-
1
-
-
0015009308
-
Hemoglobin synthesis in murinevirus-induced leukemic cells in vitro: Stimulation of erythroid differentiation by dimethyl sulfoxide
-
Friend C, Scher W, Holland JG, Sato T. Hemoglobin synthesis in murinevirus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide. Proc Natl Acad Sci USA 1971; 68: 378-382.
-
(1971)
Proc Natl Acad Sci USA
, vol.68
, pp. 378-382
-
-
Friend, C.1
Scher, W.2
Holland, J.G.3
Sato, T.4
-
2
-
-
77954884940
-
Romidepsin: A new therapy for cutaneous T-cell lymphoma and a potential therapy for solid tumors
-
Grant C, Rahman F, Piekarz R, Peer C, Frye R, Robey RW et al. Romidepsin: A new therapy for cutaneous T-cell lymphoma and a potential therapy for solid tumors. Expert Rev Anticancer Ther 2010; 10: 997-1008.
-
(2010)
Expert Rev Anticancer Ther
, vol.10
, pp. 997-1008
-
-
Grant, C.1
Rahman, F.2
Piekarz, R.3
Peer, C.4
Frye, R.5
Robey, R.W.6
-
3
-
-
33846122993
-
Dimethyl sulfoxide to vorinostat: Development of this histone deacetylase inhibitor as an anticancer drug
-
DOI 10.1038/nbt1272, PII NBT1272
-
Marks PA, Breslow R. Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug. Nat Biotechnol 2007; 25: 84-90. (Pubitemid 46087907)
-
(2007)
Nature Biotechnology
, vol.25
, Issue.1
, pp. 84-90
-
-
Marks, P.A.1
Breslow, R.2
-
4
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
DOI 10.1038/nrd2133, PII NRD2133
-
Bolden JE, Peart MJ, Johnstone RW. Anticancer activities of histone deacetylase inhibitors. Nat Rev Drug Discov 2006; 5: 769-784. (Pubitemid 44348499)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.9
, pp. 769-784
-
-
Bolden, J.E.1
Peart, M.J.2
Johnstone, R.W.3
-
5
-
-
78651352243
-
Histone deacetylase inhibitors: Potential targets responsible for their anti-cancer effect
-
Dickinson M, Johnstone RW, Prince HM. Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect. Invest New Drugs 2010; 28(Suppl 1): S3-S20.
-
(2010)
Invest New Drugs
, vol.28
, Issue.SUPPL. 1
-
-
Dickinson, M.1
Johnstone, R.W.2
Prince, H.M.3
-
6
-
-
77955643796
-
The clinical development of histone deacetylase inhibitors as targeted anticancerdrugs
-
Marks PA. The clinical development of histone deacetylase inhibitors as targeted anticancerdrugs. Expert Opin Investig Drugs 2010; 19: 1049-1066.
-
(2010)
Expert Opin Investig Drugs
, vol.19
, pp. 1049-1066
-
-
Marks, P.A.1
-
7
-
-
79957951510
-
Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancer
-
Dinarello CA, Fossati G, Mascagni P. Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancer. Mol Med 2011; 17: 333-352.
-
(2011)
Mol Med
, vol.17
, pp. 333-352
-
-
Dinarello, C.A.1
Fossati, G.2
Mascagni, P.3
-
9
-
-
79959804516
-
Histone deacetylases as regulators of inflammation and immunity
-
Shakespear MR, Halili MA, Irvine KM, Fairlie DP, Sweet MJ. Histone deacetylases as regulators of inflammation and immunity. Trends Immunol 2011; 32: 335-343.
-
(2011)
Trends Immunol
, vol.32
, pp. 335-343
-
-
Shakespear, M.R.1
Halili, M.A.2
Irvine, K.M.3
Fairlie, D.P.4
Sweet, M.J.5
-
10
-
-
13444274622
-
Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
-
DOI 10.1038/nm1160
-
Insinga A, Monestiroli S, Ronzoni S, Gelmetti V, Marchesi F, Viale A et al. Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway. Nat Med 2005; 11: 71-76. (Pubitemid 40215840)
-
(2005)
Nature Medicine
, vol.11
, Issue.1
, pp. 71-76
-
-
Insinga, A.1
Monestiroli, S.2
Ronzoni, S.3
Gelmetti, V.4
Marchesi, F.5
Viale, A.6
Altucci, L.7
Nervi, C.8
Minucci, S.9
Pelicci, P.G.10
-
11
-
-
13444306459
-
Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells
-
DOI 10.1038/nm1161
-
Nebbioso A, Clarke N, Voltz E, Germain E, Ambrosino C, Bontempo P et al. Tumor-selectiveaction of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells. Nat Med 2005; 11: 77-84. (Pubitemid 40215841)
-
(2005)
Nature Medicine
, vol.11
, Issue.1
, pp. 77-84
-
-
Nebbioso, A.1
Clarke, N.2
Voltz, E.3
Germain, E.4
Ambrosino, C.5
Bontempo, P.6
Alvarez, R.7
Schiavone, E.M.8
Ferrara, F.9
Bresciani, F.10
Weisz, A.11
De Lera, A.R.12
Gronemeyer, H.13
Altucci, L.14
-
12
-
-
34249941680
-
Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma
-
DOI 10.1073/pnas.0702294104
-
Lindemann RK, Newbold A, Whitecross KF, Cluse LA, Frew AJ, Ellis L et al. Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma. Proc Natl Acad Sci USA 2007; 104: 8071-8076. (Pubitemid 47185877)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.19
, pp. 8071-8076
-
-
Lindemann, R.K.1
Newbold, A.2
Whitecross, K.F.3
Cluse, L.A.4
Frew, A.J.5
Ellis, L.6
Williams, S.7
Wiegmans, A.P.8
Dear, A.E.9
Scott, C.L.10
Pellegrini, M.11
Wei, A.12
Richon, V.M.13
Marks, P.A.14
Lowe, S.W.15
Smyth, M.J.16
Johnstone, R.W.17
-
13
-
-
0035845541
-
The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species
-
DOI 10.1073/pnas.191208598
-
Ruefli AA, Ausserlechner MJ, Bernhard D, Sutton VR, Tainton KM, Kofler R et al. The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species. Proc Natl Acad Sci USA 2001; 98: 10833-10838. (Pubitemid 32878706)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.19
, pp. 10833-10838
-
-
Ruefli, A.A.1
Ausserlechner, M.J.2
Bernhard, D.3
Sutton, V.R.4
Tainton, K.M.5
Kofler, R.6
Smyth, M.J.7
Johnstone, R.W.8
-
14
-
-
20044390016
-
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors
-
DOI 10.1073/pnas.0408732102
-
Ungerstedt JS, Sowa Y, Xu WS, Shao Y, Dokmanovic M, Perez G et al. Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors. Proc Natl Acad Sci U S A 2005; 102: 673-678. (Pubitemid 40282724)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.3
, pp. 673-678
-
-
Ungerstedt, J.S.1
Sowa, Y.2
Xu, W.-S.3
Shao, Y.4
Dokmanovic, M.5
Perez, G.6
Ngo, L.7
Holmgren, A.8
Jiang, X.9
Marks, P.A.10
-
15
-
-
77957958015
-
Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound beta-phenylethyl isothiocyanate
-
Hu Y, Lu W, Chen G, Zhang H, Jia Y, Wei Y et al. Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound beta-phenylethyl isothiocyanate. Blood 2010; 116: 2732-2741.
