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Volumn 5, Issue , 2016, Pages

Dietary metabolites and the gut microbiota: An alternative approach to control inflammatory and autoimmune diseases

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; HISTONE DEACETYLASE; PREBIOTIC AGENT; PROBIOTIC AGENT; SHORT CHAIN FATTY ACID;

EID: 85074159611     PISSN: None     EISSN: 20500068     Source Type: Journal    
DOI: 10.1038/cti.2016.29     Document Type: Review
Times cited : (205)

References (126)
  • 1
    • 84902657771 scopus 로고    scopus 로고
    • Diet, metabolites, and "western-lifestyle" inflammatory diseases
    • Thorburn AN, Macia L, Mackay CR. Diet, metabolites, and "western-lifestyle" inflammatory diseases. Immunity 2014; 40: 833-842.
    • (2014) Immunity , vol.40 , pp. 833-842
    • Thorburn, A.N.1    Macia, L.2    MacKay, C.R.3
  • 2
    • 84860260510 scopus 로고    scopus 로고
    • Trends in dietary fiber intake in the United States, 1999-2008
    • King DE, Mainous AG 3rd, Lambourne CA. Trends in dietary fiber intake in the United States, 1999-2008. J Acad Nutr Diet 2012; 112: 642-648.
    • (2012) J Acad Nutr Diet , vol.112 , pp. 642-648
    • King, D.E.1    Mainous, A.G.2    Lambourne, C.A.3
  • 3
    • 0038399801 scopus 로고    scopus 로고
    • Overweight and obesity in Australia: The 1999-2000 Australian Diabetes, Obesity and Lifestyle Study (AusDiab)
    • Cameron AJ, Welborn TA, Zimmet PZ, Dunstan DW, Owen N, Salmon J et al. Overweight and obesity in Australia: the 1999-2000 Australian Diabetes, Obesity and Lifestyle Study (AusDiab). Med J Aust 2003; 178: 427-432.
    • (2003) Med J Aust , vol.178 , pp. 427-432
    • Cameron, A.J.1    Welborn, T.A.2    Zimmet, P.Z.3    Dunstan, D.W.4    Owen, N.5    Salmon, J.6
  • 4
    • 0037373840 scopus 로고    scopus 로고
    • Health-related quality of life in Australian adults with renal insufficiency: A population-based study
    • Chow FY, Briganti EM, Kerr PG, Chadban SJ, Zimmet PZ, Atkins RC. Health-related quality of life in Australian adults with renal insufficiency: a population-based study. Am J Kidney Dis 2003; 41: 596-604.
    • (2003) Am J Kidney Dis , vol.41 , pp. 596-604
    • Chow, F.Y.1    Briganti, E.M.2    Kerr, P.G.3    Chadban, S.J.4    Zimmet, P.Z.5    Atkins, R.C.6
  • 5
    • 14844299867 scopus 로고    scopus 로고
    • A six-fold gradient in the incidence of type 1 diabetes at the eastern border of Finland
    • Kondrashova A, Reunanen A, Romanov A, Karvonen A, Viskari H, Vesikari T et al. A six-fold gradient in the incidence of type 1 diabetes at the eastern border of Finland. Ann Med 2005; 37: 67-72.
    • (2005) Ann Med , vol.37 , pp. 67-72
    • Kondrashova, A.1    Reunanen, A.2    Romanov, A.3    Karvonen, A.4    Viskari, H.5    Vesikari, T.6
  • 6
    • 0037364022 scopus 로고    scopus 로고
    • The prevention of type 2 diabetes-lifestyle change or pharmacotherapy? A challenge for the 21st century
    • Simpson RW, Shaw JE, Zimmet PZ. The prevention of type 2 diabetes-lifestyle change or pharmacotherapy? A challenge for the 21st century. Diabet Res Clin Prac 2003; 59: 165-180.
    • (2003) Diabet Res Clin Prac , vol.59 , pp. 165-180
    • Simpson, R.W.1    Shaw, J.E.2    Zimmet, P.Z.3
  • 8
    • 77957075815 scopus 로고    scopus 로고
    • Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
    • De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, Massart S et al. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci USA 2010; 107: 14691-14696.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14691-14696
    • De Filippo, C.1    Cavalieri, D.2    Di Paola, M.3    Ramazzotti, M.4    Poullet, J.B.5    Massart, S.6
  • 9
    • 83655193494 scopus 로고    scopus 로고
    • Microbial influences on epithelial integrity and immune function as a basis for inflammatory diseases
    • Macia L, Thorburn AN, Binge LC, Marino E, Rogers KE, Maslowski KM et al. Microbial influences on epithelial integrity and immune function as a basis for inflammatory diseases. Immunol Rev 2012; 245: 164-176.
    • (2012) Immunol Rev , vol.245 , pp. 164-176
    • Macia, L.1    Thorburn, A.N.2    Binge, L.C.3    Marino, E.4    Rogers, K.E.5    Maslowski, K.M.6
  • 11
    • 38749102702 scopus 로고    scopus 로고
    • Gluten-free but also gluten-enriched (gluten+) diet prevent diabetes in NOD mice; The gluten enigma in type 1 diabetes
    • Funda DP, Kaas A, Tlaskalova-Hogenova H, Buschard K. Gluten-free but also gluten-enriched (gluten+) diet prevent diabetes in NOD mice; the gluten enigma in type 1 diabetes. Diabetes Metab Res Rev 2008; 24: 59-63.
    • (2008) Diabetes Metab Res Rev , vol.24 , pp. 59-63
    • Funda, D.P.1    Kaas, A.2    Tlaskalova-Hogenova, H.3    Buschard, K.4
  • 12
    • 84933673955 scopus 로고    scopus 로고
    • Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease
    • Lerner A, Matthias T. Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease. Autoimmun Rev 2015; 14: 479-489.
    • (2015) Autoimmun Rev , vol.14 , pp. 479-489
    • Lerner, A.1    Matthias, T.2
  • 13
    • 84924301510 scopus 로고    scopus 로고
    • Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
    • Chassaing B, Koren O, Goodrich JK, Poole AC, Srinivasan S, Ley RE et al. Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome. Nature 2015; 519: 92-96.
