Roles for p53 in growth arrest and apoptosis: Putting on the brakes after genotoxic stress

Oncogene

Volumn 17, Issue 25, 1998, Pages 3287-3299

  Amundson, Sally A ^a   Myers, Timothy G ^a   Fornace Jr , Albert J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Cell cycle; Functional genomics; p53; Stress response

Indexed keywords

PROTEIN P53;

APOPTOSIS; ARTICLE; CELL CYCLE; DNA REPAIR; GENOTOXICITY; GROWTH DISORDER; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSACTIVATION; TUMOR SUPPRESSOR GENE;

MAMMALIA;

EID: 0032411599     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202576     Document Type: Article

References (212)

1. Agarwal ML, Agarwal A, Taylor WR and Stark GR. (1995). Proc. Natl. Acad. Sci. USA, 92, 8493-8497.
2. Amundson SA, Zhan Q, Penn LZ and Fornace Jr AJ. (1998). Oncogene, in press.
3. Andres JL, Fan S, Turkel GJ, Wang JA, Twu NF, Yuan RQ, Lamszus K, Goldberg ID and Rosen EM. (1998). Oncogene, 16, 2229-2241.
4. Askew DS, Ashmun RA, Simmons BC and Cleveland JL. (1991). Oncogene, 6, 1915-1922.
5. Attardi LD, Lowe SW, Brugarolas J and Jacks T. (1996). EMBO J., 15, 3693-3701.
6. Bae I, Smith ML, Sheikh MS, Zhan Q, Scudiero DA, Friend SH, O'Connor PM and Fornace Jr AJ. (1996). Cancer Res., 56, 840-847.
7. Bai RL, Paull KD, Herald CL, Malspeis L, Pettit GR and Hamel E. (1991). J. Biol. Chem., 266, 15882-15889.
8. Bakalkin G, Yakovleva T, Selivanova G, Magnusson KP, Szekely L, Kiseleva E, Klein G, Terenius L and Wiman KG. (1994). Proc. Natl. Acad. Sci. USA, 91, 413-417.
9. Barak Y, Juven T, Haffner R and Oren M. (1993). EMBO J., 12, 461-468.
10. Barlow C, Brown KD, Deng CX, Tagle DA and Wynshaw-Boris A. (1997). Nat. Genet., 17, 453-456.
11. Baskaran R, Wood LD, Whitaker LL, Canman CE, Morgan SE, Xu Y, Barlow C, Baltimore D, Wynshaw-Boris A, Kastan MB and Wang JY. (1997). Nature, 387, 516-519.
12. Bian J and Sun Y. (1997). Proc. Natl. Acad. Sci. USA, 94, 14753-14758.
13. Blaydes JP and Wynford-Thomas D. (1998). Oncogene, 16, 3317-3322.
14. Boise LH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nunez G and Thompson CB. (1993). Cell, 74, 597-608.
15. Brady HJ, Salomons GS, Bobeldijk RC and Berns AJ. (1996). EMBO J., 15, 1221-1230.
16. Brugarolas J, Chandrasekaran C, Gordon JI, Beach D, Jacks T and Hannon GJ. (1995). Nature, 377, 552-557.
17. Caelles C, Heimberg A and Karin M. (1994). Nature, 370, 220-223.
18. Canman CE, Gilmer TM, Coutts SB and Kastan MB. (1995). Genes Dev., 9, 600-611.
19. Canman CE, Wolff AC, Chen CY, Fornace Jr AJ and Kastan MB. (1994). Cancer Res., 54, 5054-5058.
20. Carrier F, Georgel PT, Pourquier P, Blake M, Kontny HU, Antinore MJ, Gariboldi M, Myers TG, Weinstein J, Pommier Y and Fornace Jr AJ. (1998). submitted for publication.
21. Chang TH, Ray FA, Thompson DA and Schlegel R. (1997). Oncogene, 14, 2383-2393.
22. Chellappan SP, Hiebert S, Mudryj M, Horowitz JM and Nevins JR. (1991). Cell, 65, 1053-1061.
23. Chen CY, Oliner JD, Zhan Q, Fornace Jr AJ, Vogelstein B and Kastan MB. (1994). Proc. Natl. Acad. Sci. USA, 91, 2684-2688.
