-
1
-
-
27944459717
-
SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation
-
Ahuja D, Saenz-Robles MT, Pipas JM. 2005. SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation. Oncogene 24: 7729-7745.
-
(2005)
Oncogene
, vol.24
, pp. 7729-7745
-
-
Ahuja, D.1
Saenz-Robles, M.T.2
Pipas, J.M.3
-
2
-
-
78651162036
-
Acetylation and methylation of histones and their possible role in the regulation of Rna synthesis
-
Allfrey VG, Faulkner R, Mirsky AE. 1964. Acetylation and methylation of histones and their possible role in the regulation of Rna synthesis. Proc Natl Acad Sci 51: 786-794.
-
(1964)
Proc Natl Acad Sci
, vol.51
, pp. 786-794
-
-
Allfrey, V.G.1
Faulkner, R.2
Mirsky, A.E.3
-
3
-
-
22844432021
-
Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: A novel basis for antileukemia activity of histone deacetylase inhibitors
-
Bali P, Pranpat M, Bradner J, Balasis M, Fiskus W, Guo F, Rocha K, Kumaraswamy S, Boyapalle S, Atadja P, et al. 2005. Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: A novel basis for antileukemia activity of histone deacetylase inhibitors. J Biol Chem 280: 26729-26734.
-
(2005)
J Biol Chem
, vol.280
, pp. 26729-26734
-
-
Bali, P.1
Pranpat, M.2
Bradner, J.3
Balasis, M.4
Fiskus, W.5
Guo, F.6
Rocha, K.7
Kumaraswamy, S.8
Boyapalle, S.9
Atadja, P.10
-
4
-
-
34249299791
-
The complex language of chromatin regulation during transcription
-
Berger SL. 2007. The complex language of chromatin regulation during transcription. Nature 447: 407-412.
-
(2007)
Nature
, vol.447
, pp. 407-412
-
-
Berger, S.L.1
-
5
-
-
38849187293
-
CDK inhibitors: Cell cycle regulators and beyond
-
Besson A, Dowdy SF, Roberts JM. 2008. CDK inhibitors: Cell cycle regulators and beyond. Dev Cell 14: 159-169.
-
(2008)
Dev Cell
, vol.14
, pp. 159-169
-
-
Besson, A.1
Dowdy, S.F.2
Roberts, J.M.3
-
6
-
-
65549123471
-
HDAC2 negatively regulates memory formation and synaptic plasticity
-
Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, et al. 2009. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 459: 55-60.
-
(2009)
Nature
, vol.459
, pp. 55-60
-
-
Guan, J.S.1
Haggarty, S.J.2
Giacometti, E.3
Dannenberg, J.H.4
Joseph, N.5
Gao, J.6
Nieland, T.J.7
Zhou, Y.8
Wang, X.9
Mazitschek, R.10
-
7
-
-
66049146095
-
Genetic dissection of histone deacetylase requirement in tumor cells
-
Haberland M, Johnson A, Mokalled MH, Montgomery RL, Olson EN. 2009. Genetic dissection of histone deacetylase requirement in tumor cells. Proc Natl Acad Sci 106: 7751-7755.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 7751-7755
-
-
Haberland, M.1
Johnson, A.2
Mokalled, M.H.3
Montgomery, R.L.4
Olson, E.N.5
-
8
-
-
33748774926
-
Testing gene function early in the B cell lineage in mb1-cremice
-
Hobeika E, Thiemann S, Storch B, Jumaa H, Nielsen PJ, Pelanda R, Reth M. 2006. Testing gene function early in the B cell lineage in mb1-cremice. Proc Natl Acad Sci 103: 13789-13794.
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 13789-13794
-
-
Hobeika, E.1
Thiemann, S.2
Storch, B.3
Jumaa, H.4
Nielsen, P.J.5
Pelanda, R.6
Reth, M.7
-
9
-
-
0037161744
-
HDAC6 is a microtubule-associated deacetylase
-
Hubbert C, Guardiola A, Shao R, Kawaguchi Y, Ito A, Nixon A, Yoshida M, Wang XF, Yao TP. 2002. HDAC6 is a microtubule-associated deacetylase. Nature 417: 455-458.