-
(2010)
Blood
, vol.116
, pp. 2732-2741
-
-
Hu, Y.1
Lu, W.2
Chen, G.3
Zhang, H.4
Jia, Y.5
Wei, Y.6
-
16
-
-
80051747278
-
Finally how histone deacetylase inhibitors disrupt mitosis
-
Gabrielli B, Chia K, Warrener R. Finally how histone deacetylase inhibitors disrupt mitosis!. Cell Cycle 2011; 10: 2658-26561.
-
(2011)
Cell Cycle
, vol.10
, pp. 2658-26561
-
-
Gabrielli, B.1
Chia, K.2
Warrener, R.3
-
17
-
-
0042704723
-
Tumor cell-selective cytotoxicity by targeting cell cycle checkpoints
-
Warrener R, Beamish H, Burgess A, Waterhouse NJ, Giles N, Fairlie D et al. Tumor cell-selective cytotoxicity by targeting cell cycle checkpoints. FASEB J 2003; 17: 1550-1552.
-
(2003)
FASEB J
, vol.17
, pp. 1550-1552
-
-
Warrener, R.1
Beamish, H.2
Burgess, A.3
Waterhouse, N.J.4
Giles, N.5
Fairlie, D.6
-
18
-
-
0032499756
-
P21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells
-
Archer SY, Meng S, Shei A, Hodin RA. p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells. Proc Natl Acad Sci USA 1998; 95: 6791-6796.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6791-6796
-
-
Archer, S.Y.1
Meng, S.2
Shei, A.3
Hodin, R.A.4
-
19
-
-
0033520944
-
Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects
-
Sambucetti LC, Fischer DD, Zabludoff S, Kwon PO, Chamberlin H, Trogani N et al. Histonedeacetylase inhibition selectivelyalterstheactivityand expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects. J Biol Chem 1999; 274: 34940-34947. (Pubitemid 129509542)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.49
, pp. 34940-34947
-
-
Sambucetti, L.C.1
Fischer, D.D.2
Zabludoff, S.3
Kwon, P.O.4
Chamberlin, H.5
Trogani, N.6
Xu, H.7
Cohen, D.8
-
20
-
-
4644304383
-
Histone deacetylase inhibitors specifically kill nonproliferating tumour cells
-
DOI 10.1038/sj.onc.1207893
-
Burgess A, Ruefli A, Beamish H, Warrener R, Saunders N, Johnstone R et al. Histone deacetylase inhibitors specifically kill nonproliferating tumour cells. Oncogene 2004; 23: 6693-6701. (Pubitemid 39280001)
-
(2004)
Oncogene
, vol.23
, Issue.40
, pp. 6693-6701
-
-
Burgess, A.1
Ruefli, A.2
Beamish, H.3
Warrener, R.4
Saunders, N.5
Johnstone, R.6
Gabrielli, B.7
-
21
-
-
0031569455
-
Lipopolysaccharide Induces Synthesis of Mouse Colony-Stimulating Factor-1 in Vivo
-
Roth P, Bartocci A, Stanley ER. Lipopolysaccharide induces synthesisof mousecolony-stimulatingfactor-1 in vivo. JImmunol1997; 158: 3874-3880. (Pubitemid 127488747)
-
(1997)
Journal of Immunology
, vol.158
, Issue.8
, pp. 3874-3880
-
-
Roth, P.1
Bartocci, A.2
Stanley, E.R.3
-
22
-
-
0033840205
-
The colony-stimulating factors and collagen-induced arthritis: Exacerbation of disease by M-CSF and G-CSF and require-ment for endogenous M-CSF
-
Campbell IK, Rich MJ, Bischof RJ, Hamilton JA. The colony-stimulating factors and collagen-induced arthritis: exacerbation of disease by M-CSF and G-CSF and require-ment for endogenous M-CSF. J Leukoc Biol 2000; 68: 144-150.
-
(2000)
J Leukoc Biol
, vol.68
, pp. 144-150
-
-
Campbell, I.K.1
Rich, M.J.2
Bischof, R.J.3
Hamilton, J.A.4
-
23
-
-
0037443657
-
Reduced macrophage recruitment, proliferation, and activation in colony-stimulating factor-1-deficient mice results in decreased tubular apoptosis during renal inflammation
-
Lenda DM, Kikawada E, Stanley ER, Kelley VR. Reduced macrophage recruitment, proliferation, and activation in colony-stimulating factor-1-deficient mice results in decreased tubular apoptosis during renal inflammation. J Immunol 2003; 170: 3254-3262. (Pubitemid 36302203)
-
(2003)
Journal of Immunology
, vol.170
, Issue.6
, pp. 3254-3262
-
-
Lenda, D.M.1
Kikawada, E.2
Stanley, E.R.3
Kelley, V.R.4
-
24
-
-
72049083750
-
Circulating CSF-1 promotes monocyte and macrophage phenotypes that enhance lupus nephritis
-
Menke J, Rabacal WA, Byrne KT, Iwata Y, Schwartz MM, Stanley ER et al. Circulating CSF-1 promotes monocyte and macrophage phenotypes that enhance lupus nephritis. JAm Soc Nephrol 2009; 20: 2581-2592.