24. Cho Y, Gorina S, Jeffrey PD and Pavletich NP. (1994). Science, 265, 346-355.
25. Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML and Wyllie AH. (1993). Nature, 362, 849-852.
26. Collins MK, Marvel J, Malde P and Lopez-Rivas A. (1992). J. Exp. Med., 176, 1043-1051.
27. Cross SM, Sanchez CA, Morgan CA, Schimke MK, Ramel S. Idzerda RL, Raskind WH and Reid BJ. (1995). Science, 267, 1353-1356.
28. Deng C, Zhang P, Harper JW, Elledge SJ and Leder P. (1995). Cell, 82, 675-684.
29. DeRisi J, Penland L, Brown PO, Bittner ML, Meltzer PS, Ray M, Chen Y, Su YA and Trent JM. (1996). Nat. Genet., 14, 457-460.
30. Di Leonardo A, Linke SP, Clarkin K and Wahl GM. (1994). Genes Dev., 8, 2540-2551.
31. Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, Moore M, Finlay C and Levine AJ. (1993). Nat. Genet., 4, 42-46.
32. Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery Jr CA, Butel JS and Bradley A. (1992). Nature, 356, 215-221.
33. Donehower LA, Harvey M, Vogel H, McArthur MJ, Montgomery CAJ, Park SH, Thompson T, Ford RJ and Bradley A. (1995). Mol. Carcinog., 14, 16-22.
34. Dulic V, Stein GH, Far DF and Reed SI. (1998). Mol. Cell. Biol., 18, 546-557.
35. El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW and Vogelstein B. (1993). Cell, 75, 817-825.
36. El-Deiry WS, Harper JW, O'Connor PM, Velculescu VE, Canman CE, Jackman J, Pietenpol JA, Burrell M, Hill DE, Wang Y, et al. (1994). Cancer Res., 54, 1169-1174.
37. Elledge SJ. (1996). Science, 274, 1664-1672.
38. Enari M, Hug H and Nagata S. (1995). Nature, 375, 78-81.
39. Ermolaeva O, Rastogi M, Pruitt KD, Schiller GD, Bittner ML, Chen Y, Simon R, Meltzer P, Trent JM and Boguski MS. (1998). Nat. Genet., 20, 19-23.
40. Evan GI, Hancock DC et al., (1992). Cell, 69, 119-128.
41. Fan S, Smith ML, Rivet II DJ, Duba D, Zhan Q, Kohn KW, Fornace Jr AJ and O'Connor PM. (1995). Cancer Res., 55, 1649-1654.
42. Fields S and Jang SK. (1990). Science, 249, 1046-1049.
43. Ford JM and Hanawalt PC. (1995). Proc. Natl. Acad. Sci. USA, 92, 8876-8880.
44. Ford JM and Hanawalt PC. (1997). J. Biol. Chem., 272, 28073-28080.
45. Freije JM, Lawrence JA, Hollingshead MG, De la Rosa A, Narayanan V, Grever M, Sausville EA, Paull K and Steeg PS. (1997). Nat. Med., 3, 395-401.
