachnis, V., Ingram, R. S. and Tilghman, S. M. (1988). Two regulatory domains flank the mouse H19 gene Mol. Cell Biol. 8, 4707-4715.
56. Yuan, L., Qian, N. and Tycko, B. (1996). An extended region of biallelic gene expression and rodent-human synteny downstream of the imprinted H19 gene on chromosome 11p15.5. Hum. Mol. Genet. 5, 1931-1937.
57. Zemel, S., Bartolomei, M. S. and Tilghman, S. M. (1992). Physical linkage of two mammalian imprinted genes, H19 and Igf2. Nat Genet. 2, 61-65.
58. Zhang, Y., Shields, T., Crenshaw, T., Hao, Y., Moulton, T. and Tycko, B. (1993). Imprinting of Human H19: allele specific CpG methylation, loss of the active allele in Wilm's tumor and potential for somatic allele switching. Am. J. Hum. Genet. 53, 113-124.
59. Zhang, Y. and Tycko, B. (1992). Monoallelic expression of the human H19 gene. Nature Genet. 1, 40-44.