-
1
-
-
0025726702
-
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations
-
Jacob, J., Kassir, R. & Kelsoe, G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. J. Exp. Med. 173, 1165-1175 (1991).
-
(1991)
J. Exp. Med
, vol.173
, pp. 1165-1175
-
-
Jacob, J.1
Kassir, R.2
Kelsoe, G.3
-
2
-
-
0025951891
-
Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens
-
Liu, Y. J., Zhang, J., Lane, P. J., Chan, E. Y. & MacLennan, I. C. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur. J. Immunol. 21, 2951-2962 (1991).
-
(1991)
Eur. J. Immunol
, vol.21
, pp. 2951-2962
-
-
Liu, Y.J.1
Zhang, J.2
Lane, P.J.3
Chan, E.Y.4
Maclennan, I.C.5
-
3
-
-
23844445862
-
Two waves of memory B-cell generation in the primary immune response
-
Inamine, A. et al. Two waves of memory B-cell generation in the primary immune response. Int. Immunol. 17, 581-589 (2005).
-
(2005)
Int. Immunol
, vol.17
, pp. 581-589
-
-
Inamine, A.1
-
4
-
-
0022975140
-
Distinct short-lived and long-lived antibody-producing cell populations
-
Ho, F., Lortan, J. E., MacLennan, I. C. & Khan, M. Distinct short-lived and long-lived antibody-producing cell populations. Eur. J. Immunol. 16, 1297-1301 (1986).
-
(1986)
Eur. J. Immunol
, vol.16
, pp. 1297-1301
-
-
Ho, F.1
Lortan, J.E.2
Maclennan, I.C.3
Khan, M.4
-
5
-
-
0021679848
-
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation
-
Tsujimoto, Y., Finger, L. R., Yunis, J., Nowell, P. C. & Croce, C. M. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 226, 1097-1099 (1984).
-
(1984)
Science
, vol.226
, pp. 1097-1099
-
-
Tsujimoto, Y.1
Finger, L.R.2
Yunis, J.3
Nowell, P.C.4
Croce, C.M.5
-
6
-
-
0000538165
-
Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells
-
Dalla-Favera, R. et al. Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Proc. Natl Acad. Sci. USA 79, 7824-7827 (1982).
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 7824-7827
-
-
Dalla-Favera, R.1
-
7
-
-
0001292985
-
Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells
-
Taub, R. et al. Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc. Natl Acad. Sci. USA 79, 7837-7841 (1982).
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 7837-7841
-
-
Taub, R.1
-
8
-
-
0027495491
-
Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma
-
Ye, B. H. et al. Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma. Science 262, 747-750 (1993).
-
(1993)
Science
, vol.262
, pp. 747-750
-
-
Ye, B.H.1
-
9
-
-
0029086993
-
Self-tolerance checkpoints in B lymphocyte development
-
Goodnow, C. C. et al. Self-tolerance checkpoints in B lymphocyte development. Adv. Immunol. 59, 279-368 (1995).
-
(1995)
Adv. Immunol
, vol.59
, pp. 279-368
-
-
Goodnow, C.C.1
-
10
-
-
25444476976
-
B cell abnormality and autoimmune disorders
-
Tsubata, T. B cell abnormality and autoimmune disorders. Autoimmunity 38, 331-337 (2005).
-
(2005)
Autoimmunity
, vol.38
, pp. 331-337
-
-
Tsubata, T.1
-
12
-
-
79958254628
-
Epigenetic control of lymphocyte differentiation
-
Lopez-Granados, E. Epigenetic control of lymphocyte differentiation. Adv. Exp. Med. Biol. 711, 26-35 (2011).
-
(2011)
Adv. Exp. Med. Biol
, vol.711
, pp. 26-35
-
-
Lopez-Granados, E.1
-
13
-
-
58849092225
-
Epigenetic control of T-helper-cell differentiation
-
Wilson, C. B., Rowell, E. & Sekimata, M. Epigenetic control of T-helper-cell differentiation. Nat. Rev. Immunol. 9, 91-105 (2009).
-
(2009)
Nat. Rev. Immunol
, vol.9
, pp. 91-105
-
-
Wilson, C.B.1
Rowell, E.2
Sekimata, M.3
-
14
-
-
18444414332
-
Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
-
Lagger, G. et al. Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression. EMBO J. 21, 2672-2681 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 2672-2681
-
-
Lagger, G.1
-
15
-
-
77955425859
-
Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis
-
Wilting, R. H. et al. Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis. EMBO J. 29, 2586-2597 (2010).