46. Fukasawa K, Choi T, Kuriyama R, Rulong S and Vande Woude GF. (1996). Science, 271, 1744-1747.
47. Gadbois DM, Bradbury EM and Lehnert BE. (1997). Cancer Res., 57, 1151-1156.
48. Ginsberg D, Mechta F, Yaniv M and Oren M. (1991). Proc. Natl. Acad. Sci. USA, 88, 9979-9983.
49. Goga A, Liu X, Hambuch TM, Senechal K, Major E, Berk AJ, Witte ON and Sawyers CL. (1995). Oncogene, 11, 791-799.
50. Gottlieb E, Lindner S and Oren M. (1996). Cell Growth Differ., 7, 301-310.
51. Gottlieb E and Oren M. (1998). EMBO J., 17, 3587-3596.
52. Gottlieb TM and Oren M. (1996). Biochim. Biophys. Acta, 1287, 77-102.
53. Gottschalk AR, Boise LH, Thompson CB and Quintans J. (1994). Proc. Natl. Acad. Sci. USA, 91, 7350-7354.
54. Grever MR, Schepartz SA and Chabner BA. (1992). Semin. Oncol., 19, 622-638.
55. Gualberto A, Aldape K, Kozakiewicz K and Tlsty TD. (1998). Proc. Natl. Acad. Sci. USA, 95, 5166-5171.
56. Guillouf C, Rosselli F, Krishnaraju K, Moustacchi E, Hoffman B and Liebermann DA. (1995). Oncogene, 10, 2263-2270.
57. Gujuluva CN, Baek JH, Shin KH, Cherrick HM and Park NH. (1994). Oncogene, 9, 1819-1827.
58. Hall SR, Campbell LE and Meek DW. (1996). Nucleic Acids Res., 24, 1119-1126.
59. Harper JW, Adami GR, Wei N, Keyomarsi K and Elledge SJ. (1993). Cell, 75, 805-816.
60. Hartwell LH and Kastan MB. (1994). Science, 266, 1821-1828.
61. Haupt Y, Rowan S, Shaulian E, Vousden KH and Oren M. (1995). Genes Dev., 9, 2170-2183.
62. Haupt Y and Oren M. (1996). Behring Inst. Mitt., 97, 32-59.
63. Hecker D, Page G, Lohrum M, Weiland S and Scheidtmann KH. (1996). Oncogene, 12, 953-961.
64. Hermeking H and Eick D. (1994). Science, 265, 2091-2093.
65. Hermeking H, Funk JO, Reichert M, Ellwart JW and Eick D. (1995). Oncogene, 11, 1409-1415.
66. Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler K and Vogelstein B. (1997). Molecular Cell, 1, 3-11.
67. Hollander MC, Alamo I, Jackman J, McBride OW and Fornace Jr AJ. (1993). J. Biol. Chem., 268, 24385-24393.
68. Hollander MC, Zhan Q, Bae I, Iglesias M, Woodworth C and Fornace Jr AJ. (1997). J. Biol. Chem., 272, 13731-13737.
69. Hollstein M, Sidransky D, Vogelstein B and Harris CC. (1991). Science, 253, 49-53.
70. Huang LC, Clarkin KC and Wahl GM. (1996). Proc. Natl. Acad. Sci. USA, 93, 4827-4832.
71. Iliakis G. (1997). Semin. Oncol., 24, 602-615.
72. Israeli D, Tessler E, Haupt Y, Elkeles A, Wilder S, Amson R, Telerman A and Oren M. (1997). EMBO J., 16, 4384-4392.
73. Itoh N, Tsujimoto Y and Nagata S. (1993). J. Immunol., 151, 621-627.
74. Iwamoto KS, Mizuno T, Ito T, Tsuyama N, Kyoizumi S and Seyama T. (1996). Cancer Res., 56, 3862-3865.
75. Jayaraman L and Prives C. (1995). Cell, 81, 10231-11029.
76. Johnson DG, Schwarz JK, Cress WD and Nevins JR. (1993). Nature, 365, 349-352.
77. Jones SN, Roe AE, Donehower LA and Bradley A. (1995). Nature, 378, 206-208.
78. Jost CA, Marin MC and Kaelin WGJ. (1997). Nature, 389, 191-194.
79. Kaghad M, Bonnet H, Yang A, Creancier L, Biscan JC, Valent A, Minty A, Chalon P, Lelias JM, Dumont X, Ferrara P, McKeon F and Caput D. (1997). Cell, 90, 809-819.
80. Kamijo T, Weber JD, Zambetti G, Zindy F, Roussel MF and Sherr CJ. (1998). Proc. Natl. Acad. Sci. USA, 95, 8292-8297.
81. Kao GD, McKenna WG, Maity A, Blank K and Muschel RJ. (1997). Cancer Res., 57, 753-758.
82. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B and Craig RW. (1991). Cancer Res., 51, 6304-6311.
83. Kastan MB, Zhan Q, El-Deiry WS, Carrier F, Jacks T, Walsh WV, Plunkett BS, Vogelstein B and Fornace Jr AJ. (1992). Cell, 71, 587-597.