-
(2009)
JAm Soc Nephrol
, vol.20
, pp. 2581-2592
-
-
Menke, J.1
Rabacal, W.A.2
Byrne, K.T.3
Iwata, Y.4
Schwartz, M.M.5
Stanley, E.R.6
-
25
-
-
0030969425
-
Role of macrophage colony-stimulating factor in atherosclerosis: Studies of osteopetrotic mice
-
Qiao JH, Tripathi J, Mishra NK, Cai Y, Tripathi S, Wang XP et al. Role of macrophage colony-stimulating factor in atherosclerosis: studies of osteopetrotic mice. Am J Pathol 1997; 150: 1687-1699. (Pubitemid 27193816)
-
(1997)
American Journal of Pathology
, vol.150
, Issue.5
, pp. 1687-1699
-
-
Qiao, J.-H.1
Tripathi, J.2
Mishra, N.K.3
Cai, Y.4
Tripathi, S.5
Wang, X.-P.6
Imes, S.7
Fishbein, M.C.8
Clinton, S.K.9
Libby, P.10
Lusis, A.J.11
Rajavashisth, T.B.12
-
26
-
-
0032525907
-
Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptor-deficient mice
-
Rajavashisth T, Qiao JH, Tripathi S, Tripathi J, Mishra N, Hua M et al. Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptor- deficient mice. J Clin Invest 1998; 101: 2702-2710. (Pubitemid 28294579)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.12
, pp. 2702-2710
-
-
Rajavashisth, T.1
Qiao, J.-H.2
Tripathi, S.3
Tripathi, J.4
Mishra, N.5
Hua, M.6
Wang, X.-P.7
Loussararian, A.8
Clinton, S.9
Libby, P.10
Lusis, A.11
-
27
-
-
0029146354
-
Increased resistance of CSF-1-deficient, macrophage-deficient, TNF alpha-deficient, and IL-1 alpha-deficient op/op mice to endotoxin
-
Szperl M, Ansari AA, Urbanowska E, Szwech P, Kalinski P, Wiktor-Jedrzejczak W. Increased resistance of CSF-1-deficient, macrophage-deficient, TNF alpha-deficient, and IL-1 alpha-deficient op/op mice to endotoxin. Ann N Y Acad Sci 1995; 762: 499-501.
-
(1995)
Ann N y Acad Sci
, vol.762
, pp. 499-501
-
-
Szperl, M.1
Ansari, A.A.2
Urbanowska, E.3
Szwech, P.4
Kalinski, P.5
Wiktor-Jedrzejczak, W.6
-
28
-
-
67650655975
-
Antibody blockade of c-fms suppresses the progression of inflammation and injury in early diabetic nephropathy in obese db/db mice
-
Lim AK, Ma FY, Nikolic-Paterson DJ, Thomas MC, Hurst LA, Tesch GH. Antibody blockade of c-fms suppresses the progression of inflammation and injury in early diabetic nephropathy in obese db/db mice. Diabetologia 2009; 52: 1669-1679.
-
(2009)
Diabetologia
, vol.52
, pp. 1669-1679
-
-
Lim, A.K.1
Ma, F.Y.2
Nikolic-Paterson, D.J.3
Thomas, M.C.4
Hurst, L.A.5
Tesch, G.H.6
-
29
-
-
46249090513
-
Colony-stimulating factors in inflammation and autoimmunity
-
DOI 10.1038/nri2356, PII NRI2356
-
Hamilton JA. Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol 2008; 8: 533-544. (Pubitemid 351913679)
-
(2008)
Nature Reviews Immunology
, vol.8
, Issue.7
, pp. 533-544
-
-
Hamilton, J.A.1
-
30
-
-
45749136367
-
Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl) oxy) benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats?
-
DOI 10.1124/jpet.107.129429
-
Conway JG, Pink H, Bergquist ML, Han B, Depee S, Tadepalli S et al. Effects of the c FMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy) benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats. JPharmacol Exp Ther 2008; 326: 41-50. (Pubitemid 351872132)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.326
, Issue.1
, pp. 41-50
-
-
Conway, J.G.1
Pink, H.2
Bergquist, M.L.3
Han, B.4
Depee, S.5
Tadepalli, S.6
Lin, P.7
Crumrine, R.C.8
Binz, J.9
Clark, R.L.10
Selph, J.L.11
Stimpson, S.A.12
Hutchins, J.T.13
Chamberlain, S.D.14
Brodie, T.A.15
-
31
-
-
0038542837
-
Two histone deacetylase inhibitors, trichostatin A and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages
-
DOI 10.1182/blood-2002-08-2622
-
Rahman MM, Kukita A, Kukita T, Shobuike T, Nakamura T, Kohashi O. Two histone deacetylase inhibitors, trichostatin A and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages. Blood 2003; 101: 3451-3459. (Pubitemid 36868944)
-
(2003)
Blood
, vol.101
, Issue.9
, pp. 3451-3459
-
-
Rahman, M.1
Kukita, A.2
Kukita, T.3
Shobuike, T.4
Nakamura, T.5
Kohashi, O.6
-
32
-
-
0037307026
-
A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse
-
DOI 10.1182/blood-2002-02-0569
-
Sasmono RT, Oceandy D, Pollard JW, Tong W, Pavli P, Wainwright BJ et al. A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood 2003; 101: 1155-1163. (Pubitemid 36139391)
-
(2003)
Blood
, vol.101
, Issue.3
, pp. 1155-1163
-
-
Sasmono, R.T.1
Oceandy, D.2
Pollard, J.W.3
Tong, W.4
Pavli, P.5
Wainwright, B.J.6
Ostrowski, M.C.7
Himes, S.R.8
Hume, D.A.9
-
33
-
-
27144487343
-
Inhibition of histone deacetylase suppresses osteoclastogenesis and bone destruction by inducing IFN-β production
-
Nakamura T, Kukita T, Shobuike T, Nagata K, Wu Z, Ogawa K et al. Inhibition of histone deacetylase suppresses osteoclastogenesis and bone destruction by inducing IFN-beta production. JImmunol 2005; 175: 5809-5816. (Pubitemid 41508065)
-
(2005)
Journal of Immunology
, vol.175
, Issue.9
, pp. 5809-5816
-
-
Nakamura, T.1
Kukita, T.2
Shobuike, T.3
Nagata, K.4
Wu, Z.5
Ogawa, K.6
Hotokebuchi, T.7
Kohashi, O.8
Kukita, A.9
-
34
-
-
33646851955
-
Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-κB activation
-
DOI 10.1074/jbc.M507213200
-
Takada Y, Gillenwater A, Ichikawa H, Aggarwal BB. Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappa B activation. J Biol Chem 2006; 281: 5612-5622. (Pubitemid 43847658)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.9
, pp. 5612-5622
-
-
Takada, Y.1
Gillenwater, A.2
Ichikawa, H.3
Aggarwal, B.B.4
-
35
-
-
80053165908
-
Inhibitors of histone deacetylases in class i and class II suppress human osteoclasts in vitro
-
Cantley MD, Fairlie DP, Bartold PM, Rainsford KD, Le GT, Lucke AJ et al. Inhibitors of histone deacetylases in class I and class II suppress human osteoclasts in vitro. J Cell Physiol 2011; 226: 3233-3241.