    • (2015) Nature , vol.519 , pp. 92-96
    • Chassaing, B.1    Koren, O.2    Goodrich, J.K.3    Poole, A.C.4    Srinivasan, S.5    Ley, R.E.6
  • 15
    • 84858376593 scopus 로고    scopus 로고
    • The impact of the gut microbiota on human health: An integrative view
    • Clemente JC, Ursell LK, Parfrey LW, Knight R. The impact of the gut microbiota on human health: an integrative view. Cell 2012; 148: 1258-1270.
    • (2012) Cell , vol.148 , pp. 1258-1270
    • Clemente, J.C.1    Ursell, L.K.2    Parfrey, L.W.3    Knight, R.4
  • 18
  • 19
    • 84864614787 scopus 로고    scopus 로고
    • Host remodeling of the gut microbiome and metabolic changes during pregnancy
    • Koren O, Goodrich JK, Cullender TC, Spor A, Laitinen K, Backhed HK et al. Host remodeling of the gut microbiome and metabolic changes during pregnancy. Cell 2012; 150: 470-480.
    • (2012) Cell , vol.150 , pp. 470-480
    • Koren, O.1    Goodrich, J.K.2    Cullender, T.C.3    Spor, A.4    Laitinen, K.5    Backhed, H.K.6
  • 22
    • 0034959553 scopus 로고    scopus 로고
    • Short-chain fatty acids and human colonic function: Roles of resistant starch and nonstarch polysaccharides
    • Topping DL, Clifton PM. Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol Rev 2001; 81: 1031-1064.
    • (2001) Physiol Rev , vol.81 , pp. 1031-1064
    • Topping, D.L.1    Clifton, P.M.2
  • 24
    • 77949886724 scopus 로고    scopus 로고
    • Intestinal dysbiosis and reduced immunoglobulin-coated bacteria associated with coeliac disease in children
    • De Palma G, Nadal I, Medina M, Donat E, Ribes-Koninckx C, Calabuig M et al. Intestinal dysbiosis and reduced immunoglobulin-coated bacteria associated with coeliac disease in children. BMC Microbiol 2010; 10: 63.
    • (2010) BMC Microbiol , vol.10 , pp. 63
    • De Palma, G.1    Nadal, I.2    Medina, M.3    Donat, E.4    Ribes-Koninckx, C.5    Calabuig, M.6
  • 25
    • 84872847381 scopus 로고    scopus 로고
    • The gut microbial metabolome: Modulation of cancer risk in obese individuals
    • Russell WR, Duncan SH, Flint HJ. The gut microbial metabolome: modulation of cancer risk in obese individuals. Proc Nutr Soc 2013; 72: 178-188.
    • (2013) Proc Nutr Soc , vol.72 , pp. 178-188
    • Russell, W.R.1    Duncan, S.H.2    Flint, H.J.3
  • 26
    • 84901331442 scopus 로고    scopus 로고
    • The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota
    • Balmer ML, Slack E, de Gottardi A, Lawson MA, Hapfelmeier S, Miele L et al. The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota. Sci Tansl Med 2014; 6: 237-266.
    • (2014) Sci Tansl Med , vol.6 , pp. 237-266
    • Balmer, M.L.1    Slack, E.2    De Gottardi, A.3    Lawson, M.A.4    Hapfelmeier, S.5    Miele, L.6
  • 28
    • 84874688283 scopus 로고    scopus 로고
    • Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX(3)CR1(hi) cells
    • Diehl GE, Longman RS, Zhang JX, Breart B, Galan C, Cuesta A et al. Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX(3)CR1(hi) cells. Nature 2013; 494: 116-120.
    • (2013) Nature , vol.494 , pp. 116-120
    • Diehl, G.E.1    Longman, R.S.2    Zhang, J.X.3    Breart, B.4    Galan, C.5    Cuesta, A.6
  • 29
    • 84857444508 scopus 로고    scopus 로고
    • B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage
    • Kirkland D, Benson A, Mirpuri J, Pifer R, Hou B, DeFranco AL et al. B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage. Immunity 2012; 36: 228-238.
    • (2012) Immunity , vol.36 , pp. 228-238
    • Kirkland, D.1    Benson, A.2    Mirpuri, J.3    Pifer, R.4    Hou, B.5    DeFranco, A.L.6
  • 30
    • 79251584066 scopus 로고    scopus 로고
    • Bifidobacteria can protect from enteropathogenic infection through production of acetate
    • Fukuda S, Toh H, Hase K, Oshima K, Nakanishi Y, Yoshimura K et al. Bifidobacteria can protect from enteropathogenic infection through production of acetate. Nature 2011; 469: 543-547.
    • (2011) Nature , vol.469 , pp. 543-547
    • Fukuda, S.1    Toh, H.2    Hase, K.3    Oshima, K.4    Nakanishi, Y.5    Yoshimura, K.6
  • 31
    • 58149091806 scopus 로고    scopus 로고
    • The perfect storm for type 1 diabetes: The complex interplay between intestinal microbiota, gut permeability, and mucosal immunity
    • Vaarala O, Atkinson MA, Neu J. The "perfect storm" for type 1 diabetes: the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity. Diabetes 2008; 57: 2555-2562.
    • (2008) Diabetes , vol.57 , pp. 2555-2562
    • Vaarala, O.1    Atkinson, M.A.2    Neu, J.3
  • 32
    • 84871235774 scopus 로고    scopus 로고
    • Role of urea in intestinal barrier dysfunction and disruption of epithelial tight junction in chronic kidney disease
    • Vaziri ND, Yuan J, Norris K. Role of urea in intestinal barrier dysfunction and disruption of epithelial tight junction in chronic kidney disease. Am J Nephrol 2013; 37: 1-6.
    • (2013) Am J Nephrol , vol.37 , pp. 1-6
    • Vaziri, N.D.1    Yuan, J.2    Norris, K.3
  • 33
    • 14944359128 scopus 로고    scopus 로고
    • Resistant starch attenuates colonic DNA damage induced by higher dietary protein in rats
    • Toden S, Bird AR, Topping DL, Conlon MA. Resistant starch attenuates colonic DNA damage induced by higher dietary protein in rats. Nutr Cancer 2005; 51: 45-51.
