-
1
-
-
79960007110
-
Mesalazine (5-aminosalicylic acid) alters faecal bacterial profiles, but not mucosal proteolytic activity in diarrhoea-predominant irritable bowel syndrome
-
C.N. Andrews, T.A. Griffiths, J. Kaufman, N. Vergnolle, M.G. Surette, and K.P. Rioux Mesalazine (5-aminosalicylic acid) alters faecal bacterial profiles, but not mucosal proteolytic activity in diarrhoea-predominant irritable bowel syndrome Aliment. Pharmacol. Ther. 34 2011 374 383
-
(2011)
Aliment. Pharmacol. Ther.
, vol.34
, pp. 374-383
-
-
Andrews, C.N.1
Griffiths, T.A.2
Kaufman, J.3
Vergnolle, N.4
Surette, M.G.5
Rioux, K.P.6
-
2
-
-
8144226856
-
The gut microbiota as an environmental factor that regulates fat storage
-
F. Bäckhed, H. Ding, T. Wang, L.V. Hooper, G.Y. Koh, A. Nagy, C.F. Semenkovich, and J.I. Gordon The gut microbiota as an environmental factor that regulates fat storage Proc. Natl. Acad. Sci. USA 101 2004 15718 15723
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15718-15723
-
-
Bäckhed, F.1
Ding, H.2
Wang, T.3
Hooper, L.V.4
Koh, G.Y.5
Nagy, A.6
Semenkovich, C.F.7
Gordon, J.I.8
-
4
-
-
77149169405
-
Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches
-
F. Barreau, C. Madre, U. Meinzer, D. Berrebi, M. Dussaillant, F. Merlin, L. Eckmann, M. Karin, G. Sterkers, and S. Bonacorsi Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches Gut 59 2010 207 217
-
(2010)
Gut
, vol.59
, pp. 207-217
-
-
Barreau, F.1
Madre, C.2
Meinzer, U.3
Berrebi, D.4
Dussaillant, M.5
Merlin, F.6
Eckmann, L.7
Karin, M.8
Sterkers, G.9
Bonacorsi, S.10
-
5
-
-
61749099040
-
Interferon-gamma regulation of intestinal epithelial permeability
-
C. Beaurepaire, D. Smyth, and D.M. McKay Interferon-gamma regulation of intestinal epithelial permeability J. Interferon Cytokine Res. 29 2009 133 144
-
(2009)
J. Interferon Cytokine Res.
, vol.29
, pp. 133-144
-
-
Beaurepaire, C.1
Smyth, D.2
McKay, D.M.3
-
6
-
-
85027945857
-
Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues
-
J.H. Bernink, C.P. Peters, M. Munneke, A.A. te Velde, S.L. Meijer, K. Weijer, H.S. Hreggvidsdottir, S.E. Heinsbroek, N. Legrand, and C.J. Buskens Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues Nat. Immunol. 14 2013 221 229
-
(2013)
Nat. Immunol.
, vol.14
, pp. 221-229
-
-
Bernink, J.H.1
Peters, C.P.2
Munneke, M.3
Te Velde, A.A.4
Meijer, S.L.5
Weijer, K.6
Hreggvidsdottir, H.S.7
Heinsbroek, S.E.8
Legrand, N.9
Buskens, C.J.10
-
7
-
-
84879402478
-
The role of the immune system in governing host-microbe interactions in the intestine
-
E.M. Brown, M. Sadarangani, and B.B. Finlay The role of the immune system in governing host-microbe interactions in the intestine Nat. Immunol. 14 2013 660 667
-
(2013)
Nat. Immunol.