-
(2010)
EMBO J.
, vol.29
, pp. 2586-2597
-
-
Wilting, R.H.1
-
16
-
-
77649115437
-
Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression
-
Yamaguchi, T. et al. Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression. Genes Dev. 24, 455-469 (2010).
-
(2010)
Genes Dev
, vol.24
, pp. 455-469
-
-
Yamaguchi, T.1
-
17
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
Bolden, J. E., Peart, M. J. & Johnstone, R. W. Anticancer activities of histone deacetylase inhibitors. Nat. Rev. Drug Discov. 5, 769-784 (2006).
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 769-784
-
-
Bolden, J.E.1
Peart, M.J.2
Johnstone, R.W.3
-
18
-
-
78651352243
-
Histone deacetylase inhibitors: Potential targets responsible for their anti-cancer effect
-
Dickinson, M., Johnstone, R. W. & Prince, H. M. Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect. Invest. New Drugs 28(Suppl 1): S3-S20 (2010).
-
(2010)
Invest. New Drugs
, vol.28
, pp. S3-S20
-
-
Dickinson, M.1
Johnstone, R.W.2
Prince, H.M.3
-
19
-
-
84864040412
-
Drug response in a genetically engineered mouse model of multiple myeloma is predictive of clinical efficacy
-
Chesi, M. et al. Drug response in a genetically engineered mouse model of multiple myeloma is predictive of clinical efficacy. Blood 120, 376-385 (2012).
-
(2012)
Blood
, vol.120
, pp. 376-385
-
-
Chesi, M.1
-
20
-
-
34249941680
-
Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma
-
Lindemann, R. K. et al. Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma. Proc. Natl Acad. Sci. USA 104, 8071-8076 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 8071-8076
-
-
Lindemann, R.K.1
-
21
-
-
3042566927
-
The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses
-
Moreira, J. M., Scheipers, P. & Sorensen, P. The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses. BMC Cancer 3, 30 (2003).
-
(2003)
BMC Cancer
, vol.3
, pp. 30
-
-
Moreira, J.M.1
Scheipers, P.2
Sorensen, P.3
-
22
-
-
84891276397
-
An intact immune system is required for the anti-cancer activities of histone deacetylase inhibitors
-
West, A. C. et al. An intact immune system is required for the anti-cancer activities of histone deacetylase inhibitors. Cancer Res. 73, 7265-7276 (2013).
-
(2013)
Cancer Res
, vol.73
, pp. 7265-7276
-
-
West, A.C.1
-
23
-
-
35948980739
-
Deacetylase inhibition promotes the generation and function of regulatory T cells
-
Tao, R. et al. Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat. Med. 13, 1299-1307 (2007).
-
(2007)
Nat. Med
, vol.13
, pp. 1299-1307
-
-
Tao, R.1
-
24
-
-
15444377542
-
Histone deacetylase inhibitor Trichostatin A reduces anti-DNA autoantibody production and represses IgH gene transcription
-
Lu, Z. P., Ju, Z. L., Shi, G. Y., Zhang, J. W. & Sun, J. Histone deacetylase inhibitor Trichostatin A reduces anti-DNA autoantibody production and represses IgH gene transcription. Biochem. Biophys. Res. Commun. 330, 204-209 (2005).
-
(2005)
Biochem. Biophys. Res. Commun
, vol.330
, pp. 204-209
-
-
Lu, Z.P.1
Ju, Z.L.2
Shi, G.Y.3
Zhang, J.W.4
Sun, J.5
-
25
-
-
0037330279
-
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse
-
Mishra, N., Reilly, C. M., Brown, D. R., Ruiz, P. & Gilkeson, G. S. Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse. J. Clin. Invest. 111, 539-552 (2003).
-
(2003)
J. Clin. Invest
, vol.111
, pp. 539-552
-
-
Mishra, N.1
Reilly, C.M.2
Brown, D.R.3
Ruiz, P.4
Gilkeson, G.S.5
-
26
-
-
84855448173
-
HDAC inhibitors: Modulating leukocyte differentiation, survival, proliferation and inflammation
-
Sweet, M. J., Shakespear, M. R., Kamal, N. A. & Fairlie, D. P. HDAC inhibitors: modulating leukocyte differentiation, survival, proliferation and inflammation. Immunol. Cell. Biol. 90, 14-22 (2012).