    • (2005) Nutr Cancer , vol.51 , pp. 45-51
    • Toden, S.1    Bird, A.R.2    Topping, D.L.3    Conlon, M.A.4
  • 34
    • 56049127918 scopus 로고    scopus 로고
    • Effects of high-amylose maize starch and butyrylated high-amylose maize starch on azoxymethane-induced intestinal cancer in rats
    • Clarke JM, Topping DL, Bird AR, Young GP, Cobiac L. Effects of high-amylose maize starch and butyrylated high-amylose maize starch on azoxymethane-induced intestinal cancer in rats. Carcinogenesis 2008; 29: 2190-2194.
    • (2008) Carcinogenesis , vol.29 , pp. 2190-2194
    • Clarke, J.M.1    Topping, D.L.2    Bird, A.R.3    Young, G.P.4    Cobiac, L.5
  • 35
    • 84862104613 scopus 로고    scopus 로고
    • Resistant starches protect against colonic DNA damage and alter microbiota and gene expression in rats fed a Western diet
    • Conlon MA, Kerr CA, McSweeney CS, Dunne RA, Shaw JM, Kang S et al. Resistant starches protect against colonic DNA damage and alter microbiota and gene expression in rats fed a Western diet. J Nutr 2012; 142: 832-840.
    • (2012) J Nutr , vol.142 , pp. 832-840
    • Conlon, M.A.1    Kerr, C.A.2    McSweeney, C.S.3    Dunne, R.A.4    Shaw, J.M.5    Kang, S.6
  • 37
    • 70350666634 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
    • Maslowski KM, Vieira AT, Ng A, Kranich J, Sierro F, Yu D et al. Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature 2009; 461: 1282-1286.
    • (2009) Nature , vol.461 , pp. 1282-1286
    • Maslowski, K.M.1    Vieira, A.T.2    Ng, A.3    Kranich, J.4    Sierro, F.5    Yu, D.6
  • 38
    • 0038363378 scopus 로고    scopus 로고
    • The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
    • Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D et al. The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem 2003; 278: 11312-11319.
    • (2003) J Biol Chem , vol.278 , pp. 11312-11319
    • Brown, A.J.1    Goldsworthy, S.M.2    Barnes, A.A.3    Eilert, M.M.4    Tcheang, L.5    Daniels, D.6
  • 39
    • 84894261181 scopus 로고    scopus 로고
    • The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival
    • Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Lan L et al. The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival. Cancer Res 2014; 74: 1166-1178.
    • (2014) Cancer Res , vol.74 , pp. 1166-1178
    • Elangovan, S.1    Pathania, R.2    Ramachandran, S.3    Ananth, S.4    Padia, R.N.5    Lan, L.6
  • 41
    • 84892449521 scopus 로고    scopus 로고
    • Activation of gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis
    • Singh N, Gurav A, Sivaprakasam S, Brady E, Padia R, Shi H et al. Activation of gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis. Immunity 2014; 40: 128-139.
    • (2014) Immunity , vol.40 , pp. 128-139
    • Singh, N.1    Gurav, A.2    Sivaprakasam, S.3    Brady, E.4    Padia, R.5    Shi, H.6
  • 42
    • 84926367699 scopus 로고    scopus 로고
    • Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome
    • Macia L, Tan J, Vieira AT, Leach K, Stanley D, Luong S et al. Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome. Nat Commun 2015; 6: 6734.
    • (2015) Nat Commun , vol.6 , pp. 6734
    • Macia, L.1    Tan, J.2    Vieira, A.T.3    Leach, K.4    Stanley, D.5    Luong, S.6
  • 43
    • 70350509805 scopus 로고    scopus 로고
    • Intestinal mucosal barrier function in health and disease
    • Turner JR. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol 2009; 9: 799-809.
    • (2009) Nat Rev Immunol , vol.9 , pp. 799-809
    • Turner, J.R.1
  • 44
    • 84939560264 scopus 로고    scopus 로고
    • Development of Gut-Associated lymphoid tissues
    • Mestecky V et al (eds) Academic press
    • Flach M, Diefenbach A. Development of Gut-Associated Lymphoid Tissues. In: Mestecky V et al (eds). Mucosal Immunology. 4th edn, vol. 1-2, Academic press, 2015, pp 31-42.
    • (2015) Mucosal Immunology. 4th Edn , vol.1-2 , pp. 31-42
    • Flach, M.1    Diefenbach, A.2
  • 45
    • 79959961092 scopus 로고    scopus 로고
    • Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis
    • Lepage P, Hasler R, Spehlmann ME, Rehman A, Zvirbliene A, Begun A et al. Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis. Gastroenterology 2011; 141: 227-236.
    • (2011) Gastroenterology , vol.141 , pp. 227-236
    • Lepage, P.1    Hasler, R.2    Spehlmann, M.E.3    Rehman, A.4    Zvirbliene, A.5    Begun, A.6
  • 46
    • 79951917669 scopus 로고    scopus 로고
    • Mouse and human intestinal immunity: Same ballpark, different players; Different rules, same score
    • Gibbons DL, Spencer J. Mouse and human intestinal immunity: same ballpark, different players; Different rules, same score. Mucosal Immunol 2011; 4: 148-157.
    • (2011) Mucosal Immunol , vol.4 , pp. 148-157
    • Gibbons, D.L.1    Spencer, J.2
  • 47
    • 84879402478 scopus 로고    scopus 로고
    • The role of the immune system in governing host-microbe interactions in the intestine
    • Brown EM, Sadarangani M, Finlay BB. The role of the immune system in governing host-microbe interactions in the intestine. Nat Immunol 2013; 14: 660-667.
    • (2013) Nat Immunol , vol.14 , pp. 660-667
    • Brown, E.M.1    Sadarangani, M.2    Finlay, B.B.3
  • 48
    • 84867807929 scopus 로고    scopus 로고
    • Innate lymphoid cell interactions with microbiota: Implications for intestinal health and disease
    • Sonnenberg G, Artis D. Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease. Immunity 2012; 37: 601-610.
    • (2012) Immunity , vol.37 , pp. 601-610
    • Sonnenberg, G.1    Artis, D.2
  • 49
    • 84868615556 scopus 로고    scopus 로고
    • IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
    • Huber S, Gagliani N, Zenewicz LA, Huber FJ, Bosurgi L, Hu B et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature 2012; 491: 259-263.