-
(2011)
J Cell Physiol
, vol.226
, pp. 3233-3241
-
-
Cantley, M.D.1
Fairlie, D.P.2
Bartold, P.M.3
Rainsford, K.D.4
Le, G.T.5
Lucke, A.J.6
-
36
-
-
79953330801
-
HDAC3 and HDAC7 have opposite effects on osteoclast differentiation
-
Pham L, Kaiser B, Romsa A, Schwarz T, Gopalakrishnan R, Jensen ED et al. HDAC3 and HDAC7 have opposite effects on osteoclast differentiation. J Biol Chem 2011; 286: 12056-12065.
-
(2011)
J Biol Chem
, vol.286
, pp. 12056-12065
-
-
Pham, L.1
Kaiser, B.2
Romsa, A.3
Schwarz, T.4
Gopalakrishnan, R.5
Jensen, E.D.6
-
37
-
-
33746499843
-
LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression
-
DOI 10.1096/fj.05-5360com
-
Aung HT, Schroder K, Himes SR, Brion K, van Zuylen W, Trieu A et al. LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression. FASEBJ 2006; 20: 1315-1327. (Pubitemid 44943839)
-
(2006)
FASEB Journal
, vol.20
, Issue.9
, pp. 1315-1327
-
-
Hnin, T.A.1
Schroder, K.2
Himes, S.R.3
Brion, K.4
Van Zuylen, W.5
Trieu, A.6
Suzuki, H.7
Hayashizaki, Y.8
Hume, D.A.9
Sweet, M.J.10
Ravasi, T.11
-
38
-
-
77954013043
-
Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS
-
Halili MA, Andrews MR, Labzin LI, Schroder K, Matthias G, Cao C et al. Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. J Leukoc Biol 2010; 87: 1103-1114.
-
(2010)
J Leukoc Biol
, vol.87
, pp. 1103-1114
-
-
Halili, M.A.1
Andrews, M.R.2
Labzin, L.I.3
Schroder, K.4
Matthias, G.5
Cao, C.6
-
39
-
-
0035500922
-
Loss of PU.1 Expression following inhibition of histone deacetylases
-
Laribee RN, Klemsz MJ. Loss of PU.1 expression following inhibition of histone deacetylases. J Immunol 2001; 167: 5160-5166. (Pubitemid 33009752)
-
(2001)
Journal of Immunology
, vol.167
, Issue.9
, pp. 5160-5166
-
-
Laribee, R.N.1
Klemsz, M.J.2
-
40
-
-
0032715353
-
Bacterial/Cp G DNA down-modulates colony stimulating factor-1 receptor surface expression on murine bone marrow-derived macrophages with concomitant growth arrest and fac-tor-independent survival
-
Sester DP, Beasley SJ, Sweet MJ, Fowles LF, Cronau SL, Stacey KJ et al. Bacterial/Cp G DNA down-modulates colony stimulating factor-1 receptor surface expression on murine bone marrow-derived macrophages with concomitant growth arrest and fac-tor-independent survival. J Immunol 1999; 163: 6541-6550.
-
(1999)
J Immunol
, vol.163
, pp. 6541-6550
-
-
Sester, D.P.1
Beasley Sweet, S.J.M.J.2
Fowles, L.F.3
Cronau, S.L.4
Stacey, K.J.5
-
41
-
-
0031878972
-
Synovial lining, endothelial and inflammatory mononuclear cell proliferation in synovial membranes in psoriatic and reactive arthritis: A comparative quantitative morphometric study
-
Ceponis A, Konttinen YT, Imai S, Tamulaitiene M, Li TF, Xu JW et al. Synovial lining, endothelial and inflammatory mononuclear cell proliferation in synovial membranes in psoriatic and reactive arthritis: A comparative quantitative morphometric study. Br J Rheumatol 1998; 37: 170-178.
-
(1998)
Br J Rheumatol
, vol.37
, pp. 170-178
-
-
Ceponis, A.1
Konttinen, Y.T.2
Imai, S.3
Tamulaitiene, M.4
Li, T.F.5
Xu, J.W.6
-
42
-
-
0028978776
-
Active proliferation of different cell types, including lympho-cytes, in human atherosclerotic plaques
-
Rekhter MD, Gordon D. Active proliferation of different cell types, including lympho-cytes, in human atherosclerotic plaques. Am J Pathol 1995; 147: 668-677.
-
(1995)
Am J Pathol
, vol.147
, pp. 668-677
-
-
Rekhter, M.D.1
Gordon, D.2
-
43
-
-
79958715229
-
Local macrophage proliferation, ratherthan recruitmentfrom theblood, isa signatureof TH2 inflammation
-
Jenkins SJ, Ruckerl D, Cook PC, Jones LH, Finkelman FD, van Rooijen N et al. Local macrophage proliferation, ratherthan recruitmentfrom theblood, isa signatureof TH2 inflammation. Science 2011; 332: 1284-1288.
-
(2011)
Science
, vol.332
, pp. 1284-1288
-
-
Jenkins, S.J.1
Ruckerl, D.2
Cook, P.C.3
Jones, L.H.4
Finkelman, F.D.5
Van Rooijen, N.6
-
44
-
-
77951925741
-
Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue
-
Grabiec AM, Krausz S, de Jager W, Burakowski T, Groot D, Sanders ME et al. Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue. J Immunol 2010; 184: 2718-2728.
-
(2010)
J Immunol
, vol.184
, pp. 2718-2728
-
-
Grabiec, A.M.1
Krausz, S.2
De Jager, W.3
Burakowski, T.4
Groot, D.5
Sanders, M.E.6
-
45
-
-
0034459567
-
Macrophages require constitutive NF-κB activation to maintain A1 expression and mitochondrial homeostasis
-
DOI 10.1128/MCB.20.23.8855-8865.2000
-
Pagliari LJ, Perlman H, Liu H, Pope RM. Macrophages require constitutive NF-kappa B activation to maintain A1 expression and mitochondrial homeostasis. Mol Cell Biol 2000; 20: 8855-8865. (Pubitemid 32245918)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.23
, pp. 8855-8865
-
-
Pagliari, L.J.1
Perlman, H.2
Liu, H.3
Pope, R.M.4
-
46
-
-
79952439646
-
Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress
-
Mercado N, Thimmulappa R, Thomas CM, Fenwick PS, Chana KK, Donnelly LE et al. Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress. Biochem Biophys Res Commun 2011; 406: 292-298.