, vol.14
, pp. 660-667
-
-
Brown, E.M.1
Sadarangani, M.2
Finlay, B.B.3
-
8
-
-
79955557278
-
Conventional medical management of inflammatory bowel disease
-
e2
-
D. Burger, and S. Travis Conventional medical management of inflammatory bowel disease Gastroenterology 140 2011 1827 1837 e2
-
(2011)
Gastroenterology
, vol.140
, pp. 1827-1837
-
-
Burger, D.1
Travis, S.2
-
9
-
-
84868687011
-
Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice
-
R. Caesar, C.S. Reigstad, H.K. Bäckhed, C. Reinhardt, M. Ketonen, G.O. Lundén, P.D. Cani, and F. Bäckhed Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice Gut 61 2012 1701 1707
-
(2012)
Gut
, vol.61
, pp. 1701-1707
-
-
Caesar, R.1
Reigstad, C.S.2
Bäckhed, H.K.3
Reinhardt, C.4
Ketonen, M.5
Lundén, G.O.6
Cani, P.D.7
Bäckhed, F.8
-
10
-
-
34347399563
-
Metabolic endotoxemia initiates obesity and insulin resistance
-
P.D. Cani, J. Amar, M.A. Iglesias, M. Poggi, C. Knauf, D. Bastelica, A.M. Neyrinck, F. Fava, K.M. Tuohy, and C. Chabo Metabolic endotoxemia initiates obesity and insulin resistance Diabetes 56 2007 1761 1772
-
(2007)
Diabetes
, vol.56
, pp. 1761-1772
-
-
Cani, P.D.1
Amar, J.2
Iglesias, M.A.3
Poggi, M.4
Knauf, C.5
Bastelica, D.6
Neyrinck, A.M.7
Fava, F.8
Tuohy, K.M.9
Chabo, C.10
-
11
-
-
48249125862
-
Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
-
P.D. Cani, R. Bibiloni, C. Knauf, A. Waget, A.M. Neyrinck, N.M. Delzenne, and R. Burcelin Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice Diabetes 57 2008 1470 1481
-
(2008)
Diabetes
, vol.57
, pp. 1470-1481
-
-
Cani, P.D.1
Bibiloni, R.2
Knauf, C.3
Waget, A.4
Neyrinck, A.M.5
Delzenne, N.M.6
Burcelin, R.7
-
12
-
-
84862986986
-
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
-
D. Cipolletta, M. Feuerer, A. Li, N. Kamei, J. Lee, S.E. Shoelson, C. Benoist, and D. Mathis PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells Nature 486 2012 549 553
-
(2012)
Nature
, vol.486
, pp. 549-553
-
-
Cipolletta, D.1
Feuerer, M.2
Li, A.3
Kamei, N.4
Lee, J.5
Shoelson, S.E.6
Benoist, C.7
Mathis, D.8
-
13
-
-
73349099737
-
A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota
-
Y. Cong, T. Feng, K. Fujihashi, T.R. Schoeb, and C.O. Elson A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota Proc. Natl. Acad. Sci. USA 106 2009 19256 19261
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 19256-19261
-
-
Cong, Y.1
Feng, T.2
Fujihashi, K.3
Schoeb, T.R.4
Elson, C.O.5
-
14
-
-
77955595990
-
Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation
-
C.B. de La Serre, C.L. Ellis, J. Lee, A.L. Hartman, J.C. Rutledge, and H.E. Raybould Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation Am. J. Physiol. Gastrointest. Liver Physiol. 299 2010 G440 G448
-
(2010)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.299
, pp. G440-G448
-
-
De La Serre, C.B.1
Ellis, C.L.2
Lee, J.3
Hartman, A.L.4
Rutledge, J.C.5
Raybould, H.E.6
-
15
-
-
0030048859
-
5-Aminosalicylic acid inhibits the impaired epithelial barrier function induced by gamma interferon
-
M.C. Di Paolo, M.N. Merrett, B. Crotty, and D.P. Jewell 5-Aminosalicylic acid inhibits the impaired epithelial barrier function induced by gamma interferon Gut 38 1996 115 119
-
(1996)
Gut
, vol.38
, pp. 115-119
-
-
Di Paolo, M.C.1
Merrett, M.N.2
Crotty, B.3
Jewell, D.P.4
-
16
-
-
77957880664
-
High-fat diet: Bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse
-
S. Ding, M.M. Chi, B.P. Scull, R. Rigby, N.M. Schwerbrock, S. Magness, C. Jobin, and P.K. Lund High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse PLoS ONE 5 2010 e12191
-
(2010)
PLoS ONE
, vol.5
, pp. e12191
-
-
Ding, S.1
Chi, M.M.2
Scull, B.P.3
Rigby, R.4
Schwerbrock, N.M.5
Magness, S.6
Jobin, C.7
Lund, P.K.8
-
17
-
-
84893176179
-
The intestinal epithelial insulin-like growth factor-1 receptor links glucagon-like peptide-2 action to gut barrier function
-
C.X. Dong, W. Zhao, C. Solomon, K.J. Rowland, C. Ackerley, S. Robine, M. Holzenberger, T. Gonska, and P.L. Brubaker The intestinal epithelial insulin-like growth factor-1 receptor links glucagon-like peptide-2 action to gut barrier function Endocrinology 155 2014 370 379
-
(2014)
Endocrinology
, vol.155
, pp. 370-379
-
-
Dong, C.X.1
Zhao, W.2
Solomon, C.3
Rowland, K.J.4
Ackerley, C.5
Robine, S.6
Holzenberger, M.7
Gonska, T.8
Brubaker, P.L.9
-
18
-
-
84923261268
-
Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status
-
A. Everard, L. Geurts, R. Caesar, M. Van Hul, S. Matamoros, T. Duparc, R.G. Denis, P. Cochez, F. Pierard, and J. Castel Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status Nat. Commun. 5 2014 5648
-
(2014)
Nat. Commun.
