메뉴 건너뛰기




Volumn 57, Issue 6, 1997, Pages 1171-1179

p53 mediates permanent arrest over multiple cell cycles in response to γ-irradiation

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

EID: 0030938259     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (149)

References (73)
  • 1
    • 0027298576 scopus 로고
    • Induction of cellular p53 activity by DNA-damaging agents and growth arrest
    • Zhan, Q., Carrier, F., and Fornace, A. J. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol. Cell. Biol., 13: 4242-50, 1993.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4242-4250
    • Zhan, Q.1    Carrier, F.2    Fornace, A.J.3
  • 2
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone. L. R., White, A., Sprouse, J., Livanos, E., Jacks, T., and Tlsty, T. D. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell, 70: 923-935, 1992.
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, L.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tlsty, T.D.6
  • 3
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • Yin, Y., Tainsky, M. A., Bischoff, F. Z., Strong, L. C., and Wahl, G. M. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell, 70: 937-948, 1992.
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin, Y.1    Tainsky, M.A.2    Bischoff, F.Z.3    Strong, L.C.4    Wahl, G.M.5
  • 4
    • 0027319521 scopus 로고
    • P53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe, S. W., Schmitt, E. M., Smith, S. W., Osborne, B. A., and Jacks, T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature (Lond.), 362: 847-849, 1993.
    • (1993) Nature (Lond.) , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 5
  • 7
    • 0029964158 scopus 로고    scopus 로고
    • A reversible, p53-dependent GO/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage
    • Linke, S. P., Clarkin, K. C., Di, L. A., Tsou, A., and Wahl, G. M. A reversible, p53-dependent GO/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes Dev., 10: 934-947, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 934-947
    • Linke, S.P.1    Clarkin, K.C.2    Di, L.A.3    Tsou, A.4    Wahl, G.M.5
  • 10
    • 0029029741 scopus 로고
    • Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcriptioncoupled repair and enhanced UV resistance
    • Ford, J. M., and Hanawalt, P. C. Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcriptioncoupled repair and enhanced UV resistance. Proc, Natl. Acad. Sci. USA, 92: 8876-8880, 1995.
    • (1995) Proc, Natl. Acad. Sci. USA , vol.92 , pp. 8876-8880
    • Ford, J.M.1    Hanawalt, P.C.2
  • 12
    • 0028919069 scopus 로고
    • Involvement of the p53 tumor suppressor in repair of U.V.-type DNA damage
    • Smith. M. L., Chen, I. T., Zhan, Q., O'Connor, P. M., and Fornace, A. J. Involvement of the p53 tumor suppressor in repair of U.V.-type DNA damage. Oncogene, 10: 1053-1059, 1995.
    • (1995) Oncogene , vol.10 , pp. 1053-1059
    • Smith, M.L.1    Chen, I.T.2    Zhan, Q.3    O'Connor, P.M.4    Fornace, A.J.5
  • 15
    • 0028813528 scopus 로고
    • Evidence for a second cell cycle block at G2/M by p53
    • Stewart, N., Hicks. G. G., Paraskevas, F., and Mowat, M. Evidence for a second cell cycle block at G2/M by p53. Oncogene, 10: 109-115, 1995.
    • (1995) Oncogene , vol.10 , pp. 109-115
    • Stewart, N.1    Hicks, G.G.2    Paraskevas, F.3    Mowat, M.4
  • 16
    • 0028980494 scopus 로고
    • P53 controls both the G2/M and the Gl cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts
    • Agarwal, M. L., Agarwal, A., Taylor, W. R., and Stark, G. R. p53 controls both the G2/M and the Gl cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. Proc. Natl. Acad. Sci. USA, 92: 8493-8497, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8493-8497
    • Agarwal, M.L.1    Agarwal, A.2    Taylor, W.R.3    Stark, G.R.4
  • 17
    • 0023712476 scopus 로고
    • The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae
    • Weinert, T. A., and Hartwell, L. H. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science (Washington DC), 247: 317-322, 1988.
    • (1988) Science (Washington DC) , vol.247 , pp. 317-322
    • Weinert, T.A.1    Hartwell, L.H.2
  • 18
    • 0027109075 scopus 로고
    • Cancer. p53, guardian of the genome
    • Lane, D. P. Cancer. p53, guardian of the genome. Nature (Lond.), 358: 15-16, 1992.