-
(2002)
Nature
, vol.417
, pp. 455-458
-
-
Hubbert, C.1
Guardiola, A.2
Shao, R.3
Kawaguchi, Y.4
Ito, A.5
Nixon, A.6
Yoshida, M.7
Wang, X.F.8
Yao, T.P.9
-
10
-
-
0027938209
-
Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age
-
Hunter T, Pines J. 1994. Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. Cell 79: 573-582.
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
11
-
-
0033571243
-
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases
-
Indra AK, Warot X, Brocard J, Bornert JM, Xiao JH, Chambon P, Metzger D. 1999. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res 27: 4324-4327.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 4324-4327
-
-
Indra, A.K.1
Warot, X.2
Brocard, J.3
Bornert, J.M.4
Xiao, J.H.5
Chambon, P.6
Metzger, D.7
-
12
-
-
21144444486
-
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor
-
Kovacs JJ, Murphy PJ, Gaillard S, Zhao X, Wu JT, Nicchitta CV, Yoshida M, Toft DO, Pratt WB, Yao TP. 2005. HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor. Mol Cell 18: 601-607.
-
(2005)
Mol Cell
, vol.18
, pp. 601-607
-
-
Kovacs, J.J.1
Murphy, P.J.2
Gaillard, S.3
Zhao, X.4
Wu, J.T.5
Nicchitta, C.V.6
Yoshida, M.7
Toft, D.O.8
Pratt, W.B.9
Yao, T.P.10
-
13
-
-
0036649756
-
Genome-wide binding map of the histone deacetylase Rpd3 in yeast
-
Kurdistani SK, Robyr D, Tavazoie S, Grunstein M. 2002. Genome-wide binding map of the histone deacetylase Rpd3 in yeast. Nat Genet 31: 248-254.
-
(2002)
Nat Genet
, vol.31
, pp. 248-254
-
-
Kurdistani, S.K.1
Robyr, D.2
Tavazoie, S.3
Grunstein, M.4
-
14
-
-
2942518343
-
Mapping global histone acetylation patterns to gene expression
-
Kurdistani SK, Tavazoie S, Grunstein M. 2004. Mapping global histone acetylation patterns to gene expression. Cell 117: 721-733.
-
(2004)
Cell
, vol.117
, pp. 721-733
-
-
Kurdistani, S.K.1
Tavazoie, S.2
Grunstein, M.3
-
15
-
-
44649186791
-
Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development
-
Kwon K, Hutter C, Sun Q, Bilic I, Cobaleda C, Malin S, Busslinger M. 2008. Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development. Immunity 28: 751-762.
-
(2008)
Immunity
, vol.28
, pp. 751-762
-
-
Kwon, K.1
Hutter, C.2
Sun, Q.3
Bilic, I.4
Cobaleda, C.5
Malin, S.6
Busslinger, M.7
-
16
-
-
18444414332
-
Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
-
Lagger G, O'Carroll D, Rembold M, Khier H, Tischler J, Weitzer G, Schuettengruber B, Hauser C, Brunmeir R, Jenuwein T, et al. 2002. Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression. EMBO J 21: 2672-2681.
-
(2002)
EMBO J
, vol.21
, pp. 2672-2681
-
-
Lagger, G.1
O'Carroll, D.2
Rembold, M.3
Khier, H.4
Tischler, J.5
Weitzer, G.6
Schuettengruber, B.7
Hauser, C.8
Brunmeir, R.9
Jenuwein, T.10
-
17
-
-
0037383786
-
The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene
-
Lagger G, Doetzlhofer A, Schuettengruber B, Haidweger E, Simboeck E, Tischler J, Chiocca S, Suske G, Rotheneder H, Wintersberger E, et al. 2003. The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene. Mol Cell Biol 23: 2669-2679.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2669-2679
-
-
Lagger, G.1
Doetzlhofer, A.2
Schuettengruber, B.3
Haidweger, E.4
Simboeck, E.5
Tischler, J.6
Chiocca, S.7
Suske, G.8
Rotheneder, H.9
Wintersberger, E.10
-
18
-
-
42049088710
-
Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2
-
Lin YC, Lin JH, Chou CW, Chang YF, Yeh SH, Chen CC. 2008. Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2. Cancer Res 68: 2375-2383.
