-
1
-
-
84866168894
-
Functional interactions between the gut microbiota and host metabolism
-
Tremaroli, V. & Backhed, F. Functional interactions between the gut microbiota and host metabolism. Nature 489, 242-249 (2012).
-
(2012)
Nature
, vol.489
, pp. 242-249
-
-
Tremaroli, V.1
Backhed, F.2
-
2
-
-
33845874101
-
An obesity-associated gut microbiome with increased capacity for energy harvest
-
Turnbaugh, P. J. et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444, 1027-1031 (2006).
-
(2006)
Nature
, vol.444
, pp. 1027-1031
-
-
Turnbaugh, P.J.1
-
4
-
-
84864118287
-
Immunological complications of obesity
-
Kanneganti, T. D. & Dixit, V. D. Immunological complications of obesity. Nature Immunol. 13, 707-712 (2012).
-
(2012)
Nature Immunol.
, vol.13
, pp. 707-712
-
-
Kanneganti, T.D.1
Dixit, V.D.2
-
5
-
-
77950250064
-
Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
-
Vijay-Kumar, M. et al. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 328, 228-231 (2010).
-
(2010)
Science
, vol.328
, pp. 228-231
-
-
Vijay-Kumar, M.1
-
6
-
-
79953048089
-
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
-
Ouyang, W., Rutz, S., Crellin, N. K., Valdez, P. A. & Hymowitz, S. G. Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu. Rev. Immunol. 29, 71-109 (2011).
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 71-109
-
-
Ouyang, W.1
Rutz, S.2
Crellin, N.K.3
Valdez, P.A.4
Hymowitz, S.G.5
-
7
-
-
68249137286
-
Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity
-
Colonna, M. Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity. Immunity 31, 15-23 (2009).
-
(2009)
Immunity
, vol.31
, pp. 15-23
-
-
Colonna, M.1
-
8
-
-
43549114292
-
Mechanisms of leptin action and leptin resistance
-
Myers, M. G., Cowley, M. A. & Munzberg, H. Mechanisms of leptin action and leptin resistance. Annu. Rev. Physiol. 70, 537-556 (2008).
-
(2008)
Annu. Rev. Physiol.
, vol.70
, pp. 537-556
-
-
Myers, M.G.1
Cowley, M.A.2
Munzberg, H.3
-
9
-
-
40049083827
-
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
-
Zheng, Y. et al. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nature Med. 14, 282-289 (2008).
-
(2008)
Nature Med.
, vol.14
, pp. 282-289
-
-
Zheng, Y.1
-
10
-
-
38849141814
-
IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis
-
Sugimoto, K. et al. IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis. J. Clin. Invest. 118, 534-544 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 534-544
-
-
Sugimoto, K.1
-
11
-
-
84861989207
-
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria
-
Sonnenberg, G. F. et al. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science 336, 1321-1325 (2012).
-
(2012)
Science
, vol.336
, pp. 1321-1325
-
-
Sonnenberg, G.F.1
-
12
-
-
79952236553
-
Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica
-
Guo, X. et al. Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica. Mucosal Immunol. 4, 294-303 (2011).
-
(2011)
Mucosal Immunol.
, vol.4
, pp. 294-303
-
-
Guo, X.1
-
13
-
-
77955499820
-
+ immune cells in spleen and mucosa
-
+ immune cells in spleen and mucosa. J. Immunol. 185, 1177-1185 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 1177-1185
-
-
Van Maele, L.1
-
14
-
-
84655176433
-
Leptin as an immunomodulator
-
Procaccini, C., Jirillo, E. & Matarese, G. Leptin as an immunomodulator. Mol. Aspects Med. 33, 35-45 (2012).
-
(2012)
Mol. Aspects Med.
, vol.33
, pp. 35-45
-
-
Procaccini, C.1
Jirillo, E.2
Matarese, G.3
-
15
-
-
0032572722
-
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
-
Lord, G. M. et al. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 394, 897-901 (1998).
-
(1998)
Nature
, vol.394
, pp. 897-901
-
-
Lord, G.M.1
-
16
-
-
33847312289
-
A key role of leptin in the control of regulatory T cell proliferation
-
De Rosa, V. et al. A key role of leptin in the control of regulatory T cell proliferation. Immunity 26, 241-255 (2007).
