Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice

Diabetologia

Volumn 53, Issue 4, 2010, Pages 741-748

  Lee, A S ^a   Gibson, D L ^a   Zhang, Y ^a   Sham, H P ^a   Vallance, B A ^a   Dutz, J P ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

espF Citrobacter rodentium; Citrobacter rodentium; Enteric bacterial infection; Gut barrier disruption; Insulitis; Intestinal barrier; NOD mice; Type 1 diabetes

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE DEXTRAN; VIRULENCE FACTOR;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL INFECTION; BACTERIAL STRAIN; BLOOD LEVEL; C57BL 6 MOUSE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CITROBACTER RODENTIUM; CLINICAL ASSESSMENT; CONTROLLED STUDY; DIABETOGENESIS; DISEASE COURSE; ENTEROPATHY; ESCHERICHIA COLI; FLOW CYTOMETRY; GENE DELETION; GUT BARRIER DISRUPTION; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; INTESTINE MUCOSA PERMEABILITY; LYMPH NODE; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PATHOGENESIS; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; BACTERIAL INFECTIONS; CD8-POSITIVE T-LYMPHOCYTES; CITROBACTER RODENTIUM; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; FLOW CYTOMETRY; GENE REARRANGEMENT; HYPERINSULINISM; INFLAMMATION; INTESTINES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; PREDIABETIC STATE; RECEPTORS, ANTIGEN, T-CELL; SPECIES SPECIFICITY;

EID: 77949272755     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1626-y     Document Type: Article

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