-
(2011)
Biochem Biophys Res Commun
, vol.406
, pp. 292-298
-
-
Mercado, N.1
Thimmulappa, R.2
Thomas, C.M.3
Fenwick, P.S.4
Chana, K.K.5
Donnelly, L.E.6
-
47
-
-
0142179154
-
Identification of Novel Isoform-Selective Inhibitors within Class I Histone Deacetylases
-
DOI 10.1124/jpet.103.055541
-
Hu E, Dul E, Sung CM, Chen Z, Kirkpatrick R, Zhang GF et al. Identification of novel isoform-selective inhibitors within class I histone deacetylases. J Pharmacol Exp Ther 2003; 307: 720-728. (Pubitemid 37310689)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.307
, Issue.2
, pp. 720-728
-
-
Hu, E.1
Dul, E.2
Sung, C.-M.3
Chen, Z.4
Kirkpatrick, R.5
Zhang, G.-F.6
Johanson, K.7
Liu, R.8
Lago, A.9
Hofmann, G.10
Macarron, R.11
De Los Frailes, M.12
Perez, P.13
Krawiec, J.14
Winkler, J.15
Jaye, M.16
-
48
-
-
18444414332
-
Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
-
DOI 10.1093/emboj/21.11.2672
-
Lagger G, O'Carroll D, Rembold M, Khier H, Tischler J, Weitzer G et al. Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression. EMBOJ 2002; 21: 2672-2681. (Pubitemid 34619383)
-
(2002)
EMBO Journal
, vol.21
, Issue.11
, pp. 2672-2681
-
-
Lagger, G.1
O'Carroll, D.2
Rembold, M.3
Khier, H.4
Tischler, J.5
Weitzer, G.6
Schuettengruber, B.7
Hauser, C.8
Brunmeir, R.9
Jenuwein, T.10
Seiser, C.11
-
49
-
-
77955425859
-
Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoi-esis
-
Wilting RH, Yanover E, Heideman MR, Jacobs H, Horner J, van der Torre J et al. Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoi-esis. EMBOJ 2010; 29: 2586-2597.
-
(2010)
EMBOJ
, vol.29
, pp. 2586-2597
-
-
Wilting, R.H.1
Yanover, E.2
Heideman, M.R.3
Jacobs, H.4
Horner, J.5
Van Der Torre, J.6
-
50
-
-
77649115437
-
Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression
-
Yamaguchi T, Cubizolles F, Zhang Y, Reichert N, Kohler H, Seiser C et al. Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression. Genes Dev 2010; 24: 455-469.
-
(2010)
Genes Dev
, vol.24
, pp. 455-469
-
-
Yamaguchi, T.1
Cubizolles, F.2
Zhang, Y.3
Reichert, N.4
Kohler, H.5
Seiser, C.6
-
51
-
-
78651295381
-
HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells
-
Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P et al. HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells. Leukemia 2011; 25: 161-168.
-
(2011)
Leukemia
, vol.25
, pp. 161-168
-
-
Song Tai, W.Y.T.1
Tian, Z.2
Hideshima, T.3
Chauhan, D.4
Nanjappa, P.5
-
52
-
-
35948983828
-
Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment
-
DOI 10.1111/j.1365-2567.2007.02678.x
-
Bode KA, Schroder K, Hume DA, Ravasi T, Heeg K, Sweet MJ et al. Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. Immunology 2007; 122: 596-606. (Pubitemid 350075958)
-
(2007)
Immunology
, vol.122
, Issue.4
, pp. 596-606
-
-
Bode, K.A.1
Schroder, K.2
Hume, D.A.3
Ravasi, T.4
Heeg, K.5
Sweet, M.J.6
Dalpke, A.H.7
-
53
-
-
77349124906
-
Histone deacetylase inhibitors decrease the antigen presenting activity of murine bone marrow derived dendritic cells
-
Kim ES, Lee JK. Histone deacetylase inhibitors decrease the antigen presenting activity of murine bone marrow derived dendritic cells. Cell Immunol 2010; 262: 52-57.
-
(2010)
Cell Immunol
, vol.262
, pp. 52-57
-
-
Kim, E.S.1
Lee, J.K.2
-
54
-
-
79955961149
-
Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice
-
Misaki K, Morinobu A, Saegusa J, Kasagi S, Fujita M, Miyamoto Y et al. Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice. Arthritis Res Ther 2011; 13: R77.
-
(2011)
Arthritis Res Ther
, vol.13
-
-
Misaki, K.1
Morinobu, A.2
Saegusa, J.3
Kasagi, S.4
Fujita, M.5
Miyamoto, Y.6
-
55
-
-
33846876336
-
Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function
-
DOI 10.1182/blood-2006-04-019711
-
Brogdon JL, Xu Y, Szabo SJ, An S, Buxton F, Cohen D et al. Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function. Blood 2007; 109: 1123-1130. (Pubitemid 46220659)
-
(2007)
Blood
, vol.109
, Issue.3
, pp. 1123-1130
-
-
Brogdon, J.L.1
Xu, Y.2
Szabo, S.J.3
An, S.4
Buxton, F.5
Cohen, D.6
Huang, Q.7
-
56
-
-
77956237892
-
Blockade of dendritic cell development by bacterial fermentation products butyrate and propio-nate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases
-
Singh N, Thangaraju M, Prasad PD, Martin PM, Lambert NA, Boettger T et al. Blockade of dendritic cell development by bacterial fermentation products butyrate and propio-nate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases. J Biol Chem 2010; 285: 27601-27608.
-
(2010)
J Biol Chem
, vol.285
, pp. 27601-27608
-
-
Singh, N.1
Thangaraju, M.2
Prasad, P.D.3
Martin, P.M.4
Lambert, N.A.5
Boettger, T.6
-
57
-
-
79251598810
-
The short chain fatty acid sodium butyrate regulates the induction of CD1a in developingdendriticcells
-
Nascimento CR, Freire-de-Lima CG, da Silva de Oliveira A, Rumjanek FD, Rumjanek VM. The short chain fatty acid sodium butyrate regulates the induction of CD1a in developingdendriticcells. Immunobiology 2011; 216: 275-284.