-
(2008)
Cancer Res
, vol.68
, pp. 2375-2383
-
-
Lin, Y.C.1
Lin, J.H.2
Chou, C.W.3
Chang, Y.F.4
Yeh, S.H.5
Chen, C.C.6
-
19
-
-
0034676439
-
Deacetylation of p53 modulates its effect on cell growth and apoptosis
-
Luo J, Su F, Chen D, Shiloh A, Gu W. 2000. Deacetylation of p53 modulates its effect on cell growth and apoptosis. Nature 408: 377-381.
-
(2000)
Nature
, vol.408
, pp. 377-381
-
-
Luo, J.1
Su, F.2
Chen, D.3
Shiloh, A.4
Gu, W.5
-
20
-
-
0033790450
-
Genetic analysis of mammalian cyclin-dependent kinases and their inhibitors
-
Malumbres M, Ortega S, Barbacid M. 2000. Genetic analysis of mammalian cyclin-dependent kinases and their inhibitors. Biol Chem 381: 827-838.
-
(2000)
Biol Chem
, vol.381
, pp. 827-838
-
-
Malumbres, M.1
Ortega, S.2
Barbacid, M.3
-
21
-
-
20644461729
-
Transcriptional networks in developing and mature B cells
-
Matthias P, Rolink AG. 2005. Transcriptional networks in developing and mature B cells. Nat Rev Immunol 5: 497-508.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 497-508
-
-
Matthias, P.1
Rolink, A.G.2
-
23
-
-
30344477367
-
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
-
Minucci S, Pelicci PG. 2006. Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nat Rev Cancer 6: 38-51.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 38-51
-
-
Minucci, S.1
Pelicci, P.G.2
-
24
-
-
34447511648
-
Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility
-
Montgomery RL, Davis CA, Potthoff MJ, Haberland M, Fielitz J, Qi X, Hill JA, Richardson JA, Olson EN. 2007. Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. Genes & Dev 21: 1790-1802.
-
(2007)
Genes & Dev
, vol.21
, pp. 1790-1802
-
-
Montgomery, R.L.1
Davis, C.A.2
Potthoff, M.J.3
Haberland, M.4
Fielitz, J.5
Qi, X.6
Hill, J.A.7
Richardson, J.A.8
Olson, E.N.9
-
25
-
-
66049101024
-
Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development
-
Montgomery RL, Hsieh J, Barbosa AC, Richardson JA, Olson EN. 2009. Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development. Proc Natl Acad Sci 106: 7876-7881.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 7876-7881
-
-
Montgomery, R.L.1
Hsieh, J.2
Barbosa, A.C.3
Richardson, J.A.4
Olson, E.N.5
-
26
-
-
14644406272
-
Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping
-
Roh TY, Cuddapah S, Zhao K. 2005. Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping. Genes & Dev 19: 542-552.
-
(2005)
Genes & Dev
, vol.19
, pp. 542-552
-
-
Roh, T.Y.1
Cuddapah, S.2
Zhao, K.3
-
27
-
-
0027269541
-
Changes in frequencies of clonable pre B cells during life in different lymphoid organs of mice
-
Rolink A, Haasner D, Nishikawa S, Melchers F. 1993. Changes in frequencies of clonable pre B cells during life in different lymphoid organs of mice. Blood 81: 2290-2300.
-
(1993)
Blood
, vol.81
, pp. 2290-2300
-
-
Rolink, A.1
Haasner, D.2
Nishikawa, S.3
Melchers, F.4
-
28
-
-
0033945861
-
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
-
Rountree MR, Bachman KE, Baylin SB. 2000. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat Genet 25: 269-277.
