Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

Nature Communications

Volumn 6, Issue , 2015, Pages

  Macia, Laurence ^a   Tan, Jian ^a   Vieira, Angelica T ^a,b   Leach, Katie ^a   Stanley, Dragana ^c,d   Luong, Suzanne ^a   Maruya, Mikako ^e   Ian McKenzie, Craig ^a   Hijikata, Atsushi ^e   Wong, Connie ^a   Binge, Lauren ^a   Thorburn, Alison N ^a   Chevalier, Nina ^a   Ang, Caroline ^a   Marino, Eliana ^a   Robert, Remy ^a   Offermanns, Stefan ^f   Teixeira, Mauro M ^b   Moore, Robert J ^a,c   Flavell, Richard A ^g,h   Fagarasan, Sidonia ^e   Mackay, Charles R ^a   more..

^a MONASH UNIVERSITY   (Australia)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^c CSIRO   (Australia)

^d CENTRAL QUEENSLAND UNIVERSITY   (Australia)

^e RIKEN Center for Integrative Medical Sciences   (Japan)

^f MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^g YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; GPR109A RECEPTOR; GPR43 RECEPTOR; INFLAMMASOME; RECEPTOR; SHORT CHAIN FATTY ACID; UNCLASSIFIED DRUG; ACETIC ACID DERIVATIVE; BUTYRIC ACID DERIVATIVE; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; FFAR2 PROTEIN, MOUSE; G PROTEIN COUPLED RECEPTOR; HCAR2 PROTEIN, MOUSE; NICOTINIC RECEPTOR; VOLATILE FATTY ACID;

DIET; DISEASE INCIDENCE; FATTY ACID; FOOD QUALITY; GERM CELL; HOMEOSTASIS; METABOLITE; SIGNALING;

ANIMAL EXPERIMENT; ARTICLE; COLITIS; COLON MUCOSA; CONTROLLED STUDY; DIETARY FIBER; DISEASE EXACERBATION; HOMEOSTASIS AND REGULATION; HYPERPOLARIZATION; INTESTINE EPITHELIUM; INTESTINE FLORA; INTESTINE INJURY; MOUSE; NONHUMAN; POTASSIUM TRANSPORT; RECEPTOR BINDING; ANIMAL; COLON; DRUG EFFECTS; FERMENTATION; GENETICS; HOMEOSTASIS; KNOCKOUT MOUSE; METABOLISM; PHARMACOLOGY;

BACTERIA (MICROORGANISMS);

ACETATES; ANIMALS; BUTYRATES; CARRIER PROTEINS; COLITIS; COLON; DIETARY FIBER; FATTY ACIDS, VOLATILE; FERMENTATION; GASTROINTESTINAL MICROBIOME; HOMEOSTASIS; INFLAMMASOMES; MICE; MICE, KNOCKOUT; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NICOTINIC;

EID: 84926367699     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7734     Document Type: Article

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