-
(2011)
Immunobiology
, vol.216
, pp. 275-284
-
-
Nascimento, C.R.1
Freire-De-Lima, C.G.2
Da Silva De Oliveira, A.3
Rumjanek, F.D.4
Rumjanek, V.M.5
-
58
-
-
34447119505
-
Histone deacetylase inhibitors affect dendritic cell differentiation and immunogenicity
-
DOI 10.1158/1078-0432.CCR-06-2903
-
Nencioni A, Beck J, Werth D, Grunebach F, Patrone F, Ballestrero A et al. Histone deacetylase inhibitors affect dendritic cell differentiation and immunogenicity. Clin Cancer Res 2007; 13: 3933-3941. (Pubitemid 47037601)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.13
, pp. 3933-3941
-
-
Nencioni, A.1
Beck, J.2
Werth, D.3
Grunebach, F.4
Patrone, F.5
Ballestrero, A.6
Brossart, P.7
-
59
-
-
57849096553
-
The histone deacetylase HDAC11 regulates theexpression of interleukin 10and immunetolerance
-
Villagra A, Cheng F, Wang HW, Suarez I, Glozak M, Maurin M et al. The histone deacetylase HDAC11 regulates theexpression of interleukin 10and immunetolerance. Nat Immunol 2009; 10: 92-100.
-
(2009)
Nat Immunol
, vol.10
, pp. 92-100
-
-
Villagra, A.1
Cheng, F.2
Wang, H.W.3
Suarez, I.4
Glozak, M.5
Maurin, M.6
-
60
-
-
34447509697
-
Vorinostat: A new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma
-
DOI 10.1517/13543784.16.7.1111
-
Duvic M, Vu J. Vorinostat: A new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma. Expert Opin Investig Drugs 2007; 16: 1111-1120. (Pubitemid 47074165)
-
(2007)
Expert Opinion on Investigational Drugs
, vol.16
, Issue.7
, pp. 1111-1120
-
-
Duvic, M.1
Vu, J.2
-
61
-
-
79953725710
-
Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia
-
Bishton MJ, Harrison SJ, Martin BP, Mc Laughlin N, James C, Josefsson EC et al. Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia. Blood 2011; 117: 3658-3668.
-
(2011)
Blood
, vol.117
, pp. 3658-3668
-
-
Bishton, M.J.1
Harrison, S.J.2
Martin, B.P.3
Mc Laughlin, N.4
James, C.5
Josefsson, E.C.6
-
62
-
-
79952977561
-
Phase 2 trial of romidepsin in patients with peripheral T-cell lymphoma
-
Piekarz RL, Frye R, Prince HM, Kirschbaum MH, Zain J, Allen SL et al. Phase 2 trial of romidepsin in patients with peripheral T-cell lymphoma. Blood 2011; 117: 5827-5834.
-
(2011)
Blood
, vol.117
, pp. 5827-5834
-
-
Piekarz, R.L.1
Frye, R.2
Prince, H.M.3
Kirschbaum, M.H.4
Zain, J.5
Allen, S.L.6
-
63
-
-
0036301281
-
Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms
-
Sandor V, Bakke S, Robey RW, Kang MH, Blagosklonny MV, Bender J et al. Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms. Clin Cancer Res 2002; 8: 718-728. (Pubitemid 34742100)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.3
, pp. 718-728
-
-
Sandor, V.1
Bakke, S.2
Robey, R.W.3
Kang, M.H.4
Blagosklonny, M.V.5
Bender, J.6
Brooks, R.7
Piekarz, R.L.8
Tucker, E.9
Figg, W.D.10
Chan, K.K.11
Goldspiel, B.12
Fojo, A.T.13
Balcerzak, S.P.14
Bates, S.E.15
-
64
-
-
67649399669
-
Vorinostat (NSC# 701852) in patients with relapsed non-small cell lung cancer: A Wisconsin Oncology Network phase II study
-
Traynor AM, Dubey S, Eickhoff JC, Kolesar JM, Schell K, Huie MS et al. Vorinostat (NSC# 701852) in patients with relapsed non-small cell lung cancer: A Wisconsin Oncology Network phase II study. J Thorac Oncol 2009; 4: 522-526.
-
(2009)
J Thorac Oncol
, vol.4
, pp. 522-526
-
-
Traynor, A.M.1
Dubey, S.2
Eickhoff, J.C.3
Kolesar, J.M.4
Schell, K.5
Huie, M.S.6
-
65
-
-
79961134336
-
Romidepsin: In the treatment of T-cell lymphoma
-
Yang LP. Romidepsin: in the treatment of T-cell lymphoma. Drugs 2011; 71: 1469-1480.
-
(2011)
Drugs
, vol.71
, pp. 1469-1480
-
-
Yang, L.P.1
-
66
-
-
77949720337
-
Histone deacetylase inhibitors induceapoptosis in human eosinophils and neutrophils
-
Kankaanranta H, Janka-Junttila M, Ilmarinen-Salo P, Ito K, Jalonen U, Ito M et al. Histone deacetylase inhibitors induceapoptosis in human eosinophils and neutrophils. J Inflamm (Lond) 2010; 7: 9.
-
(2010)
J Inflamm (Lond)
, vol.7
, pp. 9
-
-
Kankaanranta, H.1
Janka-Junttila, M.2
Ilmarinen-Salo, P.3
Ito, K.4
Jalonen, U.5
Ito, M.6
-
67
-
-
13244252362
-
Trichostatin A attenuates airway inflammation in mouse asthma model
-
DOI 10.1111/j.1365-2222.2004.02006.x
-
Choi JH, Oh SW, Kang MS, Kwon HJ, Oh GT, Kim DY. Trichostatin A attenuates airway inflammation in mouse asthma model. Clin Exp Allergy 2005; 35: 89-96. (Pubitemid 40188276)
-
(2005)
Clinical and Experimental Allergy
, vol.35
, Issue.1
, pp. 89-96
-
-
Choi, J.-H.1
Oh, S.-W.2
Kang, M.-S.3
Kwon, H.J.4
Oh, G.-T.5
Kim, D.-Y.6
-
68
-
-
3843129768
-
Possible mechanism of action of the histone deacetylase inhibitors for the induction of differentiation of HL-60 clone 15 cells into eosinophils
-
DOI 10.1038/sj.bjp.0705869
-
Ishihara K, Hong J, Zee O, Ohuchi K. Possible mechanism of action of the histone deacetylase inhibitors for the induction of differentiation of HL-60 clone 15 cells into eosinophils. Br JPharmacol 2004; 142: 1020-1030. (Pubitemid 39037052)
-
(2004)
British Journal of Pharmacology
, vol.142
, Issue.6
, pp. 1020-1030
-
-
Ishihara, K.1
Hong, J.2
Zee, O.3
Ohuchi, K.4
-
69
-
-
33847245318
-
Differentiation of eosinophilic leukemia EoL-1 cells into eosinophils induced by histone deacetylase inhibitors
-
DOI 10.1016/j.lfs.2006.12.016, PII S0024320507000148
-
Ishihara K, Takahashi A, Kaneko M, Sugeno H, Hirasawa N, Hong J et al. Differentiation of eosinophilic leukemia Eo L-1 cells into eosinophils induced by histone deacetylase inhibitors. Life Sci 2007; 80: 1213-1220. (Pubitemid 46329010)
-
(2007)
Life Sciences
, vol.80
, Issue.13
, pp. 1213-1220
-
-
Ishihara, K.1
Takahashi, A.2
Kaneko, M.3
Sugeno, H.4
Hirasawa, N.5
Hong, J.6
Zee, O.7
Ohuchi, K.8
-
70
-
-
0037279111
-
Autoimmune lymphoproliferative syndromes: Geneticdefectsofapoptosispathways
-
Rieux-Laucat F, Le Deist F, Fischer A. Autoimmune lymphoproliferative syndromes: geneticdefectsofapoptosispathways. Cell Death Differ 2003; 10: 124-133.