84. Khanna KK and Lavin MF. (1993). Oncogene, 8, 3307-3312.
85. Kharbanda S, Ren R, Pandey P. Shafman TD, Feller SM, Weichselbaum RR and Kufe DW. (1995). Nature, 376, 785-788.
86. Koo HM, Monks A, Mikheev A, Rubinstein LV, Gray-Goodrich M, McWilliams MJ, Alvord WG, Oie HK, Gazdar AF, Paull KD, Zarbl H and Vande Woude GF. (1996). Cancer Res., 56, 5211-5216.
87. Koutsoukos AD, Rubinstein LV, Faraggi D, Simon RM, Kalyandrug S, Weinstein JN, Kohn KW and Paull KD. (1994). Stat. Med., 13, 719-730.
88. Krek W and Nigg EA. (1991). EMBO J., 10, 3331-3341.
89. Kubbutat MH and Vousden KH. (1998). Mol. Med. Today, 4, 250-256.
90. Lanni JS and Jacks T. (1998). Mol. Cell. Biol., 18, 1055-1064.
91. Lavigueur A, Maltby V, Mock D, Rossant J, Pawson T and Bernstein A. (1989). Mol. Cell Biol., 9, 3982-3991.
92. Lee JS, Paull K, Alvarez M, Hose C, Monks A, Grever M, Fojo AT and Bates SE. (1994). Mol. Pharmacol., 46, 627-638.
93. Lee S, Elenbaas B, Levine A and Griffith J. (1995). Cell, 81, 1013-1020.
94. Lee TC, Li L, Philipson L and Ziff EB. (1997). Proc. Natl. Acad. Sci. USA, 94, 12886-12891.
95. Levine AJ, Momand J and Finlay CA. (1991). Nature, 351, 453-456.
96. Li G, Mitchell DL, Ho VC, Reed JC and Tron VA. (1996). Am. J. Pathol., 148, 1113-1123.
97. Linke SP, Clarkin KC and Wahl GM. (1997). Cancer Res., 57, 1171-1179.
98. Lotem J and Sachs L. (1993). Blood, 82, 1092-1096.
99. Lowe SW, Schmitt EM, Smith SW, Osborne BA and Jacks T. (1993). Nature, 362, 847-849.
100. MacFarlane M, Ahmad M, Srinivasala SM, Fernandes-Alnemri T, Cohen GM and Alnemri ES. (1997). J. Biol. Chem., 272, 25417-25420.
101. Mack DH, Vartikar J, Pipas JM and Laimins LA. (1993). Nature, 363, 281-283.
102. Madden SL, Galella EA, Zhu J, Bertelsen AH and Beaudry GA. (1997). Oncogene, 15, 1079-1085.
103. Maheswaran S, Park S, Bernard A, Morris JF, Rauscher III FJ, Hill DE and Haber DA. (1993). Proc. Natl. Acad. Sci. USA, 90, 5100-5104.
104. Maheswaran S, Englert C, Bennett P, Heinrich G and Haber DA. (1995). Genes Dev., 9, 2143-2156.
105. Mai M, Yokomizo A, Qian C, Yang P, Tindall DJ, Smith DI and Liu W. (1998). Cancer Res., 58, 2347-2349.
106. Maity A, McKenna WG and Muschel RJ. (1995). EMBO J., 14, 603-609.
107. Maltzman W and Czyzyk L. (1984). Mol. Cell. Biol., 4, 1689-1694.
108. Marhin WW, Chen S, Facchini LM, Fornace Jr AJ and Penn LZ. (1997). Oncogene, 14, 2825-2834.
109. Matsushime H, Ewen ME, Strom DK, Kato JY, Hanks SK, Roussel MF and Sherr CJ. (1992). Cell, 71, 323-334.
110. Medema RH, Klompmaker R, Smits VA and Rijksen G. (1998). Oncogene, 16, 431-441.
111. Meek DW. (1994). Semin. Cancer Biol., 5, 203-210.
112. Meek DW. (1998). Cell Signal, 10, 159-166.
113. Minn AJ, Boise LH and Thompson CB. (1996). Genes Dev., 10, 2621-2631.
114. Miyashita T, Harigai M, Hanada M and Reed JC. (1994a). Cancer Res., 54, 3131-3135.
115. Miyashita T, Krajewski S, Krajewska M, Wang HG, Lin HK, Liebermann DA, Hoffman B and Reed JC. (1994b). Oncogene, 9, 1799-1805.