    • (2012) Nature , vol.491 , pp. 259-263
    • Huber, S.1    Gagliani, N.2    Zenewicz, L.A.3    Huber, F.J.4    Bosurgi, L.5    Hu, B.6
  • 50
    • 42649095378 scopus 로고    scopus 로고
    • Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor
    • Quintana FJ, Basso AS, Iglesias AH, Korn T, Farez MF, Bettelli E et al. Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor. Nature 2008; 453: 65-71.
    • (2008) Nature , vol.453 , pp. 65-71
    • Quintana, F.J.1    Basso, A.S.2    Iglesias, A.H.3    Korn, T.4    Farez, M.F.5    Bettelli, E.6
  • 51
    • 84861989207 scopus 로고    scopus 로고
    • Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria
    • Sonnenberg GF, Monticelli LA, Alenghat T, Fung TC, Hutnick NA, Kunisawa J et al. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science 2012; 336: 1321-1325.
    • (2012) Science , vol.336 , pp. 1321-1325
    • Sonnenberg, G.F.1    Monticelli, L.A.2    Alenghat, T.3    Fung, T.C.4    Hutnick, N.A.5    Kunisawa, J.6
  • 52
    • 84881051317 scopus 로고    scopus 로고
    • Immunology. Feed your Tregs more fiber
    • Bollrath J, Powrie F. Immunology. Feed your Tregs more fiber. Science 2013; 341: 463-464.
    • (2013) Science , vol.341 , pp. 463-464
    • Bollrath, J.1    Powrie, F.2
  • 53
    • 84890564250 scopus 로고    scopus 로고
    • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
    • Furusawa Y, Obata Y, Fukuda S, Endo TA, Nakato G, Takahashi D et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature 2013; 504: 446-450.
    • (2013) Nature , vol.504 , pp. 446-450
    • Furusawa, Y.1    Obata, Y.2    Fukuda, S.3    Endo, T.A.4    Nakato, G.5    Takahashi, D.6
  • 54
    • 84881068658 scopus 로고    scopus 로고
    • The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis
    • Smith PM, Howitt MR, Panikov N, Michaud M, Gallini CA, Bohlooly YM et al. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science 2013; 341: 569-573.
    • (2013) Science , vol.341 , pp. 569-573
    • Smith, P.M.1    Howitt, M.R.2    Panikov, N.3    Michaud, M.4    Gallini, C.A.5    Bohlooly, Y.M.6
  • 55
    • 79956315886 scopus 로고    scopus 로고
    • Intestinal bacterial colonization induces mutualistic regulatory T cell responses
    • Geuking MB, Cahenzli J, Lawson MA, Ng DC, Slack E, Hapfelmeier S et al. Intestinal bacterial colonization induces mutualistic regulatory T cell responses. Immunity 2011; 34: 794-806.
    • (2011) Immunity , vol.34 , pp. 794-806
    • Geuking, M.B.1    Cahenzli, J.2    Lawson, M.A.3    Ng, D.C.4    Slack, E.5    Hapfelmeier, S.6
  • 56
    • 84934987107 scopus 로고    scopus 로고
    • Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites
    • Thorburn AN, McKenzie CI, Shen S, Stanley D, Macia L, Mason LJ et al. Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nat Commun 2015; 6: 7320.
    • (2015) Nat Commun , vol.6 , pp. 7320
    • Thorburn, A.N.1    McKenzie, C.I.2    Shen, S.3    Stanley, D.4    Macia, L.5    Mason, L.J.6
  • 57
    • 69949111703 scopus 로고    scopus 로고
    • The core gut microbiome, energy balance and obesity
    • Turnbaugh PJ, Gordon JI. The core gut microbiome, energy balance and obesity. J Physiol 2009; 587: 4153-4158.
    • (2009) J Physiol , vol.587 , pp. 4153-4158
    • Turnbaugh, P.J.1    Gordon, J.I.2
  • 58
    • 84879888338 scopus 로고    scopus 로고
    • Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
    • Yoshimoto S, Loo TM, Atarashi K, Kanda H, Sato S, Oyadomari S et al. Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome. Nature 2013; 499: 97-101.
    • (2013) Nature , vol.499 , pp. 97-101
    • Yoshimoto, S.1    Loo, T.M.2    Atarashi, K.3    Kanda, H.4    Sato, S.5    Oyadomari, S.6
  • 60
    • 33847040759 scopus 로고    scopus 로고
    • Increased intestinal permeability in obese mice: New evidence in the pathogenesis of nonalcoholic steatohepatitis
    • Brun P, Castagliuolo I, Di Leo V, Buda A, Pinzani M, Palù G et al. Increased intestinal permeability in obese mice: New evidence in the pathogenesis of nonalcoholic steatohepatitis. Am J Physiol 2007; 292: G518-G525.
    • (2007) Am J Physiol , vol.292 , pp. G518-G525
    • Brun, P.1    Castagliuolo, I.2    Di Leo, V.3    Buda, A.4    Pinzani, M.5    Palù, G.6
  • 61
    • 84858779974 scopus 로고    scopus 로고
    • Increased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice
    • Lam YY, Ha CWY, Campbell CR, Mitchell AJ, Dinudom A, Oscarsson J et al. Increased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice. PLoS ONE 2012; 7: e34233.
    • (2012) PLoS ONE , vol.7 , pp. e34233
    • Lam, Y.Y.1    Ha, C.W.Y.2    Campbell, C.R.3    Mitchell, A.J.4    Dinudom, A.5    Oscarsson, J.6
  • 62
  • 63
    • 47949095562 scopus 로고    scopus 로고
    • Susceptibility to gut leakiness: A possible mechanism for endotoxaemia in nonalcoholic steatohepatitis
    • Farhadi A, Gundlapalli S, Shaikh M, Frantzides C, Harrell L, Kwasny MM et al. Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in nonalcoholic steatohepatitis. Liver Int 2008; 28: 1026-1033.
    • (2008) Liver Int , vol.28 , pp. 1026-1033
    • Farhadi, A.1    Gundlapalli, S.2    Shaikh, M.3    Frantzides, C.4    Harrell, L.5    Kwasny, M.M.6
  • 64
    • 84862067310 scopus 로고    scopus 로고
    • Circulating zonulin, a marker of intestinal permeability, is increased in association with obesityassociated insulin resistance
    • Moreno-Navarrete JM, Sabater M, Ortega F, Ricart W, Fernández-Real JM. Circulating zonulin, a marker of intestinal permeability, is increased in association with obesityassociated insulin resistance. PLoS ONE 2012; 7: e37160.