-
(2000)
Nat Genet
, vol.25
, pp. 269-277
-
-
Rountree, M.R.1
Bachman, K.E.2
Baylin, S.B.3
-
29
-
-
34347339526
-
Role for histone deacetylase 1 in human tumor cell proliferation
-
Senese S, Zaragoza K, Minardi S, Muradore I, Ronzoni S, Passafaro A, Bernard L, Draetta GF, Alcalay M, Seiser C, et al. 2007. Role for histone deacetylase 1 in human tumor cell proliferation. Mol Cell Biol 27: 4784-4795.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4784-4795
-
-
Senese, S.1
Zaragoza, K.2
Minardi, S.3
Muradore, I.4
Ronzoni, S.5
Passafaro, A.6
Bernard, L.7
Draetta, G.F.8
Alcalay, M.9
Seiser, C.10
-
30
-
-
35148826938
-
Shaping genetic alterations in human cancer: The p53 mutation paradigm
-
Soussi T, Wiman KG. 2007. Shaping genetic alterations in human cancer: The p53 mutation paradigm. Cancer Cell 12: 303-312.
-
(2007)
Cancer Cell
, vol.12
, pp. 303-312
-
-
Soussi, T.1
Wiman, K.G.2
-
31
-
-
0035917322
-
Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1
-
Taplick J, Kurtev V, Kroboth K, Posch M, Lechner T, Seiser C. 2001. Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1. J Mol Biol 308: 27-38.
-
(2001)
J Mol Biol
, vol.308
, pp. 27-38
-
-
Taplick, J.1
Kurtev, V.2
Kroboth, K.3
Posch, M.4
Lechner, T.5
Seiser, C.6
-
32
-
-
33847695362
-
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3b activity
-
Trivedi CM, Luo Y, Yin Z, Zhang M, Zhu W, Wang T, Floss T, Goettlicher M, Noppinger PR, Wurst W, et al. 2007. Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3b activity. Nat Med 13: 324-331.
-
(2007)
Nat Med
, vol.13
, pp. 324-331
-
-
Trivedi, C.M.1
Luo, Y.2
Yin, Z.3
Zhang, M.4
Zhu, W.5
Wang, T.6
Floss, T.7
Goettlicher, M.8
Noppinger, P.R.9
Wurst, W.10
-
33
-
-
0034707037
-
Global histone acetylation and deacetylation in yeast
-
Vogelauer M, Wu J, Suka N, Grunstein M. 2000. Global histone acetylation and deacetylation in yeast. Nature 408: 495-498.
-
(2000)
Nature
, vol.408
, pp. 495-498
-
-
Vogelauer, M.1
Wu, J.2
Suka, N.3
Grunstein, M.4
-
34
-
-
69449102464
-
Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes
-
Wang Z, Zang C, Cui K, Schones DE, Barski A, Peng W, Zhao K. 2009. Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell 138: 1019-1031.
-
(2009)
Cell
, vol.138
, pp. 1019-1031
-
-
Wang, Z.1
Zang, C.2
Cui, K.3
Schones, D.E.4
Barski, A.5
Peng, W.6
Zhao, K.7
-
35
-
-
0347628818
-
p21Waf1/Cip1 as a therapeutic target in breast and other cancers
-
Weiss RH. 2003. p21Waf1/Cip1 as a therapeutic target in breast and other cancers. Cancer Cell 4: 425-429.
-
(2003)
Cancer Cell
, vol.4
, pp. 425-429
-
-
Weiss, R.H.1
-
36
-
-
0025153163
-
New fluorescent dyes for lymphocyte migration studies. Analysis by flow cytometry and fluorescence microscopy
-
Weston SA, Parish CR. 1990. New fluorescent dyes for lymphocyte migration studies. Analysis by flow cytometry and fluorescence microscopy. J Immunol Methods 133: 87-97.