    • (1992) Nature (Lond.) , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 19
    • 0023757362 scopus 로고
    • I Comparative human cellular radiosensitivity. I. the effect of SV40 transformation 1 and immortalisation on the γ-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes
    • Arlett, C. F., Green, M. H., Priestley, A., Harcourt, S. A., and Mayne, L. V. i Comparative human cellular radiosensitivity. I. The effect of SV40 transformation 1 and immortalisation on the γ-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes. Int. J. Radiat. Biol., 54: 911-928, 1988.
    • (1988) Int. J. Radiat. Biol. , vol.54 , pp. 911-928
    • Arlett, C.F.1    Green, M.H.2    Priestley, A.3    Harcourt, S.A.4    Mayne, L.V.5
  • 20
    • 0026671086 scopus 로고
    • Transformation and radiosensitivity of human diploid skin J fibroblasts transfected with SV40 T-antigen mutants defective in RB and P53 binding 1 domains
    • Su, L. N., and Little, J. B. Transformation and radiosensitivity of human diploid skin J fibroblasts transfected with SV40 T-antigen mutants defective in RB and P53 binding 1 domains. Int. J, Radiat. Biol., 62: 461-468, 1992.
    • (1992) Int. J, Radiat. Biol. , vol.62 , pp. 461-468
    • Su, L.N.1    Little, J.B.2
  • 21
    • 0030023848 scopus 로고    scopus 로고
    • Cell cycle synchrony unmasks the influence of p53 function on radiosensitivity of human glioblastoma cells
    • Yount, G. L., Haas, K. D., Vidair, C. A., Haas, M., Dewey, W. C., and Israel, M. A. Cell cycle synchrony unmasks the influence of p53 function on radiosensitivity of human glioblastoma cells. Cancer Res., 56: 500-506, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 500-506
    • Yount, G.L.1    Haas, K.D.2    Vidair, C.A.3    Haas, M.4    Dewey, W.C.5    Israel, M.A.6
  • 22
    • 0029054581 scopus 로고
    • Abrogation of p53 function by transfection of HPV16 E6 gene enhances the resistance of human diploid fibroblasts to ionizing radiation
    • Tsang, N. M., Nagasawa, H., Li, C., and Little, J. B. Abrogation of p53 function by transfection of HPV16 E6 gene enhances the resistance of human diploid fibroblasts to ionizing radiation. Oncogene, 10: 2403-2408, 1995.
    • (1995) Oncogene , vol.10 , pp. 2403-2408
    • Tsang, N.M.1    Nagasawa, H.2    Li, C.3    Little, J.B.4
  • 23
    • 0027285380 scopus 로고
    • P53 mutations increase resistance to ionizing radiation
    • Lee, J. M., and Bernstein, A. p53 mutations increase resistance to ionizing radiation. Proc. Natl. Acad. Sci. USA, 90: 5742-5746, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5742-5746
    • Lee, J.M.1    Bernstein, A.2
  • 24
    • 0027931008 scopus 로고
    • Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity
    • McIlwrath, A. J., Vasey, P. A., Ross, G. M., and Brown, R. Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity. Cancer Res., 54: 3718-3722, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3718-3722
    • McIlwrath, A.J.1    Vasey, P.A.2    Ross, G.M.3    Brown, R.4
  • 26
    • 0028932603 scopus 로고
    • Cell cycle regulation in response to DNA damage in mammalian cells: A historical perspective
    • Murnane, J. P. Cell cycle regulation in response to DNA damage in mammalian cells: a historical perspective. Cancer Metastasis Rev., 14: 17-29, 1995.
    • (1995) Cancer Metastasis Rev. , vol.14 , pp. 17-29
    • Murnane, J.P.1
  • 27
    • 0027893001 scopus 로고
    • Loss of a p53-associated Gl checkpoint does not decrease cell survival following DNA damage
    • Slichenmyer, W. J., Nelson, W. G., Slebos, R. J., and Kastan, M. B. Loss of a p53-associated Gl checkpoint does not decrease cell survival following DNA damage. Cancer Res., 53: 4164-4168, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 4164-4168
    • Slichenmyer, W.J.1    Nelson, W.G.2    Slebos, R.J.3    Kastan, M.B.4
  • 28
    • 0028033027 scopus 로고
    • Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53 deficient mice
    • Lee, J. M., Abrahamson, J. L., Kandel, R., Donehower, L. A., and Bernstein, A. Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53 deficient mice. Oncogene, 9: 3731-3736, 1994.
