Macrophage specific overexpression of the human macrophage scavenger receptor in transgenic mice, using a 180-kb yeast artificial chromosome, leads to enhanced foam cell formation of isolated peritoneal macrophages

Atherosclerosis

Volumn 147, Issue 2, 1999, Pages 339-347

  De Winther, Menno P J ^a,b   Van Dijk, Ko Willems ^a   Van Vlijmen, Bart J M ^b,c   Gijbels, Marion J J ^a   Heus, Joris J ^a   Wijers, Edwin R ^a   Van Den Bos, Alida C ^a   Breuer, Marco ^a   Frants, Rune R ^a   Havekes, Louis M ^a,b   Hofker, Marten H ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b TNO   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Acetyl low density lipoprotein; Macrophage scavenger receptor; Transgenics; Yeast artificial chromosome

Indexed keywords

ACETYL LOW DENSITY LIPOPROTEIN; CHOLESTEROL ESTER; SCAVENGER RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATHEROGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; FOAM CELL; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; TRANSGENIC MOUSE; YEAST ARTIFICIAL CHROMOSOME;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; CHROMOSOMES, ARTIFICIAL, YEAST; DISEASE MODELS, ANIMAL; FOAM CELLS; GENE EXPRESSION; HUMANS; KUPFFER CELLS; LIPOPROTEINS, LDL; MACROPHAGES, PERITONEAL; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECEPTORS, IMMUNOLOGIC; RECEPTORS, SCAVENGER; RNA, MESSENGER; SCAVENGER RECEPTORS, CLASS A; SENSITIVITY AND SPECIFICITY; SPECIES SPECIFICITY; TISSUE DISTRIBUTION;

EID: 0032740398     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(99)00204-X     Document Type: Article

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