, vol.5
, pp. 5648
-
-
Everard, A.1
Geurts, L.2
Caesar, R.3
Van Hul, M.4
Matamoros, S.5
Duparc, T.6
Denis, R.G.7
Cochez, P.8
Pierard, F.9
Castel, J.10
-
19
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
M. Feuerer, L. Herrero, D. Cipolletta, A. Naaz, J. Wong, A. Nayer, J. Lee, A.B. Goldfine, C. Benoist, S. Shoelson, and D. Mathis Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters Nat. Med. 15 2009 930 939
-
(2009)
Nat. Med.
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
Naaz, A.4
Wong, J.5
Nayer, A.6
Lee, J.7
Goldfine, A.B.8
Benoist, C.9
Shoelson, S.10
Mathis, D.11
-
20
-
-
84855796468
-
Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut
-
J.H. Fritz, O.L. Rojas, N. Simard, D.D. McCarthy, S. Hapfelmeier, S. Rubino, S.J. Robertson, M. Larijani, J. Gosselin, and I.I. Ivanov Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut Nature 481 2012 199 203
-
(2012)
Nature
, vol.481
, pp. 199-203
-
-
Fritz, J.H.1
Rojas, O.L.2
Simard, N.3
McCarthy, D.D.4
Hapfelmeier, S.5
Rubino, S.6
Robertson, S.J.7
Larijani, M.8
Gosselin, J.9
Ivanov, I.I.10
-
21
-
-
79960131814
-
Identification of an innate T helper type 17 response to intestinal bacterial pathogens
-
K. Geddes, S.J. Rubino, J.G. Magalhaes, C. Streutker, L. Le Bourhis, J.H. Cho, S.J. Robertson, C.J. Kim, R. Kaul, D.J. Philpott, and S.E. Girardin Identification of an innate T helper type 17 response to intestinal bacterial pathogens Nat. Med. 17 2011 837 844
-
(2011)
Nat. Med.
, vol.17
, pp. 837-844
-
-
Geddes, K.1
Rubino, S.J.2
Magalhaes, J.G.3
Streutker, C.4
Le Bourhis, L.5
Cho, J.H.6
Robertson, S.J.7
Kim, C.J.8
Kaul, R.9
Philpott, D.J.10
Girardin, S.E.11
-
22
-
-
63449098729
-
Chylomicrons promote intestinal absorption of lipopolysaccharides
-
S. Ghoshal, J. Witta, J. Zhong, W. de Villiers, and E. Eckhardt Chylomicrons promote intestinal absorption of lipopolysaccharides J. Lipid Res. 50 2009 90 97
-
(2009)
J. Lipid Res.
, vol.50
, pp. 90-97
-
-
Ghoshal, S.1
Witta, J.2
Zhong, J.3
De Villiers, W.4
Eckhardt, E.5
-
23
-
-
77950885686
-
The effects of salsalate on glycemic control in patients with type 2 diabetes: A randomized trial
-
TINSAL-T2D (Targeting Inflammation Using Salsalate in Type 2 Diabetes) Study Team
-
A.B. Goldfine, V. Fonseca, K.A. Jablonski, L. Pyle, M.A. Staten, S.E. Shoelson TINSAL-T2D (Targeting Inflammation Using Salsalate in Type 2 Diabetes) Study Team The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial Ann. Intern. Med. 152 2010 346 357
-
(2010)
Ann. Intern. Med.