    • (1994) Oncogene , vol.9 , pp. 3731-3736
    • Lee, J.M.1    Abrahamson, J.L.2    Kandel, R.3    Donehower, L.A.4    Bernstein, A.5
  • 29
    • 0029099361 scopus 로고
    • Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice
    • Bouffler, S. D., Kemp, C. J., Balmain, A., and Cox, R. Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice. Cancer Res., 55: 3883-3889, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3883-3889
    • Bouffler, S.D.1    Kemp, C.J.2    Balmain, A.3    Cox, R.4
  • 31
    • 0029156729 scopus 로고
    • P53 wild-type and p53 nullizygous Big Blue transgenic mice have similar frequencies and patterns of observed mutation in liver, spleen and brain
    • Nishino, H., Knoll, A., Buettner, V. L., Frisk, C. S., Manila, Y., Haavik, J., and Sommer, S. S. p53 wild-type and p53 nullizygous Big Blue transgenic mice have similar frequencies and patterns of observed mutation in liver, spleen and brain. Oncogene, 11: 263-270, 1995.
    • (1995) Oncogene , vol.11 , pp. 263-270
    • Nishino, H.1    Knoll, A.2    Buettner, V.L.3    Frisk, C.S.4    Manila, Y.5    Haavik, J.6    Sommer, S.S.7
  • 32
    • 0029029938 scopus 로고
    • P53 inactivation by HPV16 E6 results in increased mutagenesis in human cells
    • Havre, P. A., Yuan, J., Hedrick, L., Cho, K. R., and Glazer, P. M. p53 inactivation by HPV16 E6 results in increased mutagenesis in human cells. Cancer Res., 55: 4420-4424, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 4420-4424
    • Havre, P.A.1    Yuan, J.2    Hedrick, L.3    Cho, K.R.4    Glazer, P.M.5
  • 33
    • 0029014496 scopus 로고
    • Requirement for tyrosine phosphorylation of Cdk4 in Gl arrest induced by ultraviolet irradiation
    • Terada, Y., Tatsuka, M., Jinno, S., and Okayama, H. Requirement for tyrosine phosphorylation of Cdk4 in Gl arrest induced by ultraviolet irradiation. Nature (Lond.), 376: 358-362, 1995.
    • (1995) Nature (Lond.) , vol.376 , pp. 358-362
    • Terada, Y.1    Tatsuka, M.2    Jinno, S.3    Okayama, H.4
  • 34
    • 0027970713 scopus 로고
    • DNA damage triggers a prolonged p53-dependent Gl arrest and long-term induction of Cipl in normal human fibroblasts
    • Di Leonardo, A., Linke, S. P., Clarkin, K., and Wahl, G. M. DNA damage triggers a prolonged p53-dependent Gl arrest and long-term induction of Cipl in normal human fibroblasts. Genes Dev., 8: 2540-2551, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 2540-2551
    • Di Leonardo, A.1    Linke, S.P.2    Clarkin, K.3    Wahl, G.M.4
  • 35
    • 0028969514 scopus 로고
    • Genetic instability as a consequence of inappropriate entry and progression through S-phase
    • Almasan. A., Linke, S., Paulson, T., Huang, L-c., and Wahl, G. Genetic instability as a consequence of inappropriate entry and progression through S-phase. Cancer Metastasis Rev., 14: 59-73, 1995.
    • (1995) Cancer Metastasis Rev. , vol.14 , pp. 59-73
    • Almasan, A.1    Linke, S.2    Paulson, T.3    Huang, L.-C.4    Wahl, G.5
  • 36
    • 0028342664 scopus 로고
    • Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
    • Noda, A., Ning, Y., Venable, S. F., Pereira-Smith, O. M., and Smith, J. R. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res., 211: 90-98, 1994.