-
(2003)
Cell Death Differ
, vol.10
, pp. 124-133
-
-
Rieux-Laucat, F.1
Le Deist, F.2
Fischer, A.3
-
71
-
-
77958185126
-
Phase II study of the histone deacetylase inhibitor Romidepsin in relapsed small cell lungcancer (Cancerand Leukemia Group B 30304)
-
Otterson GA, Hodgson L, Pang H, Vokes EE. Phase II study of the histone deacetylase inhibitor Romidepsin in relapsed small cell lungcancer (Cancerand Leukemia Group B 30304). J Thorac Oncol 2010; 5: 1644-1648.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 1644-1648
-
-
Otterson, G.A.1
Hodgson, L.2
Pang, H.3
Vokes, E.E.4
-
72
-
-
0037728615
-
HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis
-
DOI 10.1016/S1074-7613(03)00109-2
-
Dequiedt F, Kasler H, Fischle W, Kiermer V, Weinstein M, Herndier BG et al. HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediatedapoptosis. Immunity 2003; 18: 687-698. (Pubitemid 36588585)
-
(2003)
Immunity
, vol.18
, Issue.5
, pp. 687-698
-
-
Dequiedt, F.1
Kasler, H.2
Fischle, W.3
Kiermer, V.4
Weinstein, M.5
Herndier, B.G.6
Verdin, E.7
-
73
-
-
15444375044
-
Phosphorylation of histone deacetylase 7 by protein kinase D mediates T cell receptor-induced Nur77 expression and apoptosis
-
DOI 10.1084/jem.20042034
-
Dequiedt F, Van Lint J, Lecomte E, Van Duppen V, Seufferlein T, Vandenheede JR et al. Phosphorylation of histone deacetylase 7 by protein kinase D mediates Tcell receptor-induced Nur77 expression and apoptosis. J Exp Med 2005; 201: 793-804. (Pubitemid 40395123)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.5
, pp. 793-804
-
-
Dequiedt, F.1
Van Lint, J.2
Lecomte, E.3
Van Duppen, V.4
Seufferlein, T.5
Vandenheede, J.R.6
Wattiez, R.7
Kettmann, R.8
-
74
-
-
17144414861
-
Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation
-
DOI 10.1074/jbc.M413396200
-
Parra M, Kasler H, Mc Kinsey TA, Olson EN, Verdin E. Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation. J Biol Chem 2005; 280: 13762-13770. (Pubitemid 40517272)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.14
, pp. 13762-13770
-
-
Parra, M.1
Kasler, H.2
McKinsey, T.A.3
Olson, E.N.4
Verdin, E.5
-
75
-
-
34447532435
-
Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes
-
DOI 10.1128/MCB.02091-06
-
Kasler HG, Verdin E. Histone deacetylase 7 functions as a key regulator of genes involved in both positiveand negativeselection ofthymocytes. Mol Cell Biol 2007; 27: 5184-5200. (Pubitemid 47068292)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.14
, pp. 5184-5200
-
-
Kasler, H.G.1
Verdin, E.2
-
76
-
-
79954993361
-
Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes
-
Kasler HG, Young BD, Mottet D, Lim HW, Collins AM, Olson EN et al. Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes. JImmunol 2011; 186: 4782-4793.
-
(2011)
JImmunol
, vol.186
, pp. 4782-4793
-
-
Kasler, H.G.1
Young, B.D.2
Mottet, D.3
Lim, H.W.4
Collins, A.M.5
Olson, E.N.6
-
77
-
-
3042566927
-
The histone deacetylase inhibitor Trichostatin A modulates CD4+ Tcell responses
-
Moreira JM, Scheipers P, Sorensen P. The histone deacetylase inhibitor Trichostatin A modulates CD4+ Tcell responses. BMC Cancer 2003; 3: 30.
-
(2003)
BMC Cancer
, vol.3
, pp. 30
-
-
Moreira, J.M.1
Scheipers, P.2
Sorensen, P.3
-
78
-
-
41049100892
-
Effects of Histone Deacetylase Inhibitor SAHA on Effector and FOXP3+Regulatory T Cells in Rhesus Macaques
-
DOI 10.1016/j.transproceed.2008.01.039, PII S0041134508000870
-
Johnson J, Pahuja A, Graham M, Hering B, Hancock WW, Bansal-Pakala P. Effects of histone deacetylase inhibitor SAHAon effector and FOXP3+regulatory Tcells in rhesus macaques. Transplant Proc 2008; 40: 459-461. (Pubitemid 351419219)
-
(2008)
Transplantation Proceedings
, vol.40
, Issue.2
, pp. 459-461
-
-
Johnson, J.1
Pahuja, A.2
Graham, M.3
Hering, B.4
Hancock, W.W.5
Bansal-Pakala, P.6
-
79
-
-
4644307426
-
Modulation of renal disease in MRL/lpr mice by suberoylanilide hydroxamic acid
-
Reilly CM, Mishra N, Miller JM, Joshi D, Ruiz P, Richon VM et al. Modulation of renal disease in MRL/lpr mice by suberoylanilide hydroxamic acid. J Immunol 2004; 173: 4171-4178. (Pubitemid 39280783)
-
(2004)
Journal of Immunology
, vol.173
, Issue.6
, pp. 4171-4178
-
-
Reilly, C.M.1
Mishra, N.2
Miller, J.M.3
Joshi, D.4
Ruiz, P.5
Richon, V.M.6
Marks, P.A.7
Gilkeson, G.S.8
-
80
-
-
79952962027
-
Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes
-
Navarro MN, Goebel J, Feijoo-Carnero C, Morrice N, Cantrell DA. Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes. Nat Immunol 2011; 12: 352-361.