, vol.152
, pp. 346-357
-
-
Goldfine, A.B.1
Fonseca, V.2
Jablonski, K.A.3
Pyle, L.4
Staten, M.A.5
Shoelson, S.E.6
-
25
-
-
84880653498
-
IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells
-
S.Z. Hasnain, S. Tauro, I. Das, H. Tong, A.C. Chen, P.L. Jeffery, V. McDonald, T.H. Florin, and M.A. McGuckin IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells Gastroenterology 144 2013 357.e9
-
(2013)
Gastroenterology
, vol.144
, pp. 357e9
-
-
Hasnain, S.Z.1
Tauro, S.2
Das, I.3
Tong, H.4
Chen, A.C.5
Jeffery, P.L.6
McDonald, V.7
Florin, T.H.8
McGuckin, M.A.9
-
26
-
-
84874045511
-
The origins and drivers of insulin resistance
-
A.M. Johnson, and J.M. Olefsky The origins and drivers of insulin resistance Cell 152 2013 673 684
-
(2013)
Cell
, vol.152
, pp. 673-684
-
-
Johnson, A.M.1
Olefsky, J.M.2
-
27
-
-
84907481915
-
GLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering
-
F. Kahles, C. Meyer, J. Möllmann, S. Diebold, H.M. Findeisen, C. Lebherz, C. Trautwein, A. Koch, F. Tacke, N. Marx, and M. Lehrke GLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering Diabetes 63 2014 3221 3229
-
(2014)
Diabetes
, vol.63
, pp. 3221-3229
-
-
Kahles, F.1
Meyer, C.2
Möllmann, J.3
Diebold, S.4
Findeisen, H.M.5
Lebherz, C.6
Trautwein, C.7
Koch, A.8
Tacke, F.9
Marx, N.10
Lehrke, M.11
-
28
-
-
84867616398
-
High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway
-
K.A. Kim, W. Gu, I.A. Lee, E.H. Joh, and D.H. Kim High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway PLoS ONE 7 2012 e47713
-
(2012)
PLoS ONE
, vol.7
, pp. e47713
-
-
Kim, K.A.1
Gu, W.2
Lee, I.A.3
Joh, E.H.4
Kim, D.H.5
-
29
-
-
84879571464
-
Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
-
S. Kirchberger, D.J. Royston, O. Boulard, E. Thornton, F. Franchini, R.L. Szabady, O. Harrison, and F. Powrie Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model J. Exp. Med. 210 2013 917 931
-
(2013)
J. Exp. Med.
, vol.210
, pp. 917-931
-
-
Kirchberger, S.1
Royston, D.J.2
Boulard, O.3
Thornton, E.4
Franchini, F.5
Szabady, R.L.6
Harrison, O.7
Powrie, F.8
-
30
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
C.M. Larsen, M. Faulenbach, A. Vaag, A. Vølund, J.A. Ehses, B. Seifert, T. Mandrup-Poulsen, and M.Y. Donath Interleukin-1-receptor antagonist in type 2 diabetes mellitus N. Engl. J. Med. 356 2007 1517 1526
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
Vølund, A.4
Ehses, J.A.5
Seifert, B.6
Mandrup-Poulsen, T.7
Donath, M.Y.8
-
31
-
-
55849086542
-
Intestinal, adipose, and liver inflammation in diet-induced obese mice
-
H. Li, C. Lelliott, P. Håkansson, K. Ploj, A. Tuneld, M. Verolin-Johansson, L. Benthem, B. Carlsson, L. Storlien, and E. Michaëlsson Intestinal, adipose, and liver inflammation in diet-induced obese mice Metabolism 57 2008 1704 1710
-
(2008)
Metabolism
, vol.57
, pp. 1704-1710
-
-
Li, H.1
Lelliott, C.2
Håkansson, P.3
Ploj, K.4
Tuneld, A.5
Verolin-Johansson, M.6
Benthem, L.7
Carlsson, B.8
Storlien, L.9
Michaëlsson, E.10
-
32
-
-
67651171407
-
Balsalazine decreases intestinal mucosal permeability of dextran sulfate sodium-induced colitis in mice
-
X.C. Liu, Q. Mei, J.M. Xu, and J. Hu Balsalazine decreases intestinal mucosal permeability of dextran sulfate sodium-induced colitis in mice Acta Pharmacol. Sin. 30 2009 987 993
-
(2009)
Acta Pharmacol. Sin.