    • (1994) Exp. Cell Res. , vol.211 , pp. 90-98
    • Noda, A.1    Ning, Y.2    Venable, S.F.3    Pereira-Smith, O.M.4    Smith, J.R.5
  • 37
    • 0028942024 scopus 로고
    • Radiation-induced irreversible G(0)/G(1) block is abolished in human diploid fibroblasts transfected with the human papilloma virus E6 gene: Implication of the p53-Cipl/WAFl pathway
    • Li, C. Y., Nagasawa, H., Tsang, N. M., and Little, J. B. Radiation-induced irreversible G(0)/G(1) block is abolished in human diploid fibroblasts transfected with the human papilloma virus E6 gene: implication of the p53-Cipl/WAFl pathway. Int. J. Oncol., 6: 233-236, 1995.
    • (1995) Int. J. Oncol. , vol.6 , pp. 233-236
    • Li, C.Y.1    Nagasawa, H.2    Tsang, N.M.3    Little, J.B.4
  • 38
    • 0021195862 scopus 로고
    • The effect of X irradiation on the progression of mouse 10T1/2 cells released from density-inhibited cultures
    • Nagasawa, H., Robertson, J. B., Arundel, C. S., and Little. J. B. The effect of X irradiation on the progression of mouse 10T1/2 cells released from density-inhibited cultures. Radiat. Res., 97: 537-545, 1984.
    • (1984) Radiat. Res. , vol.97 , pp. 537-545
    • Nagasawa, H.1    Robertson, J.B.2    Arundel, C.S.3    Little, J.B.4
  • 39
    • 0020587099 scopus 로고
    • Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts
    • Nagasawa, H., and Little, J. B. Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts. Mutat. Res., 709: 297-308, 1983.
    • (1983) Mutat. Res. , vol.709 , pp. 297-308
    • Nagasawa, H.1    Little, J.B.2
  • 40
    • 0026609366 scopus 로고
    • The E6 and E7 genes of human : Papillomavirus type 6 have weak immortalizing activity in human epithelial cells
    • Halben, C. L., Demers, G. W., and Galloway. D. A. The E6 and E7 genes of human : papillomavirus type 6 have weak immortalizing activity in human epithelial cells. ] J. Virol., 66: 2125-2134, 1992.
    • (1992) J. Virol. , vol.66 , pp. 2125-2134
    • Halben, C.L.1    Demers, G.W.2    Galloway, D.A.3
  • 41
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner, M., Wemess, B. A., Huibregtse, J. M., Levine, A. J., and Howley, P. M. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell, 63: 1129-1136, 1990.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Wemess, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 42
    • 0028986606 scopus 로고
    • Relationship between radiation-induced G1 phase arrest and p53 function in human tumor cells
    • Nagasawa, H., Li, C. Y., Maki, C, G., Imrich, A. C., and Little, J. B. Relationship between radiation-induced G1 phase arrest and p53 function in human tumor cells. Cancer Res., 55: 1842-1846, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 1842-1846
    • Nagasawa, H.1    Li, C.Y.2    Maki, C.G.3    Imrich, A.C.4    Little, J.B.5
  • 43
    • 0029278864 scopus 로고
    • Elevated levels of wild-type p53 induced by radiolabeling of cells leads to apoptosis or sustained growth arrest
    • Yeargin, J., and Haas, M. Elevated levels of wild-type p53 induced by radiolabeling of cells leads to apoptosis or sustained growth arrest. Curr. Biol., 5: 423-431, 1995.
    • (1995) Curr. Biol. , vol.5 , pp. 423-431
    • Yeargin, J.1    Haas, M.2
  • 44
    • 0028174531 scopus 로고
    • P53 expression in cultured cells following radioisotope labelling
    • Dover, R., Jayaram, Y., Patel, K., and Chinery, R. p53 expression in cultured cells [following radioisotope labelling. J. Cell Sci., 107:1181-1184, 1994.
    • (1994) J. Cell Sci. , vol.107 , pp. 1181-1184
    • Dover, R.1    Jayaram, Y.2    Patel, K.3    Chinery, R.4
  • 45
    • 0023841617 scopus 로고
    • BrdU; Hoechst flow cytometry: A unique tool for quantitative cell cycle analysis
    • Rabinovitch, P. S., Kubbies, M., Chen, Y. C., Schindler. D., and Hoehn. H. BrdU; Hoechst flow cytometry: a unique tool for quantitative cell cycle analysis. Exp. Cell Res., 174: 309-318, 1988.
