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Volumn 514, Issue 7521, 2014, Pages 237-241

Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INTERLEUKIN 22; INTERLEUKIN 22 RECEPTOR; INTERLEUKIN 23; INTERLEUKIN DERIVATIVE; INTERLEUKIN RECEPTOR; INTERLEUKIN-22; INTERLEUKIN-22 RECEPTOR; LEPTIN RECEPTOR;

EID: 84908311821     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13564     Document Type: Article
Times cited : (371)

References (30)
  • 1
    • 84866168894 scopus 로고    scopus 로고
    • Functional interactions between the gut microbiota and host metabolism
    • Tremaroli, V. & Backhed, F. Functional interactions between the gut microbiota and host metabolism. Nature 489, 242-249 (2012).
    • (2012) Nature , vol.489 , pp. 242-249
    • Tremaroli, V.1    Backhed, F.2
  • 2
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh, P. J. et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444, 1027-1031 (2006).
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1
  • 4
    • 84864118287 scopus 로고    scopus 로고
    • Immunological complications of obesity
    • Kanneganti, T. D. & Dixit, V. D. Immunological complications of obesity. Nature Immunol. 13, 707-712 (2012).
    • (2012) Nature Immunol. , vol.13 , pp. 707-712
    • Kanneganti, T.D.1    Dixit, V.D.2
  • 5
    • 77950250064 scopus 로고    scopus 로고
    • Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
    • Vijay-Kumar, M. et al. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 328, 228-231 (2010).
    • (2010) Science , vol.328 , pp. 228-231
    • Vijay-Kumar, M.1
  • 6
    • 79953048089 scopus 로고    scopus 로고
    • Regulation and functions of the IL-10 family of cytokines in inflammation and disease
    • Ouyang, W., Rutz, S., Crellin, N. K., Valdez, P. A. & Hymowitz, S. G. Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu. Rev. Immunol. 29, 71-109 (2011).
    • (2011) Annu. Rev. Immunol. , vol.29 , pp. 71-109
    • Ouyang, W.1    Rutz, S.2    Crellin, N.K.3    Valdez, P.A.4    Hymowitz, S.G.5
  • 7
    • 68249137286 scopus 로고    scopus 로고
    • Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity
    • Colonna, M. Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity. Immunity 31, 15-23 (2009).
    • (2009) Immunity , vol.31 , pp. 15-23
    • Colonna, M.1
  • 8
    • 43549114292 scopus 로고    scopus 로고
    • Mechanisms of leptin action and leptin resistance
    • Myers, M. G., Cowley, M. A. & Munzberg, H. Mechanisms of leptin action and leptin resistance. Annu. Rev. Physiol. 70, 537-556 (2008).
    • (2008) Annu. Rev. Physiol. , vol.70 , pp. 537-556
    • Myers, M.G.1    Cowley, M.A.2    Munzberg, H.3
  • 9
    • 40049083827 scopus 로고    scopus 로고
    • Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
    • Zheng, Y. et al. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nature Med. 14, 282-289 (2008).
    • (2008) Nature Med. , vol.14 , pp. 282-289
    • Zheng, Y.1
  • 10
    • 38849141814 scopus 로고    scopus 로고
    • IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis
    • Sugimoto, K. et al. IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis. J. Clin. Invest. 118, 534-544 (2008).
    • (2008) J. Clin. Invest. , vol.118 , pp. 534-544
    • Sugimoto, K.1
  • 11
    • 84861989207 scopus 로고    scopus 로고
    • Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria
    • Sonnenberg, G. F. et al. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science 336, 1321-1325 (2012).
    • (2012) Science , vol.336 , pp. 1321-1325
    • Sonnenberg, G.F.1
  • 12
    • 79952236553 scopus 로고    scopus 로고
    • Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica
    • Guo, X. et al. Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica. Mucosal Immunol. 4, 294-303 (2011).
    • (2011) Mucosal Immunol. , vol.4 , pp. 294-303
    • Guo, X.1
  • 13
    • 77955499820 scopus 로고    scopus 로고
    • + immune cells in spleen and mucosa
    • + immune cells in spleen and mucosa. J. Immunol. 185, 1177-1185 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 1177-1185
    • Van Maele, L.1
  • 15
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
    • Lord, G. M. et al. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 394, 897-901 (1998).
    • (1998) Nature , vol.394 , pp. 897-901
    • Lord, G.M.1
  • 16
    • 33847312289 scopus 로고    scopus 로고
    • A key role of leptin in the control of regulatory T cell proliferation