, vol.30
, pp. 987-993
-
-
Liu, X.C.1
Mei, Q.2
Xu, J.M.3
Hu, J.4
-
33
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
C.N. Lumeng, J.L. Bodzin, and A.R. Saltiel Obesity induces a phenotypic switch in adipose tissue macrophage polarization J. Clin. Invest. 117 2007 175 184
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
34
-
-
46749098265
-
Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice
-
M. Membrez, F. Blancher, M. Jaquet, R. Bibiloni, P.D. Cani, R.G. Burcelin, I. Corthesy, K. Macé, and C.J. Chou Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice FASEB J. 22 2008 2416 2426
-
(2008)
FASEB J.
, vol.22
, pp. 2416-2426
-
-
Membrez, M.1
Blancher, F.2
Jaquet, M.3
Bibiloni, R.4
Cani, P.D.5
Burcelin, R.G.6
Corthesy, I.7
Macé, K.8
Chou, C.J.9
-
35
-
-
84876746655
-
Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages
-
A.B. Molofsky, J.C. Nussbaum, H.E. Liang, S.J. Van Dyken, L.E. Cheng, A. Mohapatra, A. Chawla, and R.M. Locksley Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages J. Exp. Med. 210 2013 535 549
-
(2013)
J. Exp. Med.
, vol.210
, pp. 535-549
-
-
Molofsky, A.B.1
Nussbaum, J.C.2
Liang, H.E.3
Van Dyken, S.J.4
Cheng, L.E.5
Mohapatra, A.6
Chawla, A.7
Locksley, R.M.8
-
36
-
-
68349150756
-
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
S. Nishimura, I. Manabe, M. Nagasaki, K. Eto, H. Yamashita, M. Ohsugi, M. Otsu, K. Hara, K. Ueki, and S. Sugiura CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity Nat. Med. 15 2009 914 920
-
(2009)
Nat. Med.
, vol.15
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Eto, K.4
Yamashita, H.5
Ohsugi, M.6
Otsu, M.7
Hara, K.8
Ueki, K.9
Sugiura, S.10
-
37
-
-
84876771596
-
The immune system as a sensor of the metabolic state
-
J.I. Odegaard, and A. Chawla The immune system as a sensor of the metabolic state Immunity 38 2013 644 654
-
(2013)
Immunity
, vol.38
, pp. 644-654
-
-
Odegaard, J.I.1
Chawla, A.2
-
38
-
-
84886014303
-
Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: Lessons learned from animal models and human genetics
-
L. Pastorelli, C. De Salvo, J.R. Mercado, M. Vecchi, and T.T. Pizarro Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics Front. Immunol. 4 2013 280
-
(2013)
Front. Immunol.
, vol.4
, pp. 280
-
-
Pastorelli, L.1
De Salvo, C.2
Mercado, J.R.3
Vecchi, M.4
Pizarro, T.T.5
-
39
-
-
70349468054
-
Nod2 is required for the regulation of commensal microbiota in the intestine
-
T. Petnicki-Ocwieja, T. Hrncir, Y.J. Liu, A. Biswas, T. Hudcovic, H. Tlaskalova-Hogenova, and K.S. Kobayashi Nod2 is required for the regulation of commensal microbiota in the intestine Proc. Natl. Acad. Sci. USA 106 2009 15813 15818
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 15813-15818
-
-
Petnicki-Ocwieja, T.1
Hrncir, T.2
Liu, Y.J.3
Biswas, A.4
Hudcovic, T.5
Tlaskalova-Hogenova, H.6
Kobayashi, K.S.7
-
40
-
-
40449086665
-
Dose translation from animal to human studies revisited
-
S. Reagan-Shaw, M. Nihal, and N. Ahmad Dose translation from animal to human studies revisited FASEB J. 22 2008 659 661
-
(2008)
FASEB J.