-
(2007)
Immunity
, vol.26
, pp. 241-255
-
-
De Rosa, V.1
-
17
-
-
84875464349
-
+ T cells promotes Th17 responses in systemic lupus erythematosus
-
+ T cells promotes Th17 responses in systemic lupus erythematosus. J. Immunol. 190, 3054-3058 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 3054-3058
-
-
Yu, Y.1
-
18
-
-
2542523184
-
Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies
-
Maaser, C. et al. Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies. Infect. Immun. 72, 3315-3324 (2004).
-
(2004)
Infect. Immun.
, vol.72
, pp. 3315-3324
-
-
Maaser, C.1
-
19
-
-
79957902145
-
Gut microbiome, obesity, and metabolic dysfunction
-
Tilg, H. & Kaser, A. Gut microbiome, obesity, and metabolic dysfunction. J. Clin. Invest. 121, 2126-2132 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2126-2132
-
-
Tilg, H.1
Kaser, A.2
-
20
-
-
84872142459
-
JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation
-
Han, M. S. et al. JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation. Science 339, 218-222 (2013).
-
(2013)
Science
, vol.339
, pp. 218-222
-
-
Han, M.S.1
-
21
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-α function
-
Uysal, K. T., Wiesbrock, S. M., Marino, M. W. & Hotamisligil, G. S. Protection from obesity-induced insulin resistance in mice lacking TNF-α function. Nature 389, 610-614 (1997).
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
22
-
-
0030864185
-
Targeted disruption of the tumor necrosis factor-α gene: Metabolic consequences in obese and nonobese mice
-
Ventre, J. et al. Targeted disruption of the tumor necrosis factor-α gene: metabolic consequences in obese and nonobese mice. Diabetes 46, 1526-1531 (1997).
-
(1997)
Diabetes
, vol.46
, pp. 1526-1531
-
-
Ventre, J.1
-
23
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
Hirosumi, J. et al. A central role for JNK in obesity and insulin resistance. Nature 420, 333-336 (2002).
-
(2002)
Nature
, vol.420
, pp. 333-336
-
-
Hirosumi, J.1
-
24
-
-
79551600855
-
2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in mice
-
2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in mice. Diabetes 60, 486-495 (2011).
-
(2011)
Diabetes
, vol.60
, pp. 486-495
-
-
Zhang, X.1
-
25
-
-
0037043704
-
3-36 physiologically inhibits food intake
-
3-36 physiologically inhibits food intake. Nature 418, 650-654 (2002).
-
(2002)
Nature
, vol.418
, pp. 650-654
-
-
Batterham, R.L.1
-
27
-
-
35548958265
-
A novel long-acting selective neuropeptide Y2 receptor polyethylene glycol-conjugated peptide agonist reduces food intake and body weight and improves glucose metabolism in rodents
-
Ortiz, A. A. et al. A novel long-acting selective neuropeptide Y2 receptor polyethylene glycol-conjugated peptide agonist reduces food intake and body weight and improves glucose metabolism in rodents. J. Pharmacol. Exp. Ther. 323, 692-700 (2007).
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.323
, pp. 692-700
-
-
Ortiz, A.A.1
-
28
-
-
77955308513
-
Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22
-
Yang, L. et al. Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22. J. Hepatol. 53, 339-347 (2010).
-
(2010)
J. Hepatol.
, vol.53
, pp. 339-347
-
-
Yang, L.1
-
29
-
-
34347354309
-
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
-
Odegaard, J. I. et al. Macrophage-specific PPARγ controls alternative activation and improves insulin resistance. Nature 447, 1116-1120 (2007).
-
(2007)
Nature
, vol.447
, pp. 1116-1120
-
-
Odegaard, J.I.1
-
30
-
-
84858020291
-
Fat signals - lipases and lipolysis in lipid metabolism and signaling
-
Zechner, R.et al. Fat signals - lipases and lipolysis in lipid metabolism and signaling. Cell Metab. 15, 279-291 (2012)
-
(2012)
Cell Metab.
, vol.15
, pp. 279-291
-
-
Zechner, R.1
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