    • (1988) Exp. Cell Res. , vol.174 , pp. 309-318
    • Rabinovitch, P.S.1    Kubbies, M.2    Chen, Y.C.3    Schindler, D.4    Hoehn, H.5
  • 46
    • 0028153332 scopus 로고
    • Failla Memorial Lecture. Changing views of cellular radiosensitivity
    • Little, J. B. Failla Memorial Lecture. Changing views of cellular radiosensitivity. Radiat. Res., 140: 299-311, 1994.
    • (1994) Radiat. Res. , vol.140 , pp. 299-311
    • Little, J.B.1
  • 47
    • 0028978183 scopus 로고
    • CIPI/WAFI undergo normal development but are defective in Gl checkpoint control
    • CIPI/WAFI undergo normal development but are defective in Gl checkpoint control. Cell, 82: 675-684, 1995.
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 49
    • 0028827582 scopus 로고
    • Diminished capacity for p53 in mediating a radiation-induced Gl arrest in established human tumor cell lines
    • Li, C. Y., Nagasawa, H., Dahlberg, W. K., and Little, J. B. Diminished capacity for p53 in mediating a radiation-induced Gl arrest in established human tumor cell lines. Oncogene, 11: 1885-1892, 1995.
    • (1995) Oncogene , vol.11 , pp. 1885-1892
    • Li, C.Y.1    Nagasawa, H.2    Dahlberg, W.K.3    Little, J.B.4
  • 50
    • 0014688062 scopus 로고
    • Repair of sub-lethal and potentially lethal radiation damage in plateau phase cultures of human cells
    • Little, J. B. Repair of sub-lethal and potentially lethal radiation damage in plateau phase cultures of human cells. Nature (Lond.), 224: 804-806, 1969.
    • (1969) Nature (Lond.) , vol.224 , pp. 804-806
    • Little, J.B.1
  • 51
    • 0021997077 scopus 로고
    • Effect of confluent holding on potentially lethal damage repair, cell cycle progression, and chromosomal aberrations in human normal and ataxia-telangiectasia fibroblasts
    • Little, J. B., and Nagasawa, H. Effect of confluent holding on potentially lethal damage repair, cell cycle progression, and chromosomal aberrations in human normal and ataxia-telangiectasia fibroblasts. Radiat. Res., 101: 81-93, 1985.
    • (1985) Radiat. Res. , vol.101 , pp. 81-93
    • Little, J.B.1    Nagasawa, H.2
  • 52
    • 0024195429 scopus 로고
    • DNA damage produced by ionizing radiation in mammalian cells: Identities, mechanisms of formation, and reparability
    • Ward, J. F. DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. Prog. Nucleic Acid Res. Mol. Biol., 35; 95-125, 1988.
    • (1988) Prog. Nucleic Acid Res. Mol. Biol. , vol.35 , pp. 95-125
    • Ward, J.F.1
  • 53
    • 0021348925 scopus 로고
    • Kinetics and extent of repair of bleomycin-induced chromosome damage in quiescent normal human fibroblasts and human mononuclear blood cells
    • Sen, P., and Hittelman, W. N. Kinetics and extent of repair of bleomycin-induced chromosome damage in quiescent normal human fibroblasts and human mononuclear blood cells. Cancer Res., 44: 591-596, 1984.
    • (1984) Cancer Res. , vol.44 , pp. 591-596
    • Sen, P.1    Hittelman, W.N.2
  • 54
    • 0026733077 scopus 로고
    • The contribution of DNA and chromosome repair deficiencies to the radiosensitivity of ataxia-telangiectasia
    • Pandita. T. K., and Hittelman, W. N. The contribution of DNA and chromosome repair deficiencies to the radiosensitivity of ataxia-telangiectasia. Radiat. Res., 131: 214-223, 1992.
    • (1992) Radiat. Res. , vol.131 , pp. 214-223
    • Pandita, T.K.1    Hittelman, W.N.2
  • 55
    • 0024419461 scopus 로고
    • Association among DNA/chromosome break rejoining rates, chromatin structure alterations, and radiation sensitivity in human tumor cell lines
    • Schwartz, J. L., and Vaughan, A. T. Association among DNA/chromosome break rejoining rates, chromatin structure alterations, and radiation sensitivity in human tumor cell lines. Cancer Res., 49: 5054-5057, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 5054-5057
    • Schwartz, J.L.1    Vaughan, A.T.2
  • 56
    • 0023252949 scopus 로고
    • A quantitative comparison of potentially lethal damage repair and the rejoining of interphase chromosome breaks in low passage normal human fibroblasts
    • Cornforth, M. N., and Bedford, J. S. A quantitative comparison of potentially lethal damage repair and the rejoining of interphase chromosome breaks in low passage normal human fibroblasts. Radiat. Res., III: 385-405, 1987.