, vol.22
, pp. 659-661
-
-
Reagan-Shaw, S.1
Nihal, M.2
Ahmad, N.3
-
41
-
-
84920034829
-
Perforin is a novel immune regulator of obesity-related insulin resistance
-
X.S. Revelo, S. Tsai, H. Lei, H. Luck, M. Ghazarian, H. Tsui, S.Y. Shi, S. Schroer, C. Luk, and G.H. Lin Perforin is a novel immune regulator of obesity-related insulin resistance Diabetes 64 2015 90 103
-
(2015)
Diabetes
, vol.64
, pp. 90-103
-
-
Revelo, X.S.1
Tsai, S.2
Lei, H.3
Luck, H.4
Ghazarian, M.5
Tsui, H.6
Shi, S.Y.7
Schroer, S.8
Luk, C.9
Lin, G.H.10
-
42
-
-
20944445862
-
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma
-
C. Rousseaux, B. Lefebvre, L. Dubuquoy, P. Lefebvre, O. Romano, J. Auwerx, D. Metzger, W. Wahli, B. Desvergne, and G.C. Naccari Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma J. Exp. Med. 201 2005 1205 1215
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1205-1215
-
-
Rousseaux, C.1
Lefebvre, B.2
Dubuquoy, L.3
Lefebvre, P.4
Romano, O.5
Auwerx, J.6
Metzger, D.7
Wahli, W.8
Desvergne, B.9
Naccari, G.C.10
-
43
-
-
78649693004
-
Genetics and environmental interactions shape the intestinal microbiome to promote inflammatory bowel disease versus mucosal homeostasis
-
R.B. Sartor Genetics and environmental interactions shape the intestinal microbiome to promote inflammatory bowel disease versus mucosal homeostasis Gastroenterology 139 2010 1816 1819
-
(2010)
Gastroenterology
, vol.139
, pp. 1816-1819
-
-
Sartor, R.B.1
-
44
-
-
80755159366
-
The combination of high-fat diet-induced obesity and chronic ulcerative colitis reciprocally exacerbates adipose tissue and colon inflammation
-
L.G. Teixeira, A.J. Leonel, E.C. Aguilar, N.V. Batista, A.C. Alves, C.C. Coimbra, A.V. Ferreira, A.M. de Faria, D.C. Cara, and J.I. Alvarez Leite The combination of high-fat diet-induced obesity and chronic ulcerative colitis reciprocally exacerbates adipose tissue and colon inflammation Lipids Health Dis. 10 2011 204
-
(2011)
Lipids Health Dis.
, vol.10
, pp. 204
-
-
Teixeira, L.G.1
Leonel, A.J.2
Aguilar, E.C.3
Batista, N.V.4
Alves, A.C.5
Coimbra, C.C.6
Ferreira, A.V.7
De Faria, A.M.8
Cara, D.C.9
Alvarez Leite, J.I.10
-
45
-
-
33845874101
-
An obesity-associated gut microbiome with increased capacity for energy harvest
-
P.J. Turnbaugh, R.E. Ley, M.A. Mahowald, V. Magrini, E.R. Mardis, and J.I. Gordon An obesity-associated gut microbiome with increased capacity for energy harvest Nature 444 2006 1027 1031
-
(2006)
Nature
, vol.444
, pp. 1027-1031
-
-
Turnbaugh, P.J.1
Ley, R.E.2
Mahowald, M.A.3
Magrini, V.4
Mardis, E.R.5
Gordon, J.I.6
-
46
-
-
84866547629
-
Lymphotoxin regulates commensal responses to enable diet-induced obesity
-
V. Upadhyay, V. Poroyko, T.J. Kim, S. Devkota, S. Fu, D. Liu, A.V. Tumanov, E.P. Koroleva, L. Deng, and C. Nagler Lymphotoxin regulates commensal responses to enable diet-induced obesity Nat. Immunol. 13 2012 947 953
-
(2012)
Nat. Immunol.