-
(2012)
Immunol. Cell. Biol
, vol.90
, pp. 14-22
-
-
Sweet, M.J.1
Shakespear, M.R.2
Kamal, N.A.3
Fairlie, D.P.4
-
27
-
-
79957932169
-
HDAC inhibition in lupus models
-
Reilly, C. M., Regna, N. & Mishra, N. HDAC inhibition in lupus models. Mol. Med. 17, 417-425 (2011).
-
(2011)
Mol. Med
, vol.17
, pp. 417-425
-
-
Reilly, C.M.1
Regna, N.2
Mishra, N.3
-
28
-
-
84859492923
-
HDAC inhibitor therapy in autoimmunity and transplantation
-
Hancock, W. W., Akimova, T., Beier, U. H., Liu, Y. & Wang, L. HDAC inhibitor therapy in autoimmunity and transplantation. Ann. Rheum. Dis. 71(Suppl 2): i46-i54 (2012).
-
(2012)
Ann. Rheum. Dis
, vol.71
, pp. i46-i54
-
-
Hancock, W.W.1
Akimova, T.2
Beier, U.H.3
Liu, Y.4
Wang, L.5
-
29
-
-
37649019847
-
Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data
-
Hawkins, E. D. et al. Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data. Nat. Protoc. 2, 2057-2067 (2007).
-
(2007)
Nat. Protoc
, vol.2
, pp. 2057-2067
-
-
Hawkins, E.D.1
-
30
-
-
33947238281
-
A model of immune regulation as a consequence of randomized lymphocyte division and death times
-
Hawkins, E. D., Turner, M. L., Dowling, M. R., van Gend, C. & Hodgkin, P. D. A model of immune regulation as a consequence of randomized lymphocyte division and death times. Proc. Natl Acad. Sci. USA 104, 5032-5037 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 5032-5037
-
-
Hawkins, E.D.1
Turner, M.L.2
Dowling, M.R.3
Van Gend, C.4
Hodgkin, P.D.5
-
31
-
-
84884156788
-
Quantal and graded stimulation of B lymphocytes as alternative strategies for regulating adaptive immune responses
-
Hawkins, E. D. et al. Quantal and graded stimulation of B lymphocytes as alternative strategies for regulating adaptive immune responses. Nat. Commun. 4, 2406 (2013).
-
(2013)
Nat. Commun
, vol.4
, pp. 2406
-
-
Hawkins, E.D.1
-
32
-
-
47949086920
-
Quantitative regulation of B cell division destiny by signal strength
-
Turner, M. L., Hawkins, E. D. & Hodgkin, P. D. Quantitative regulation of B cell division destiny by signal strength. J. Immunol. 181, 374-382 (2008).
-
(2008)
J. Immunol
, vol.181
, pp. 374-382
-
-
Turner, M.L.1
Hawkins, E.D.2
Hodgkin, P.D.3
-
33
-
-
0035054598
-
B cells activated via CD40 and IL-4 undergo a division burst but require continued stimulation to maintain division, survival and differentiation
-
Rush, J. S. & Hodgkin, P. D. B cells activated via CD40 and IL-4 undergo a division burst but require continued stimulation to maintain division, survival and differentiation. Eur. J. Immunol. 31, 1150-1159 (2001).
-
(2001)
Eur. J. Immunol
, vol.31
, pp. 1150-1159
-
-
Rush, J.S.1
Hodgkin, P.D.2
-
34
-
-
13444274622
-
Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
-
Insinga, A. et al. Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway. Nat. Med. 11, 71-76 (2005).
-
(2005)
Nat. Med
, vol.11
, pp. 71-76
-
-
Insinga, A.1
-
35
-
-
42449130607
-
HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen
-
Li, N. et al. HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen. Proc. Natl Acad. Sci. USA 105, 4796-4801 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 4796-4801
-
-
Li, N.1
-
36
-
-
84864020953
-
LBH589 enhances T cell activation in vivo and accelerates graft-versus-host disease in mice
-
e1181
-
Wang, D. et al. LBH589 enhances T cell activation in vivo and accelerates graft-versus-host disease in mice. Biol. Blood Marrow Transplant. 18, 1182-1190 e1181 (2012).