-
(2011)
Nat Immunol
, vol.12
, pp. 352-361
-
-
Navarro, M.N.1
Goebel, J.2
Feijoo-Carnero, C.3
Morrice, N.4
Cantrell, D.A.5
-
81
-
-
35948980739
-
Deacetylase inhibition promotes the generation and function of regulatory T cells
-
DOI 10.1038/nm1652, PII NM1652
-
Tao R, de Zoeten EF, Ozkaynak E, Chen C, Wang L, Porrett PM et al. Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med 2007; 13: 1299-1307. (Pubitemid 350073591)
-
(2007)
Nature Medicine
, vol.13
, Issue.11
, pp. 1299-1307
-
-
Tao, R.1
De Zoeten, E.F.2
Ozkaynak, E.3
Chen, C.4
Wang, L.5
Porrett, P.M.6
Li, B.7
Turka, L.A.8
Olson, E.N.9
Greene, M.I.10
Wells, A.D.11
Hancock, W.W.12
-
82
-
-
50849102708
-
The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunityin NZB/WF1 mice
-
Reilly CM, Thomas M, Gogal Jr R, Olgun S, Santo A, Sodhi R et al. The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunityin NZB/WF1 mice. JAutoimmun 2008; 31: 123-130.
-
(2008)
JAutoimmun
, vol.31
, pp. 123-130
-
-
Reilly, C.M.1
Thomas, M.2
Gogal Jr., R.3
Olgun, S.4
Santo, A.5
Sodhi, R.6
-
83
-
-
65049087913
-
Induction of Foxp3+ regulatory T cells with histone deacetylase inhibitors
-
Lucas JL, Mirshahpanah P, Haas-Stapleton E, Asadullah K, Zollner TM, Numerof RP. Induction of Foxp3+ regulatory T cells with histone deacetylase inhibitors. Cell Immunol 2009; 257: 97-104.
-
(2009)
Cell Immunol
, vol.257
, pp. 97-104
-
-
Lucas, J.L.1
Mirshahpanah, P.2
Haas-Stapleton, E.3
Asadullah, K.4
Zollner, T.M.5
Numerof, R.P.6
-
84
-
-
70349385423
-
Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis
-
Saouaf SJ, Li B, Zhang G, Shen Y, Furuuchi N, Hancock WW et al. Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis. Exp Mol Pathol 2009; 87: 99-104.
-
(2009)
Exp Mol Pathol
, vol.87
, pp. 99-104
-
-
Saouaf, S.J.1
Li, B.2
Zhang, G.3
Shen, Y.4
Furuuchi, N.5
Hancock, W.W.6
-
85
-
-
75449114277
-
Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice
-
de Zoeten EF, Wang L, Sai H, Dillmann WH, Hancock WW. Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice. Gastroenterology 2010; 138: 583-594.
-
(2010)
Gastroenterology
, vol.138
, pp. 583-594
-
-
De Zoeten, E.F.1
Wang, L.2
Sai, H.3
Dillmann, W.H.4
Hancock, W.W.5
-
86
-
-
77953810971
-
MS-275,anhistonedeacetylaseinhibitor, reduces the inflammatory reaction in rat experimental autoimmune neuritis
-
Zhang ZY,Zhang Z,Schluesener HJ MS-275,anhistonedeacetylaseinhibitor, reduces the inflammatory reaction in rat experimental autoimmune neuritis. Neuroscience 2010, 169, 370-377.
-
(2010)
Neuroscience
, vol.169
, pp. 370-377
-
-
Zhang, Z.Y.1
Zhang, Z.2
Schluesener, H.J.3
-
87
-
-
55149094300
-
Human CD25high Foxp3pos regulatory T cells differentiate into IL-17-producing cells
-
Koenen HJ, Smeets RL, Vink PM, van Rijssen E, Boots AM, Joosten I. Human CD25high Foxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 2008; 112: 2340-2352.
-
(2008)
Blood
, vol.112
, pp. 2340-2352
-
-
Koenen, H.J.1
Smeets, R.L.2
Vink, P.M.3
Van Rijssen, E.4
Boots, A.M.5
Joosten, I.6
-
88
-
-
77955277730
-
Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs
-
Akimova T, Ge G, Golovina T, Mikheeva T, Wang L, Riley JL et al. Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs. Clin Immunol 2010; 136: 348-363
-
(2010)
Clin Immunol
, vol.136
, pp. 348-363
-
-
Akimova, T.1
Ge, G.2
Golovina, T.3
Mikheeva, T.4
Wang, L.5
Riley, J.L.6
-
89
-
-
79956094244
-
Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells
-
de Zoeten EF, Wang L, Butler K, Beier UH, Akimova T, Sai H et al. Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells. Mol Cell Biol 2011; 31: 2066-2078.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 2066-2078
-
-
De Zoeten, E.F.1
Wang, L.2
Butler, K.3
Beier, U.H.4
Akimova, T.5
Sai, H.6
-
90
-
-
79952274915
-
Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival
-
Beier UH, Wang L, Bhatti TR, Liu Y, Han R, Ge G et al. Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival. Mol Cell Biol 2011; 31: 1022-1029.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1022-1029
-
-
Beier, U.H.1
Wang, L.2
Bhatti, T.R.3
Liu, Y.4
Han, R.5
Ge, G.6
-
91
-
-
78649715384
-
Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production
-
Grausenburger R, Bilic I, Boucheron N, Zupkovitz G, El-Housseiny L, Tschismarov R et al. Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production. J Immunol 2010; 185: 3489-3497.
-
(2010)
J Immunol
, vol.185
, pp. 3489-3497
-
-
Grausenburger, R.1
Bilic, I.2
Boucheron, N.3
Zupkovitz, G.4
El-Housseiny, L.5
Tschismarov, R.6
-
92
-
-
80051693245
-
Histone Deacetylase 9 Deficiency Protects against Effector T Cell-mediated Systemic Autoimmunity
-
Yan K, Cao Q, Reilly CM, Young NL, Garcia BA, Mishra N. Histone Deacetylase 9 Deficiency Protects against Effector T Cell-mediated Systemic Autoimmunity. J Biol Chem 2011; 286: 28833-28843.
-
(2011)
J Biol Chem
, vol.286
, pp. 28833-28843
-
-
Yan, K.1
Cao, Q.2
Reilly, C.M.3
Young, N.L.4
Garcia, B.A.5
Mishra, N.6
-
93
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC et al. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 2009; 325: 834-840.
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
Kumar, C.2
Gnad, F.3
Nielsen, M.L.4
Rehman, M.5
Walther, T.C.6
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