, vol.13
, pp. 947-953
-
-
Upadhyay, V.1
Poroyko, V.2
Kim, T.J.3
Devkota, S.4
Fu, S.5
Liu, D.6
Tumanov, A.V.7
Koroleva, E.P.8
Deng, L.9
Nagler, C.10
-
47
-
-
0029665856
-
Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue
-
N. Wagner, J. Löhler, E.J. Kunkel, K. Ley, E. Leung, G. Krissansen, K. Rajewsky, and W. Müller Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue Nature 382 1996 366 370
-
(1996)
Nature
, vol.382
, pp. 366-370
-
-
Wagner, N.1
Löhler, J.2
Kunkel, E.J.3
Ley, K.4
Leung, E.5
Krissansen, G.6
Rajewsky, K.7
Müller, W.8
-
48
-
-
78649714703
-
T-lymphocyte responses to intestinally absorbed antigens can contribute to adipose tissue inflammation and glucose intolerance during high fat feeding
-
Y. Wang, J. Li, L. Tang, Y. Wang, R. Charnigo, W. de Villiers, and E. Eckhardt T-lymphocyte responses to intestinally absorbed antigens can contribute to adipose tissue inflammation and glucose intolerance during high fat feeding PLoS ONE 5 2010 e13951
-
(2010)
PLoS ONE
, vol.5
, pp. e13951
-
-
Wang, Y.1
Li, J.2
Tang, L.3
Wang, Y.4
Charnigo, R.5
De Villiers, W.6
Eckhardt, E.7
-
49
-
-
84880496926
-
Expression and activity of the TLR4/NF-κB signaling pathway in mouse intestine following administration of a short-term high-fat diet
-
N. Wang, H. Wang, H. Yao, Q. Wei, X.M. Mao, T. Jiang, J. Xiang, and N. Dila Expression and activity of the TLR4/NF-κB signaling pathway in mouse intestine following administration of a short-term high-fat diet Exp Ther Med 6 2013 635 640
-
(2013)
Exp Ther Med
, vol.6
, pp. 635-640
-
-
Wang, N.1
Wang, H.2
Yao, H.3
Wei, Q.4
Mao, X.M.5
Jiang, T.6
Xiang, J.7
Dila, N.8
-
50
-
-
84908311821
-
Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes
-
X. Wang, N. Ota, P. Manzanillo, L. Kates, J. Zavala-Solorio, C. Eidenschenk, J. Zhang, J. Lesch, W.P. Lee, and J. Ross Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes Nature 514 2014 237 241
-
(2014)
Nature
, vol.514
, pp. 237-241
-
-
Wang, X.1
Ota, N.2
Manzanillo, P.3
Kates, L.4
Zavala-Solorio, J.5
Eidenschenk, C.6
Zhang, J.7
Lesch, J.8
Lee, W.P.9
Ross, J.10
-
51
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
S. Winer, Y. Chan, G. Paltser, D. Truong, H. Tsui, J. Bahrami, R. Dorfman, Y. Wang, J. Zielenski, and F. Mastronardi Normalization of obesity-associated insulin resistance through immunotherapy Nat. Med. 15 2009 921 929
-
(2009)
Nat. Med.
, vol.15
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
Truong, D.4
Tsui, H.5
Bahrami, J.6
Dorfman, R.7
Wang, Y.8
Zielenski, J.9
Mastronardi, F.10
-
52
-
-
70349232891
-
Obesity predisposes to Th17 bias
-
S. Winer, G. Paltser, Y. Chan, H. Tsui, E. Engleman, D. Winer, and H.M. Dosch Obesity predisposes to Th17 bias Eur. J. Immunol. 39 2009 2629 2635
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 2629-2635
-
-
Winer, S.1
Paltser, G.2
Chan, Y.3
Tsui, H.4
Engleman, E.5
Winer, D.6
Dosch, H.M.7
-
53
-
-
85027938385
-
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
-
D.A. Winer, S. Winer, L. Shen, P.P. Wadia, J. Yantha, G. Paltser, H. Tsui, P. Wu, M.G. Davidson, and M.N. Alonso B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies Nat. Med. 17 2011 610 617
-
(2011)
Nat. Med.
, vol.17
, pp. 610-617
-
-
Winer, D.A.1
Winer, S.2
Shen, L.3
Wadia, P.P.4
Yantha, J.5
Paltser, G.6
Tsui, H.7
Wu, P.8
Davidson, M.G.9
Alonso, M.N.10
-
54
-
-
79953815551
-
Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis
-
D. Wu, A.B. Molofsky, H.E. Liang, R.R. Ricardo-Gonzalez, H.A. Jouihan, J.K. Bando, A. Chawla, and R.M. Locksley Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis Science 332 2011 243 247
-
(2011)
Science
, vol.332
, pp. 243-247
-
-
Wu, D.1
Molofsky, A.B.2
Liang, H.E.3
Ricardo-Gonzalez, R.R.4
Jouihan, H.A.5
Bando, J.K.6
Chawla, A.7
Locksley, R.M.8
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