116. Moberg KH, Tyndall WA and Hall DJ. (1992). J. Cell. Biochem., 49, 208-215.
117. Monks A, Scudiero D, Skehan P, Shoemaker R, Paull K, Vistica D, Hose C, Langley J, Cronise P, Vaigro-Wolff A, et al. (1991). J. Natl. Cancer Inst., 83, 757-766.
118. Montes de Oca Luna R, Wagner DS and Lozano G. (1995). Nature, 378, 203-206.
119. Murphy M, Hinman A and Levine AJ. (1996). Genes Dev., 10, 2971-2980.
120. Muschel RJ, Zhang HB, Iliakis G and McKenna WG. (1991). Cancer Res., 51, 5113-5117.
121. Myers TG, Anderson NL, Waltham M, Li G, Buolamwini JK, Scudiero DA, Paull KD, Sausville EA and Weinstein JN. (1997). Electrophoresis, 18, 647-653.
122. Nelson WG and Kastan MB. (1994). Mol. Cell. Biol., 14, 1815-1823.
123. Nevins JR. (1992). Science, 258, 424-429.
124. Niculescu ABr, Chen X, Smeets M, Hengst L, Prives C and Reed SI. (1998). Mol. Cell. Biol., 18, 629-643.
125. O'Connor PM, Jackman J, Jondle D, Bhatia K, Magrath I and Kohn KW. (1993). Cancer Res., 53, 4776-4780.
126. O'Connor PM. (1997). Cancer Surv., 29, 151-182.
127. O'Connor PM, Jackman J, Bae I, Myers TG, Fan S, Mutoh M, Scudiero D, Monks A, Sausville EA, Weinstein JN, Friend S, Fornace Jr AJ and Kohn KW. (1997). Cancer Res., 57, 4285-4300.
128. Oliner JD, Pietenpol JA, Thiagalingam S, Gyuris J, Kinzler KW and Vogelstein B. (1993). Nature, 362, 857-860.
129. Oltvai ZN, Milliman CL and Korsmeyer SJ. (1993). Cell, 74, 609-619.
130. Osada M, Ohha M, Kawahara C, Ishioka C, Kanamaru R, Katoh I, Ikawa Y, Nimura V, Nakagawara A, Obinata M and Ikawa S. (1998). Nat. Med., 4, 839-843.
131. Owen-Schaub LB, Zhang W, Cusack JC, Angelo LS, Santee SM, Fujiwara T, Roth JA, Deisseroth AB, Zhang WW, Kruzel E, et al. (1995). Mol. Cell. Biology, 15, 3032-3040.
132. Paggi MG, Baldi A, Bonetto F and Giordano A. (1996). J. Cell. Biochem., 62, 418-430.
133. Pan G, Ni J, Wei YF, Yu G, Gentz R and Dixit VM. (1997). Science, 277, 815-818.
134. Papathanasiou MA, Kerr NC, Robbins JH, McBride OW, Alamo IJ, Barrett SF, Hickson ID and Fornace Jr AJ. (1991). Mol. Cell. Biol., 11, 1009-1016.
135. Paull KD, Lin CM, Malspeis L and Hamel E. (1992). Cancer Res., 52, 3892-3900.
136. Paull KD, Hamel E and Malspeis L. (1995). Foye WO (ed 1 .), American Chemical Society: Wash., DC. pp 9-95.
137. Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS and Piwnica-Worms H. (1997). Science, 277, 1501-1505.
138. Philipp A, Schneider A, Vasrik I, Finke K, Xiong Y, Beach D, Alitalo K and Eilers M. (1994). Mol. Cell. Biol., 14, 4032-4043.
139. Pietenpol JA, Tokino T, Thiagalingam S, El-Deiry WS, Kinzler KW and Vogelstein B. (1994). Proc. Natl. Acad. Sci. USA, 91, 1998-2002.