-
(2012)
Biol. Blood Marrow Transplant
, vol.18
, pp. 1182-1190
-
-
Wang, D.1
-
37
-
-
0026568919
-
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
-
Watanabe-Fukunaga, R., Brannan, C. I., Copeland, N. G., Jenkins, N. A. & Nagata, S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356, 314-317 (1992).
-
(1992)
Nature
, vol.356
, pp. 314-317
-
-
Watanabe-Fukunaga, R.1
Brannan, C.I.2
Copeland, N.G.3
Jenkins, N.A.4
Nagata, S.5
-
38
-
-
84884996251
-
Preclinical screening of histone deacetylase inhibitors combined with ABT-737, rhTRAIL/MD5-1 or 5-azacytidine using syngeneic Vk∗MYC multiple myeloma
-
Matthews, G. M. et al. Preclinical screening of histone deacetylase inhibitors combined with ABT-737, rhTRAIL/MD5-1 or 5-azacytidine using syngeneic Vk∗MYC multiple myeloma. Cell Death Dis. 4, e798 (2013).
-
(2013)
Cell Death Dis
, vol.4
, pp. e798
-
-
Matthews, G.M.1
-
39
-
-
84884699420
-
PANORAMA 2: Panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomibrefractory myeloma
-
Richardson, P. G. et al. PANORAMA 2: panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomibrefractory myeloma. Blood 122, 2331-2337 (2013).
-
(2013)
Blood
, vol.122
, pp. 2331-2337
-
-
Richardson, P.G.1
-
40
-
-
12444331082
-
Lyn tyrosine kinase: Accentuating the positive and the negative
-
Xu, Y., Harder, K. W., Huntington, N. D., Hibbs, M. L. & Tarlinton, D. M. Lyn tyrosine kinase: accentuating the positive and the negative. Immunity 22, 9-18 (2005).
-
(2005)
Immunity
, vol.22
, pp. 9-18
-
-
Xu, Y.1
Harder, K.W.2
Huntington, N.D.3
Hibbs, M.L.4
Tarlinton, D.M.5
-
41
-
-
0030740148
-
Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation
-
Chan, V. W., Meng, F., Soriano, P., DeFranco, A. L. & Lowell, C. A. Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation. Immunity 7, 69-81 (1997).
-
(1997)
Immunity
, vol.7
, pp. 69-81
-
-
Chan, V.W.1
Meng, F.2
Soriano, P.3
Defranco, A.L.4
Lowell, C.A.5
-
42
-
-
0028784215
-
Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease
-
Hibbs, M. L. et al. Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease. Cell 83, 301-311 (1995).
-
(1995)
Cell
, vol.83
, pp. 301-311
-
-
Hibbs, M.L.1
-
43
-
-
0028806216
-
Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice
-
Nishizumi, H. et al. Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice. Immunity 3, 549-560 (1995).
-
(1995)
Immunity
, vol.3
, pp. 549-560
-
-
Nishizumi, H.1
-
44
-
-
77954649027
-
BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs
-
Carrington, E. M. et al. BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs. Proc. Natl Acad. Sci. USA 107, 10967-10971 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 10967-10971
-
-
Carrington, E.M.1
-
45
-
-
0034798017
-
Spontaneous formation of germinal centers in autoimmune mice
-
Luzina, I. G. et al. Spontaneous formation of germinal centers in autoimmune mice. J. Leukoc. Biol. 70, 578-584 (2001).
-
(2001)
J. Leukoc. Biol
, vol.70
, pp. 578-584
-
-
Luzina, I.G.1
-
46
-
-
62849120700
-
Using histone deacetylase inhibitors to enhance Foxp3(+) regulatory T-cell function and induce allograft tolerance
-
Wang, L., Tao, R. & Hancock, W. W. Using histone deacetylase inhibitors to enhance Foxp3(+) regulatory T-cell function and induce allograft tolerance. Immunol. Cell. Biol. 87, 195-202 (2009).
-
(2009)
Immunol. Cell. Biol
, vol.87
, pp. 195-202
-
-
Wang, L.1
Tao, R.2
Hancock, W.W.3
-
47
-
-
79952396960
-
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
-
Bantscheff, M. et al. Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat. Biotechnol. 29, 255-265 (2011).