    • (2012) PLoS ONE , vol.7 , pp. e37160
    • Moreno-Navarrete, J.M.1    Sabater, M.2    Ortega, F.3    Ricart, W.4    Fernández-Real, J.M.5
  • 65
    • 84925581887 scopus 로고    scopus 로고
    • Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress
    • Hasnain SZ, Borg DJ, Harcourt BE, Tong H, Sheng YH, Ng CP et al. Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress. Nat Med 2014; 20: 1417-1426.
    • (2014) Nat Med , vol.20 , pp. 1417-1426
    • Hasnain, S.Z.1    Borg, D.J.2    Harcourt, B.E.3    Tong, H.4    Sheng, Y.H.5    Ng, C.P.6
  • 66
    • 84908311821 scopus 로고    scopus 로고
    • Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes
    • Wang X, Ota N, Manzanillo P, Kates L, Zavala-Solorio J, Eidenschenk C et al. Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes. Nature 2014; 514: 237-241.
    • (2014) Nature , vol.514 , pp. 237-241
    • Wang, X.1    Ota, N.2    Manzanillo, P.3    Kates, L.4    Zavala-Solorio, J.5    Eidenschenk, C.6
  • 67
    • 84907208430 scopus 로고    scopus 로고
    • Innate lymphoid cells regulate intestinal epithelial cell glycosylation
    • Goto Y, Obata T, Kunisawa J, Sato S, Ivanov II, Lamichhane A et al. Innate lymphoid cells regulate intestinal epithelial cell glycosylation. Science 2014; 345: 1254009.
    • (2014) Science , vol.345 , pp. 1254009
    • Goto, Y.1    Obata, T.2    Kunisawa, J.3    Sato, S.4    Ivanov, I.I.5    Lamichhane, A.6
  • 68
    • 56749146467 scopus 로고    scopus 로고
    • Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
    • Bouskra D, Brezillon C, Berard M, Werts C, Varona R, Boneca IG et al. Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature 2008; 456: 507-510.
    • (2008) Nature , vol.456 , pp. 507-510
    • Bouskra, D.1    Brezillon, C.2    Berard, M.3    Werts, C.4    Varona, R.5    Boneca, I.G.6
  • 70
    • 65249099918 scopus 로고    scopus 로고
    • Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability
    • Cani PD, Possemiers S, Van de Wiele T, Guiot Y, Everard A, Rottier O et al. Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Gut 2009; 58: 1091-1103.
    • (2009) Gut , vol.58 , pp. 1091-1103
    • Cani, P.D.1    Possemiers, S.2    Van De Wiele, T.3    Guiot, Y.4    Everard, A.5    Rottier, O.6
  • 71
    • 84949772416 scopus 로고    scopus 로고
    • Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
    • Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chatelier E, Sunagawa S et al. Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature 2015; 528: 262-266.
    • (2015) Nature , vol.528 , pp. 262-266
    • Forslund, K.1    Hildebrand, F.2    Nielsen, T.3    Falony, G.4    Le Chatelier, E.5    Sunagawa, S.6
  • 72
    • 84856509724 scopus 로고    scopus 로고
    • Shortchain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2
    • Tolhurst G, Heffron H, Lam YS, Parker HE, Habib AM, Diakogiannaki E et al. Shortchain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2. Diabetes 2012; 61: 364-371.
    • (2012) Diabetes , vol.61 , pp. 364-371
    • Tolhurst, G.1    Heffron, H.2    Lam, Y.S.3    Parker, H.E.4    Habib, A.M.5    Diakogiannaki, E.6
  • 73
    • 84904000735 scopus 로고    scopus 로고
    • Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis
    • Perry RJ, Zhang XM, Zhang D, Kumashiro N, Camporez JP, Cline GW et al. Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis. Nat Med 2014; 20: 759-763.
    • (2014) Nat Med , vol.20 , pp. 759-763
    • Perry, R.J.1    Zhang, X.M.2    Zhang, D.3    Kumashiro, N.4    Camporez, J.P.5    Cline, G.W.6
  • 74
    • 0742305675 scopus 로고    scopus 로고
    • Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41
    • Xiong Y, Miyamoto N, Shibata K, Valasek MA, Motoike T, Kedzierski RM et al. Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci USA 2004; 101: 1045-1050.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1045-1050
    • Xiong, Y.1    Miyamoto, N.2    Shibata, K.3    Valasek, M.A.4    Motoike, T.5    Kedzierski, R.M.6
  • 75
    • 77952957384 scopus 로고    scopus 로고
    • Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids
    • Zaibi MS, Stocker CJ, O'Dowd J, Davies A, Bellahcene M, Cawthorne MA et al. Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids. FEBS Lett 2010; 584: 2381-2386.
    • (2010) FEBS Lett , vol.584 , pp. 2381-2386
    • Zaibi, M.S.1    Stocker, C.J.2    O'Dowd, J.3    Davies, A.4    Bellahcene, M.5    Cawthorne, M.A.6
  • 76
    • 84858285480 scopus 로고    scopus 로고
    • Propionic acid affects immune status and metabolism in adipose tissue from overweight subjects
    • Al-Lahham S, Roelofsen H, Rezaee F, Weening D, Hoek A, Vonk R et al. Propionic acid affects immune status and metabolism in adipose tissue from overweight subjects. Eur J Clin Invest 2012; 42: 357-364.
    • (2012) Eur J Clin Invest , vol.42 , pp. 357-364
    • Al-Lahham, S.1    Roelofsen, H.2    Rezaee, F.3    Weening, D.4    Hoek, A.5    Vonk, R.6
  • 77
  • 79
    • 84922620529 scopus 로고    scopus 로고
    • Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes
    • Tang C, Ahmed K, Gille A, Lu S, Grone HJ, Tunaru S et al. Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes. Nat Med 2015; 21: 173-177.
    • (2015) Nat Med , vol.21 , pp. 173-177
    • Tang, C.1    Ahmed, K.2    Gille, A.3    Lu, S.4    Grone, H.J.5    Tunaru, S.6
  • 80
    • 0027242010 scopus 로고
    • Plasma acetate levels in a group of obese diabetic, obese normoglycemic, and control subjects and their relationships with other blood parameters
    • Todesco T, Zamboni M, Armellini F, Bissoli L, Turcato E, Piemonte G et al. Plasma acetate levels in a group of obese diabetic, obese normoglycemic, and control subjects and their relationships with other blood parameters. Am J Gastroenterol 1993; 88: 751-755.