    • De Rosa, V. et al. A key role of leptin in the control of regulatory T cell proliferation. Immunity 26, 241-255 (2007).
    • (2007) Immunity , vol.26 , pp. 241-255
    • De Rosa, V.1
  • 17
    • 84875464349 scopus 로고    scopus 로고
    • + T cells promotes Th17 responses in systemic lupus erythematosus
    • + T cells promotes Th17 responses in systemic lupus erythematosus. J. Immunol. 190, 3054-3058 (2013).
    • (2013) J. Immunol. , vol.190 , pp. 3054-3058
    • Yu, Y.1
  • 18
    • 2542523184 scopus 로고    scopus 로고
    • Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies
    • Maaser, C. et al. Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies. Infect. Immun. 72, 3315-3324 (2004).
    • (2004) Infect. Immun. , vol.72 , pp. 3315-3324
    • Maaser, C.1
  • 19
    • 79957902145 scopus 로고    scopus 로고
    • Gut microbiome, obesity, and metabolic dysfunction
    • Tilg, H. & Kaser, A. Gut microbiome, obesity, and metabolic dysfunction. J. Clin. Invest. 121, 2126-2132 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 2126-2132
    • Tilg, H.1    Kaser, A.2
  • 20
    • 84872142459 scopus 로고    scopus 로고
    • JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation
    • Han, M. S. et al. JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation. Science 339, 218-222 (2013).
    • (2013) Science , vol.339 , pp. 218-222
    • Han, M.S.1
  • 21
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNF-α function
    • Uysal, K. T., Wiesbrock, S. M., Marino, M. W. & Hotamisligil, G. S. Protection from obesity-induced insulin resistance in mice lacking TNF-α function. Nature 389, 610-614 (1997).
    • (1997) Nature , vol.389 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 22
    • 0030864185 scopus 로고    scopus 로고
    • Targeted disruption of the tumor necrosis factor-α gene: Metabolic consequences in obese and nonobese mice
    • Ventre, J. et al. Targeted disruption of the tumor necrosis factor-α gene: metabolic consequences in obese and nonobese mice. Diabetes 46, 1526-1531 (1997).
    • (1997) Diabetes , vol.46 , pp. 1526-1531
    • Ventre, J.1
  • 23
    • 0037153158 scopus 로고    scopus 로고
    • A central role for JNK in obesity and insulin resistance
    • Hirosumi, J. et al. A central role for JNK in obesity and insulin resistance. Nature 420, 333-336 (2002).
    • (2002) Nature , vol.420 , pp. 333-336
    • Hirosumi, J.1
  • 24
    • 79551600855 scopus 로고    scopus 로고
    • 2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in mice
    • 2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in mice. Diabetes 60, 486-495 (2011).
    • (2011) Diabetes , vol.60 , pp. 486-495
    • Zhang, X.1
  • 25
    • 0037043704 scopus 로고    scopus 로고
    • 3-36 physiologically inhibits food intake
    • 3-36 physiologically inhibits food intake. Nature 418, 650-654 (2002).
    • (2002) Nature , vol.418 , pp. 650-654
    • Batterham, R.L.1
  • 27
    • 35548958265 scopus 로고    scopus 로고
    • A novel long-acting selective neuropeptide Y2 receptor polyethylene glycol-conjugated peptide agonist reduces food intake and body weight and improves glucose metabolism in rodents
    • Ortiz, A. A. et al. A novel long-acting selective neuropeptide Y2 receptor polyethylene glycol-conjugated peptide agonist reduces food intake and body weight and improves glucose metabolism in rodents. J. Pharmacol. Exp. Ther. 323, 692-700 (2007).
    • (2007) J. Pharmacol. Exp. Ther. , vol.323 , pp. 692-700
    • Ortiz, A.A.1
  • 28
    • 77955308513 scopus 로고    scopus 로고
    • Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22
    • Yang, L. et al. Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22. J. Hepatol. 53, 339-347 (2010).
    • (2010) J. Hepatol. , vol.53 , pp. 339-347
    • Yang, L.1
  • 29
    • 34347354309 scopus 로고    scopus 로고
    • Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
    • Odegaard, J. I. et al. Macrophage-specific PPARγ controls alternative activation and improves insulin resistance. Nature 447, 1116-1120 (2007).
    • (2007) Nature , vol.447 , pp. 1116-1120
    • Odegaard, J.I.1
  • 30
    • 84858020291 scopus 로고    scopus 로고
    • Fat signals - lipases and lipolysis in lipid metabolism and signaling
    • Zechner, R.et al. Fat signals - lipases and lipolysis in lipid metabolism and signaling. Cell Metab. 15, 279-291 (2012)
    • (2012) Cell Metab. , vol.15 , pp. 279-291
    • Zechner, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.