    • (1987) Radiat. Res. , vol.3 , pp. 385-405
    • Cornforth, M.N.1    Bedford, J.S.2
  • 57
    • 0019413225 scopus 로고
    • Some biochemical consequences of the spatial distribution of ionizing radiation-produced free radicals
    • Ward, J. F. Some biochemical consequences of the spatial distribution of ionizing radiation-produced free radicals. Radiat. Res., 86: 185-195, 1981.
    • (1981) Radiat. Res. , vol.86 , pp. 185-195
    • Ward, J.F.1
  • 58
    • 0027421043 scopus 로고
    • Loss of a yeast telomere: Arrest, recovery, and chromosome loss
    • Sandell, L. L., and Zakian, V. A. Loss of a yeast telomere: arrest, recovery, and chromosome loss. Cell, 75: 729-739, 1993.
    • (1993) Cell , vol.75 , pp. 729-739
    • Sandell, L.L.1    Zakian, V.A.2
  • 59
    • 0027285362 scopus 로고
    • Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid
    • Bennett, C. B., Lewis, A. L., Baldwin, K. K., and Resnick, M. A. Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid. Proc. Natl. Acad. Sci. USA, 90: 5613-5617, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5613-5617
    • Bennett, C.B.1    Lewis, A.L.2    Baldwin, K.K.3    Resnick, M.A.4
  • 60
    • 0017239995 scopus 로고
    • DNA strand breaks, repair, and survival in X-irradiated mammalian cells
    • Dugle, D. L., Gillespie, C. J., and Chapman, J. D. DNA strand breaks, repair, and survival in X-irradiated mammalian cells. Proc. Natl, Acad. Sci. USA, 73: 809-812, 1976.
    • (1976) Proc. Natl, Acad. Sci. USA , vol.73 , pp. 809-812
    • Dugle, D.L.1    Gillespie, C.J.2    Chapman, J.D.3
  • 61
    • 0014950080 scopus 로고
    • Double-strand breaks in the DNA of a mammalian cell after X-irradiation
    • Lehmann, A. R., and Ormerod. M. G. Double-strand breaks in the DNA of a mammalian cell after X-irradiation. Biochim. Biophys. Acta, 2/7: 268-277, 1970.
    • (1970) Biochim. Biophys. Acta , vol.2-7 , pp. 268-277
    • Lehmann, A.R.1    Ormerod, M.G.2
  • 62
    • 0029897210 scopus 로고    scopus 로고
    • Sensitivity and selectivity of the p53-mediated DNA damage sensor
    • Huang, L-c., Clarkin, K. C., and Wahl, G. M. Sensitivity and selectivity of the p53-mediated DNA damage sensor. Proc. Natl. Acad. Sci. USA, 93: 4827-4832, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4827-4832
    • Huang, L.-C.1    Clarkin, K.C.2    Wahl, G.M.3
  • 63
    • 0028938734 scopus 로고
    • P53-dependent growth arrest of REF52 cells containing newly amplified DNA
    • Ishizaka, Y., Chernov, M. V., Bums, C. M, and Stark, G. R. p53-dependent growth arrest of REF52 cells containing newly amplified DNA. Proc. Natl. Acad. Sci. USA, 92: 3224-3228, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3224-3228
    • Ishizaka, Y.1    Chernov, M.V.2    Bums, C.M.3    Stark, G.R.4
  • 64
    • 0242672936 scopus 로고
    • Molecular dissection of mammalian gene amplification: New mechanistic insights revealed by analyses of very early events
    • Windle, B. E., and Wahl, G. M. Molecular dissection of mammalian gene amplification: new mechanistic insights revealed by analyses of very early events. Mutat. Res., 276: 199-224, 1992.
    • (1992) Mutat. Res. , vol.276 , pp. 199-224
    • Windle, B.E.1    Wahl, G.M.2
  • 65
    • 0026018901 scopus 로고
    • A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration
    • Windle, B., Draper, B. W., Yin, Y. X., O'Gorman, S., and Wahl, G. M. A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration. Genes Dev., 5: 160-174, 1991.