140. Pohl J, Goldfinger N, Radler-Pohl A, Rotter V and Schirrmacher V. (1988). Mol. Cell. Biol., 8, 2078-2081.
141. Polyak K, Xia Y, Zweler JL, Kinzler KW and Vogelstein B. (1997). Nature, 389, 300-306.
142. Pomerantz J, Schreiber-Agus N, Liegeois NJ, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee HW, Cordon-Cardo C and DePinho RA. (1998). Cell, 92, 713-723.
143. Powell SN, DeFrank JS, Connell P, Eogan M, Preffer F, Dombkowski D, Tang W and Friend S. (1995). Cancer Res., 55, 1643-1648.
144. Prabhu NS, Somasundaram K, Satyamoorthy K, Herlyn M and El-Deiry WS. (1998). Int. J. Oncol., 13, 5-9.
145. Price BD and Park SJ. (1994). Cancer Res., 54, 896-899.
146. Prisco M, Hongo A, Rizzo MG, Sacchi A and Baserga R. (1997). Mol. Cell. Biol., 17, 1084-1092.
147. Qin X, Livingston DM, Kaelin Jr WG and Adams PD. (1994). Proc. Natl. Acad. Sci. USA, 91, 10918-10922.
148. Radford IR, Murphy TK, Radley JM and Ellis SL. (1994). Int. J. Radiat. Biol., 65, 217-227.
149. Reed M, Woelker B, Wang P, Wang Y, Anderson ME and Tegtmeyer P. (1995). Proc. Natl. Acad. Sci. USA, 92, 9455-9459.
150. Rouault JP, Prevot D, Berthet C, Birot AM, Billaud M, Magaud JP and Corbo L. (1998). J. Biol. Chem., 273, 22563-22569.
151. Rubinstein LV, Shoemaker RH, Paull KD, Simon RM, Tosini S, Skehan P, Scudiero DA, Monks A and Boyd MR. (1990). J. Natl. Cancer Inst., 82, 1113-1118.
152. Sabbatini P, Lin J, Levine AJ and White E. (1995). Genes Dev., 9, 2184-2192.
153. Savitsky K, Bar-Shira A, Gilad S, Rotman G, Ziv Y, Vinagaite L, Tagle DA, Smith S, Uziel T, Sfez S, Ashkenazi M, Pecker I, Frydman M, Harnik R, Patanjali SR, Simmons A, Clines GA, Sartiel A, Gatti RA, Chessa L, Sanal O, Lavin MF, Jaspers NGJ, Malcom A, Taylor R, Arlett CF, Miki T, Weissman SM, Lovett M, Collins FS and Shiloh Y. (1995). Science, 268, 1749-1753.
154. Schena M, Shalon D, Davis RW and Brown PO. (1995). Science, 270, 467-470.
155. Schena M, Shalon D, Heller R, Chai A, Brown PO and Davis RW. (1996). Proc. Natl. Acad. Sci. USA, 93, 10614-10619.
156. Schlegel J, Peters I, Orrenius S, Miller DK, Thornberry NA, Yamin TT and Nicholson DW. (1996). J. Biol. Chem., 271, 1841-1844.
157. Schott AF, Apel IJ, Nunez G and Clarke MF. (1995). Oncogene, 11, 1389-1394.
158. Screaton GR, Mongkolsapaya J, Xu XN, Cowper AE, McMichael AJ and Bell JI. (1997). Curr. Biol., 7, 693-696.
159. Selivanova G, Iotsova V, Kiseleva E, Strom M, Bakalkin G, Grafstrom RC and Wiman KG. (1996). Nucleic Acids Res., 24, 3560-3567.
160. Selvakumaran M, Lin H-K, Miyashita T, Wang HG, Krajewski S, Reed JC, Hoffman B and Liebermann D. (1994). Oncogene, 9, 1791-1798.
161. Shafman T, Khanna KK, Kedar P, Spring K, Kozlov S, Yen T, Hobson K, Gatei M, Zhang N, Walters D, Egerton M, Shiloh Y, Kharbanda S, Kufe D and Lavin MF. (1997). Nature, 387, 520-523.