    • (1993) Am J Gastroenterol , vol.88 , pp. 751-755
    • Todesco, T.1    Zamboni, M.2    Armellini, F.3    Bissoli, L.4    Turcato, E.5    Piemonte, G.6
  • 81
    • 84877964137 scopus 로고    scopus 로고
    • Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content
    • Bellahcene M, O'Dowd JF, Wargent ET, Zaibi MS, Hislop DC, Ngala RA et al. Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content. Br J Nutr 2013; 109: 1755-1764.
    • (2013) Br J Nutr , vol.109 , pp. 1755-1764
    • Bellahcene, M.1    O'Dowd, J.F.2    Wargent, E.T.3    Zaibi, M.S.4    Hislop, D.C.5    Ngala, R.A.6
  • 82
    • 78650800467 scopus 로고    scopus 로고
    • Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet
    • Bjursell M, Admyre T, Goransson M, Marley AE, Smith DM, Oscarsson J et al. Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet. Am J Physiol Endocrinol Metab 2011; 300: E211-E220.
    • (2011) Am J Physiol Endocrinol Metab , vol.300 , pp. E211-E220
    • Bjursell, M.1    Admyre, T.2    Goransson, M.3    Marley, A.E.4    Smith, D.M.5    Oscarsson, J.6
  • 83
    • 84878579044 scopus 로고    scopus 로고
    • The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43
    • Kimura I, Ozawa K, Inoue D, Imamura T, Kimura K, Maeda T et al. The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43. Nat Commun 2013; 4: 1829.
    • (2013) Nat Commun , vol.4 , pp. 1829
    • Kimura, I.1    Ozawa, K.2    Inoue, D.3    Imamura, T.4    Kimura, K.5    Maeda, T.6
  • 84
    • 84859587827 scopus 로고    scopus 로고
    • Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms
    • Lin HV, Frassetto A, Kowalik EJ Jr., Nawrocki AR, Lu MM, Kosinski JR et al. Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. PLoS ONE 2012; 7: e35240.
    • (2012) PLoS ONE , vol.7 , pp. e35240
    • Lin, H.V.1    Frassetto, A.2    Kowalik, E.J.3    Nawrocki, A.R.4    Lu, M.M.5    Kosinski, J.R.6
  • 85
    • 55949091259 scopus 로고    scopus 로고
    • Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41
    • Samuel BS, Shaito A, Motoike T, Rey FE, Backhed F, Manchester JK et al. Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41. Proc Natl Acad Sci USA 2008; 105: 16767-16772.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16767-16772
    • Samuel, B.S.1    Shaito, A.2    Motoike, T.3    Rey, F.E.4    Backhed, F.5    Manchester, J.K.6
  • 86
    • 68349148211 scopus 로고    scopus 로고
    • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
    • Feuerer M, Herrero L, Cipolletta D, Naaz A, Wong J, Nayer A et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009; 15: 930-939.
    • (2009) Nat Med , vol.15 , pp. 930-939
    • Feuerer, M.1    Herrero, L.2    Cipolletta, D.3    Naaz, A.4    Wong, J.5    Nayer, A.6
  • 87
    • 84924284481 scopus 로고    scopus 로고
    • Post-translational modifications regulate class IIa histone deacetylase (HDAC) function in health and disease
    • Mathias RA, Guise AJ, Cristea IM. Post-translational modifications regulate class IIa histone deacetylase (HDAC) function in health and disease. Mol Cell Proteomics 2015; 14: 456-470.
    • (2015) Mol Cell Proteomics , vol.14 , pp. 456-470
    • Mathias, R.A.1    Guise, A.J.2    Cristea, I.M.3
  • 89
    • 84891751641 scopus 로고    scopus 로고
    • HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease during high-fat feeding
    • Chatterjee TK, Basford JE, Knoll E, Tong WS, Blanco V, Blomkalns AL et al. HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease during high-fat feeding. Diabetes 2014; 63: 176-187.
    • (2014) Diabetes , vol.63 , pp. 176-187
    • Chatterjee, T.K.1    Basford, J.E.2    Knoll, E.3    Tong, W.S.4    Blanco, V.5    Blomkalns, A.L.6
  • 90
    • 84901444529 scopus 로고    scopus 로고
    • The gut microbiome, kidney disease, and targeted interventions
    • Ramezani A, Raj DS. The gut microbiome, kidney disease, and targeted interventions. J Am Soc Nephrol 2014; 25: 657-670.
    • (2014) J Am Soc Nephrol , vol.25 , pp. 657-670
    • Ramezani, A.1    Raj, D.S.2
  • 91
    • 84984616719 scopus 로고    scopus 로고
    • Resistant starch alters gut microbiome and metabolomics profiles concurrent with amelioration of chronic kidney disease in rats
    • Kieffer DA, Piccolo BD, Vaziri ND, Liu S, Lau WL, Khazaeli M et al. Resistant starch alters gut microbiome and metabolomics profiles concurrent with amelioration of chronic kidney disease in rats. Am J Physiol Renal Physiol 2016; 310: F857-F871.
    • (2016) Am J Physiol Renal Physiol , vol.310 , pp. F857-F871
    • Kieffer, D.A.1    Piccolo, B.D.2    Vaziri, N.D.3    Liu, S.4    Lau, W.L.5    Khazaeli, M.6
  • 93
    • 84883520311 scopus 로고    scopus 로고
    • Epigenetics of progression of chronic kidney disease: Fact or fantasy?
    • Wing MR, Ramezani A, Gill HS, Devaney JM, Raj DS. Epigenetics of progression of chronic kidney disease: fact or fantasy? Semin Nephrol 2013; 33: 363-374.
    • (2013) Semin Nephrol , vol.33 , pp. 363-374
    • Wing, M.R.1    Ramezani, A.2    Gill, H.S.3    Devaney, J.M.4    Raj, D.S.5
  • 94
    • 84908265816 scopus 로고    scopus 로고
    • Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
    • Falkenberg KJ, Johnstone RW. Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders. Nat Rev Drug Discov 2014; 13: 673-691.