    • (1991) Genes Dev. , vol.5 , pp. 160-174
    • Windle, B.1    Draper, B.W.2    Yin, Y.X.3    O'Gorman, S.4    Wahl, G.M.5
  • 66
    • 0029945097 scopus 로고    scopus 로고
    • A double-strand break within a yeast artificial chromosome (YAC) containing human DNA can result in YAC loss, deletion, or cell lethality
    • Bennett, C. B., Westmoreland, T. J., Snipe, J. R., and Resnick, M. A. A double-strand break within a yeast artificial chromosome (YAC) containing human DNA can result in YAC loss, deletion, or cell lethality. Mol. Cell. Biol., 16: 4414-4425, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4414-4425
    • Bennett, C.B.1    Westmoreland, T.J.2    Snipe, J.R.3    Resnick, M.A.4
  • 67
    • 0028269782 scopus 로고
    • Ionizing radiation and cell cycle progression in ataxia telangiectasia
    • Beamish, H., Khanna, K. K., and Lavin, M. F. Ionizing radiation and cell cycle progression in ataxia telangiectasia. Radiat. Res., S130-S133, 1994.
    • (1994) Radiat. Res.
    • Beamish, H.1    Khanna, K.K.2    Lavin, M.F.3
  • 68
    • 0018881928 scopus 로고
    • Relationship of DNA repair to chromosome aberrations, sister-chromatid exchanges and survival during liquidholding recovery in X-irradiated mammalian cells
    • Fomace, A. J., Nagasawa, H., and Little, J. B. Relationship of DNA repair to chromosome aberrations, sister-chromatid exchanges and survival during liquidholding recovery in X-irradiated mammalian cells. Mutat. Res., 70: 323-336, 1980.
    • (1980) Mutat. Res. , vol.70 , pp. 323-336
    • Fomace, A.J.1    Nagasawa, H.2    Little, J.B.3
  • 69
    • 0023242252 scopus 로고
    • Relationship between the recovery from sublethal X-ray damage and the rejoining of chromosome breaks in normal human fibroblasts
    • Bedford, J. S., and Cornforth, M. N. Relationship between the recovery from sublethal X-ray damage and the rejoining of chromosome breaks in normal human fibroblasts. Radiat. Res., 111: 406-423, 1987.
    • (1987) Radiat. Res. , vol.111 , pp. 406-423
    • Bedford, J.S.1    Cornforth, M.N.2
  • 70
    • 0023937944 scopus 로고
    • Radiation-induced potentially lethal damage: DNA lesions susceptible to fixation
    • Iliakis, G. Radiation-induced potentially lethal damage: DNA lesions susceptible to fixation. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med, 53: 541-584, 1988.
    • (1988) Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med , vol.53 , pp. 541-584
    • Iliakis, G.1
  • 71
    • 0023744051 scopus 로고
    • Survival of human diploid skin fibroblasts from normal individuals after X-irradiation
    • Little, J. B., Nove, J., Strong, L. C., and Nichols, W. W. Survival of human diploid skin fibroblasts from normal individuals after X-irradiation. Int. J. Radiat. Biol., 54: 899-910, 1988.
    • (1988) Int. J. Radiat. Biol. , vol.54 , pp. 899-910
    • Little, J.B.1    Nove, J.2    Strong, L.C.3    Nichols, W.W.4
  • 72
    • 0026643180 scopus 로고
    • Delayed reproductive death as a dominant phenotype in cell clones surviving X-irradiation
    • Chang, W. P., and Little, J. B. Delayed reproductive death as a dominant phenotype in cell clones surviving X-irradiation. Carcinogenesis (Lond.), 13: 923-928, 1992.
    • (1992) Carcinogenesis (Lond.) , vol.13 , pp. 923-928
    • Chang, W.P.1    Little, J.B.2
  • 73
    • 0029874308 scopus 로고    scopus 로고
    • P53-dependent apoptosis suppresses radiation-induced teratogenesis
    • Norimura, T., Nomoto, S., Katsuki, M., Gondo, Y., and Kondo. S. p53-dependent apoptosis suppresses radiation-induced teratogenesis. Nat. Med., 2: 577-580, 1996.
    • (1996) Nat. Med. , vol.2 , pp. 577-580
    • Norimura, T.1    Nomoto, S.2    Katsuki, M.3    Gondo, Y.4    Kondo, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.