162. Sheikh MS, Burns TF, Huang Y, Wu GS, Amundson S, Brooks KS, Fornace Jr AJ and El-Deiry W.S. (1998). Cancer Res., in press.
163. Sherman ML, Datta R, Hallahan DE, Weichselbaum RR and Kufe DW. (1990). Proc. Natl. Acad. Sci. USA, 87, 5663-5666.
164. Smith ML, Chen IT, Zhan Q, O'Connor PM and Fornace Jr AJ. (1995). Oncogene, 10, 1053-1059.
165. Smith ML and Fornace Jr AJ. (1996). Am. J. Pathol., 148, 1019-1022.
166. Smith ML and Fornace AJJ. (1997). Proc. Natl. Acad. Sci. USA, 94, 12255-12257.
167. Somasundaram K, Zhang H, Zeng YX, Houvras Y, Peng Y, Zhang H, Wu GS, Licht JD, Weber BL and El-Deiry WS. (1997). Nature, 389, 187-190.
168. Stewart N, Hicks GG, Paraskevas F and Mowat M. (1995). Oncogene, 10, 109-115.
169. Stinson SF, Alley MC, Kopp WC, Fiebig HH, Mullendore LA, Pittman AF, Kenney S, Keller J and Boyd MR. (1992). Anticancer Res., 12, 1035-1053.
170. Stott FJ, Bates S, James MC, MeConnell BB, Starborg M, Brookes S, Palmero I, Ryan K, Hara E, Vousden KH and Peters G. (1998). EMBO J., 17, 5001-5014.
171. Sturzbecher HW, Brain R, Addison C, Rudge K, Remm M, Grimaldi M, Keenan E and Jenkins JR. (1992). Oncogene, 7, 1513-1523.
172. Symonds H, Krall L, Remington L, Saenz-Robles M, Lowe S, Jacks T and Van Dyke T. (1994). Cell, 78, 703-711.
173. Tewari M and Dixit VM. (1995). J. Biol. Chem., 270, 3255-3260.
174. Theis S and Roomer K. (1998). Oncogene, 17, 557-564.
175. Thomas A and White E. (1998). Genes Dev., 12, 1975-1985.
176. Thompson DA, Belinsky G, Chang THT, Jones DL, Schlegel R and Munger K. (1997). Oncogene, 15, 3025-3035.
177. Tokino T, Thiagalingam S, El-Deiry WS, Waldman T, Kinzler KW and Vogelstein B. (1994). Hum. Mol. Genet., 3, 1537-1542.
178. van Osdol WW, Myers TG, Paull KD, Kohn KW and Weinstein JN. (1994). J. Natl. Cancer Inst., 86, 1853-1859.
179. Velculescu VE, Zhang L, Vogelstein B and Kinzler KW. (1995). Science, 270, 484-487.
180. Wagner AJ, Kokontis JM and Hay N. (1994). Genes Dev., 8, 2817-2830.
181. Wahl GM, Linke SP, Paulson TG and Huang LC. (1997). Cancer Surv., 29, 183-219.
182. Walczak H, Degli-Esposti MA, Johnson RS, Smolak PJ, Waugh JY, Boiani N, Timour MS, Gerhart MJ, Schooley KA, Smith CA, Goodwin RG and Rauch CT. (1997). EMBO J., 16, 5386-5397.
183. Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA and O'Connor PM. (1996a). J. Natl. Cancer Inst., 88, 956-965.
184. Wang XW, Yeh H, Schaeffer L, Roy R, Moncollin V, Egly JM, Wang Z, Freidberg EC, Evans MK, Taffe BG, et al. (1995). Nat. Genet., 10, 188-195.
185. Wang XW, Vermeulen W, Coursen JD, Gibson M, Lupold SE, Forrester K, Xu G, Elmore L, Yeh H, Hoeijmakers JH and Harris CC. (1996b). Genes Dev., 10, 1219-1232.
186. Wang XW, Zhan Q, Coursen JD, Khan M, Kontny HU, O'Connor PM, Fornace Jr AJ and Harris CC. (1997). Proc. Amer. Assoc. Ca. Res., 38, 201.