    • (2014) Nat Rev Drug Discov , vol.13 , pp. 673-691
    • Falkenberg, K.J.1    Johnstone, R.W.2
  • 95
    • 84855448173 scopus 로고    scopus 로고
    • HDAC inhibitors: Modulating leukocyte differentiation, survival, proliferation and inflammation
    • Sweet MJ, Shakespear MR, Kamal NA, Fairlie DP. HDAC inhibitors: modulating leukocyte differentiation, survival, proliferation and inflammation. Immunol Cell Biol 2012; 90: 14-22.
    • (2012) Immunol Cell Biol , vol.90 , pp. 14-22
    • Sweet, M.J.1    Shakespear, M.R.2    Kamal, N.A.3    Fairlie, D.P.4
  • 96
    • 77649115437 scopus 로고    scopus 로고
    • Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression
    • Yamaguchi T, Cubizolles F, Zhang Y, Reichert N, Kohler H, Seiser C et al. Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression. Genes Dev 2010; 24: 455-469.
    • (2010) Genes Dev , vol.24 , pp. 455-469
    • Yamaguchi, T.1    Cubizolles, F.2    Zhang, Y.3    Reichert, N.4    Kohler, H.5    Seiser, C.6
  • 97
    • 33751184610 scopus 로고    scopus 로고
    • Histone acetylation is associated with differential gene expression in the rapid and robust memory CD8+ T-cell response
    • Fann M, Godlove JM, Catalfamo M, Wood III WH, Chrest FJ, Chun N et al. Histone acetylation is associated with differential gene expression in the rapid and robust memory CD8+ T-cell response. Blood 2006; 108: 3363-3370.
    • (2006) Blood , vol.108 , pp. 3363-3370
    • Fann, M.1    Godlove, J.M.2    Catalfamo, M.3    Wood, W.H.4    Chrest, F.J.5    Chun, N.6
  • 98
    • 49049110982 scopus 로고    scopus 로고
    • Cutting edge: Chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells
    • Northrop JK, Wells AD, Shen H. Cutting edge: chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells. J Immunol 2008; 181: 865-868.
    • (2008) J Immunol , vol.181 , pp. 865-868
    • Northrop, J.K.1    Wells, A.D.2    Shen, H.3
  • 99
    • 74449093175 scopus 로고    scopus 로고
    • Histone deacetylases and the immunological network: Implications in cancer and inflammation
    • Villagra A, Sotomayor EM, Seto E. Histone deacetylases and the immunological network: implications in cancer and inflammation. Oncogene 2010; 29: 157-173.
    • (2010) Oncogene , vol.29 , pp. 157-173
    • Villagra, A.1    Sotomayor, E.M.2    Seto, E.3
  • 100
    • 77949272755 scopus 로고    scopus 로고
    • Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice
    • Lee AS, Gibson DL, Zhang Y, Sham HP, Vallance BA, Dutz JP. Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice. Diabetologia 2010; 53: 741-748.
    • (2010) Diabetologia , vol.53 , pp. 741-748
    • Lee, A.S.1    Gibson, D.L.2    Zhang, Y.3    Sham, H.P.4    Vallance, B.A.5    Dutz, J.P.6
  • 102
    • 33745311630 scopus 로고    scopus 로고
    • Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives
    • Sapone A, de Magistris L, Pietzak M, Clemente MG, Tripathi A, Cucca F et al. Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives. Diabetes 2006; 55: 1443-1449.
    • (2006) Diabetes , vol.55 , pp. 1443-1449
    • Sapone, A.1    De Magistris, L.2    Pietzak, M.3    Clemente, M.G.4    Tripathi, A.5    Cucca, F.6
  • 103
    • 78649326409 scopus 로고    scopus 로고
    • Restoration of impaired intestinal barrier function by the hydrolysed casein diet contributes to the prevention of type 1 diabetes in the diabetes-prone BioBreeding rat
    • Visser JTJ, Lammers K, Hoogendijk A, Boer MW, Brugman S, Beijer-Liefers S et al. Restoration of impaired intestinal barrier function by the hydrolysed casein diet contributes to the prevention of type 1 diabetes in the diabetes-prone BioBreeding rat. Diabetologia 2010; 53: 2621-2628.
    • (2010) Diabetologia , vol.53 , pp. 2621-2628
    • Visser, J.T.J.1    Lammers, K.2    Hoogendijk, A.3    Boer, M.W.4    Brugman, S.5    Beijer-Liefers, S.6
  • 104
    • 84872592295 scopus 로고    scopus 로고
    • Fecal microbiota composition differs between children with beta-cell autoimmunity and those without
    • de Goffau MC, Luopajarvi K, Knip M, Ilonen J, Ruohtula T, Harkonen T et al. Fecal microbiota composition differs between children with beta-cell autoimmunity and those without. Diabetes 2013; 62: 1238-1244.
    • (2013) Diabetes , vol.62 , pp. 1238-1244
    • De Goffau, M.C.1    Luopajarvi, K.2    Knip, M.3    Ilonen, J.4    Ruohtula, T.5    Harkonen, T.6
  • 106
  • 108
    • 23844493809 scopus 로고    scopus 로고
    • Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse
    • Calcinaro F, Dionisi S, Marinaro M, Candeloro P, Bonato V, Marzotti S et al. Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse. Diabetologia 2005; 48: 1565-1575.
    • (2005) Diabetologia , vol.48 , pp. 1565-1575
    • Calcinaro, F.1    Dionisi, S.2    Marinaro, M.3    Candeloro, P.4    Bonato, V.5    Marzotti, S.6
  • 109
    • 33845688616 scopus 로고    scopus 로고
    • Probiotics for the prevention of beta cell autoimmunity in children at genetic risk of type 1 diabetes- The PRODIA study
    • Ljungberg M, Korpela R, Ilonen J, Ludvigsson J, Vaarala O. Probiotics for the prevention of beta cell autoimmunity in children at genetic risk of type 1 diabetes-the PRODIA study. Ann N Y Acad Sci 2006; 1079: 360-364.
    • (2006) Ann N y Acad Sci , vol.1079 , pp. 360-364
    • Ljungberg, M.1    Korpela, R.2    Ilonen, J.3    Ludvigsson, J.4    Vaarala, O.5
  • 110
    • 84890550163 scopus 로고    scopus 로고
    • Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
    • Arpaia N, Campbell C, Fan X, Dikiy S, Van Der Veeken J, Deroos P et al. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation. Nature 2013; 504: 451-455.