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 255-265
-
-
Bantscheff, M.1
-
48
-
-
14844353574
-
Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors
-
Peart, M. J. et al. Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors. Proc. Natl Acad. Sci. USA 102, 3697-3702 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 3697-3702
-
-
Peart, M.J.1
-
49
-
-
49849103540
-
Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin
-
Newbold, A. et al. Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin. Mol. Cancer Ther. 7, 1066-1079 (2008).
-
(2008)
Mol. Cancer Ther
, vol.7
, pp. 1066-1079
-
-
Newbold, A.1
-
50
-
-
0242302583
-
The genetics of human systemic lupus erythematosus
-
Tsao, B. P. The genetics of human systemic lupus erythematosus. Trends Immunol. 24, 595-602 (2003).
-
(2003)
Trends Immunol
, vol.24
, pp. 595-602
-
-
Tsao, B.P.1
-
51
-
-
74849131972
-
Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial
-
Merrill, J. T. et al. Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial. Arthritis Rheum. 62, 222-233 (2010).
-
(2010)
Arthritis Rheum
, vol.62
, pp. 222-233
-
-
Merrill, J.T.1
-
52
-
-
84866184129
-
Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: The Lupus Nephritis Assessment with Rituximab study
-
Rovin, B. H. et al. Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study. Arthritis Rheum. 64, 1215-1226 (2012).
-
(2012)
Arthritis Rheum
, vol.64
, pp. 1215-1226
-
-
Rovin, B.H.1
-
53
-
-
84875978060
-
HDAC inhibitors induce tumor-cell-selective pro-apoptotic transcriptional responses
-
Bolden, J. E. et al. HDAC inhibitors induce tumor-cell-selective pro-apoptotic transcriptional responses. Cell Death Dis. 4, e519 (2013).
-
(2013)
Cell Death Dis
, vol.4
, pp. e519
-
-
Bolden, J.E.1
-
54
-
-
78449282121
-
Mcl-1 is essential for germinal center formation and B cell memory
-
Vikstrom, I. et al. Mcl-1 is essential for germinal center formation and B cell memory. Science 330, 1095-1099 (2010).
-
(2010)
Science
, vol.330
, pp. 1095-1099
-
-
Vikstrom, I.1
-
55
-
-
84881478015
-
Phase Ia/II, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies
-
Deangelo, D. J. et al. Phase Ia/II, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies. Leukemia 27, 1628-1636 (2013).
-
(2013)
Leukemia
, vol.27
, pp. 1628-1636
-
-
Deangelo, D.J.1
-
56
-
-
0025875259
-
Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease
-
Cohen, P. L. & Eisenberg, R. A. Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol. 9, 243-269 (1991).
-
(1991)
Annu. Rev. Immunol
, vol.9
, pp. 243-269
-
-
Cohen, P.L.1
Eisenberg, R.A.2
-
57
-
-
77949322552
-
Autoimmune disease in Lyn-deficient mice is dependent on an inflammatory environment established by IL-6
-
Tsantikos, E. et al. Autoimmune disease in Lyn-deficient mice is dependent on an inflammatory environment established by IL-6. J. Immunol. 184, 1348-1360 (2010).
-
(2010)
J. Immunol
, vol.184
, pp. 1348-1360
-
-
Tsantikos, E.1
-
58
-
-
0030925491
-
The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response
-
Smith, K. G., Light, A., Nossal, G. J. & Tarlinton, D. M. The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response. EMBO J. 16, 2996-3006 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 2996-3006
-
-
Smith, K.G.1
Light, A.2
Nossal, G.J.3
Tarlinton, D.M.4
-
59
-
-
0034614896
-
Bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells
-
Smith, K. G. et al. bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells. J. Exp. Med. 191, 475-484 (2000).
-
(2000)
J. Exp. Med
, vol.191
, pp. 475-484
-
-
Smith, K.G.1
-
60
-
-
84877760790
-
Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity
-
1801
-
Hawkins, E. D. et al. Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity. Nat. Commun. 4, 1801 (2013).
-
(2013)
Nat. Commun
, vol.4
-
-
Hawkins, E.D.1
-
61
-
-
0021153603
-
Diffuse proliferative lupus nephritis: Identification of specific pathologic features affecting renal outcome
-
Austin, III H. A. et al. Diffuse proliferative lupus nephritis: identification of specific pathologic features affecting renal outcome. Kidney Int. 25, 689-695 (1984).
-
(1984)
Kidney Int
, vol.25
, pp. 689-695
-
-
Austin, H.A.1
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