187. Waterman MJ, Stavridi ES, Waterman JL and Halazonetis TD. (1998). Nat. Genet., 19, 175-178.
188. Weinstein JN, Kohn KW, Grever MR, Viswanadhan VN, Rubinstein LV, Monks AP, Scudiero DA, Welch L, Koutsoukos AD, Chiausa AJ and Paull KD. (1992). Science, 258, 447-451.
189. Weinstein JN, Myers TG, O'Connor PM, Friend SH, Fornace Jr AJ, Kohn KW, Fojo T, Bates SE, Rubinstein LV, Anderson NL, Buolamwini JK, Osdol, WW, Monks AP, Scudiero DA, Sausville EA, Zaharevitz DW, Bunow B, Johnson GS, Wittes RE and Paull KD. (1997). Science, 275, 343-349.
190. Wen ST, Jackson PK and Van Etten RA. (1996). EMBO J., 15, 1583-1595.
191. Westphal CH, Rowan S, Schmaltz C, Elson A, Fisher DE and Leder P. (1997). Nat. Genet., 16, 397-401.
192. White A, Livanos EM and Tlsty TD. (1994). Genes Dev., 8, 666-677.
193. Wolf D, Harris N and Rotter V. (1984). Cell, 38, 119-126.
194. Woo RA, McLure KG, Lees-Miller SP, Rancourt DE and Lee PW. (1998). Nature, 394, 700-704.
195. Wosikowski K, Schuurhuis D, Johnson K, Paull KD, Myers TG, Weinstein JN and Bates SE. (1997). J. Natl. Cancer Inst., 89, 1505-1515.
196. Wu GS, Burns TF, McDonald III ER, Jiang W, Meng R, Krantz ID, Kao G, Gan DD, Zhou JY, Muschel R, Hamilton SR, Spinner NB, Markowitz S, Wu G and El-Deiry WS. (1997). Nat. Genet., 17, 141-143.
197. Wu X and Levine AJ. (1994). Proc. Natl. Acad. Sci. USA, 91, 3602-3606.
198. Xu Y and Baltimore D. (1996). Genes Dev., 10, 2401-2410.
199. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A and Oren M. (1991). Nature, 352, 345-347.
200. Yuan ZM, Huang Y, Whang Y, Sawyers C, Weichselbaum R, Kharbanda S and Kufe D. (1996). Nature, 382, 272-274.
201. Zeng X, Levine AJ and Lu H. (1998). Proc. Natl. Acad. Sci. USA, 95, 6681-6686.
202. Zhan Q, Fan S, Bae I, Guillouf C, Liebermann DA, O'Connor PM and Fornace Jr AJ. (1994). Oncogene, 9, 3743-3751.
203. Zhan Q, Alamo Jr I, Yu K, Boise LH, O'Connor PM and Fornace Jr AJ. (1996a). Oncogene, 13, 2287-2293.
204. Zhan Q, Fan S, Smith ML, Bae I, Yu K, Alamo Jr I, O'Connor PM and Fornace Jr AJ. (1996b). DNA Cell Biol., 15, 805-815.
205. Zhan Q, Bae I, Fornace Jr AJ, and Craig RW. (1997). Oncogene, 14, 1031-1039.
206. Zhan Q, Antinore MJ, Wang XW, Carrier F, Harris CC and Fornace Jr AJ. (1998a). Oncogene, in press.
207. Zhan Q, Chen IT, Antinore MJ and Fornace Jr AJ. (1998b). Molec. Cell. Biol., 18, 2768-2778.
208. Zhang H, Somasundaram K, Peng Y, Tian H, Zhang H, Bi D, Weber BL and El-Deiry WS. (1998a). Oncogene, 16, 1713-1721.
209. Zhang Y, Xiong Y and Yarbrough WG. (1998b). Cell, 92, 725-734.
210. Ziegler A, Jonason AS, Leffell DJ, Simon JA, Sharma HW, Kimmelman J, Jacks T and Brash DE. (1994). Nature, 372, 773-776.
211. Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ and Roussel MF. (1998). Genes Dev., 12, 2424-2433.
212. Zuo Z, Dean NM and Honkanen RE. (1998). J. Biol. Chem., 273, 12250-12258.