    • (2013) Nature , vol.504 , pp. 451-455
    • Arpaia, N.1    Campbell, C.2    Fan, X.3    Dikiy, S.4    Van Der Veeken, J.5    Deroos, P.6
  • 111
    • 16844363097 scopus 로고    scopus 로고
    • A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
    • Fontenot JD, Rudensky AY. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat Immunol 2005; 6: 331-337.
    • (2005) Nat Immunol , vol.6 , pp. 331-337
    • Fontenot, J.D.1    Rudensky, A.Y.2
  • 112
    • 84888266953 scopus 로고    scopus 로고
    • Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells
    • Zhang Y, Maksimovic J, Naselli G, Qian J, Chopin M, Blewitt ME et al. Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells. Blood 2013; 122: 2823-2836.
    • (2013) Blood , vol.122 , pp. 2823-2836
    • Zhang, Y.1    Maksimovic, J.2    Naselli, G.3    Qian, J.4    Chopin, M.5    Blewitt, M.E.6
  • 113
    • 34248379172 scopus 로고    scopus 로고
    • FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression
    • Li B, Samanta A, Song X, Iacono KT, Bembas K, Tao R et al. FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression. Proc Natl Acad Sci USA 2007; 104: 4571-4576.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 4571-4576
    • Li, B.1    Samanta, A.2    Song, X.3    Iacono, K.T.4    Bembas, K.5    Tao, R.6
  • 114
    • 35948980739 scopus 로고    scopus 로고
    • Deacetylase inhibition promotes the generation and function of regulatory T cells
    • Tao R, de Zoeten EF, Ozkaynak E, Chen C, Wang L, Porrett PM et al. Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med 2007; 13: 1299-1307.
    • (2007) Nat Med , vol.13 , pp. 1299-1307
    • Tao, R.1    De Zoeten, E.F.2    Ozkaynak, E.3    Chen, C.4    Wang, L.5    Porrett, P.M.6
  • 116
    • 40749144079 scopus 로고    scopus 로고
    • Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells
    • Marinõ E, Batten M, Groom J, Walters S, Liuwantara D, Mackay F et al. Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells. Diabetes 2008; 57: 395-404.
    • (2008) Diabetes , vol.57 , pp. 395-404
    • Marinõ, E.1    Batten, M.2    Groom, J.3    Walters, S.4    Liuwantara, D.5    MacKay, F.6
  • 117
    • 84868008849 scopus 로고    scopus 로고
    • B-cell cross-presentation of autologous antigen precipitates diabetes
    • Marino E, Tan B, Binge L, Mackay CR, Grey ST. B-cell cross-presentation of autologous antigen precipitates diabetes. Diabetes 2012; 61: 2893-2905.
    • (2012) Diabetes , vol.61 , pp. 2893-2905
    • Marino, E.1    Tan, B.2    Binge, L.3    MacKay, C.R.4    Grey, S.T.5
  • 119
    • 84916910420 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses
    • White CA, Pone EJ, Lam T, Tat C, Hayama KL, Li G et al. Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses. J Immunol 2014; 193: 5933-5950.
    • (2014) J Immunol , vol.193 , pp. 5933-5950
    • White, C.A.1    Pone, E.J.2    Lam, T.3    Tat, C.4    Hayama, K.L.5    Li, G.6
  • 121
    • 79960062797 scopus 로고    scopus 로고
    • IL-15 interferes with suppressive activity of intestinal regulatory T cells expanded in Celiac disease
    • Zanzi D, Stefanile R, Santagata S, Iaffaldano L, Iaquinto G, Giardullo N et al. IL-15 interferes with suppressive activity of intestinal regulatory T cells expanded in Celiac disease. Am J Gastroenterol 2011; 106: 1308-1317.
    • (2011) Am J Gastroenterol , vol.106 , pp. 1308-1317
    • Zanzi, D.1    Stefanile, R.2    Santagata, S.3    Iaffaldano, L.4    Iaquinto, G.5    Giardullo, N.6
  • 122
    • 53549131723 scopus 로고    scopus 로고
    • Systematic review: The evidence base for long-term management of coeliac disease
    • Haines ML, Anderson RP, Gibson PR. Systematic review: the evidence base for long-term management of coeliac disease. Alimentary Pharmacol Ther 2008; 28: 1042-1066.
    • (2008) Alimentary Pharmacol Ther , vol.28 , pp. 1042-1066
    • Haines, M.L.1    Anderson, R.P.2    Gibson, P.R.3
  • 124
    • 33847791142 scopus 로고    scopus 로고
    • Perinatal maternal application of Lactobacillus rhamnosus GG suppresses allergic airway inflammation in mouse offspring
    • Blümer N, Sel S, Virna S, Patrascan CC, Zimmermann S, Herz U et al. Perinatal maternal application of Lactobacillus rhamnosus GG suppresses allergic airway inflammation in mouse offspring. Clin Exp Allergy 2007; 37: 348-357.
    • (2007) Clin Exp Allergy , vol.37 , pp. 348-357
    • Blümer, N.1    Sel, S.2    Virna, S.3    Patrascan, C.C.4    Zimmermann, S.5    Herz, U.6
  • 125
    • 84927698882 scopus 로고    scopus 로고
    • Development of fecal microbiota transplantation suitable for mainstream medicine
    • Khoruts A, Sadowsky MJ, Hamilton MJ. Development of fecal microbiota transplantation suitable for mainstream medicine. Clin Gastroenterol Hepatol 2015; 13: 246-250.
    • (2015) Clin Gastroenterol Hepatol , vol.13 , pp. 246-250
    • Khoruts, A.1    Sadowsky, M.J.2    Hamilton, M.J.3
  • 126
    • 84871839253 scopus 로고    scopus 로고
    • Early-life environmental determinants of allergic diseases and the wider pandemic of inflammatory noncommunicable diseases
    • Prescott SL. Early-life environmental determinants of allergic diseases and the wider pandemic of inflammatory noncommunicable diseases. J Allergy Clin Immunol 2013; 131: 23-30.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 23-30
    • Prescott, S.L.1


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