-
(1990)
J Immunol Methods
, vol.133
, pp. 87-97
-
-
Weston, S.A.1
Parish, C.R.2
-
37
-
-
39749127166
-
The Rpd3/Hda1 family of lysine deacetylases: From bacteria and yeast to mice and men
-
Yang XJ, Seto E. 2008. The Rpd3/Hda1 family of lysine deacetylases: From bacteria and yeast to mice and men. Nat Rev Mol Cell Biol 9: 206-218.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 206-218
-
-
Yang, X.J.1
Seto, E.2
-
38
-
-
34848901685
-
The p53 mutation 'gradient effect' and its clinical implications
-
Zambetti GP. 2007. The p53 mutation 'gradient effect' and its clinical implications. J Cell Physiol 213: 370-373.
-
(2007)
J Cell Physiol
, vol.213
, pp. 370-373
-
-
Zambetti, G.P.1
-
39
-
-
0037416151
-
HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo
-
Zhang Y, Li N, Caron C, Matthias G, Hess D, Khochbin S, Matthias P. 2003. HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo. EMBO J 22: 1168-1179.
-
(2003)
EMBO J
, vol.22
, pp. 1168-1179
-
-
Zhang, Y.1
Li, N.2
Caron, C.3
Matthias, G.4
Hess, D.5
Khochbin, S.6
Matthias, P.7
-
40
-
-
40749161986
-
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally
-
Zhang Y, Kwon S, Yamaguchi T, Cubizolles F, Rousseaux S, Kneissel M, Cao C, Li N, Cheng HL, Chua K, et al. 2008. Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally. Mol Cell Biol 28: 1688-1701.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1688-1701
-
-
Zhang, Y.1
Kwon, S.2
Yamaguchi, T.3
Cubizolles, F.4
Rousseaux, S.5
Kneissel, M.6
Cao, C.7
Li, N.8
Cheng, H.L.9
Chua, K.10
-
41
-
-
35148885660
-
Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice
-
Zimmermann S, Kiefer F, Prudenziati M, Spiller C, Hansen J, Floss T, Wurst W, Minucci S, Gottlicher M. 2007. Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice. Cancer Res 67: 9047-9054.
-
(2007)
Cancer Res
, vol.67
, pp. 9047-9054
-
-
Zimmermann, S.1
Kiefer, F.2
Prudenziati, M.3
Spiller, C.4
Hansen, J.5
Floss, T.6
Wurst, W.7
Minucci, S.8
Gottlicher, M.9
-
42
-
-
33750324764
-
Negative and positive regulation of gene expression by mouse histone deacetylase 1
-
Zupkovitz G, Tischler J, Posch M, Sadzak I, Ramsauer K, Egger G, Grausenburger R, Schweifer N, Chiocca S, Decker T, et al. 2006. Negative and positive regulation of gene expression by mouse histone deacetylase 1. Mol Cell Biol 26: 7913-7928.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7913-7928
-
-
Zupkovitz, G.1
Tischler, J.2
Posch, M.3
Sadzak, I.4
Ramsauer, K.5
Egger, G.6
Grausenburger, R.7
Schweifer, N.8
Chiocca, S.9
Decker, T.10
-
43
-
-
76749159433
-
The cyclin dependent kinase inhibitor p21 is a crucial target for Histone deacetylase 1 as regulator of cellular proliferation
-
doi: 10.1128/MCB.01500-09
-
Zupkovitz G, Grausenburger R, Brunmeir R, Senese S, Tischler J, Jurkin J, Rembold M, Meunier D, Egger G, Lagger S, et al. 2009. The cyclin dependent kinase inhibitor p21 is a crucial target for Histone deacetylase 1 as regulator of cellular proliferation. Mol Cell Biol. doi: 10.1128/MCB.01500-09.
-
(2009)
Mol Cell Biol
-
-
Zupkovitz, G.1
Grausenburger, R.2
Brunmeir, R.3
Senese, S.4
Tischler, J.5
Jurkin, J.6
Rembold, M.7
Meunier, D.8
Egger, G.9
Lagger, S.10
|